PELATIHAN DIGITALISASI PRODUK UMKM SEBAGAI MEDIA UNTUK MENINGKATKAN SOFT SKILL DAN BRAND AWARENESS BAGI PEMILIK UMKM DI DESA PONGANGAN KECAMATAN MANYAR

Desa pongangan yang terletak di wilayah kecamatan manyar kabupaten gresik lokasi dari desa pongangan berada di sebelah utara berbatasan dengan kecamatan bungah di sebelah timur berbatasan dengan kecamatan gresik dan selat Madura, di sebalah selatan berbatasan dengan kecamatan kebomas, di sebelah barat berbatasan dengan kecamatan duduk sampeyan. kegiatan sosialisasi yang diberikan oleh mahasiswa Universitas Muhammadiyah Gresik bagi masyarakat desa pongangan dengan meningkatkan soft skill dan brand awareness bagi pemilik UMKM, sehingga masyarakat yang berpartisipasi mendapatkan manfaat terhadap sosialisasi yang telah diadakan

Coulomb Interactions between Cytoplasmic Electric Fields and Phosphorylated Messenger Proteins Optimize Information Flow in Cells

Normal cell function requires timely and accurate transmission of information from receptors on the cell membrane (CM) to the nucleus. Movement of messenger proteins in the cytoplasm is thought to be dependent on random walk. However, Brownian motion will disperse messenger proteins throughout the cytosol resulting in slow and highly variable transit times. We propose that a critical component of information transfer is an intracellular electric field generated by distribution of charge on the nuclear membrane (NM). While the latter has been demonstrated experimentally for decades, the role of the consequent electric field has been assumed to be minimal due to a Debye length of about 1 nanometer that results from screening by intracellular Cl- and K+. We propose inclusion of these inorganic ions in the Debye-Huckel equation is incorrect because nuclear pores allow transit through the membrane at a rate far faster than the time to thermodynamic equilibrium. In our model, only the charged, mobile messenger proteins contribute to the Debye length.Using this revised model and published data, we estimate the NM possesses a Debye-Huckel length of a few microns and find this is consistent with recent measurement using intracellular nano-voltmeters. We demonstrate the field will accelerate isolated messenger proteins toward the nucleus through Coulomb interactions with negative charges added by phosphorylation. We calculate transit times as short as 0.01 sec. When large numbers of phosphorylated messenger proteins are generated by increasing concentrations of extracellular ligands, we demonstrate they generate a self-screening environment that regionally attenuates the cytoplasmic field, slowing movement but permitting greater cross talk among pathways. Preliminary experimental results with phosphorylated RAF are consistent with model predictions.This work demonstrates that previously unrecognized Coulomb interactions between phosphorylated messenger proteins and intracellular electric fields will optimize information transfer from the CM to the NM in cells

EVALUASI PENERAPAN E-COMMERCE PADA PERUSAHAAN DISTRIBUTOR PT. PANAHMAS DWITAMA DISTRINDO JEMBER

The digital era has caused people's shopping patterns to change from offline to online. Many companies are competing to establish e-commerce to meet the ever-increasing online market. PT. Panahmas Dwitama Distrindo Jember is a manufacturing product distribution company PT Unilever Indonesia which dominates the market in Jember and its surroundings, and has also implemented an e-commerce called Panahmas Warung since 2020. This descriptive qualitative research method aims to evaluate how the application of e-commerce supports the success of Panahmas marketing in developing the market. As a result, Panahmas Warung was not managed seriously, so it ran static, and the application was discontinued in 2022. The reason for stopping the Panahmas Warung application was allegedly due to its inability to develop the company's market or business. There are many causes for Panahmas Warung's failure such as lack of human resources, lack of user interest, lack of promos, lack of collaboration and lack of social media utilization because the managing human resources are not adaptive to the latest technology. From the results of the research above, it can be concluded that as a consumer goods distributor company, PT Panahmas Dwitama Distrindo has quite a big opportunity in developing its business. This can be achieved if PT Panahmas Dwitama Distrindo utilizes online or e-commerce application channels in the form of a website or the company's official social media accounts which are managed professionally and consistently

EVALUASI PENERAPAN E-COMMERCE PADA PERUSAHAAN DISTRIBUTOR PT PANAHMAS DWITAMA DISTRINDO JEMBER

The digital era has caused people's shopping patterns to change from offline to online. Many companies are competing to establish e-commerce to meet the ever-increasing online market. PT. Panahmas Dwitama Distrindo Jember is a manufacturing product distribution company PT Unilever Indonesia which dominates the market in Jember and its surroundings, and has also implemented an e-commerce called Panahmas Warung since 2020. This descriptive qualitative research method aims to evaluate how the application of e-commerce supports the success of Panahmas marketing in developing the market. As a result, Panahmas Warung was not managed seriously, so it ran static, and the application was discontinued in 2022. The reason for stopping the Panahmas Warung application was allegedly due to its inability to develop the company's market or business. There are many causes for Panahmas Warung's failure such as lack of human resources, lack of user interest, lack of promos, lack of collaboration and lack of social media utilization because the managing human resources are not adaptive to the latest technology. From the results of the research above, it can be concluded that as a consumer goods distributor company, PT Panahmas Dwitama Distrindo has quite a big opportunity in developing its business. This can be achieved if PT Panahmas Dwitama Distrindo utilizes online or e-commerce application channels in the form of a website or the company's official social media accounts which are managed professionally and consistently.The digital era has caused people's shopping patterns to change from offline to online. Many companies are competing to establish e-commerce to meet the ever-increasing online market. PT. Panahmas Dwitama Distrindo Jember is a manufacturing product distribution company PT Unilever Indonesia which dominates the market in Jember and its surroundings, and has also implemented an e-commerce called Panahmas Warung since 2020. This descriptive qualitative research method aims to evaluate how the application of e-commerce supports the success of Panahmas marketing in developing the market. As a result, Panahmas Warung was not managed seriously, so it ran static, and the application was discontinued in 2022. The reason for stopping the Panahmas Warung application was allegedly due to its inability to develop the company's market or business. There are many causes for Panahmas Warung's failure such as lack of human resources, lack of user interest, lack of promos, lack of collaboration and lack of social media utilization because the managing human resources are not adaptive to the latest technology. From the results of the research above, it can be concluded that as a consumer goods distributor company, PT Panahmas Dwitama Distrindo has quite a big opportunity in developing its business. This can be achieved if PT Panahmas Dwitama Distrindo utilizes online or e-commerce application channels in the form of a website or the company's official social media accounts which are managed professionally and consistently

Weighted connected k-domination and weighted

k-dominatingclique in distance-hereditary graphs