23 research outputs found
Induction Of Cancer-Associated Fibroblast-Like Cells By Carbon Nanotubes Dictates Its Tumorigenicity
- Author
- Publication venue
- The Research Repository @ WVU
- Publication date
- 01/01/2016
- Field of study
Tumor microenvironment has been recognized as a key determinant of tumor formation and metastasis, but how tumor microenvironment is affected by nanomaterials is essentially unknown. Here, we investigated whether carbon nanotubes (CNTs), a widely used nanomaterial with known carcinogenic potential, can affect cancer-associated fibroblasts (CAFs), which are a key component of tumor microenvironment that provides necessary support for tumor growth. We show for the first time that single-walled CNT and to a lesser extent multi-walled and its COOH-functionalized form induced CAF-like cells, which are non-tumorigenic in animals, but promote tumor growth of human lung carcinoma and CNT-transformed lung epithelial cells. The mechanism by which CNT-induced CAF-like cells promote tumor growth involved the acquisition of cancer stem cells (CSCs) in cancer population. Gene knockdown experiments showed that an expression of podoplanin on CAF-like cells is essential for their effects, indicating the functional role of CAF-like cells and podoplanin in CNT tumorigenic process. Our findings unveil a novel mechanism of CNT-induced carcinogenesis through the induction of CAFlike cells that support CSCs and drive tumor formation. Our results also suggest the potential utility of podoplanin as a mechanism-based biomarker for rapid screening of carcinogenicity of CNTs and related nanomaterials for their safer design
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
- Abbas Rezaianzadeh
- Abdonas Tamosiunas
- Abdul Basit
- Abdul Hamid Zargar
- Abdullah Alkandari
- Abdullatif Husseini
- Abhijit Sen
- Abla M Sibai
- Abu Am Hanif
- Adela Chirita-Emandi
- Adelheid Weber
- Adetoyeje Y Oyeyemi
- Adewale L Oyeyemi
- Adolfo Rubinstein
- Adoubi Kassi Anicet
- Adroaldo Cesar Araujo Gaya
- Afshin Ostovar
- Agnes L Kadvan
- Agneta Sjöberg
- Agneta Yngve
- Agnès Le Port
- Agustinus Soemantri
- Agustín Perez-Londoño
- Ahmad A Zainuddin
- Ahmad Faudzi Yusoff
- Ahmad Reza Dorosty
- Ahmed A Madar
- Aida Pilav
- Aïcha Soumaré
- Akaninyene Otu
- Akihiro Yoshihara
- Akkumis Salhanova
- Akram Pourshams
- Ala'a Alkerwi
- Alain Morejon
- Alanna G da Silva
- Albertino Damasceno
- Alberto Barceló
- Alberto Palloni
- Albina A Fakhretdinova
- Alejandro Diaz
- Aleksander Giwercman
- Aleksandra Gomula
- Aleksandra Piwonska
- Alessandro Gialluisi
- Aletta E Schutte
- Alexander D Deev
- Alexandra M Cucu
- Alexandre C Pereira
- Alfonso Siani
- Alfonso Sousa-Poza
- Ali Ahmadi
- Ali Akbar Shayesteh
- Ali Esmaeili
- Ali Ghanbari
- Ali Reza Safarpour
- Alice Bonilla-Vargas
- Alicia Matijasevich
- Alina G Platonova
- Alina Kerimkulova
- Aline Meirhaeghe
- Aline P Batista
- Alireza Ansari-Moghaddam
- Alireza Khosravi
- Alireza Moslem
- Alireza Sadjadi
- Alisha N Wade
- Alison J Hayes
- Alison J Price
- Allan G Hill
- Allan Linneberg
- Almaz Sharman
- Altan Onat
- Aluisio Jd Barros
- Alun Evans
- Amalia De Curtis
- Amanda G Thrift
- Amanda J Cross
- Amaneh Shayanrad
- Ambady Ramachandran
- Amelia C Crampin
- Amina Barkat
- Amir Houshang Mehrparvar
- Amirabbas Momenan
- Ana Azevedo
- Ana B Crujeiras
- Ana Barradas-Pires
- Ana Carolina Mgn de Sá
- Ana D González-Alvarez
- Ana Henriques
- Ana I Rito
- Ana Jelaković
- Ana Maria B Menezes
- Ana P Ortiz
- Ana Paula C Cândido
- Anabela Mota-Pinto
- Anar Dushpanova
- Anastasia Markaki
- Anders Grøntved
- Andre L Guimaraes
- Andre P Kengne
- Andrea Gazzinelli
- Andrea Gualtieri
- Andrea Rodriguez-Martinez
- Andrea Rvr Horimoto
- Andrea Schneider
- Andrea Y Rodríguez
- Andrea Zentai
- Andreas Stang
- Andreia N Pizarro
- Andrew Kingston
- Andrew Reynolds
- Andrew Wong
- Andrzej Galbarczyk
- Andrzej Pająk
- Andrzej Więcek
- Anelise Reis Gaya
- Aneta Grajda
- Aneta Weres
- Anette Varbo
- Angel R Gonzalez
- Angela Chetrit
- Angela Döring
- Angela Spinelli
- Angelika Schaffrath Rosario
- Angelique Chan
- Angélica M Ochoa-Avilés
- Anie Marcil
- Anil Poudyal
- Anja L Madsen
- Anja Schienkiewitz
- Anna Bartosiewicz
- Anna Bugge
- Anna Fijalkowska
- Anna Jansson
- Anna V Alieva
- Annamari Lundqvist
- Anne A Bjerregaard
- Anne Chinnock
- Anne Juolevi
- Anne Taylor
- Anne Tjonneland
- Anneke Blokstra
- Annette J Dobson
- Annette Peters
- Annika Rosengren
- Anthony Kafatos
- Antonia Trichopoulou
- Antonio Bernabe-Ortiz
- Antonio Cabrera de León
- Antonio M Silva
- Antonio Mistretta
- Antonio Pedro Graça
- Antonio Prista
- Antonis Zampelas
- Antonisamy Belavendra
- Anu Mishra
- Anwar M Batieha
- Archie W Rayner
- Areti Triantafyllou
- Argyro Karakosta
- Ari Voutilainen
- Aristides M Machado-Rodrigues
- Arnaud Chiolero
- Aroor Bhagyalaxmi
- Arsalan Khaledifar
- Artur Mazur
- Arvind Pandey
- Arwa M Alshangiti
- Aryeh D Stein
- Asher Fawwad
- Attilio Rigotti
- Atul Trivedi
- Augustin F Beybey
- Augustine N Odili
- Augusto Di Castelnuovo
- Aung Soe Htet
- Ausra Petrauskiene
- Avula Laxmaiah
- Axel C Carlsson
- Aya Mostafa
- Ayman A Zayed
- Azaliia M Tuliakova
- Azhar Dyussupova
- Azim Nejatizadeh
- Azli Baharudin
- Åsa Ågren
- Badreya Al-Lahou
- Bagher Larijani
- Bahareh Kheiri
- Bahman Cheraghian
- Bakary Jallow
- Baltazar Nunes
- Barbara Heude
- Barbara Thorand
- Barry M Popkin
- Batyrbek Assembekov
- Beatriz D Schaan
- Bee Koon Poh
- Behrooz Hamzeh
- Bekbolat Zholdin
- Belgin Unal
- Belong Cho
- Ben Schöttker
- Benjamin Acosta-Cazares
- Benoit Salanave
- Benson M Kazembe
- Bente Sparboe-Nilsen
- Bernard Maire
- Bernardo L Horta
- Bernhard O Boehm
- Bert-Jan van den Born
- Bettina Bringolf-Isler
- Bharathi Viswanathan
- Bhawesh Koirala
- Bihungum Bista
- Bill Stavreski
- Bin Zhou
- Bing Zhang
- Birgit Linkohr
- Biruta Velika
- Blanca Sandra Ruiz-Betancourt
- Bo Werner
- Boban Mugoša
- Bogdan Wojtyniak
- Bojan Jelaković
- Bontha V Babu
- Boyd A Swinburn
- Börge Schmidt
- Branimir Leskošek
- Breige A McNulty
- Brian Oldenburg
- Brooklyn Fraser
- Bruna Gonçalves Cordeiro da Silva
- Buthaina M Alkhatib
- Børge G Nordestgaard
- Caleb Ochimana
- Calogero Saieva
- Calvin Ke
- Camilla T Damsgaard
- Carl Lachat
- Carla Menêses Hardman
- Carlo Maria Barbagallo
- Carlos A Aguilar-Salinas
- Carlos O Mendivil
- Carlos P Boissonnet
- Carmen Iñiguez
- Carolina B Tarqui-Mamani
- Caroline H Fall
- Caroline Ramos de Moura Silva
- Carsten O Schmidt
- Cassiano Ricardo Rech
- Catherine Kyobutungi
- Catterina Ferreccio
- Cecilia Björkelund
- Cecily Kelleher
- Cesar G Victora
- Cézane P Reuter
- Chandini Nekkantti
- Chao Qiang Jiang
- Charalambos A Hadjigeorgiou
- Charles Agyemang
- Charles K Mondo
- Charles Lunogelo
- Charles Sossa Jérome
- Charlie Lim
- Charlotte B Ottendahl
- Charmaine A Duante
- Charumathi Sabanayagam
- Chiara Donfrancesco
- Chien-An Sun
- Chien-Jen Chen
- Ching-Yu Cheng
- Chinh Nguyen Huu
- Chinwuba Ijoma
- Chongjian Wang
- Chris Cowell
- Christa L Lilly
- Christa Meisinger
- Christian Gieger
- Christina C Dahm
- Christina Howitt
- Christina Mavrogianni
- Christine Cameron
- Christophe Tzourio
- Christopher J Paciorek
- Chung T Nguyen
- Cihangir Erem
- Claes Ohlsson
- Clara Homs
- Claudia M Hormiga
- Cláudia S Minderico
- Clicerio González-Villalpando
- Clive Osmond
- Coimbatore Subramaniam Shanthirani
- Con Burns
- Constance Schultsz
- Constanta Huidumac Petrescu
- Cora L Craig
- Correia Júnior Marco Aurélio de Valois
- Cosmin R Cojocaru
- Cristina P Padez
- Crizian G Saar
- Cynthia M Pérez
- Cyrus Cooper
- Daan Kromhout
- Dalia Luksiene
- Damaskini Valvi
- Damian K Francis
- Dan Zhu
- Daniel Bia
- Daniel Fernández-Bergés
- Daniel Ferrante
- Daniel G Vasques
- Daniel Lemogoum
- Daniel Weghuber
- Daniela Galeone
- Daniela Kállayová
- Daniela Pierannunzio
- Daniela Rodrigues
- Daphne Lai
- Daphne Mirkopoulou
- David A Gonzalez-Chica
- David De Ridder
- David Faeh
- David Goltzman
- Davide Noto
- Davood Khalili
- Deborah C Malta
- Debra S Judge
- Deena Al Asfoor
- Deepak N Amarapurkar
- Delphine De Smedt
- Demetre Labadarios
- Denise Eldemire-Shearer
- Dermot O'Reilly
- Dénes Molnár
- Diana A Santos
- Diane T Meto
- Dianna J Magliano
- Dickman Gareta
- Diego Augusto Santos Silva
- Diego G Christofaro
- Diego Salmerón
- Diego Vanuzzo
- Dimitrios Papandreou
- Dimitrios Poulimeneas
- Dimitrios Trichopoulos
- Dirk De Bacquer
- Dirk Vanderschueren
- Dominique Cottel
- Dominique Hange
- Dong Zhao
- Dongfeng Gu
- Dora Romaguera
- Doris Stöckl
- Dorja Vocanec
- Doroteia A Höfelmann
- Dusko J Bjelica
- Dušan Grafnetter
- Duygu Islek
- Dwi Hapsari Tjandrarini
- E Shyong Tai
- Ebrahim Eftekhar
- Ebrahim Ghaderi
- Eduardo Capuano
- Eduardo Salazar Martinez
- Edward F Fottrell
- Edward Janus
- Edward W Gregg
- Edwige Landais
- Edyta Łuszczki
- Eero O Kajantie
- Efthymios Kapantais
- Eha Nurk
- Ei Ei K Nang
- Eiji Oda
- Ekaterina Chikova-Iscener
- Ekaterina Stoyanova
- Elaine Dennison
- Elaine M Murtagh
- Eldridge Ferrer
- Elena Anufrieva
- Elena Bogova
- Elena Pahomova
- Elena Sacchini
- Elena V Skoblina
- Eleonora d'Orsi
- Elias F Gudmundsson
- Elin Kolle
- Elin P Sørgjerd
- Elio Riboli
- Elisabete Ramos
- Elisabetta L Romeo
- Eliza Cinteza
- Eliza Markidou Ioannidou
- Ellina M Iakupova
- Elling Bere
- Ellis Owusu-Dabo
- Ellisiv B Mathiesen
- Elnaz Faramarzi
- Els Clays
- Else Karin Grøholt
- Elvis Oa Wambiya
- Elvynna Leong
- Elysée Claude Bika Lele
- Elzbieta Dziankowska-Zaborszczyk
- Eman Aly
- Emanuel Zitt
- Emanuela Gualdi-Russo
- Emanuela Pettenuzzo
- Emiel Hoogendijk
- Emily B Wong
- Emily Sonestedt
- Emma Ruiz Moreno
- Emmanuel Cohen
- Emmanuella Magriplis
- Eng Joo Tan
- Enguerran Macia
- Enisa Kujundzic
- Enrique Gutiérrez González
- Enzo Manzato
- Erfan Ghasemi
- Eric Monterrubio-Flores
- Erik J Timmermans
- Erik Lykke Mortensen
- Erkin Mirrakhimov
- Ertugrul Celikcan
- Eruke E Egbagbe
- Espen Bjertness
- Esteban Carmuega
- Esther Lopez-Garcia
- Esther M González-Gil
- Ethel Santacruz
- Eugène Sobngwi
- Eunice Ugel
- Eva Corpeleijn
- Eva Gerdts
- Eva Karaglani
- Eva Martos
- Evangelia Tzala
- Ewelina Czenczek-Lewandowska
- Éva Kovács
- Fabian Rohner
- Fabián Méndez
