Adiponectin : An indicator for metabolic syndrome

Our research group would like to thank all subjects who took part in current study. The project was financially supported by the Iran University of Medical Sciences. (93-02-27-24976)Peer reviewedPublisher PD

The effect of vitamin C supplementation on mood status in adults : a systematic review and meta-analysis of randomized controlled clinical trials

OBJECTIVE: We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to clarify the effect of vitamin C supplementation on mood in both depressed and non-depressed populations. METHODS: A systematic search of PubMed, EMBASE, ISI web of science and Scopus databases was conducted, from inception to 1 March 2020. Random-effects meta-analyses were used to estimate the effect size (as Hedge's g) of vitamin C supplementation on depressive symptoms. RESULTS: Finding from 10 trials with 836 participants revealed no significant improvement in mood status in overall analysis (n = 10, Hedge's g = 0.09; 95% confidence interval: -0.15 to 0.33; P = 0.465). However, subgroup analysis showed beneficial effects of vitamin C supplementation in patients who were not prescribed antidepressants (subclinical depressed) (n = 5, Hedge's g: -0.18; 95% CI: -0.35, -0.01, P = 0.041; I2 = 0.00%,). CONCLUSIONS: Although no significant effect on mood status was observed in overall population, this meta-analysis tentatively suggests that vitamin C may produce mood-elevating effects in patients with subclinical depression. Further research is recommended to reach a firm conclusion. PROTOCOL REGISTRATION: The study protocol was registered in the international prospective register of systematic reviews database (http://www.crd.york.ac.uk/PROSPERO, registration no: CRD42018086677)

Body Composition in Healthy Obese/Overweight and Normal Weight Subjects Compared to Patients with Metabolic Syndrome

Background: According to previous studies, patient with metabolic syndrome (MetS) are different in terms of body composition from healthy subjects. The purpose of the present study was to determine the body composition of healthy obese/overweight patients and compared them with those having MetS. Methods: A case-control study was conducted on both men and women aged 20 to 55 years, who were selected using sequential sampling method, based on the inclusion and exclusion criteria, from those referred to an endocrinology and the diabetes clinic affiliated to Tehran University of Medical Sciences. One hundred and forty seven subjects were enrolled in the study and divided into three groups, including 49 with MetS, 49 obese/overweight subjects without MetS, and 49 were normal weight subjects. Body composition was measured for all subjects using bioelectrical impedance analysis. NCEP ATP III was the criterion for definition of Mets. Results: No significant differences were found between the study groups in terms of demographic variables. The mean of the waist circumference (WC) was higher in MetS patients (P < 0.05) as compared with the control groups. Obese/overweight group had higher percentage of body fat and lower fat free mass than normal weight group (P < 0.05). Conclusion: Obese/overweight patients with and without MetS had significantly higher fat mass and WC than normal weight controls, while only WC was higher in MetS group as compared with obese/overweight patients without MetS. Therefore, reduction in body fat and WC should be emphasized in patients with MetS

Relation of Healthy Eating Index with Body Composition Parameters in Iranian Adult

Background: Obesity as the excessive accumulation of adipose in adipocytes has still remained equivocal. Since diets contain many components to prevent from or promote diseases, assessing effects of the whole diet on health can be more practical. The purpose of this study was to investigate the association between quality of diets through healthy eating index (HEI), and body composition parameters in Iranian adults. Methods: This cross-sectional study included a total of 138 participants in the age range of 20-55 years, who referred to Endocrinology Center of Tehran University of Medical Sciences to receive health care services and fulfilled the eligibility criteria to participate in this study. Food frequency questionnaire (FFQ) was used to calculate HEI scores. Body composition data included: Fat mass (FM), fat free mass (FFM), abdominal fat (AF), muscle mass (MM), and total body water (TBW) that were collected by bioelectrical impedance instrument. Results: In this study the mean HEI score was 55.26. Based on HEI-2010 values, diet quality was good in 0.7% of participants, needed improvement in 55.9%, and was poor in 43.4% of the cases. There were significant linear trends between quality of diets and body composition parameters (P < 0.05). Conclusion: According to our study poor diet quality can be related to FM and obesity in Iranian adults

Correlation between Diet Quality and Metabolic Syndrome

Background: The metabolic syndrome (MetS) is increasing with an alarming rate world wide. Since diet components' studies that focus on MetS have produced largely inconsistent results, assessing the whole diet than single nutrients on health can be more practical. The purpose of this study was to determine the association between diet quality and MetS components. Methods: This cross-sectional study included a total of 152 participants aged 20-55 years recruited from the endocrinology center of Tehran University of medical sciences. Dietary intake assessed by food frequency questionnaire (FFQ) was used to calculate healthy eating index 2010 (HEI-2010). Body mass index (BMI), weight, height, waist circumference, high density lipoprotein-cholesterol (HDL-c), triglycerides (TG), fasting blood glucose (FBG), and blood pressure were measured. Results: In this study HEI mean score was 55.26. Based on HEI-2010 values, diet quality was good in 0.7% of participants, needed improvement in 55.9%, and was poor in 43.4% of cases. Diet quality (HEI) was significantly and linearly related with systolic and diastolic blood pressure, TG, and BMI (P < 0.05). Conclusions: According to this study, low diet quality can be related to MetS components