7,269 research outputs found

    Avaliação das perdas minerais provocadas pelo polimento do arroz (Oryza sativa L.).

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    Esse trabalho tem como objetivo quantificar as perdas nutricionais em relação às concentrações de Fe, Zn, Cu e Mn em oito genótipos de arroz não comerciais submetidos ao beneficiamento convencional da sua forma integral

    Controle químico de plantas daninhas em algodoeiro herbáceo no Cerrado do Estado de Minas Gerais.

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    bitstream/CNPA/19697/1/COMTEC192.PD

    Evaluation of the health-related targets of the sustainable development goals in portuguese-speaking countries

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    Introdução: No contexto dos Objetivos de Desenvolvimento Sustentável, torna-se importante o monitoramento do desempenho dos países signatários. Objetivo: analisar indicadores de saúde dos Objetivos de Desenvolvimento Sustentável, estimados pelo Institute for Health Metrics and Evaluation para os Estados que integram a Comunidade dos Países de Língua Portuguesa, referentes ao ano de 2017 e projeções para 2030. Materiais e métodos: Foram utilizadas as estimativas do estudo “Carga Global de Doenças”. Para cada país, e comparativamente entre eles, foram analisados um índice que sintetiza 41 indicadores de saúde dos Objetivos de Desenvolvimento Sustentável, e os próprios indicadores, cujos valores foram transformandoos em escala de 0 a 100. Também se analisou a evolução do índice para cada país no período compreendido entre 1990 e 2017 e as tendências projetadas até o ano de 2030. Resultados: Os melhores desempenhos foram observados para Portugal e Brasil, nesta ordem. Nestes países, os maiores problemas de saúde referem-se às doenças crónicas não transmissíveis e fatores de risco correlatos, e, no Brasil,destaca-se também a violência. Nos demais países, observam-se: tripla carga de doenças, doenças infeciosas, problemas relacionados ao saneamento, elevadas taxas de mortalidade na infância, materna e por doenças crónicas não transmissíveis, além da violência sexual e agressões físicas. Conclusão: A CPLP apresenta assimetrias internas económico-sanitárias e na carga de doenças, o que torna premente o estabelecimento de uma rede de cooperação para o cumprimento da Agenda 2030. Introduction: In the context of the Sustainable Development Goals, it is important to monitor the performance of the signatory countries. Objective: This study aims at analyzing the Sustainable Development Goals’s health indicators for 2017 and projections for 2030 estimated by the Institute for Health Metrics and Evaluation, regarding the Community of Portuguese-Speaking Countries. Materials and methods: Data from the Global Burden of Disease Study were used. In order to compare countries performances, it was analyzed an index that synthesizes 41 Sustainable Development Goals’s health indicators and also the values of each indicator, rescaled to a range from 0 through 100. The evolution of the index comprising the years of 1990 to 2017 and the projected trends until the year 2030 were analyzed for each country. Results: The best performances were observed for Portugal and Brazil, in that order. In these countries, the greatest health problems are related to and related risk factors, and in Brazil violence is also highlighted. In other countries, there is a triple burden of diseases, infectious diseases, problems related to water supply and sanitation, high infant and maternal mortality rates, and high mortality rates due to noncommunicable diseases, sexual violence and physical aggression. Conclusion: The Community of Portuguese-Speaking Countries presents internal disparities concerning economic and health status and the burden of diseases, which makes it urgent to establish a cooperation network to accomplish the 2030 agenda.publishersversionpublishe

    Methods to Study Centrosomes and Cilia in Drosophila

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    The deposited item is a book chapter and is part of the series " Methods in Molecular Biology book series ([MIMB, volume 1454]) published by the publisher Humana Press.The deposited book chapter is a pre-print version and hasn't been submitted to peer reviewing.There is no public supplementary material available for this publication.This publication hasn't any creative commons license associated.Centrioles and cilia are highly conserved eukaryotic organelles. Drosophila melanogaster is a powerful genetic and cell biology model organism, extensively used to discover underlying mechanisms of centrosome and cilia biogenesis and function. Defects in centrosomes and cilia reduce fertility and affect different sensory functions, such as proprioception, olfaction, and hearing. The fly possesses a large diversity of ciliary structures and assembly modes, such as motile, immotile, and intraflagellar transport (IFT)-independent or IFT-dependent assembly. Moreover, all the diverse ciliated cells harbor centrioles at the base of the cilia, called basal bodies, making the fly an attractive model to better understand the biology of this organelle. This chapter describes protocols to visualize centrosomes and cilia by fluorescence and electron microscopy.Fundação Portuguesa para a Ciência e Tecnologia grants: (SFRH/BPD/87479/2012, SFRH/BD/52176/2013); EMBO installation grant; ERC starting grant.info:eu-repo/semantics/publishedVersio