- Fabio Galvano
- Fadi J Charchar
- Fadia AlBuhairan
- Fangfang Chen
- Farahnaz Joukar
- Farhad Moradpour
- Farhad Pourfarzi
- Farhad Zamani
- Fariborz Mansour-Ghanaei
- Farid Najafi
- Farshad Farzadfar
- Farzad Hadaegh
- Fatai A Maruf
- Fatemeh Malekzadeh
- Fatima Zahra Laamiri
- Felicia Cañete
- Felipe F Casanueva
- Felipe V Cureau
- Felix Gutzwiller
- Felix K Assah
- Felix O Kaducu
- Felix P Phiri
- Fereidoun Azizi
- Fernanda Cunha Soares
- Fernando Rigo
- Fernando Rodríguez-Artalejo
- Félicité Tchibindat
- Fikru Tullu
- Flavio D Fuchs
- Flavio Nervi
- Flora Am Ukoli
- Flora Bacopoulou
- Florian Muca
- Francesco Branca
- Francesco Gianfagna
- Francesco Panza
- Francesco Pistelli
- Francis Delpeuch
- Francis Morey
- Francisco de Assis Guedes de Vasconcelos
- Francisco J Felix-Redondo
- François F Kaze
- Frank Claessens
- Frank J Rühli
- Frank Tanser
- Fred Michel Paccaud
- Fred Nuwaha
- Freda Pitakaka
- Frederic Gottrand
- Frederick C Wu
- Frøydis N Vik
- Furusawa Takuro
- G K Mini
- Gabriel M Leung
- Gabriele Eiben
- Gabriele Nagel
- Gabriella Gruden
- Gailute Bernotiene
- Galina Obreja
- Gareth Stratton
- Garry Jennings
- Garry R Brian
- Geetha R Menon
- Genc Burazeri
- Geofrey Musinguzi
- Georg Lappas
- Georg Posch
- George Ll Machado-Coelho
- George Moschonis
- George S Stergiou
- Georgia Vourli
- Georgina Gómez
- Gerald Jarnig
- Gerhard Sulo
- Gerson Ferrari
- Gert Bm Mensink
- Gilad Twig
- Gilda Estela Benitez Rolandi
- Giletta Matteo
- Giota Touloumi
- Giovanna Masala
- Giovanni de Gaetano
- Giovanni Veronesi
- Giovanni Viegi
- Giuseppe Grosso
- Gladys E Maestre
- Glen Gironella
- Godsent C Isiguzo
- Gonzalo Valdivia
- Goodarz Danaei
- Gowri Mahasampath
- Graziella Bruno
- Graziella D'Arrigo
- Grazyna Jasienska
- Gregor Jurak
- Gregor Starc
- Gregorio Varela-Moreiras
- Gretchen A Stevens
- Grethe S Tell
- Gry Schultz
- Grzegorz Sobek
- Guadalupe Echeverría
- Guadalupe Longo Abril
- Guang Ning
- Guanghui Dong
- Guansheng Ma
- Guillermo Frontera
- Guillermo Sequera
- Gul Ergor
- Gulmira Aitmurzaeva
- Gustavo Velasquez-Melendez
- Guy De Backer
- Guy Fagherazzi
- Günay Can
- Günther Fink
- Gwenaëlle Le Coroller
- Gyulli M Kazakbaeva
- Ha Tp Do
- Haakon E Meyer
- Habiba Ben Romdhane
- Haiquan Xu
- Hajer Aounallah-Skhiri
- Halima Al-Hinai
- Halyna Pavlyshyn
- Hamed Pouraram
- Hamid Hakimi
- Hamideh Sabbaghi
- Han Cg Kemper
- Hana Shimizu-Furusawa
- Hana Zamrazilová
- Hanan F Abdul Rahim
- Hanna K Tolonen
- Hanna Nalecz
- Hanno Ulmer
- Hannu Mt Uusitalo
- Hans Concin
- Hanspeter Stamm
- Harald Geiger
- Haroldo S Ferreira
- Harshpal S Sachdev
- Harunobu Nakamura
- Hassan Aguenaou
- Hazzaa M Al-Hazzaa
- Heba M Fouad
- Hedley K Quintana
- Heidi Klakk
- Helen Gonçalves
- Helena Krizan
- Helena Nogueira
- Helle-Mai Loit
- Helmut Schröder
- Heloísa Bettiol
- Henrike Galenkamp
- Henry Völzke
- Herculina S Kruger
- Herman Borghs
- Herman Schargrodsky
- Hermann Brenner
- Hermann Pohlabeln
- Hermine T Mopa
- Hélène Delisle
- Himanshu K Chaturvedi
- Hoang Van Minh
- Holger Theobald
- Hon-Yen Wu
- Hongsheng Bi
- Honor Bixby
- Hossein Poustchi
- Hsien-Ho Lin
- Huashuai Chen
- Huda M Al Hourani
- Hui Cai
- Huijun Wang
- Hung-Kwan So
- Husam F Alomirah
- Hyeon Chang Kim
- Hynek Pikhart
- Ian R Hambleton
- Ian Rouse
- Ida Maria Schmidt
- Idowu O Senbanjo
- Idris Guessous
- Igor Spiroski
- Ildar Fakhradiyev
- Ilona Nenko
- Ilpo Tapani Huhtaniemi
- Ilse Msl Khouw
- Imelda A Agdeppa
- Imperia Brajkovich
- Imran Ahmed
- Imre Janszky
- Ina S Santos
- Indah S Widyahening
- Indrapal I Meshram
- Inés Sánchez Rodríguez
- Inge Huybrechts
- Inger Ariansen
- Ingunn Holden Bergh
- Ioannis Pagkalos
- Ionela M Pascanu
- Iqbal Bata
- Iraj Mohebbi
- Iraj Nabipour
- Irene Gm van Valkengoed
- Irfan Nuhoğlu
- Irina Kovalskys
- Iris Pigeot
- Isabel O Oliveira
- Isabelle Herter-Aeberli
- Ishag Adam
- Isti I Fujiati
- Iulia Jurca Simina
- Iuliia A Rusakova
- Ivaila Y Ivanova-Pandourska
- Ivan Pećin
- Ivana Radic
- Iveta Pudule
- Ivo Rakovac
- Izet Bajramovic
- J Jaime Miranda
- Jaakko Mursu
- Jaakko Tuomilehto
- Jacek J Jóźwiak
- Jaco De Bacquer
- Jacqueline F Price
- Jacqueline Ramke
- Jakob Tarp
- Jakub Stokwiszewski
- Jalila El Ati
- James Bentham
- James E Bennett
- James P Wirth
- Jamila Abubakar Garba
- Jan A Staessen
- Jan-Walter De Neve
- Jana Klanova
- Jana Kratenova
- Jana Námešná
- Jane Dp Renner
- Janette Walton
- Janice L Lukrafka
- Janina Petkeviciene
- Janine Clarke
- Janne S Tolstrup
- Jannicke Igland
- Japhet Killewo
- Jardena J Puder
- Jari J Jokelainen
- Jaume Marrugat
- Javad Aghazadeh-Attari
- Javad Harooni
- Jawad A Al-Lawati
- Jean Claude N Mbanya
- Jean Dallongeville
- Jean Ferrieres
- Jean Woo
- Jean-Bernard Ruidavets
- Jean-Michel Gaspoz
- Jean-René M'Buyamba-Kabangu
- Jeannette Klimont
- Jeannette Lee
- Jelena Kos
- Jennifer L Baker
- Jennifer Servais
- Jenny M Kindblom
- Jeonghee Lee
- Jeongseon Kim
- Jeremy M Jacobs
- Jeroen de Bont
- Jerzy Chudek
- Jesus D Melgarejo
- Jesus Vioque
- Jesús Humberto Gómez Gómez
- Jesús Ibarluzea
- Jia Li Duan
- Jianfeng Wu
- Jiang He
- Jie Hao
- Jie Mi
- Jim I Mann
- Jin Soo Moon
- Jing Liu
- Jingli Gao
- Jitendra Jonnagaddala
- Joana Araújo
- Joana Carvalho
- Joanna Baran
- Joanne Katz
- Joany Mariño
- Joao Luiz Bastos
- Joaquin Barnoya
- João Breda
- João M Pedro
- Jochanan Stessman
- Jody C Miller
- Joel Gr Roy
- Johan G Eriksson
- Johan Sundström
- Johan Van der Heyden
- Johann Willeit
- Johanna A Otero
- Johanna Gunnlaugsdottir
- Johanna M Geleijnse
- Johannes Brug
- John Amoah
- John Tuitele
- Jolanda Hyska
- Jolanda Ma Boer
- Jolanta Slowikowska-Hilczer
- Jonathan E Shaw
- Jonathan Giovannelli
- Jordi Sunyer
- Jorge Bezerra
- Jorge Escobedo-de la Peña
- Jorge Mota
- Jorge Motta
- Jose G Boggia
- Jose Sánchez-Abanto
- Josep Redon
- Joseph Cacciottolo
- José A Casajús
- José Camolas
- José Eugenio Lozano
- José María Huerta
- José R Banegas
- Josipa Josipović
- Jost B Jonas
- Jostein Steene-Johannessen
- Jouko L Saramies
- Juan A Rivera
- Juan Francisco Miquel
- Juan J Cruz
- Juan P González-Rivas
- Judit A Repasy
- Judith Benedics
- Judith Simons
- Juel Jarani
- Juergen Breckenkamp
- Juha Auvinen
- Jukka T Salonen
- Julianne Williams
- Julie Aarestrup
- Julie Taylor
- Julio Zuñiga Cisneros
- Jun Hata
- Jun Ma
- Juraci A Cesar
- Jurate Klumbiene
- Jurate Medzioniene
- Jussi Kauhanen
- Justina Vaitkeviciute
- Justyna Godos
- Justyna Leszczak
- Justyna Wyszyńska
- Jutta Stieber
- Juvenal Soares Dias-da-Costa
- Júlio Mello
- Jürgen König
- Jyh Eiin Wong
- Jyrki K Virtanen
- Jytte Halkjær
- Jørgen Meisfjord
- K R Thankappan
- Kaare Christensen
- Kai-Uwe Saum
- Kairat Davletov
- Kairit Mikkel
- Kamarul Imran Musa
- Kamel Ajlouni
- Kaosar Afsana
- Karen Morgan
- Karen Sparrenberger
- Karen Webster-Kerr
- Kari Kuulasmaa
- Karien Stronks
- Karin De Ridder
- Karin Schindler
- Karina Mary de Paiva
- Karl J Lackner
- Karl-Heinz Herzig
- Karl-Heinz Jöckel
- Karolina Miłkowska
- Kaspar Staub
- Katarzyna Dereń
- Katharina Maruszczak
- Kathrin Wolf
- Katia Biasch
- Katia V Bloch
- Katja B Leth-Møller
- Katsuyasu Kouda
- Kazem Mohammad
- Kazi M Jamil
- Keiu Nelis
- Kelias P Msyamboza
- Kelly Samara Silva
- Kenisha Russell Jonsson
- Kenji Shibuya
- Kenneth James
- Kevin I Norton
- Khadichamo Boymatova
- Khairil Si-Ramlee
- Khanh Le Nguyen Bao
- Khem B Karki
- Khuong Quynh Long
- Kim F Michaelsen
- Kim Overvad
- Kirsten Mehlig
- Kishwar Azad
- Km Venkat Narayan
- Ko Ko Zaw
- Kodanda R Kanala
- Kodavanti Mallikharjuna Rao
- Koen Van Herck
- Konrad Jamrozik
- Konstantinos D Tambalis
- Konstantinos Gkiouras
- Kotsedi Daniel K Monyeki
- Kouamelan Doua
- Kremlin Wickramasinghe
- Krishna K Aryal
- Krista Fischer
- Kristine Allin
- Kristyna Zejglicova
- Kumiko Ohara
- Kurt Widhalm
- Kyungwon Oh
- Labros S Sidossis
- Lachmie Lall
- Lacramioara Brinduse
- Laetitia Huiart
- Laila El Ammari
- Lalka S Rangelova
- Lariane M Ono
- Larissa Pruner Marques
- Lars Ängquist
- Lars Bo Andersen
- Lars Jøran Kjerpeseth
- Lars Lind
- Lars Wichstrøm
- Laura A Rodríguez-Villamizar
- Laura Censi
- Laura Gutierrez
- Laura Lauria
- Laura Torres-Collado
- Laura-María Compañ-Gabucio
- Lauren Lissner
- Leandra Abarca-Gómez
- Leanne M Riley
- Lechaba Tshepo
- Leila B Moreira
- Leila Houti
- Lekhraj Rampal
- Lela Shengelia
- Lela Sturua
- Lena Barrera
- Leng Huat Foo
- Leo D Westbury
- Leon A Simons
- Leticia Hernandez Cadena
- Lèlita C Santos
- Li Juan Wu
- Li Yan
- Liam Smeeth
- Liang Sun
- Liang Xu
- Licia Iacoviello
- Lien Braeckevelt
- Lijuan Liu
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- Wafaie W Fawzi
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- Wan Nazaimoon Wan Mohamud
- Wei Zheng
- Wei-Cheng Lo
- Wei-Yen Lim
- Weili Yan
- Wen-Harn Pan
- Wenbin Wei
- Wendy Van Lippevelde
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- Wichai Aekplakorn
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- Winsome R Parnell
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- Xiangjun Wang
- Xiaoguang Yang
- Xiaotian Liu
- Ximena Berrios Carrasola
- Xinyi Gwee
- Xiu-Hua Guo
- Xu Lin
- Xu Ma
- Xueling Sim
- Xun Tang
- Ya Xing Wang
- Yadlapalli S Kusuma
- Yajaira Briceño
- Yang Yang
- Yanhui Dong
- Yanina Zocalo
- Yanitsa V Zhecheva
- Yannis Manios
- Yanping Li
- Yemane Berhane
- Yeunsook Rho
- Yeva Movsesyan
- Yi Song
- Yi Zeng
- Yih Chung Tham
- Yiling J Cheng
- Yin Guo
- Ying-Wei Wang
- Yingfeng Zheng
- Yn-Tz Sung
- Yong Tao
- Yonghua Hu
- Yosef Farzi
- Yoto Yotov
- Youcef Laid
- Young-Ho Khang
- Yousef Saleh Khader
- Yu-Ling Yu
- Yuan He
- Yufang Bi
- Yuki Fujita
- Yulia Balanova
- Yuliya V Solovieva
- Yuna He
- Yunjiang Yu
- Yury P Nikitin
- Yves Kameli
- Yves Martin-Prevel
- Yvonne T van der Schouw
- Zahra Mohammadi
- Zbigniew Gaciong
- Zbigniew Kulaga
- Zengchang Pang
- Zhamilya Battakova
- Zhamyila Usupova
- Zhanna Kalmatayeva
- Zhen-Yu Zhang
- Zhengming Chen
- Ziad A Abdeen
- Zivka Dika
- Zlatko Fras
- Zulfiqar A Bhutta
- Zulfiya Abdurrahmonova
- Zumin Shi
- Łukasz Kryst
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We
estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from
1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories.
