70 research outputs found

    Evolution of nuclear structure in neutron-rich odd-Zn isotopes and isomers

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    Collinear laser spectroscopy was performed on Zn (Z=30) isotopes at ISOLDE, CERN. The study of hyperfine spectra of nuclei across the Zn isotopic chain, N=33–49, allowed the measurement of nuclear spins for the ground and isomeric states in odd-A neutron-rich nuclei up to N=50. Exactly one long-lived (>10 ms) isomeric state has been established in each 69–79Zn isotope. The nuclear magnetic dipole moments and spectroscopic quadrupole moments are well reproduced by large-scale shell–model calculations in the f5pg9 and fpg9d5 model spaces, thus establishing the dominant term in their wave function. The magnetic moment of the intruder Iπ=1/2+ isomer in 79Zn is reproduced only if the Îœs1/2 orbital is added to the valence space, as realized in the recently developed PFSDG-U interaction. The spin and moments of the low-lying isomeric state in 73Zn suggest a strong onset of deformation at N=43, while the progression towards 79Zn points to the stability of the Z=28 and N=50 shell gaps, supporting the magicity of 78Ni

    From Calcium to Cadmium: Testing the Pairing Functional through Charge Radii Measurements of 100−130Cd

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    Differences in mean-square nuclear charge radii of 100–130Cd are extracted from high-resolution collinear laser spectroscopy of the 5s 2S1/2→5p 2P3/2 transition of the ion and from the 5s5p3P2→5s6s3S1 transition in atomic Cd. The radii show a smooth parabolic behavior on top of a linear trend and a regular odd-even staggering across the almost complete sdgh shell. They serve as a first test for a recently established new Fayans functional and show a remarkably good agreement in the trend as well as in the total nuclear charge radius

    Candida soluble cell wall ÎČ-glucan facilitates ovalbumin-induced allergic airway inflammation in mice: Possible role of antigen-presenting cells

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    <p>Abstract</p> <p>Background</p> <p>Although fungi have been implicated as initiating/deteriorating factors for allergic asthma, their contributing components have not been fully elucidated. We previously isolated soluble ÎČ-glucan from <it>Candida albicans </it>(CSBG) (Ohno et al., 2007). In the present study, the effects of CSBG exposure on airway immunopathology in the presence or absence of other immunogenic allergen was investigated <it>in vivo</it>, and their cellular mechanisms were analyzed both <it>in vivo </it>and <it>in vitro</it>.</p> <p>Methods</p> <p><it>In vivo</it>, ICR mice were divided into 4 experimental groups: vehicle, CSBG (25 ÎŒg/animal), ovalbumin (OVA: 2 ÎŒg/animal), and CSBG + OVA were repeatedly administered intratracheally. The bronchoalveolar lavage cellular profile, lung histology, levels of cytokines and chemokines in the lung homogenates, the expression pattern of antigen-presenting cell (APC)-related molecules in the lung digests, and serum immunoglobulin values were studied. <it>In vitro</it>, the impacts of CSBG (0–12.5 ÎŒg/ml) on the phenotype and function of immune cells such as splenocytes and bone marrow-derived dendritic cells (BMDCs) were evaluated in terms of cell proliferation, the surface expression of APC-related molecules, and OVA-mediated T-cell proliferating activity.</p> <p>Results</p> <p><it>In vivo</it>, repeated pulmonary exposure to CSBG induced neutrophilic airway inflammation in the absence of OVA, and markedly exacerbated OVA-related eosinophilic airway inflammation with mucus metaplasia in mice, which was concomitant with the amplified lung expression of Th2 cytokines and IL-17A and chemokines related to allergic response. Exposure to CSBG plus OVA increased the number of cells bearing MHC class II with or without CD80 in the lung compared to that of others. <it>In vitro</it>, CSBG significantly augmented splenocyte proliferation in the presence or absence of OVA. Further, CSBG increased the expression of APC-related molecules such as CD80, CD86, and DEC205 on BMDCs and amplified OVA-mediated T-cell proliferation through BMDCs.</p> <p>Conclusion</p> <p>CSBG potentiates allergic airway inflammation with maladaptive Th immunity, and this potentiation was associated with the enhanced activation of APCs including DC.</p