    An SFC-enabled approach for processing SSL/TLS encrypted traffic in future enterprise networks

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    In this paper, we propose an architecture based on NFV and SDN which allows to balance traffic analysis techniques using a Classifier. It steers flows to the appropriate Service Function Chaining (to open traffic or not) according to network requirements (such as, effectiveness, flexibility, scalability, performance, and privacy). The SSL/TLS traffic processing is carried-out by the centerpiece of this work, the SFC-enabled MITM. A Proof-of-Concept was conducted (focusing on our SFC-enabled MITM) which showed that functionalities lost due to encryption (Content Optimization, Caching, Network Anti-virus, and Content Filter) were recovered when processing opened traffic within its Service Function Chains. We also evaluated its impact on performance. The results show that cipher suite overhead plays a role but can be mitigated, the Classifier can alleviate the performance overhead of different traffic analysis techniques, network functions have lower impact to performance, and Service Function Chaining length influences page load time.publishe

    Procedimentos para indução de calos embriogênicos em algodão.

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    bitstream/CNPA/18348/1/CIRTEC103.pd

    Orchestrating an SFC-enabled SSL/TLS traffic processing architecture using MANO

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    The heterogeneity of 5G requirements commands more complex network architectures, imposing the need for network orchestration. ETSI NFV MANO is the standard which defines a common framework for vendors and operators to integrate their orchestration efforts. In this paper, we evaluated how an ETSI NFV MANO compliant orchestrator (OSM) fares while orchestrating an SFC-enabled SSL/TLS encrypted traffic processing architecture, which supports both edge and cloud deployments. A quantitative evaluation was carried-out, which assessed the responsiveness and overheads of OSM, as well as the actual functionality of our SSL/TLS processing architecture (with edge computing components). A qualitative evaluation was also carried-out, providing insight into the maturity of the current OSM release, what works well, what requires workarounds, and the actual limitations. A demonstration of the architecture evaluated in this work was accepted as a contribution to the ETSI OSM PoC Framework.publishe

    Stepwise evolution of the centriole-assembly pathway

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    The centriole and basal body (CBB) structure nucleates cilia and flagella, and is an essential component of the centrosome, underlying eukaryotic microtubule-based motility, cell division and polarity. In recent years, components of the CBB-assembly machinery have been identified, but little is known about their regulation and evolution. Given the diversity of cellular contexts encountered in eukaryotes, but the remarkable conservation of CBB morphology, we asked whether general mechanistic principles could explain CBB assembly. We analysed the distribution of each component of the human CBB-assembly machinery across eukaryotes as a strategy to generate testable hypotheses. We found an evolutionarily cohesive and ancestral module, which we term UNIMOD and is defined by three components (SAS6, SAS4/CPAP and BLD10/CEP135), that correlates with the occurrence of CBBs. Unexpectedly, other players (SAK/PLK4, SPD2/CEP192 and CP110) emerged in a taxon-specific manner. We report that gene duplication plays an important role in the evolution of CBB components and show that, in the case of BLD10/CEP135, this is a source of tissue specificity in CBB and flagella biogenesis. Moreover, we observe extreme protein divergence amongst CBB components and show experimentally that there is loss of cross-species complementation among SAK/PLK4 family members, suggesting species-specific adaptations in CBB assembly. We propose that the UNIMOD theory explains the conservation of CBB architecture and that taxon- and tissue-specific molecular innovations, gained through emergence, duplication and divergence, play important roles in coordinating CBB biogenesis and function in different cellular contexts.Fundação Calouste Gulbenkian; Fundação para a Ciência e Tecnologia scholarships and grants: (POCI2010); Câmara Municipal de Oeiras; EMBO Installation Grant
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