Methods We used data from 3663 population-based studies with 222 million participants that measured height and
weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate
trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children
and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the
individual and combined prevalence of underweight (BMI <18·5 kg/m2) and obesity (BMI ≥30 kg/m2). For schoolaged children and adolescents, we report thinness (BMI <2 SD below the median of the WHO growth reference)
and obesity (BMI >2 SD above the median).
Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in
11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed
changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and
140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of
underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and
countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior
probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse
was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of
thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a
posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%)
with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and
obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for
both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such
as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged
children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls
in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and
42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents,
the increases in double burden were driven by increases in obesity, and decreases in double burden by declining
underweight or thinness.
Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an
increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy
nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of
underweight while curbing and reversing the increase in obesit
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
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- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
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- Howden Philip
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- Ishizaki Hinako
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- Iwakawa Shinobu
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- Izumiyama Tomohiro
- Jacintho Mark
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- Jaklevic Joseph
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- Jia Jia
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- Jones Steven
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- Kojima Kazuyasu
- Kolbe William
- Kong Yi
- Korf Ian
- Kosiura Anna
- Kou Zhaohui
- Kovar Christie L.
- Krawczyk Marie-Claude
- Kremitzki Colin
- Kremmidiotis Gabriel
- Krogh Anders
- Kronmiller Brent
- Kruchowski Scott S.
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- Lander Eric S.
- Landers Tom
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- Madabhushi Ramki
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- Tatsuyama Miho
- Tatum Owatha I.
- Taudien Stefan
- Taylor Amy
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- Thorne Rachel Diane
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- Tian Chaoguang
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- Tinsley Emma
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- Togashi Naoko
- Tomizawa Iori
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- Urban Jeremy B.
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- Vassiliev Helen
- Vastrik Imre
- Vaudin Mark
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- Viknaraja Ramya
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- Wada Hiromi
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- Wagner-McPherson Caryn
- Waldron Lenee
- Waligorski Jason E.
- Walker Davian L.
- Walker Keya
- Walker Sarah
- Wall Melanie
- Wall Randy E.
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- Watanabe Hidemi
- Watanabe Saki
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- Wickremasinghe Manosha I.
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- Williamson Helen
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- Wright Debbie
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- Wright Kristin
- Wright Rita A.
- Wu Chungen
- Wu Dongying
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- Wu Qingfa
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- Wu Xiaojing
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- Wycoff-Montenegro Melissa
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- Yakub Syed
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- Yang Huanming
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- Zeng Yixin
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- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
- Abate Kalkidan Hassen
- Abate Yohannes Habtegiorgis
- Abbafati Cristiana
- Abbasgholizadeh Rouzbeh
- Abbasi Madineh Akram
- Abbasi-Kangevari Mohsen
- Abbasian Mohammadreza
- Abbasifard Mitra
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdi Parsa
- Abdollahi Mohammad
- Abdoun Meriem
- Abdulah Deldar Morad
- Abdullahi Auwal
- Abebe Mesfin
- Abedi Aidin
- Abedi Armita
- Abegaz Tadesse M
- Abeldaño Zuñiga Roberto Ariel
- Abiodun Olumide
- Abiso Temesgen Lera
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abouzid Mohamed
- Aboye Girma Beressa
- Abreu Lucas Guimarães
- Abu-Gharbieh Eman
- Abu-Zaid Ahmed
- Abualruz Hasan
- Abubakar Bilyaminu
- Abukhadijah Hana Jihad Jihad
- Aburuz Salahdein
- Adane Mesafint Molla
- Addo Isaac Yeboah
- Addolorato Giovanni
- Adedoyin Rufus Adesoji
- Adekanmbi Victor
- Aden Bashir
- Adetunji Juliana Bunmi
- Adeyeoluwa Temitayo Esther
- Adha Rishan
- Adibi Amin
- Adnani Qorinah Estiningtyas Sakilah
- Adzigbli Leticia Akua
- Afolabi Aanuoluwapo Adeyimika
- Afolabi Rotimi Felix
- Afshin Ashkan
- Afyouni Shadi
- Afzal Muhammad Sohail
- Afzal Saira
- Agampodi Suneth Buddhika
- Agbozo Faith
- Aghamiri Shahin
- Agodi Antonella
- Agrawal Anurag
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Noah
- Ahmad Shahzaib
- Ahmad Tauseef
- Ahmed Ali
- Ahmed Anisuddin
- Ahmed Ayman
- Ahmed Luai A
- Ahmed Muktar Beshir
- Ahmed Safoora
- Ahmed Syed Anees
- Ajami Marjan
- Akalu Gizachew Taddesse
- Akara Essona Matatom
- Akbarialiabad Hossein
- Akhlaghi Shiva
- Akinosoglou Karolina
- Akinyemiju Tomi
- Akkaif Mohammed Ahmed
- Akkala Sreelatha
- Akombi-Inyang Blessing
- Al Awaidy Salah
- Al Hasan Syed Mahfuz
- AL-Ahdal Tareq Mohammed Ali
- Al-Aly Ziyad
- Al-Fatly Bassam
- Al-Gheethi Adel Ali Saeed
- Al-Habbal Khairat
- Al-Marwani Sabah
- Al-Mekhlafi Hesham M
- Al-Raddadi Rajaa M
- Al-Rifai Rami Hani
- Al-Sabah Salman Khalifah
- Al-Tawfiq Jaffar A
- Al-Wardat Mohammad Sami
- Al-Worafi Yaser Mohammed
- Al-Zyoud Walid
- Alahdab Fares
- Alalalmeh Samer O
- Alalwan Tariq A
- Alam Khurshid
- Alam Nazmul
- Alanezi Fahad Mashhour
- Alanzi Turki M
- Albakri Almaza
- AlBataineh Mohammad T
- Aldhaleei Wafa A
- Aldridge Robert W
- Alemayohu Mulubirhan Assefa
- Alemu Yihun Mulugeta
- Alhabib Khalid F
- Alhassan Robert Kaba
- Ali Abid
- Ali Amjad
- Ali Beriwan Abdulqadir
- Ali Iman
- Ali Liaqat
- Ali Mohammed Usman
- Ali Rafat
- Ali Syed Shujait Shujait
- Ali Waad
- Alicandro Gianfranco
- Alif Sheikh Mohammad
- Aljunid Syed Mohamed
- Alla François
- Almustanyir Sami
- Alomari Mahmoud A
- Alonso Jordi
- Alqahtani Jaber S
- Alqutaibi Ahmed Yaseen
- Alrawashdeh Ahmad
- Alrousan Sahel Majed
- Alshahrani Najim Z
- Altaany Zaid
- Altaf Awais
- Altirkawi Khalid A
- Aluh Deborah Oyine
- Alvis-Guzman Nelson
- Alvis-Zakzuk Nelson J
- Alwafi Hassan
- Aly Hany
- Aly Safwat
- Alzoubi Karem H
- Amaechi Uchenna Anderson
- Aman Mohammadi Masous
- Amani Reza
- Amiri Sohrab
- Amirzade-Iranaq Mohammad Hosein
- Ammirati Enrico
- Amu Hubert
- Amugsi Dickson A
- Amusa Ganiyu Adeniyi
- Ancuceanu Robert
- Anderlini Deanna
- Anderson Jason A
- Andrade Pedro Prata
- Andrei Catalina Liliana
- Andrei Tudorel
- Anenberg Susan C
- Angappan Dhanalakshmi
- Angus Colin
- Anil Abhishek
- Anil Sneha
- Anjum Afifa
- Anoushiravani Amir
- Antonazzo Ippazio Cosimo
- Antony Catherine M
- Antriyandarti Ernoiz
- Anuoluwa Boluwatife Stephen
- Anvari Davood
- Anvari Saeid
- Anwar Saleha
- Anwar Sumadi Lukman
- Anwer Razique
- Anyabolo Ekenedilichukwu Emmanuel
- Anyasodor Anayochukwu Edward
- Apostol Geminn Louis Carace
- Arabloo Jalal
- Arabzadeh Bahri Razman
- Arafat Mosab
- Aravkin Aleksandr Y
- Areda Demelash
- Aregawi Brhane Berhe
- Aremu Abdulfatai
- Armocida Benedetta
- Arndt Michael Benjamin
- Arooj Mahwish
- Artamonov Anton A
- Artanti Kurnia Dwi
- Aruleba Idowu Thomas
- Arumugam Ashokan
- Asbeutah Akram M
- Asgary Saeed
- Asgedom Akeza Awealom
- Ashbaugh Charlie
- Ashemo Mubarek Yesse
- Ashraf Tahira
- Askarinejad Amir
- Assmus Michael
- Astell-Burt Thomas
- Athar Mohammad
- Athari Seyyed Shamsadin
- Atorkey Prince
- Atreya Alok
- Aujayeb Avinash
- Ausloos Marcel
- Avila-Burgos Leticia
- Awoke Andargie Abate
- Ayala Quintanilla Beatriz Paulina
- Ayatollahi Haleh
- Ayestas Portugal Carlos
- Ayuso-Mateos Jose L
- Azadnajafabad Sina
- Azevedo Rui M S
- Azhar Gulrez Shah
- Azizi Hosein
- Azzam Ahmed Y
- Ärnlöv Johan
- Backhaus Insa Linnea
- Badar Muhammad
- Badiye Ashish D
- Bagga Arvind
- Baghdadi Soroush
- Bagheri Nasser
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- Bahrami Taghanaki Pegah
- Bai Ruhai
- Baig Atif Amin
- Baker Jennifer L
- Bakkannavar Shankar M
- Balasubramanian Madhan
- Baltatu Ovidiu Constantin
- Bam Kiran
- Bandyopadhyay Soham
- Banik Biswajit
- Banik Palash Chandra
- Banke-Thomas Aduragbemi
- Bansal Hansi
- Barchitta Martina
- Bardhan Mainak
- Bardideh Erfan
- Barker-Collo Suzanne Lyn
- Barone-Adesi Francesco
- Barqawi Hiba Jawdat
- Barrero Lope H
- Barrow Amadou
- Barteit Sandra
- Basharat Zarrin
- Basiru Afisu
- Basso João Diogo
- Bastan Mohammad-Mahdi
- Basu Sanjay
- Batchu Sai
- Batra Kavita
- Batra Ravi
- Baune Bernhard T
- Bayati Mohsen
- Bayileyegn Nebiyou Simegnew
- Bärnighausen Till Winfried
- Beaney Thomas
- Behnoush Amir Hossein
- Beiranvand Maryam
- Bekele Alehegn
- Belgaumi Uzma Iqbal
- Bell Arielle Wilder
- Bell Michelle L
- Bello Muhammad Bashir
- Bello Olorunjuwon Omolaja
- Belo Luis
- Beloukas Apostolos
- Bendak Salaheddine
- Bennett Derrick A
- Bennitt Fiona B
- Bensenor Isabela M
- Benzian Habib
- Beran Azizullah
- Berezvai Zombor
- Bernabe Eduardo
- Bernstein Robert S
- Bettencourt Paulo J G
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- Bhagavathula Akshaya Srikanth
- Bhala Neeraj
- Bhandari Dinesh
- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhaskar Sonu
- Bhat Ajay Nagesh
- Bhat Vivek
- Bhatti Gurjit Kaur
- Bhatti Jasvinder Singh
- Bhatti Manpreet S
- Bhatti Rajbir
- Bhuiyan Mohiuddin Ahmed
- Bhutta Zulfiqar A
- Bikbov Boris
- Bishai Jessica Devin
- Bisignano Catherine
- Biswas Atanu
- Biswas Bijit
- Biswas Raaj Kishore
- Bjørge Tone
- Boachie Micheal Kofi
- Boakye Hosea
- Bockarie Moses John
- Bodolica Virginia
- Bodunrin Aadam Olalekan
- Bogale Eyob Ketema
- Bolla Srinivasa Rao
- Boloor Archith
- Bonakdar Hashemi Milad
- Boppana Sri Harsha
- Bora Basara Berrak
- Borhany Hamed
- Botero Carvajal Alejandro
- Bouaoud Souad
- Boufous Soufiane
- Bourne Rupert
- Boxe Christopher
- Braithwaite Dejana
- Brant Luisa C
- Brar Amanpreet
- Brauer Michael
- Breitborde Nicholas J K
- Breitner Susanne
- Brenner Hermann
- Briko Andrey Nikolaevich
- Britton Gabrielle
- Brown Colin Stewart
- Browne Annie J
- Brunoni Andre R
- Bryazka Dana
- Bulamu Norma B
- Bulto Lemma N
- Buonsenso Danilo
- Burkart Katrin
- Burns Richard A
- Busse Reinhard
- Bustanji Yasser
- Butt Nadeem Shafique
- Butt Zahid A
- Caetano dos Santos Florentino Luciano
- Cagney Jack
- Cahuana-Hurtado Lucero
- Calina Daniela
- Campos Luciana Aparecida
- Campos-Nonato Ismael R
- Cao Chao
- Cao Fan
- Cao Yubin
- Capodici Angelo
- Carr Sinclair
- Carreras Giulia
- Carrero Juan J
- Carugno Andrea
- Carvalho Felix
- Carvalho Márcia
- Castaldelli-Maia Joao Mauricio
- Castañeda-Orjuela Carlos A
- Castelpietra Giulio
- Catalá-López Ferrán
- Catapano Alberico L
- Cattaruzza Maria Sofia
- Caye Arthur
- Cámera Luis Alberto
- Cárdenas Rosario
- Cederroth Christopher R
- Cegolon Luca
- Cenderadewi Muthia
- Cercy Kelly M
- Cerin Ester
- Chadwick Joshua
- Chakraborty Chiranjib
- Chakraborty Promit Ananyo
- Chakraborty Sandip
- Chan Jeffrey Shi Kai
- Chan Raymond N C
- Chandan Joht Singh
- Chandika Rama Mohan
- Chaturvedi Pankaj
- Chen An-Tian
- Chen Catherine S
- Chen Haowei
- Chen Meng Xuan
- Chen Mingling
- Chen Simiao
- Cheng Ching-Yu
- Cheng Esther T W