    Laser Spectroscopy of Neutron-Rich Tin Isotopes: A Discontinuity in Charge Radii across the N=82 Shell Closure

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    The change in mean-square nuclear charge radii ή⟹r2⟩ along the even-A tin isotopic chain 108−134Sn has been investigated by means of collinear laser spectroscopy at ISOLDE/CERN using the atomic transitions 5p2 1S0→5p6 s1P1 and 5p2 3P0→5p6s 3P1. With the determination of the charge radius of 134Sn and corrected values for some of the neutron-rich isotopes, the evolution of the charge radii across the N=82 shell closure is established. A clear kink at the doubly magic 132Sn is revealed, similar to what has been observed at N=82 in other isotopic chains with larger proton numbers, and at the N=126 shell closure in doubly magic 208Pb. While most standard nuclear density functional calculations struggle with a consistent explanation of these discontinuities, we demonstrate that a recently developed Fayans energy density functional provides a coherent description of the kinks at both doubly magic nuclei, 132Sn and 208Pb, without sacrificing the overall performance. A multiple correlation analysis leads to the conclusion that both kinks are related to pairing and surface effects

    Laser spectroscopy of cadmium isotopes towards N=50

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    Comment on "Intruder Configurations in the A=33 Isobars: Mg-33 and Al-33"

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    A Reply to the Comment by D.T. Yordanov et al. © 2010 The American Physical Society.status: publishe

    Nuclear ground-state spins and magnetic moments of Mg-27, Mg-29, and Mg-31

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    The ground-state spins and magnetic moments of neutron-rich Mg-27, Mg-29, and Mg-31 were measured for the first time with laser and beta-NMR spectroscopy at ISOLDE/CERN. The hyperfine structure of Mg-27 observed in fluorescence-confirms previous assignments of the spin I = 1/2 and reveals the magnetic moment mu(I) (Mg-27) = -0.4107(15) mu(N). The hyperfine structure and nuclear magnetic resonance of optically polarized Mg-29-observed in the asymmetry of its beta decay after implantation in a cubic crystal-give I = 3/2 and mu(I) (Mg-29) = +0.9780(6) mu(N). For Mg-31 they yield together I = 1/2 and mu(I) (Mg-31) = -0.88355(15) mu(N), where the negative magnetic moment provides evidence for a positive parity. The results for 27Mg and 29Mg agree well with shell-model calculations confined only to the sd model space, whereas the ground state of Mg-31 involves large contributions from neutrons in the pf shell, which places this nucleus inside the "island of inversion.".status: publishe

    Collinear laser spectroscopy at ISOLDE: new methods and highlights

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    Over three and a half decades of collinear laser spectroscopy and the COLLAPS setup have played a major role in the ISOLDE physics programme. Based on a general experimental principle and diverse approaches towards higher sensitivity, it has provided unique access to basic nuclear properties such as spins, magnetic moments and electric quadrupole moments as well as isotopic variations of nuclear mean square charge radii. While previous methods of outstanding sensitivity were restricted to selected chemical elements with special atomic properties or nuclear decay modes, recent developments have yielded a breakthrough in sensitivity for nuclides in wide mass ranges. These developments include the use of bunched beams from the radiofrequency quadrupole cooler–buncher ISCOOL, which allows a suppression of background by several orders of magnitude. Very recently, the combination of collinear laser spectroscopy with the principle of laser resonance ionisation took shape in the new CRIS setup, providing a very selective and efficient detection of optical resonance. We outline the basic experimental developments and discuss important results on nuclei or chains of isotopes in different mass ranges.status: publishe
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