Influence of human pressures on large river structure and function

A large river study was conducted as part of the Cross Departmental Research Pool (CDRP) ecological integrity project to (i) provide an overview of the macroinvertebrate faunas of large rivers, including those in deep-water habitats, and (ii) to elucidate links between these faunas, river function and anthropogenic stressors. Eleven sites on 6th-order or 7th-order rivers were sampled; four in the South Island and seven in the North Island. We measured (i) macroinvertebrate communities colonising wood, riffles (where present), littoral habitats (1.5 m deep) (ii) ecosystem metabolism using a single-station open-channel approach based on natural changes in dissolved oxygen concentration over a 24-hour period, and (iii) wood and cellulose breakdown. Relationships were investigated between these response variables and reach-scale assessments of habitat quality, underlying upstream and segment environmental variables provided in the Freshwater Environments of New Zealand (FWENZ) database, and anthropogenic pressure variables provided by the Waters of National Importance (WONI) database

River doctors: Learning from medicine to improve ecosystem management

Effective ecosystem management requires a robust methodology to analyse, remedy and avoid ecosystem damage. Here we propose that the overall conceptual framework and approaches developed over millennia in medical science and practice to diagnose, cure and prevent disease can provide an excellent template. Key principles to adopt include combining well-established assessment methods with new analytical techniques and restricting both diagnosis and treatment to qualified personnel at various levels of specialization, in addition to striving for a better mechanistic understanding of ecosystem structure and functioning, as well as identifying the proximate and ultimate causes of ecosystem impairment. In addition to applying these principles, ecosystem management would much benefit from systematically embracing how medical doctors approach and interview patients, diagnose health condition, select treatments, take follow-up measures, and prevent illness. Here we translate the overall conceptual framework from medicine into environmental terms and illustrate with examples from rivers how the systematic adoption of the individual steps proven and tested in medical practice can improve ecosystem management.EC/FP7/603629/EU/MANAGING THE EFFECTS OF MULTIPLE STRESSORS ON AQUATIC ECOSYSTEMS UNDER WATER SCARCITY/GLOBAQUAEC/FP7/603378/EU/Managing Aquatic ecosystems and water Resources under multiple Stress/MAR

Mediation analysis for a survival outcome with time-varying exposures, mediators, and confounders

We propose an approach to conduct mediation analysis for survival data with time-varying exposures, mediators, and confounders. We identify certain interventional direct and indirect effects through a survival mediational g-formula and describe the required assumptions. We also provide a feasible parametric approach along with an algorithm and software to estimate these effects. We apply this method to analyze the Framingham Heart Study data to investigate the causal mechanism of smoking on mortality through coronary artery disease. The risk ratio of smoking 30 cigarettes per day for ten years compared with no smoking on mortality is 2.34 (95 % CI = (1.44, 3.70)). Of the overall effect, 7.91% (95% CI: = 1.36%, 19.32%) is mediated by coronary artery disease. The survival mediational g-formula constitutes a powerful tool for conducting mediation analysis with longitudinal data

Effects of Weaning Date and Retained Ownership on Cow and Calf Performance and Forage Disappearance in Spring Calving Beef Systems

Researchers in North Dakota, South Dakota and Wyoming are working together to evaluate the effect of weaning calves 75 days earlier than normal and are following the calves through finishing. This report summarizes accomplishments so far. Briefly, weaning calves 75 days early (mid-August) has improved cow weight and condition score compared to cows whose calves were weaned normally (early-November). Native range forage disappearance has tended to be lower when calves were weaned early. After weaning, backgrounded early weaned steers grew faster and were more efficient. However, early weaned steers required 61 more days on feed to reach final harvest

Device-to-device communications: a performance analysis in the context of social comparison-based relaying

Device-to-device (D2D) communications are recognized as a key enabler of future cellular networks which will help to drive improvements in spectral efficiency and assist with the offload of network traffic. Among the transmission modes of D2D communications are single-hop and relay assisted multi-hop transmission. Relay-assisted D2D communications will be essential when there is an extended distance between the source and destination or when the transmit power of D2D user equipments (UEs) is constrained below a certain level. Although a number of works on relay-assisted D2D communications have been presented in the literature, most of those assume that relay nodes cooperate unequivocally. In reality, this cannot be assumed since there is little incentive to cooperate without a guarantee of future reciprocal behavior. Cooperation is a social behavior that depends on various factors, such as peer comparison, incentives, the cost to the donor and the benefit to the recipient. To incorporate the social behavior of D2D relay nodes, we consider the decision to relay using the donation game based on social comparison and characterize the probability of cooperation in an evolutionary context. We then apply this within a stochastic geometric framework to evaluate the outage probability and transmission capacity of relay assisted D2D communications. Through numerical evaluations, we investigate the performance gap between the ideal case of 100% cooperation and practical scenarios with a lower cooperation probability. It shows that practical scenarios achieve lower transmission capacity and higher outage probability than idealistic network views which assume full cooperation. After a sufficient number of generations, however, the cooperation probability follows the natural rules of evolution and the transmission performance of practical scenarios approach that of the full cooperation case, indicating that all D2D relay nodes adopt the same dominant cooperative strategy based on social comparison, without the need for enforcement by an external authority

Ketones Prevent Oxidative Impairment of Hippocampal Synaptic Integrity through K\u3csub\u3eATP\u3c/sub\u3e Channels