- Cherbuin Nicolas
- Chi Gerald
- Chichagi Fatemeh
- Chimed-Ochir Odgerel
- Chimoriya Ritesh
- Ching Patrick R
- Chirinos-Caceres Jesus Lorenzo
- Chitheer Abdulaal
- Cho William C S
- Chong Bryan
- Chopra Hitesh
- Chowdhury Rajiv
- Christopher Devasahayam J
- Chu Dinh-Toi
- Chukwu Isaac Sunday
- Chung Eric
- Chung Sheng-Chia
- Chutiyami Muhammad
- Cioffi Iolanda
- Cogen Rebecca M
- Cohen Aaron J
- Columbus Alyssa
- Conde Joao
- Corlateanu Alexandru
- Cortese Samuele
- Cortesi Paolo Angelo
- Costa Vera Marisa
- Costanzo Simona
- Criqui Michael H
- Cruz Jessica A
- Cruz-Martins Natália
- Culbreth Garland T
- D'Amico Emanuele
- D'Anna Lucio
- D'Oria Mario
- da Silva Alanna Gomes
- Dadras Omid
- Dai Xiaochen
- Dai Zhaoli
- Daikwo Patience Unekwuojo
- Dalli Lachlan L
- Damiani Giovanni
- Darwesh Aso Mohammad
- Das Jai K
- Das Subasish
- Dash Nihar Ranjan
- Dashti Mohsen
- Davis Weaver Nicole
- Davitoiu Dragos Virgil
- Dávila-Cervantes Claudio Alberto
- De la Hoz Fernando Pio
- de la Torre-Luque Alejandro
- De Leo Diego
- Debopadhaya Shayom
- Degenhardt Louisa
- Del Bo' Cristian
- Delgado-Enciso Ivan
- Delgado-Saborit Juana Maria
- Demoze Chalachew Kassaw
- Denova-Gutiérrez Edgar
- Dervenis Nikolaos
- Dervišević Emina
- Desai Hardik Dineshbhai
- Desai Rupak
- Devanbu Vinoth Gnana Chellaiyan
- Dewan Syed Masudur Rahman
- Dhali Arkadeep
- Dhama Kuldeep
- Dhane Amol S
- Dhimal Mandira Lamichhane
- Dhimal Meghnath
- Dhingra Sameer
- Dhulipala Vishal R
- Dhungana Raja Ram
- Dias da Silva Diana
- Diaz Daniel
- Diaz Luis Antonio
- Diaz Michael J
- Dima Adriana
- Ding Delaney D
- Dinu Monica
- Djalalinia Shirin
- do Prado Camila Bruneli
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- Do Thao Huynh Phuong
- Dodangeh Masoud
- Dohare Sushil
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- Dong Wanyue
- Dongarwar Deepa
- Dorostkar Fariba
- Dorsey E Ray
- Doshi Rajkumar
- Doshmangir Leila
- Dowou Robert Kokou
- Driscoll Tim Robert
- Dsouza Ashel Chelsea
- Dsouza Haneil Larson
- Dumith Samuel C
- Duncan Bruce B
- Duraes Andre Rodrigues
- Duraisamy Senbagam
- Dushpanova Anar
- Dzianach Paulina Agnieszka
- Dziedzic Arkadiusz Marian
- Ebrahimi Alireza
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- Ed-Dra Abdelaziz
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- Edvardsson David
- Edvardsson Kristina
- Efendi Ferry
- Eftekharimehrabad Aziz
- Eini Ebrahim
- Ekholuenetale Michael
- Ekundayo Temitope Cyrus
- El Arab Rabie Adel
- El Sayed Zaki Maysaa
- El-Dahiyat Faris
- Elemam Noha Mousaad
- Elgar Frank J
- ElGohary Ghada Metwally Tawfik
- Elhabashy Hala Rashad
- Elhadi Muhammed
- Elmehrath Ahmed O
- Elmeligy Omar Abdelsadek Abdou
- Elshaer Mohammed
- Elsohaby Ibrahim
- Emeto Theophilus I
- Esfandiari Negin
- Eshrati Babak
- Eslami Majid
- Esmaeili Sayed Vahid
- Estep Kara
- Etaee Farshid
- Fabin Natalia
- Fagbamigbe Adeniyi Francis
- Fagbule Omotayo Francis
- Fahimi Saman
- Falzone Luca
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- Farinha Carla Sofia e Sá
- Faris MoezAlIslam Ezzat Mahmoud
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- Faro Andre
- Fasina Folorunso Oludayo
- Fatehizadeh Ali
- Fauk Nelsensius Klau
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- Feigin Valery L
- Feng Xiaoqi
- Fereshtehnejad Seyed-Mohammad
- Feroze Abdullah Hamid
- Ferrara Pietro
- Ferrari Alize J
- Ferreira Nuno
- Fetensa Getahun
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- Filip Irina
- Fischer Florian
- Fitriana Ida
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- Flor Luisa S
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- Force Lisa M
- Fortuna Daniela
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- Franklin Richard Charles
- Freitas Alberto
- Friedman Sara D
- Fux Blima
- G Sridevi
- Gaal Peter Andras
- Gaihre Santosh
- Gajdács Márió
- Gakidou Emmanuela
- Galali Yaseen
- Gallus Silvano
- Gandhi Aravind P
- Ganesan Balasankar
- Ganiyani Mohammad Arfat
- Garcia Vanessa
- Gardner William M
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- Gebi Tilaye Gebru
- Gebregergis Miglas W
- Gebrehiwot Mesfin
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- Gebremeskel Teferi Gebru
- Gerema Urge
- Getacher Lemma
- Getahun Genanew K a
- Getie Molla
- Ghadirian Fataneh
- Ghafarian Sadegh
- Ghaffari Jolfayi Amir
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- Ghazy Ramy Mohamed
- Gholami Ali
- Gholamrezanezhad Ali
- Gholizadeh Nasim
- Ghorbani Mahsa
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- Gil Gabriela Fernanda
- Gilbertson Nora M
- Gill Paramjit Singh
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- Gindaba Ebisa Zerihun
- Girmay Alem
- Glasbey James C
- Gnedovskaya Elena V
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- Goel Amit
- Golechha Mahaveer
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- Golinelli Davide
- Gomes Nelson G M
- Gopalani Sameer Vali
- Gorini Giuseppe
- Goudarzi Houman
- Goulart Alessandra C
- Gouravani Mahdi
- Goyal Anmol
- Göbölös Laszlo
- Graham Simon Matthew
- Grivna Michal
- Grosso Giuseppe
- Guan Shi-Yang
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- Temesgen Worku Animaw
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- Terefa Dufera Rikitu
- Teye-Kwadjo Enoch
- Thakur Ramna
- Thangaraju Pugazhenthan
- Thankappan Kavumpurathu Raman
- Thapar Rekha
- Thayakaran Rasiah
- Thirunavukkarasu Sathish
- Thomas Nihal
- Thomas Nikhil Kenny
- Tian Jing
- Tichopad Ales
- Ticoalu Jansje Henny Vera
- Tiruye Tenaw Yimer
- Tobe-Gai Ruoyan
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- Tonelli Marcello
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- Udoh Arit
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- Vakili Omid
- Valenti Mario
- Valizadeh Rohollah
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- van Donkelaar Aaron
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- Venketasubramanian Narayanaswamy
- Verghese Nicholas Alexander
- Verma Madhur
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- Waheed Yasir
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- Wang Fang
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- Wang Yanzhong
- Wang Yuan-Pang
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- Ye Pengpeng
- Yesodharan Renjulal
- Yesuf Subah Abderehim
- Yezli Saber
- Yi Siyan
- Yigzaw Zeamanuel Anteneh
- Yiğit Arzu
- Yin Dehui
- Yip Paul
- Yismaw Malede Berihun
- Yon Dong Keon
- Yonemoto Naohiro
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- Younis Mustafa Z
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- Yu Chuanhua
- Yu Yong
- Zadey Siddhesh
- Zadnik Vesna
- Zakham Fathiah
- Zaki Nazar
- Zakzuk Josefina
- Zamagni Giulia
- Zaman Sojib Bin
- Zandieh Ghazal G Z
- Zanghì Aurora
- Zar Heather J
- Zare Iman
- Zarimeidani Fatemeh
- Zastrozhin Mikhail Sergeevich
- Zeng Youjie
- Zhai Chunxia
- Zhang Anthony Lin
- Zhang Haijun
- Zhang Liqun
- Zhang Meixin
- Zhang Yunquan
- Zhang Zhenyu
- Zhang Zhi-Jiang
- Zhao Hanqing
- Zhao Jeff T
- Zhao Xiu-Ju George
- Zhao Yang
- Zhao Yong
- Zheng Peng
- Zhong Chenwen
- Zhou Jingjing
- Zhou Juexiao
- Zhou Shangcheng
- Zhu Bin
- Zhu Lei
- Zhu Zhaohua
- Ziaeian Boback
- Ziafati Makan
- Zielińska Magdalena
- Zimsen Stephanie R M
- Zoghi Ghazal
- Zoller Thomas
- Zumla Alimuddin
- Zyoud Sa'ed H
- Zyoud Samer H
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 risk factors in 204 countries and territories and 811 subnational locations, from 1990 to 2021. Methods: The GBD 2021 risk factor analysis used data from 54 561 total distinct sources to produce epidemiological estimates for 88 risk factors and their associated health outcomes for a total of 631 risk–outcome pairs. Pairs were included on the basis of data-driven determination of a risk–outcome association. Age-sex-location-year-specific estimates were generated at global, regional, and national levels. Our approach followed the comparative risk assessment framework predicated on a causal web of hierarchically organised, potentially combinative, modifiable risks. Relative risks (RRs) of a given outcome occurring as a function of risk factor exposure were estimated separately for each risk–outcome pair, and summary exposure values (SEVs), representing risk-weighted exposure prevalence, and theoretical minimum risk exposure levels (TMRELs) were estimated for each risk factor. These estimates were used to calculate the population attributable fraction (PAF; ie, the proportional change in health risk that would occur if exposure to a risk factor were reduced to the TMREL). The product of PAFs and disease burden associated with a given outcome, measured in disability-adjusted life-years (DALYs), yielded measures of attributable burden (ie, the proportion of total disease burden attributable to a particular risk factor or combination of risk factors). Adjustments for mediation were applied to account for relationships involving risk factors that act indirectly on outcomes via intermediate risks. Attributable burden estimates were stratified by Socio-demographic Index (SDI) quintile and presented as counts, age-standardised rates, and rankings. To complement estimates of RR and attributable burden, newly developed burden of proof risk function (BPRF) methods were applied to yield supplementary, conservative interpretations of risk–outcome associations based on the consistency of underlying evidence, accounting for unexplained heterogeneity between input data from different studies. Estimates reported represent the mean value across 500 draws from the estimate's distribution, with 95% uncertainty intervals (UIs) calculated as the 2·5th and 97·5th percentile values across the draws. Findings: Among the specific risk factors analysed for this study, particulate matter air pollution was the leading contributor to the global disease burden in 2021, contributing 8·0% (95% UI 6·7–9·4) of total DALYs, followed by high systolic blood pressure (SBP; 7·8% [6·4–9·2]), smoking (5·7% [4·7–6·8]), low birthweight and short gestation (5·6% [4·8–6·3]), and high fasting plasma glucose (FPG; 5·4% [4·8–6·0]). For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. Age-standardised global DALY rates attributable to high BMI and high FPG rose considerably (15·7% [9·9–21·7] for high BMI and 7·9% [3·3–12·9] for high FPG) over this period, with exposure to these risks increasing annually at rates of 1·8% (1·6–1·9) for high BMI and 1·3% (1·1–1·5) for high FPG. By contrast, the global risk-attributable burden and exposure to many other risk factors declined, notably for risks such as child growth failure and unsafe water source, with age-standardised attributable DALYs decreasing by 71·5% (64·4–78·8) for child growth failure and 66·3% (60·2–72·0) for unsafe water source. We separated risk factors into three groups according to trajectory over time: those with a decreasing attributable burden, due largely to declining risk exposure (eg, diet high in trans-fat and household air pollution) but also to proportionally smaller child and youth populations (eg, child and maternal malnutrition); those for which the burden increased moderately in spite of declining risk exposure, due largely to population ageing (eg, smoking); and those for which the burden increased considerably due to both increasing risk exposure and population ageing (eg, ambient particulate matter air pollution, high BMI, high FPG, and high SBP). Interpretation: Substantial progress has been made in reducing the global disease burden attributable to a range of risk factors, particularly those related to maternal and child health, WaSH, and household air pollution. Maintaining efforts to minimise the impact of these risk factors, especially in low SDI locations, is necessary to sustain progress. Successes in moderating the smoking-related burden by reducing risk exposure highlight the need to advance policies that reduce exposure to other leading risk factors such as ambient particulate matter air pollution and high SBP. Troubling increases in high FPG, high BMI, and other risk factors related to obesity and metabolic syndrome indicate an urgent need to identify and implement interventions
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Abate Yohannes Habtegiorgis
- Abbafati Cristiana
- Abbastabar Hedayat
- Abd ElHafeez Samar
- Abd-Elsalam Sherief
- Abdelmasseh Michael
- Abdollahi Arash
- Abdullahi Auwal
- Abegaz Kedir Hussein
- Abeldaño Zuñiga Roberto Ariel
- Aboagye Richard Gyan
- Abolhassani Hassan
- Abreu Lucas Guimarães
- Abu-Gharbieh Eman
- Abu-Rmeileh Niveen ME
- Abualruz Hasan
- Ackerman Ilana N
- Addo Isaac Yeboah
