30 research outputs found

    Lymphome t/nk primitif du larynx : localisation inhabituelle de lymphome extranodal

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    Nous rapportons un cas de lymphome extranodal T/Nk primitif du larynx. il s’agit d’un patient ĂągĂ© de 22 ans qui s’était prĂ©sentĂ© pour une dysphonie chronique associĂ©e Ă  une dyspnĂ©e inspiratoire. une chimiothĂ©rapie protocole SMiLE avec radiothĂ©rapie ont Ă©tĂ© instituĂ©s avec obtention d’une rĂ©mission complĂšte. Huit mois plus tard, le patient prĂ©sentait une rĂ©cidive de la tumeur avec un oedĂšme palpĂ©bral et une obstruction du canal lacrymonasal. L’évolution a Ă©tĂ© fatale suite Ă  une aspergillose invasive en cours de chimiothĂ©rapie.Mots clĂ©s : lymphome, larynx.A rare case of primary laryngeal T/Nk- cell lymphoma, nasal type is reported. The patient was 22-year old male who presented with dysphonia, dyspnea. Chemotherapy protocol SMiLE and radiotherapy were instituted with complete remission of the tumor. Eight months afterward, he presented with tumor recurrence, palpebral edema, obstruction of the lacrymonasal duct. He died within few days with invasive aspergillosis while he was receiving chemotherapy SMiLE regimen.Keyswords : lymphoma, larynx

    IKZF1 genetic variants rs4132601 and rs11978267 and acute lymphoblastic leukemia risk in Tunisian children: a casecontrol study

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    Background Associations between IKZF1 gene variants and Acute Lymphoblastic Leukemia (ALL) was recently reported. We examined whether the common IKZF1 polymorphisms rs4132601 T/G and rs111978267 A/G are associated with ALL among a Tunisian pediatric cohort. Methods This case-control study involved 170 patients with ALL and 150 control subjects. SNP genotyping was performed by TaqManÂź SNP Genotyping Assay
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