Dietary and metabolic therapies are increasingly being considered for a variety of neurological disorders, based in part on growing evidence for the neuroprotective properties of the ketogenic diet (KD) and ketones. Earlier, we demonstrated that ketones afford hippocampal synaptic protection against exogenous oxidative stress, but the mechanisms underlying these actions remain unclear. Recent studies have shown that ketones may modulate neuronal firing through interactions with ATP-sensitive potassium (KATP) channels. Here, we used a combination of electrophysiological, pharmacological, and biochemical assays to determine whether hippocampal synaptic protection by ketones is a consequence of KATP channel activation. Ketones dose-dependently reversed oxidative impairment of hippocampal synaptic integrity, neuronal viability, and bioenergetic capacity, and this action was mirrored by the KATP channel activator diazoxide. Inhibition of KATP channels reversed ketone-evoked hippocampal protection, and genetic ablation of the inwardly rectifying K+ channel subunit Kir6.2, a critical component of KATP channels, partially negated the synaptic protection afforded by ketones. This partial protection was completely reversed by co-application of the KATP blocker, 5-hydoxydecanoate (5HD). We conclude that, under conditions of oxidative injury, ketones induce synaptic protection in part through activation of KATP channels

The Passing of Print

This paper argues that ephemera is a key instrument of cultural memory, marking the things intended to be forgotten. This important role means that when ephemera survives, whether accidentally or deliberately, it does so despite itself. These survivals, because they evoke all those other objects that have necessarily been forgotten, can be described as uncanny. The paper is divided into three main sections. The first situates ephemera within an uncanny economy of memory and forgetting. The second focuses on ephemera at a particular historical moment, the industrialization of print in the nineteenth century. This section considers the liminal place of newspapers and periodicals in this period, positioned as both provisional media for information as well as objects of record. The third section introduces a new configuration of technologies – scanners, computers, hard disks, monitors, the various connections between them – and considers the conditions under which born-digital ephemera can linger and return. Through this analysis, the paper concludes by considering digital technologies as an apparatus of memory, setting out what is required if we are not to be doubly haunted by the printed ephemera within the digital archive

GALEX Ultraviolet Photometry of Globular Clusters in M31

We present ultraviolet photometry for globular clusters (GCs) in M31 from 15 square deg of imaging using the Galaxy Evolution Explorer (GALEX). We detect 200 and 94 GCs with certainty in the near-ultraviolet (NUV; 1750 - 2750 Angstroms) and far-ultraviolet (FUV; 1350 - 1750 Angstroms) bandpasses, respectively. Our rate of detection is about 50% in the NUV and 23% in the FUV, to an approximate limiting V magnitude of 19. Out of six clusters with [Fe/H]>-1 seen in the NUV, none is detected in the FUV bandpass. Furthermore, we find no candidate metal-rich clusters with significant FUV flux, because of the contribution of blue horizontal-branch (HB) stars, such as NGC 6388 and NGC 6441, which are metal-rich Galactic GCs with hot HB stars. We show that our GALEX photometry follows the general color trends established in previous UV studies of GCs in M31 and the Galaxy. Comparing our data with Galactic GCs in the UV and with population synthesis models, we suggest that the age range of M31 and Galactic halo GCs are similar.Comment: This paper will be published as part of the Galaxy Evolution Explorer (GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of papers will be available at http://www.galex.caltech.edu/PUBLICATIONS/ after November 22, 200

UV emission and Star Formation in Stephan's Quintet

we present the first GALEX UV images of the well known interacting group of galaxies, Stephan's Quintet (SQ). We detect widespread UV emission throughout the group. However, there is no consistent coincidence between UV structure and emission in the optical, H\alpha, or HI. Excluding the foreground galaxy NGC7320 (Sd), most of the UV emission is found in regions associated with the two spiral members of the group, NGC7319 and NGC7318b, and the intragroup medium starburst SQ-A. The extinction corrected UV data are analyzed to investigate the overall star formation activity in SQ. It is found that the total star formation rate (SFR) of SQ is 6.69+-0.65 M_\sun/yr. Among this, 1.34+-0.16 M_sun/yr is due to SQ-A. This is in excellent agreement with that derived from extinction corrected H\alpha luminosity of SQ-A. The SFR in regions related to NGC 7319 is 1.98+-0.58 M_\sun/yr, most of which(68%) is contributed by the disk. The contribution from the 'young tail' is only 15%. In the UV, the 'young tail' is more extended (~100 kpc) and shows a loop-like structure, including the optical tail, the extragalactic HII regions recently discovered in H\alpha, and other UV emission regions discovered for the first time. The UV and optical colors of the 'old tail' are consistent with a single stellar population of age t ~10^{8.5+-0.4} yrs. The UV emission associated with NGC 7318b is found in a very large (~80 kpc) disk, with a net SFR of 3.37+-0.25 M_sun/yr. Several large UV emission regions are 30 -- 40 kpc away from the nucleus of NGC7318b. Although both NGC7319 and NGC7318b show peculiar UV morphology, their SFR is consistent with that of normal Sbc galaxies, indicating that the strength of star formation activity is not enhenced by interactions.Comment: This paper will be published as part of the Galaxy Evolution Explorer(GALEX) Astrophysical Journal Letters Special Issue. Links to the full set of papers will be available at http:/www.galex.caltech.edu/PUBLICATIONS/ after November 22, 200