- Addolorato Giovanni
- Adebiyi Akindele Olupelumi
- Adepoju Abiola Victor
- Adewuyi Habeeb Omoponle
- Afyouni Shadi
- Afzal Saira
- Afzal Sina
- Agodi Antonella
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Firdos
- Ahmad Shahzaib
- Ahmed Ali
- Ahmed Luai A
- Ahmed Muktar Beshir
- Ajami Marjan
- Akinosoglou Karolina
- Akkaif Mohammed Ahmed
- Al Hasan Syed Mahfuz
- Al-Aly Ziyad
- Al-Gheethi Adel Ali Saeed
- Al-Marwani Sabah
- Al-Omari Basem
- Al-Wardat Mohammad Sami
- Al-Worafi Yaser Mohammed
- Alalalmeh Samer O
- Albashtawy Mohammed
- Aldridge Robert W
- Alemu Meseret Desalegn
- Alemu Yihun Mulugeta
- Alene Kefyalew Addis
- Alharrasi Maryam
- Alhassan Robert Kaba
- Ali Mohammed Usman
- Ali Rafat
- Ali Syed Shujait Shujait
- Alif Sheikh Mohammad
- Aljunid Syed Mohamed
- Almazan Joseph Uy
- Alomari Mahmoud A
- Altaany Zaid
- Alvis-Guzman Nelson
- Alvis-Zakzuk Nelson J
- Alwafi Hassan
- Aly Safwat
- Alzoubi Karem H
- Amare Azmeraw T
- Amegbor Prince M
- Ameyaw Edward Kwabena
- Amin Tarek Tawfik
- Amindarolzarbi Alireza
- Amiri Sohrab
- Amugsi Dickson A
- Ancuceanu Robert
- Anderlini Deanna
- Anderson David B
- Andrade Pedro Prata
- Andrei Catalina Liliana
- Ansari Hossein
- Antony Catherine M
- Anwar Saleha
- Anwar Sumadi Lukman
- Anwer Razique
- Anyanwu Philip Emeka
- Arab Juan Pablo
- Arabloo Jalal
- Arafat Mosab
- Araki Daniel T
- Aravkin Aleksandr Y
- Arkew Mesay
- Armocida Benedetta
- Arndt Michael Benjamin
- Arooj Mahwish
- Artamonov Anton A
- Aruleba Raphael Taiwo
- Arumugam Ashokan
- Ashbaugh Charlie
- Ashemo Mubarek Yesse
- Ashraf Muhammad
- Asika Marvellous O
- Askari Elaheh
- Astell-Burt Thomas
- Athari Seyyed Shamsadin
- Atorkey Prince
- Atout Maha Moh'd Wahbi
- Atreya Alok
- Aujayeb Avinash
- Ausloos Marcel
- Avan Abolfazl
- Awotidebe Adedapo Wasiu
- Awuviry-Newton Kofi
- Ayala Quintanilla Beatriz Paulina
- Ayuso-Mateos Jose L
- Azadnajafabad Sina
- Azevedo Rui M S
- Babu Abraham Samuel
- Badar Muhammad
- Badiye Ashish D
- Baghdadi Soroush
- Bagheri Nasser
- Bah Sulaiman
- Bai Ruhai
- Baker Jennifer L
- Bakkannavar Shankar M
- Bako Abdulaziz T
- Balakrishnan Senthilkumar
- Bam Kiran
- Banik Palash Chandra
- Barchitta Martina
- Bardhan Mainak
- Bardideh Erfan
- Barker-Collo Suzanne Lyn
- Barqawi Hiba Jawdat
- Barrow Amadou
- Barteit Sandra
- Barua Lingkan
- Bashiri Aliabadi Somaye
- Basiru Afisu
- Basu Sanjay
- Basu Saurav
- Bathini Prapthi Persis
- Batra Kavita
- Baune Bernhard T
- Bayileyegn Nebiyou Simegnew
- Behnam Babak
- Behnoush Amir Hossein
- Beiranvand Maryam
- Bejarano Ramirez Diana Fernanda
- Bell Michelle L
- Bello Olorunjuwon Omolaja
- Beloukas Apostolos
- Bensenor Isabela M
- Berezvai Zombor
- Bernabe Eduardo
- Bernstein Robert S
- Bettencourt Paulo J G
- Bhagavathula Akshaya Srikanth
- Bhala Neeraj
- Bhandari Dinesh
- Bhargava Ashish
- Bhaskar Sonu
- Bhat Vivek
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- Bhatti Jasvinder Singh
- Bhatti Manpreet S
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- Bisignano Catherine
- Bitra Veera R
- Bjørge Tone
- Bodolica Virginia
- Bodunrin Aadam Olalekan
- Bogale Eyob Ketema
- Bonakdar Hashemi Milad
- Bonny Aime
- Bora Basara Berrak
- Borhany Hamed
- Boxe Christopher
- Brady Oliver J
- Bragazzi Nicola Luigi
- Braithwaite Dejana
- Brant Luisa C
- Brauer Michael
- Breitner Susanne
- Brenner Hermann
- Brown Julie
- Brugha Traolach
- Bulamu Norma B
- Buonsenso Danilo
- Burkart Katrin
- Burns Richard A
- Busse Reinhard
- Bustanji Yasser
- Butt Zahid A
- Byun Justin
- Caetano dos Santos Florentino Luciano
- Calina Daniela
- Campos-Nonato Ismael R
- Cao Chao
- Capodici Angelo
- Carr Sinclair
- Carreras Giulia
- Carugno Andrea
- Carvalho Márcia
- Castaldelli-Maia Joao Mauricio
- Castañeda-Orjuela Carlos A
- Castelpietra Giulio
- Catapano Alberico L
- Cattaruzza Maria Sofia
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- Cámera Luis Alberto
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- Cenderadewi Muthia
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- Chandika Rama Mohan
- Chandrasekar Eeshwar K
- Charalampous Periklis
- Chattu Vijay Kumar
- Chatzimavridou-Grigoriadou Victoria
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- Chimoriya Ritesh
- Ching Patrick R
- Cho William C S
- Choi Sungchul
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- Choudhari Sonali Gajanan
- Chowdhury Rajiv
- Christensen Steffan Wittrup McPhee
- Chu Dinh-Toi
- Chukwu Isaac Sunday
- Chung Eric
- Chung Eunice
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- Claassens Mareli M
- Cogen Rebecca M
- Columbus Alyssa
- Conde Joao
- Cortesi Paolo Angelo
- Cousin Ewerton
- Criqui Michael H
- Cruz-Martins Natália
- D'Oria Mario
- Dadras Omid
- Dai Siyu
- Dai Xiaochen
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- Dalaba Maxwell Ayindenaba
- Damiani Giovanni
- Das Jai K
- Das Saswati
- Dashti Mohsen
- Davletov Kairat
- Dávila-Cervantes Claudio Alberto
- De Leo Diego
- Debele Aklilu Tamire
- Debopadhaya Shayom
- DeCleene Nicole K
- Deeba Farah
- Degenhardt Louisa
- Del Bo' Cristian
- Delgado-Enciso Ivan
- Demetriades Andreas K
- Denova-Gutiérrez Edgar
- Dervenis Nikolaos
- Desai Hardik Dineshbhai
- Desai Rupak
- Deuba Keshab
- Dhama Kuldeep
- Dharmaratne Samath Dhamminda
- Dhingra Sameer
- Dias da Silva Diana
- Diaz Daniel
- Diaz Luis Antonio
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- Dima Adriana
- Ding Delaney D
- Dirac M Ashworth
- do Prado Camila Bruneli
- Do Thao Huynh Phuong
- Dohare Sushil
- Dominguez Regina-Mae Villanueva
- Dong Wanyue
- Dongarwar Deepa
- Dorsey E Ray
- Doshmangir Leila
- Dowou Robert Kokou
- Driscoll Tim Robert
- Dsouza Haneil Larson
- Dsouza Viola
- Dube John
- Dumith Samuel C
- Duncan Bruce B
- Duraes Andre Rodrigues
- Duraisamy Senbagam
- Durojaiye Oyewole Christopher
- Dzianach Paulina Agnieszka
- Dziedzic Arkadiusz Marian
- Eboreime Ejemai
- Ebrahimi Alireza
- Edinur Hisham Atan
- Edvardsson David
- Eikemo Terje Andreas
- Eini Ebrahim
- Ekholuenetale Michael
- Ekundayo Temitope Cyrus
- El Sayed Iman
- El Tantawi Maha
- Elbarazi Iffat
- Elemam Noha Mousaad
- ElGohary Ghada Metwally Tawfik
- Elhadi Muhammed
- Elmeligy Omar Abdelsadek Abdou
- ELNahas Gihan
- Elshaer Mohammed
- Elsohaby Ibrahim
- Engelbert Bain Luchuo
- Erkhembayar Ryenchindorj
- Eshrati Babak
- Estep Kara
- Fabin Natalia
- Fagbamigbe Adeniyi Francis
- Falzone Luca
- Fareed Mohammad
- Farinha Carla Sofia e Sá
- Faris MoezAlIslam Ezzat Mahmoud
- Faro Andre
- Farrokhi Pegah
- Fatehizadeh Ali
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- Ghadiri Keyghobad
- Ghadirian Fataneh
- Ghailan Khalid Yaser
- Ghajar Alireza
- Ghasemi MohammadReza
- Ghasempour Dabaghi Ghazal
- Ghasemzadeh Afsaneh
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- Gholamrezanezhad Ali
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- Gibson Ruth Margaret
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- Ginindza Themba G
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- Goharinezhad Salime
- Goldust Mohamad
- Golechha Mahaveer
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- Gorini Giuseppe
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- Gudeta Mesay Dechasa
- Guha Avirup
- Guicciardi Stefano
- Gulati Snigdha
- Gulisashvili David
- Gunawardane Damitha Asanga
- Guo Cui
- Gupta Anish Kumar
- Gupta Bhawna
- Gupta Ishita
- Gupta Mohak
- Gupta Rajeev
- Gupta Veer Bala
- Gupta Vijai Kumar
- Gupta Vivek Kumar
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- Habibzadeh Farrokh
- Habibzadeh Parham
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- Haep Nils
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- Jahanmehr Nader
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- Jain Nityanand
- Jairoun Ammar Abdulrahman
- Jaiswal Abhishek
- Jakovljevic Mihajlo
- Jatau Abubakar Ibrahim
- Javadov Sabzali
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- Yezli Saber
- Yigzaw Zeamanuel Anteneh
- Yiğit Arzu
- Yiğit Vahit
- Yismaw Yazachew
- Yon Dong Keon
- Yonemoto Naohiro
- Younis Mustafa Z
- Yu Chuanhua
- Yu Yong
- Yusuf Hadiza
- Zahid Mondal Hasan
- Zakham Fathiah
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- Zamora Nelson
- Zand Ramin
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- Zarrintan Armin
- Zastrozhin Mikhail Sergeevich
- Zhang Haijun
- Zhang Ning
- Zhang Yunquan
- Zhao Hanqing
- Zhong Chenwen
- Zhong Panliang
- Zhou Juexiao
- Zhu Zhaohua
- Ziafati Makan
- Zielińska Magdalena
- Zimsen Stephanie R M
- Zoladl Mohammad
- Zumla Alimuddin
- Zyoud Samer H
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to implement strategies that can mitigate diseases. It can also facilitate more rigorous monitoring of progress towards national and international health targets, such as the Sustainable Development Goals. For three decades, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) has filled that need. A global network of collaborators contributed to the production of GBD 2021 by providing, reviewing, and analysing all available data. GBD estimates are updated routinely with additional data and refined analytical methods. GBD 2021 presents, for the first time, estimates of health loss due to the COVID-19 pandemic. Methods: The GBD 2021 disease and injury burden analysis estimated years lived with disability (YLDs), years of life lost (YLLs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries using 100 983 data sources. Data were extracted from vital registration systems, verbal autopsies, censuses, household surveys, disease-specific registries, health service contact data, and other sources. YLDs were calculated by multiplying cause-age-sex-location-year-specific prevalence of sequelae by their respective disability weights, for each disease and injury. YLLs were calculated by multiplying cause-age-sex-location-year-specific deaths by the standard life expectancy at the age that death occurred. DALYs were calculated by summing YLDs and YLLs. HALE estimates were produced using YLDs per capita and age-specific mortality rates by location, age, sex, year, and cause. 95% uncertainty intervals (UIs) were generated for all final estimates as the 2·5th and 97·5th percentiles values of 500 draws. Uncertainty was propagated at each step of the estimation process. Counts and age-standardised rates were calculated globally, for seven super-regions, 21 regions, 204 countries and territories (including 21 countries with subnational locations), and 811 subnational locations, from 1990 to 2021. Here we report data for 2010 to 2021 to highlight trends in disease burden over the past decade and through the first 2 years of the COVID-19 pandemic. Findings: Global DALYs increased from 2·63 billion (95% UI 2·44–2·85) in 2010 to 2·88 billion (2·64–3·15) in 2021 for all causes combined. Much of this increase in the number of DALYs was due to population growth and ageing, as indicated by a decrease in global age-standardised all-cause DALY rates of 14·2% (95% UI 10·7–17·3) between 2010 and 2019. Notably, however, this decrease in rates reversed during the first 2 years of the COVID-19 pandemic, with increases in global age-standardised all-cause DALY rates since 2019 of 4·1% (1·8–6·3) in 2020 and 7·2% (4·7–10·0) in 2021. In 2021, COVID-19 was the leading cause of DALYs globally (212·0 million [198·0–234·5] DALYs), followed by ischaemic heart disease (188·3 million [176·7–198·3]), neonatal disorders (186·3 million [162·3–214·9]), and stroke (160·4 million [148·0–171·7]). However, notable health gains were seen among other leading communicable, maternal, neonatal, and nutritional (CMNN) diseases. Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47·8% (43·3–51·7) and for diarrhoeal diseases decreased by 47·0% (39·9–52·9). Non-communicable diseases contributed 1·73 billion (95% UI 1·54–1·94) DALYs in 2021, with a decrease in age-standardised DALY rates since 2010 of 6·4% (95% UI 3·5–9·5). Between 2010 and 2021, among the 25 leading Level 3 causes, age-standardised DALY rates increased most substantially for anxiety disorders (16·7% [14·0–19·8]), depressive disorders (16·4% [11·9–21·3]), and diabetes (14·0% [10·0–17·4]). Age-standardised DALY rates due to injuries decreased globally by 24·0% (20·7–27·2) between 2010 and 2021, although improvements were not uniform across locations, ages, and sexes. Globally, HALE at birth improved slightly, from 61·3 years (58·6–63·6) in 2010 to 62·2 years (59·4–64·7) in 2021. However, despite this overall increase, HALE decreased by 2·2% (1·6–2·9) between 2019 and 2021. Interpretation: Putting the COVID-19 pandemic in the context of a mutually exclusive and collectively exhaustive list of causes of health loss is crucial to understanding its impact and ensuring that health funding and policy address needs at both local and global levels through cost-effective and evidence-based interventions. A global epidemiological transition remains underway. Our findings suggest that prioritising non-communicable disease prevention and treatment policies, as well as strengthening health systems, continues to be crucially important. The progress on reducing the burden of CMNN diseases must not stall; although global trends are improving, the burden of CMNN diseases remains unacceptably high. Evidence-based interventions will help save the lives of young children and mothers and improve the overall health and economic conditions of societies across the world. Governments and multilateral organisations should prioritise pandemic preparedness planning alongside efforts to reduce the burden of diseases and injuries that will strain resources in the coming decades. Funding: Bill & Melinda Gates Foundation
Search for single production of vector-like quarks decaying into Wb in pp collisions at s=8 TeV with the ATLAS detector
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- Groh Sabrina
- Grohs Johannes P
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- Wanotayaroj Chaowaroj
- Warburton Andreas
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- Waugh Ben
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- Weber Michele
- Weber Stefan Wol
- Webster Jordan S
- Weidberg Anthony
- Weinert Benjamin
- Weingarten Jens
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- Wildauer Andreas
- Wilkens Henric Geo
- Williams Hugh
- Williams Sarah
- Willis Christophe
- Willocq Stephane
- Wilson John
- Wingerter-Seez Isabelle
- Winklmeier Frank
- Winter Benedict T
- Wittgen Matthias
- Wittkowski Josephine
- Wollstadt Simon Jako
- Wolter Marcin Wla
- Wolters Helmut
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- Wotschack Jorg
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- Wu Miles
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- Wynne Benjamin
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- Xu Lailin
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- Yacoob Sahal
- Yakabe Ryota
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- Yamaguchi Yohei
- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
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- Yang Hongtao
- Yang Yi
- Yang Zongchang
- Yao Weiming
- Yap Yee Chinn
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henr
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christophe
- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zakharchuk Nataliia
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zeng Jian Cong
- Zeng Qi
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Rui
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Mingliang
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 08/08/2016
- Field of study
Measurement of the charge asymmetry in top-quark pair production in the lepton-plus-jets final state in pp collision data at s=8TeV with the ATLAS detector
- Author
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Aben Rosemarie
- Abolins Maris
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Agricola Johannes
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Altheimer Andrew Dav
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco
- Arguin Jean-Franc
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron Jame
- Arnaez Olivier
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim Bora
- Augsten Kamil
- Aurousseau Mathieu
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad Ka
- Azuelos Georges
- Baak Max
- Baas Alessandra
- Baca Matthew Jo
- Bacci Cesare
- Bachacou Henri
- Bachas Konstantin
- Backes Moritz
- Backhaus Malte
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Bain Travis
- Baines John
- Baker Oliver Kei
- Baldin Evgenii
- Balek Petr
- Balestri Thomas
- Balli Fabrice
- Balunas William Ke
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
- Barnes Sarah Loui
- Barnett Bruce
- Barnett Michael
- Barnovska Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Barros do Vale Maria Alin
- Bartoldus Rainer
- Barton Adam Edwar
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Basye Austin
- Bates Richard
- Batista Santiago J
- Batley Richard
- Battaglia Marco
- Bauce Matteo
- Bauer Florian
- Bawa Harinder S
- Beacham James Bake
- Beattie Michael Da
- Beau Tristan
- Beauchemin Pierre-Hug
- Beccherle Roberto
- Bechtle Philip
- Beck Hans Peter
- Becker Kathrin
- Becker Maurice
- Beckingham Matthew
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bee Christophe
- Beemster Lars
- Beermann Thomas
- Begel Michael
- Behr Janna Kath
- Belanger-Champagne Camille
- Bell William
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimilia
- Belotskiy Konstantin
- Beltramello Olga
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Bendtz Katarina
- Benekos Nektarios
- Benhammou Yan
- Benhar Noccioli Eleonora
- Benitez Garcia Jorge-Arma
- Benjamin Douglas
- Bensinger James
- Bentvelsen Stan
- Beresford Lydia
- Beretta Matteo
- Berge David
- Bergeaas Kuutmann Elin
- Berger Nicolas
- Berghaus Frank
- Beringer Jürg
- Bernard Clare
- Bernard Nathan Rog
- Bernius Catrin
- Bernlochner Florian Ur
- Berry Tracey
- Berta Peter
- Bertella Claudia
- Bertoli Gabriele
- Bertolucci Federico
- Bertsche Carolyn
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- Clark Allan G
- Clark Brian Lee
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- Edson William
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- Golling Tobias
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- Gornicki Edward
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- Goussiou Anna
- Govender Nicolin
- Gozani Eitan
- Grabas Herve Mari
- Graber Lars
- Grabowska-Bold Iwona
- Gradin Per Olov J
- Grafström Per
- Gramling Johanna
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- Graziani Enrico
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- Grefe Christian
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- Grenier Philippe
- Griffiths Justin
- Grillo Alexander
- Grimm Kathryn
- Grinstein Sebastian
- Gris Philippe L
- Grivaz Jean-Franc
- Grohs Johannes P
- Grohsjean Alexander
- Gross Eilam
- Grosse-Knetter Joern
- Grossi Giulio Cor
- Grout Zara Jane
- Guan Liang
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- Gutierrez Ortiz Nicolas Gi
- Gutierrez Phillip
- Gutschow Christian
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- Haddad Nacim
- Haefner Petra
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- Hakobyan Hrachya
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- Hall David
- Halladjian Garabed
- Hallewell Gregory Da
- Hamacher Klaus
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- Hamnett Phillip Ge
- Han Liang
- Hanagaki Kazunori
- Hanawa Keita
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- Hartjes Fred
- Hasegawa Makoto
- Hasegawa Yoji
- Hasib A
- Hassani Samira
- Haug Sigve
- Hauser Reiner
- Hauswald Lorenz
- Havranek Miroslav
- Hawkes Christophe
- Hawkings Richard Jo
- Hawkins Anthony Da
- Hayashi Takayasu
- Hayden Daniel
- Hays Chris
- Hays Jonathan M
- Hayward Helen
- Haywood Stephen
- Head Simon
- Heck Tobias
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- Henkelmann Steffen
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- Henrot-Versille Sophie
- Herbert Geoffrey H
- Hernández Jiménez Yesenia
- Herten Gregor
- Hertenberger Ralf
- Hervas Luis
- Hesketh Gavin Gran
- Hessey Nigel
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- Higón-Rodriguez Emilio
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- Igonkina Olga
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- Ikematsu Katsumasa
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- Ilchenko Iurii
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- Ince Tayfun
- Introzzi Gianluca
- Ioannou Pavlos
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- Irles Quiles Adrian
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- Istin Serhat
- Iturbe Ponce Julia Mari
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- Jeanty Laura
- Jejelava Juansher
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- Johansson Per
- Johns Kenneth
- Johnson William Jo
- Jon-And Kerstin
- Jones Graham
- Jones Roger
- Jones Tim
- Jongmanns Jan
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- Jussel Patrick
- Juste Rozas Aurelio
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- Kaci Mohammed
- Kaczmarska Anna
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- Kagan Harris
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- Kalderon Charles Wi
- Kama Sami
- Kamenshchikov Andrey
- Kanaya Naoko
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- Kaplan Benjamin
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- Kar Deepak
- Karakostas Konstantin
- Karamaoun Andrew
- Karastathis Nikolaos
- Kareem Mohammad J
- Karentzos Efstathios
- Karnevskiy Mikhail
- Karpov Sergey
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- Kartvelishvili Vakhtang
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- Kasahara Kota
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- Kluit Peter
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- Kneringer Emmerich
- Knoops Edith
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- Weingarten Jens
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- Wildauer Andreas
- Wilkens Henric Geo
- Williams Hugh
- Williams Sarah
- Willis Christophe
- Willocq Stephane
- Wilson Alan
- Wilson John
- Wingerter-Seez Isabelle
- Winklmeier Frank
- Winter Benedict T
- Wittgen Matthias
- Wittkowski Josephine
- Wollstadt Simon Jako
- Wolter Marcin Wla
- Wolters Helmut
- Wosiek Barbara
- Wotschack Jorg
- Woudstra Martin
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- Yacoob Sahal
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- Yamada Miho
- Yamaguchi Daiki
- Yamaguchi Yohei
- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yao Weiming
- Yap Yee Chinn
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henr
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christophe
- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yurkewicz Adam
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zeng Qi
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Guangyi
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Mingliang
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 19/02/2016
- Field of study
ATLAS Run 1 searches for direct pair production of third-generation squarks at the Large Hadron Collider
- Author
- Abbott Brad
- Abdallah Jalal
- Abdinov Ovsat
- Aben Rosemarie
- Abolins Maris
- AbouZeid Ossama
- Abramowicz Halina
- Abreu Henso
- Abreu Ricardo
- Abulaiti Yiming
- Acharya Bobby Sami
- Adamczyk Leszek
- Adams David
- Adelman Jahred
- Adomeit Stefanie
- Adye Tim
- Affolder Tony
- Agatonovic-Jovin Tatjana
- Agricola Johannes
- Aguilar-Saavedra Juan Anton
- Ahlen Steven
- Ahmadov Faig
- Aielli Giulio
- Akerstedt Henrik
- Akimov Andrei
- Alberghi Gian Luigi
- Albert Justin
- Albrand Solveig
- Alconada Verzini Maria Jose
- Aleksa Martin
- Aleksandrov Igor
- Alexa Calin
- Alexander Gideon
- Alexopoulos Theodoros
- Alhroob Muhammad
- Alimonti Gianluca
- Alio Lion
- Alison John
- Alkire Steven Pat
- Allbrooke Benedict
- Allport Phillip
- Aloisio Alberto
- Alonso Alejandro
- Alonso Francisco
- Alpigiani Cristiano
- Altheimer Andrew Dav
- Alvarez Gonzalez Barbara
- Alviggi Mariagrazi
- Amadio Brian Thom
- Amako Katsuya
- Amaral Coutinho Yara
- Amelung Christoph
- Amidei Dante
- Amor Dos Santos Susana Pat
- Amorim Antonio
- Amoroso Simone
- Amram Nir
- Amundsen Glenn
- Anastopoulos Christos
- Ancu Lucian Ste
- Andari Nansi
- Andeen Timothy
- Anders Christoph
- Anders Gabriel
- Anders John Kenne
- Anderson Kelby
- Andreazza Attilio
- Andrei George Vic
- Angelidakis Stylianos
- Angelozzi Ivan
- Anger Philipp
- Angerami Aaron
- Anghinolfi Francis
- Anisenkov Alexey
- Anjos Nuno
- Annovi Alberto
- Antonelli Mario
- Antonov Alexey
- Antos Jaroslav
- Anulli Fabio
- Aoki Masato
- Aperio Bella Ludovica
- Arabidze Giorgi
- Arai Yasuo
- Araque Juan Pedro
- Arce Ayana
- Arduh Francisco
- Arguin Jean-Franc
- Argyropoulos Spyridon
- Arik Metin
- Armbruster Aaron Jame
- Arnaez Olivier
- Arnal Vanessa
- Arnold Hannah
- Arratia Miguel
- Arslan Ozan
- Artamonov Andrei
- Artoni Giacomo
- Asai Shoji
- Asbah Nedaa
- Ashkenazi Adi
- Asquith Lily
- Assamagan Ketevi
- Astalos Robert
- Atkinson Markus
- Atlay Naim Bora
- Auerbach Benjamin
- Augsten Kamil
- Aurousseau Mathieu
- Avolio Giuseppe
- Axen Bradley
- Ayoub Mohamad Ka
- Azuelos Georges
- Baak Max
- Baas Alessandra
- Baca Matthew Jo
- Bacci Cesare
- Bachacou Henri
- Bachas Konstantin
- Backes Moritz
- Backhaus Malte
- Bagiacchi Paolo
- Bagnaia Paolo
- Bai Yu
- Bain Travis
- Baines John
- Baker Oliver Kei
- Baldin Evgenii
- Balek Petr
- Balestri Thomas
- Balli Fabrice
- Banas Elzbieta
- Banerjee Swagato
- Bannoura Arwa A E
- Bansil Hardeep Si
- Barak Liron
- Barberio Elisabetta
- Barberis Dario
- Barbero Marlon
- Barillari Teresa
- Barisonzi Marcello
- Barklow Timothy
- Barlow Nick
- Barnes Sarah Loui
- Barnett Bruce
- Barnett Michael
- Barnovska Zuzana
- Baroncelli Antonio
- Barone Gaetano
- Barr Alan
- Barreiro Guimarães da Costa João
- Barreiro Fernando
- Barros do Vale Maria Alin
- Bartoldus Rainer
- Barton Adam Edwar
- Bartos Pavol
- Basalaev Artem
- Bassalat Ahmed
- Basye Austin
- Bates Richard
- Batista Santiago J
- Batley Richard
- Battaglia Marco
- Bauce Matteo
- Bauer Florian
- Bawa Harinder S
- Beacham James Bake
- Beattie Michael Da
- Beau Tristan
- Beauchemin Pierre-Hug
- Beccherle Roberto
- Bechtle Philip
- Beck Hans Peter
- Becker Kathrin
- Becker Maurice
- Becker Sebastian
- Beckingham Matthew
- Becot Cyril
- Beddall Andrew
- Beddall Ayda
- Bednyakov Vadim
- Bee Christophe
- Beemster Lars
- Beermann Thomas
- Begel Michael
- Behr Janna Kath
- Belanger-Champagne Camille
- Bell William
- Bella Gideon
- Bellagamba Lorenzo
- Bellerive Alain
- Bellomo Massimilia
- Belotskiy Konstantin
- Beltramello Olga
- Benary Odette
- Benchekroun Driss
- Bender Michael
- Bendtz Katarina
- Benekos Nektarios
- Benhammou Yan
- Benhar Noccioli Eleonora
- Benitez Garcia Jorge-Arma
- Benjamin Douglas
- Bensinger James
- Bentvelsen Stan
- Beresford Lydia
- Beretta Matteo
- Berge David
- Bergeaas Kuutmann Elin
- Berger Nicolas
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- Beringer Jürg
- Bernard Clare
- Bernard Nathan Rog
- Bernius Catrin
- Bernlochner Florian Ur
- Berry Tracey
- Berta Peter
- Bertella Claudia
- Bertoli Gabriele
- Bertolucci Federico
- Bertsche Carolyn
- Bertsche David
- Besana Maria Ilar
- Besjes Geert-Jan
- Bessidskaia Bylund Olga
- Bessner Martin Flo
- Besson Nathalie
- Betancourt Christophe
- Bethke Siegfried
- Bevan Adrian Joh
- Bhimji Wahid
- Bianchi Riccardo-M
- Bianchini Louis
- Bianco Michele
- Biebel Otmar
- Biedermann Dustin
- Bieniek Stephen Pa
- Biglietti Michela
- Bilbao De Mendizabal Javier
- Bilokon Halina
- Bindi Marcello
- Binet Sebastien
- Bingul Ahmet
- Bini Cesare
- Biondi Silvia
- Black Curtis
- Black James
- Black Kevin
- Blackburn Daniel
- Blair Robert
- Blanchard Jean-Bapti
- Blanco Jacobo Eze
- Blazek Tomas
- Bloch Ingo
- Blocker Craig
- Blum Walter
- Blumenschein Ulrike
- Bobbink Gerjan
- Bobrovnikov Victor
- Bocchetta Simona Ser
- Bocci Andrea
- Bock Christophe
- Boehler Michael
- Bogaerts Joannes An
- Bogavac Danijela
- Bogdanchikov Alexander
- Bohm Christian
- Boisvert Veronique
- Bold Tomasz
- Boldea Venera
- Boldyrev Alexey
- Bomben Marco
- Bona Marcella
- Boonekamp Maarten
- Borisov Anatoly
- Borissov Guennadi
- Borroni Sara
- Bortfeldt Jonathan
- Bortolotto Valerio
- Bos Kors
- Boscherini Davide
- Bosman Martine
- Boudreau Joseph
- Bouffard Julian
- Bouhova-Thacker Evelina Va
- Boumediene Djamel Edd
- Bourdarios Claire
- Bousson Nicolas
- Boveia Antonio
- Boyd James
- Boyko Igor
- Bozic Ivan
- Bracinik Juraj
- Brandt Andrew
- Brandt Gerhard
- Brandt Oleg
- Bratzler Uwe
- Brau Benjamin
- Brau James
- Braun Helmut
- Brazzale Simone Fed
- Breaden Madden William Dm
- Brendlinger Kurt
- Brennan Amelia Jea
- Brenner Lydia
- Brenner Richard
- Bressler Shikma
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- Bristow Timothy Mi
- Britton Dave
- Britzger Daniel
- Brochu Frederic
- Brock Ian
- Brock Raymond
- Bronner Johanna
- Brooijmans Gustaaf
- Brooks Timothy
- Brooks William
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- Brost Elizabeth
- Brown Jonathan
- Bruckman de Renstrom Pawel
- Bruncko Dusan
- Bruneliere Renaud
- Bruni Alessia
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- Bruschi Marco
- Bruscino Nello
- Bryngemark Lene
- Buanes Trygve
- Buat Quentin
- Buchholz Peter
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- Carminati Leonardo
- Caron Sascha
- Carquin Edson
- Carrillo-Montoya German D
- Carter Janet
- Carvalho João
- Casadei Diego
- Casado Maria Pila
- Casolino Mirkoanton
- Castaneda-Miranda Elizabeth
- Castelli Angelanton
- Castillo Gimenez Victoria
- Castro Nuno Filip
- Catastini Pierluigi
- Catinaccio Andrea
- Catmore James
- Cattai Ariella
- Caudron Julien
- Cavaliere Viviana
- Cavalli Donatella
- Cavalli-Sforza Matteo
- Cavasinni Vincenzo
- Ceradini Filippo
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- Cerrito Lucio
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- Cerv Matevz
- Cervelli Alberto
- Cetin Serkant Al
- Chafaq Aziz
- Chakraborty Dhiman
- Chalupkova Ina
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- Chapman John Derek
- Charlton Dave
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- Cheatham Susan
- Chegwidden Andrew
- Chekanov Sergei
- Chekulaev Sergey
- Chelkov Gueorgui
- Chelstowska Magda Anna
- Chen Chunhui
- Chen Hucheng
- Chen Karen
- Chen Liming
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- Chen Ye
- Cheng Hok Chuen
- Cheng Yangyang
- Cheplakov Alexander
- Cheremushkina Evgenia
- Cherkaoui El Moursli Rajaa
- Chernyatin Valeriy
- Cheu Elliott
- Chevalier Laurent
- Chiarella Vitaliano
- Chiarelli Giorgio
- Childers John Taylo
- Chiodini Gabriele
- Chisholm Andrew
- Chislett Rebecca Th
- Chitan Adrian
- Chizhov Mihail
- Choi Kyungeon
- Chouridou Sofia
- Chow Bonnie Kar
- Christodoulou Valentinos
- Chromek-Burckhart Doris
- Chudoba Jiri
- Chuinard Annabelle
- Chwastowski Janusz
- Chytka Ladislav
- Ciapetti Guido
- Ciftci Abbas Kena
- Cinca Diane
- Cindro Vladimir
- Cioara Irina Anto
- Ciocio Alessandra
- Citron Zvi Hirsh
- Ciubancan Mihai
- Clark Allan G
- Clark Brian Lee
- Clark Philip Jam
- Clarke Robert
- Cleland Bill
- Clement Christophe
- Coadou Yann
- Cobal Marina
- Coccaro Andrea
- Cochran James H
- Coffey Laurel
- Cogan Joshua God
- Colasurdo Luca
- Cole Brian
- Cole Stephen
- Colijn Auke-Piete
- Collot Johann
- Colombo Tommaso
- Compostella Gabriele
- Conde Muiño Patricia
- Coniavitis Elias
- Connell Simon Henr
- Connelly Ian
- Consonni Sofia Mari
- Consorti Valerio
- Constantinescu Serban
- Conta Claudio
- Conti Geraldine
- Conventi Francesco
- Cooke Mark
- Cooper Ben
- Cooper-Sarkar Amanda
- Cornelissen Thijs
- Corradi Massimo
- Corriveau Francois
- Corso-Radu Alina
- Cortes-Gonzalez Arely
- Cortiana Giorgio
- Costa Giuseppe
- Costa María Jos
- Costanzo Davide
- Cottin Giovanna
- Cowan Glen
- Cox Brian
- Cranmer Kyle
- Cree Graham
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- Gris Philippe L
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- Grohs Johannes P
- Grohsjean Alexander
- Gross Eilam
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- Hasegawa Satoshi
- Hasegawa Yoji
- Hasib A
- Hassani Samira
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- Hawkings Richard Jo
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- LeBlanc Matthew Ed
- LeCompte Thomas
- Ledroit-Guillon Fabienne A
- Lee Claire Ale
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- Veatch Jason
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- Vetterli Michel
- Viazlo Oleksandr
- Vichou Irene
- Vickey Boeriu Oana Elena
- Vickey Trevor
- Viehhauser Georg
- Viel Simon
- Vigne Ralph
- Villa Mauro
- Villaplana Perez Miguel
- Vilucchi Elisabetta
- Vincter Manuella
- Vinogradov Vladimir
- Vivarelli Iacopo
- Vives Vaque Francesc
- Vlachos Sotirios
- Vladoiu Dan
- Vlasak Michal
- Vogel Marcelo
- Vokac Petr
- Volpi Guido
- Volpi Matteo
- von der Schmitt Hans
- von Radziewski Holger
- von Toerne Eckhard
- Vorobel Vit
- Vorobev Konstantin
- Vos Marcel
- Voss Rudiger
- Vossebeld Joost
- Vranjes Milosavljevic Marija
- Vranjes Nenad
- Vrba Vaclav
- Vreeswijk Marcel
- Vuillermet Raphael
- Vukotic Ilija
- Vykydal Zdenek
- Wagner Peter
- Wagner Wolfgang
- Wahlberg Hernan
- Wahrmund Sebastian
- Wakabayashi Jun
- Walder James
- Walker Rodney
- Walkowiak Wolfgang
- Wang Chao
- Wang Fuquan
- Wang Haichen
- Wang Hulin
- Wang Jike
- Wang Jin
- Wang Kuhan
- Wang Rui
- Wang Song-Ming
- Wang Tan
- Wang Tingting
- Wang Xiaoxiao
- Wanotayaroj Chaowaroj
- Warburton Andreas
- Ward Patricia
- Wardrope David Robe
- Warsinsky Markus
- Washbrook Andrew
- Wasicki Christoph
- Watkins Peter
- Watson Alan
- Watson Ian
- Watson Miriam
- Watts Gordon
- Watts Stephen
- Waugh Ben
- Webb Samuel
- Weber Michele
- Weber Stefan Wol
- Webster Jordan S
- Weidberg Anthony
- Weinert Benjamin
- Weingarten Jens
- Weiser Christian
- Weits Hartger
- Wells Phillippa
- Wenaus Torre
- Wengler Thorsten
- Wenig Siegfried
- Wermes Norbert
- Werner Matthias
- Werner Per
- Wessels Martin
- Wetter Jeffrey
- Whalen Kathleen
- Wharton Andrew Mar
- White Andrew
- White Martin
- White Ryan
- White Sebastian
- Whiteson Daniel
- Wickens Fred
- Wiedenmann Werner
- Wielers Monika
- Wienemann Peter
- Wiglesworth Craig
- Wiik-Fuchs Liv Antje
- Wildauer Andreas
- Wilkens Henric Geo
- Williams Hugh
- Williams Sarah
- Willis Christophe
- Willocq Stephane
- Wilson Alan
- Wilson John
- Wingerter-Seez Isabelle
- Winklmeier Frank
- Winter Benedict T
- Wittgen Matthias
- Wittkowski Josephine
- Wollstadt Simon Jako
- Wolter Marcin Wla
- Wolters Helmut
- Wosiek Barbara
- Wotschack Jorg
- Woudstra Martin
- Wozniak Krzysztof
- Wu Mengqing
- Wu Miles
- Wu Sau Lan
- Wu Xin
- Wu Yusheng
- Wyatt Terry Rich
- Wynne Benjamin
- Xella Stefania
- Xu Da
- Xu Lailin
- Yabsley Bruce
- Yacoob Sahal
- Yakabe Ryota
- Yamada Miho
- Yamaguchi Yohei
- Yamamoto Akira
- Yamamoto Shimpei
- Yamanaka Takashi
- Yamauchi Katsuya
- Yamazaki Yuji
- Yan Zhen
- Yang Haijun
- Yang Hongtao
- Yang Yi
- Yao Weiming
- Yasu Yoshiji
- Yatsenko Elena
- Yau Wong Kaven Henr
- Ye Jingbo
- Ye Shuwei
- Yeletskikh Ivan
- Yen Andy L
- Yildirim Eda
- Yorita Kohei
- Yoshida Rikutaro
- Yoshihara Keisuke
- Young Charles
- Young Christophe
- Youssef Saul
- Yu David Ren-
- Yu Jaehoon
- Yu Jiaming
- Yu Jie
- Yuan Li
- Yuen Stephanie
- Yurkewicz Adam
- Yusuff Imran
- Zabinski Bartlomiej
- Zaidan Remi
- Zaitsev Alexander
- Zalieckas Justas
- Zaman Aungshuman
- Zambito Stefano
- Zanello Lucia
- Zanzi Daniele
- Zeitnitz Christian
- Zeman Martin
- Zemla Andrzej
- Zengel Keith
- Zenin Oleg
- Zerwas Dirk
- Zhang Dongliang
- Zhang Fangzhou
- Zhang Huijun
- Zhang Jinlong
- Zhang Lei
- Zhang Ruiqi
- Zhang Xueyao
- Zhang Zhiqing
- Zhao Xiandong
- Zhao Yongke
- Zhao Zhengguo
- Zhemchugov Alexey
- Zhong Jiahang
- Zhou Bing
- Zhou Chen
- Zhou Lei
- Zhou Li
- Zhou Ning
- Zhu Cheng Guan
- Zhu Hongbo
- Zhu Junjie
- Zhu Yingchun
- Zhuang Xuai
- Zhukov Konstantin
- Zibell Andre
- Zieminska Daria
- Zimine Nikolai
- Zimmermann Christoph
- Zimmermann Stephanie
- Zinonos Zinonas
- Zinser Markus
- Ziolkowski Michael
- Zobernig Georg
- Zoccoli Antonio
- zur Nedden Martin
- Zurzolo Giovanni
- Zwalinski Lukasz
- Åkesson Torsten Pa
- Åsman Barbro
- Ženiš Tibor
- Živković Lidija
- Άlvarez Piqueras Damián
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 29/10/2015
- Field of study
3-Hydroxyterphenyllin, a natural fungal metabolite, induces apoptosis and S phase arrest in human ovarian carcinoma cells
- Author
- Abe
- Ahn
- Akasaka
- Bakkenist
- Blagosklonny
- Bratton
- Brunelle
- Burma
- Casey Compton
- Chen
- Cheung-Ong
- Cohen
- Ding
- Eastman
- Elaasser
- Evidente
- Fesik
- Fulda
- Galluzzi
- Gary O. Rankin
- Green
- Guan
- Hengartner
- Henkels
- Hennessy
- Holohan
- Jayson
- Joe
- Kobayashi
- Koul
- Lam
- Lee
- Li
- Li
- Liao
- Newman
- Newman
- Nimmanapalli
- Rogalska
- Samuelsen
- Sayers
- Siddiqui
- Siliciano
- Stephen J. Cutler
- Tyagi
- Velkov
- Wang
- Wang
- Williams
- Wolter
- Wu
- Yadav
- Yaomin Wang
- Yen
- Yen
- Yeo
- Yi Charlie Chen
- Yon Rojanasakul
- Youying Tu
- Yu
- Yu
- Yuan
- Zaffaroni
- Zhang
- Zhang
- Zhou
- Zhu
- Publication venue
- 'Spandidos Publications'
- Publication date
- Field of study
Reproducibility of fluorescent expression from engineered biological constructs in E. coli
- Author
- Abdirakhmanova Altynay
- Abtahi Kimia
- Acar Muradýye
- Adams David
- Adrian Julia Anna
- Afzal Remsha
- Agarwal Yash
- Ahsan Fasih M.
- Ainsworth Catherine
- Akan Madina
- Aktas Muhammed Fatih
- Al Azhar Muhammad
- Altintas Ali
- Ananda Cindy Suci
- Ananos Mathilde
- Ang Timothy
- Anlind Nils
- Appletion Evan
- Appleton Evan
- Arkhipenko Alexander
- Arroyo María Fernanda Sánchez
- Aruanno Marion
- Asthana Ruchi
- Athale Chaitanya A.
- Aubert Pauline
- Auty Joss
- Ayukawa Shotaro
- Badge Richard
- Bailly Valentin
- Bajorinaite Barbora
- Bali Anne Pihl
- Barrick Jeffrey
- Basier Clovis
- Bastuzel Irem
- Bauerl Christine
- Baumgartner Lisa
- Beal Jacob
- Bech Rasmus
- Bejvl Jan
- Belkhelfa Sophia
- Bender Julian
- Bendorius Mykolas
- Berenger Noemie
- Bermúdez José Alberto Cristerna
- Bestepe Furkan
- Bird Jasmine
- Birk Marlène Sophie
- Birkholz Nils
- Black Lucas
- Bodinier Romain
- Bodkhe Swapnil
- Boralli Camila Maria S
- Bourdarias Johan
- Bramorski Camila Barbosa
- Brasino Michael
- Braun Stefanie
- Brown Bradley
- Bruchez Marcel
- Buchser William
- Bugaud Olivier
- Burlington Todd
- Busche Rudiger Frederik
- Buss Marjorie
- Cadenas Cinthya
- Calendini Daniel
- Calvet Charles
- Canabal Eduardo J Zardain
- Canas-Duarte Silvia
- Cancino-Bernardi Juliana
- Canedo Eduardo Cepeda
- Cantu Claudia Nallely Alonso
- Cantu Mercedes Alejandra Vazquez
- Cao Longzhi
- Caput Jules
- Carrigan Matthew
- Castañeda José Ernesto Hernández
- Castillo Javier
- Ceja Jesus Gilberto Rodriguez
- Ceney Aidan
- Ceyhan Yasemin
- Ceylan Furkan Sacit
- Chabert Yoann
- Chahibi Youssef
- Chambonnier Gael
- Chapet-Batlle Alma
- Chapman Elliott
- Chen An
- Chen Jeffrey
- Chen Jielin
- Chen Yahong
- Chen Yintong
- Chen Zehua
- Chen Zhiqin
- Cherrier Floriane
- Chizzolini Fabio
- Choi Peter
- Choukour Myriam
- Christensen Dallin
- Chu Pan
- Ciesla Anthony
- Cigdem Sadik
- Cigdem Sadýk
- Claassens Nico
- Colloms Sean
- Colls Joshua
- Cook Alexander
- Cordova Cesar Miguel Valdez
- Cottignie Ines
- Craig Sean Ross
- Crawford Liam
- Cruz Ángel Farid Rojas
- Cryan Elli
- Cuillery Emilie
- Czerwinska Urszula
- Dalgleish Raymond
- Davies Sian
- De Bruin Yeshi
- De Ferrante Hans
- De Gaulejac Ella
- De Koster Walter
- De La Paz Espinosa Jose Alberto
- De Lima Ana Laura
- De Mora Kim
- De Vries Andries
- De Wijs Freek
- Del Bianco Cristina
- Demarta-Gatsi Claudia
- Demling Philipp
- Demon-Chaine Coralie
- Deng Changyuan
- Densmore Douglas
- Deprez Eline
- Deryckere Astrid
- DeSanty Kayla
- Devlin Tyler Dae
- Dohan Mikail
- Donauer Julia
- Donovan Michael
- Dowell Robin
- Egholm Anne
- Elbert Rick
- Elitok Mustafa
- Elschot Elles
- Elviantari Adelia
- Emig Ramona
- Esmurria Ariela
- Evans Amy
- Fan Zhao
- Fang Baishan
- Fang Beibei
- Fang Yuxing
- Farny Natalie
- Figueroa María Fernanda Salazar
- Fitriana Maya
- Flynn Charlotte
- Fomitcheva Anna
- Franz Matthias
- Friberg Martin
- Fu Xiaotong
- Fujishima Kosuke
- Gabryelczyk Bartosz
- Gakhare Harsh
- Gamez Eddie Cano
- Gangan Manasi
- Garcia Carlos Enrique Alavez
- Georgiev Daniel
- Gerngross Daniel
- Gershater Markus
- Gertsch Sara
- Giraldo-Perez Daniel
- Glaister Graeme
- Godino Elisa
- Golino Caroline
- Gomez-Garzon Camilo
- Gopaul Deshmukh
- Goss Dan
- Greenberg Danny
- Grundy Cameron
- Gugger Muriel
- Gullberg Erik
- Gunadhi Vivienne
- Gunduz Esra
- Gunduz Mehmet
- Guo Xifeng
- Gursel Mayda
- Gutierrez Alejandro
- Gutierrez Alex
- Gutiérrez Carlos Ramos
- Gómez Daniela Flores
- Haddock-Angelli Traci
- Hakstol Rhys
- Halleran Andrew
- Han Ju Yeon
- Hand Robert
- Hanke Rene
- Hansen Anders Chr
- Hansen Anne Sofie Laerke
- Hanzel Martin
- Hasegawa Takema
- Hatin Isabelle
- Hatipoglu Omer Faruk
- Hawthorne Dakota
- Heng Joseph
- Heredia Ana Laura Navarro
- Herman Stephanie
- Hernandez Adriana
- Hernandez Jesus Eduardo Martinez
- Hernandez Mario Alberto Pena
- Herring Daniel
- Hielkema Lisa
- Ho Jack
- Hollenhorst Jim
- Hoover Benjamin
- Hou Qingfeng
- Houy Camille
- Hua Shuyu
- Huang Tianyi
- Huerta Ana Laura Torres
- Huet-Trujillo Estefania
- Hull Raphaella
- Ikonen Martina
- Iniesta Jorge Sebastián Rodríguez
- Isaacs Farren
- Jackowski Marta Eva
- Jacobs Laura
- Jacobs Taylor
- Jacquot Vincent
- Jacry Cecile
- Jagadeesan Chandhuru
- Jagger Verena
- Janssens Jasper
- Jauregui Sebastian Valdivieso
- Jawale Yash
- Jayawardhana Bayu
- Jensen Kristian
- Jesser Rabea
- Jiang Yue
- Jianguo He
- Jin Yuji
- Jing Zhang
- Jonnaert Frederik
- Ju Tina
- Kadam Snehal
- Kaid-Slimane Ibtissam
- Kang Seong Koo
- Karia Payal
- Karlsen Kristian Barreth
- Kashiwagi Takahiro
- Kasl Hynek
- Kaya Turan
- Kelly Ciaran
- Kent Ryan
- Kerns Timothy
- Khetan Neha
- Kiga Daisuke
- Kizil Burak
- Knoerlein Anna
- Kong Wei Chung
- Konzock Oliver
- Koutsoubelis Nicolas
- Kozakai Tomoya
- Krauss Lucas
- Kronborg Tina
- Kruczko Charlie
- Kuipers Oscar
- Kumru Ilkem
- Kunin Daniel
- Kuvvet Yasemin
- Kyriakakis Phillip
- Lai Dengwen
- LaJeunesse Chloe
- Lale Rahmi
- Lambert Caroline
- Lau Effie
- Lau Kenneth
- Lauxen Anna
- Le Doujet Typhaine
- Lee Donna
- Lee Jenny
- Lee Stephen
- LeFew Michael
- Lei Yiying
- Lentini Roberta
- Levier Axel
- Lewis Kathleen
- Leyva-Hernandez Ariel
- Li Cheng
- Li Jianqiao
- Li Jun
- Li Pai
- Li Xiangkai
- Li Yumeng
- Li Zhe
- Lian Sharon
- Liang Jinyang
- Lieberman Erica
- Lins Paula Maria Pincela
- Lippold Steffen
- Liu Chang
- Liu Jianheng
- Liu Weibing
- Liu Yang
- Lizarazo Meagan
- Loechner Anne C.
- Logger Loreen
- Loke Chun Mun
- Lomeikaite Vilija
- Lona Alonso Pérez
- Lopez Lucia T Estelles
- Lu Li Chieh
- Ludwig Carsten
- Lv Yizhu
- Ma Natalie
- Ma Yu
- Madrid-Wolff Jorge
- Malczewska Katarzyna
- Malone Brandon
- Malsot Paola
- Maniaci Joe
- Mansy Sheref S.
- Mao Stephanie
- Marin-Medina Nathaly
- Marken John
- Marles-Wright Jon
- Marsden Stefan
- Martin Noel Yeh
- Maruyama Haruka
- Matabishi-Bibi Laura
- Mate Seme
- Maxfield Cody
- Mazza Julie
- Mazzanti Valentina
- McCutcheon Griffin
- Meier Michael
- Meijer Thomas
- Meli Rocco
- Mellentine Sam
- Melo Cristiane Casonato
- Mendonca Deborah Cezar
- Meng Xinyu
- Michel Anja
- Miinalainen Tuukka
- Miller Charles
- Miller Dylan
- Minegishi Misa
- Mirzarafie-Ahi Ariana
- Mishler Dennis
- Mishra Yash
- Moatti Audrey
- Moghe Prachiti
- Mohand-Said Sarah
- Monk Jordan
- Montesinos Oliva Angélica Sánchez
- Montiel Eduardo Ramirez
- Morales Eduardo Serna
- Morales Yamile Minerva Castellanos
- Moran Barry
- Moreira Barbara Castro
- Mortensen Kate
- Mosbech Caroline
- Mosqueiro Thiago
- Mous Sandra
- Moynihan Vicky
- Mucha Marlena
- Muller Jan Willem
- Mundhe Gayatri
- Mundt Max
- Naidu Yamini
- Navarro Diana Clarisse Montaño
- Ndiaye Cheikh Fall
- Neumann Julika
- Nguyen Thai
- Ni Chunyang
- Nielsen Chad
- Nin Sebastien
- Ning Kang
- Niyazmetova Luiza
- Nooijens Sjoerd
- O'Hara Samantha
- Olivares Fernanda Sotomayor
- Ono Bruno
- Orakov Askarbek
- Orozco Edgar Alberto Alcalá
- Ospovat Ophir
- Osthege Michael
- Otero Karin
- Owen Liusaidh
- Pacheco Alan
- Paino Ieda Maria Martinez
- Pak Thomas
- Parris Elliott
- Parutto Pierre
- Paskett Michael
- Patil Abha
- Pechotova Katerina
- Peebles Christie
- Pegorar Claudio Oss
- Pei Wan
- Pelisek Vaclav
- Pena Omar Alonso Cantu
- Perez Enrique Amaya
- Peters Danielle
- Petrauskas Arnas
- Pettersen Jens S.
- Phadke Ira
- Philippi Melanie
- Platz Lukas
- Pogoda Cloe Simone
- Poondla Revanth
- Popp Philipp
- Post Michelle
- Prima Valerie
- Priracha Shaheer
- Prout Luba
- Provan James
- Pulver Cyril
- Putman Ryan
- Pérezávila Juana Yessica
- Qin Qikai
- Quinton Duke
- Radeck Jara
- Ramirez Carlos Alejandro Meza
- Ramirez Rebeca Paola Torres
- Ramirez-Rodríguez Eduardo A.
- Rauluseviciute Ieva
- Raza Sikandar
- Reddy Sanjana
- Rettberg Randy
- Ribovski Lais
- Richter Alexandra
- Richter Felix
- Rifei Chen
- Robben Johan
- Rocha J. Claudio Moreno
- Rocha Tyler
- Rodenburg Anne
- Rodriguez-Forero Laura
- Roee Marit Vaagen
- Rong Wang
- Rostain William
- Rothschild Lynn
- Rothschild-Mancinelli Brooke
- Ruan Qingyu
- Ryan Kate
- Sabath Kevin
- Saha Margaret
- Salmela Minnamari
- Salvador Nick
- Sanchez Alber
- Sanguesa Hector
- Saraf Aakanksha
- Sarfatis Ari
- Satyadi Megan A.
- Savickyte Ieva
- Sawar Shihab
- Sayin Orhan
- Schauer Oliver
- Schechtel Anna
- Schepers Otto
- Scher Eitan
- Schulte Natalie
- Sebastian Mariola
- Shattuck Kendra
- Shaykevich Daniel
- Shi Yuanjie
- Shih Joseph D.
- Shilts Jarrod
- Shin Nathan
- Shinohara Riku
- Sigismund Christian
- Silva Everton
- Silva Ivan
- Silva Juan Carlos Rueda
- Siriwardena Dylan
- Slack Joseph
- Smith Dustin
- Smith Olivia
- Smits Oscar
- Sommer Anna
- Song Xinhao
- Sosnova Anna
- Spencer-Milnes Xenia
- Sporbeck Katharina
- Steijl Barbara
- Steiner Loic
- Steininger Victor
- Stuhn Lara
- Sturgis James N.
- Su Yetian
- Su Yue
- Sudarsan Suresh
- Sun Libo
- Takahashi Jack
- Tang Chun
- Tang Shuyan
- Tangirala Sivateja
- Tapan Safa
- Teague Brian
- Telmer Cheryl
- Tercan Helin
- Tereci Osman Faruk
- Thavarajah Walter
- Thirukkumaran Ovia Margaret
- Thompson Kirsten
- Thouvenin Gregoire
- Timmons Joshua
- Tingley Jeff
- Tokuma Hiraku
- Torgesen Alexander
- Tran Forrest
- Trejo Elizabeth Vallejo
- Tumas Sarunas
- Turland Alex
- Tye Chelsey
- Tzahristos Alex
- Uniyal Prashant
- Uran Axel
- Urick David
- Uçar Abdullah
- Vaassen Femke
- Van Der Does Marit
- Van Der Putten Cas
- Van Deuren Vincent
- Van Hese Laura
- Van Leeuwen Esther
- Van Raaphorst Renske
- Van Rijn Erwin
- Van Rosmalen Rik
- Van Smeden Laura
- Van Tiel Nina
- Van Wonterghem Laetitia
- Van't Hof Max
- Vandebroek Laurens
- Vandendaele Amelie
- Vasconcelos Graziele
- Vazquez Claudia Melissa Guerra
- Veening Jan Willem
- Verschooten Leen
- Vij Panya
- Vilar Marta Vazquez
- Viola John
- Von Chamier Lucas
- Von Kügelgen Nicolai
- Wadhams George
- Wahab Adam
- Walsh Kevin
- Wang Boxiang
- Wang Haotian
- Wang Lena
- Wang Weiyi
- Wang Xuan
- Wang Yingqi
- Wang Yushen
- Watkins Ella
- Weber Susanne
- Wehle Devin
- Wehrs Maren
- Wei Huang
- Wei Yang
- Wei Yibing
- Wellinger Lisa
- Wellman Rachel
- Weme Ruud Detert Oude
- Werchau Niels
- Westwood Georgina
- Wieden Hans Joachim
- Wieske Lianne
- Witarto Arief Budi
- Wojcik Emilia
- Wolter Moritz
- Wronska Anna
- Wu Fan
- Wu Guozhao
- Wu Qi
- Wu Wen Ying
- Xiang Daniel
- Xiangyue Hu
- Xiaojing Li
- Xiaomei Lin
- Xiaoran Yang
- Xu Zixuan
- Xunxun Luo
- Yamazaki Yuta
- Yan Jieyu
- Yan Keji
- Yan Ming
- Yan Xiaoshan
- Yang Kang
- Yang Yang
- Yang Yunjun
- Yao Ningning
- Yasunishi Shuhei
- Yen Zen Zen
- Yilmaz Mustafa
- Ying Oscar
- Young Hannah
- Young Paul
- Yousaf Waqar
- Yu Michelle
- Yuanzhan Yang
- Yuksel Seniz
- Yulianti
- Yushan Zhang
- Zach Pavel
- Zadey Siddhesh
- Zampronio Danilo Keiji
- Zaworski Julie
- Zeng Zhi
- Zhailauova Azhar
- Zhan Yi
- Zhang Haoqian Myelin
- Zhang Qianbin
- Zhang Ruihua
- Zhang Tangduo
- Zhang Zhaoran
- Zhao Hongxia
- Zhao Ruixue
- Zhaosen Wen
- Zhou Yineng
- Zhu Iowis
- Zhu Kwan Kwan
- Zimmermann Arne
- Zimont Allison
- Zixuan Erinn Sim
- Ávila Alejandro Gómez
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/03/2016
- Field of study
We present results of the first large-scale interlaboratory study carried out in synthetic biology, as part of the 2014 and 2015 International Genetically Engineered Machine (iGEM) competitions. Participants at 88 institutions around the world measured fluorescence from three engineered constitutive constructs in E. coli. Few participants were able to measure absolute fluorescence, so data was analyzed in terms of ratios. Precision was strongly related to fluorescent strength, ranging from 1.54-fold standard deviation for the ratio between strong promoters to 5.75-fold for the ratio between the strongest and weakest promoter, and while host strain did not affect expression ratios, choice of instrument did. This result shows that high quantitative precision and reproducibility of results is possible, while at the same time indicating areas needing improved laboratory practices.Peer reviewe