Internal model controller based PID with fractional filter design for a nonlinear process

In this paper, an Internal model Controller (IMC) based PID with fractional filter for a first order plus time delay process is proposed. The structure of the controller has two parts, one is integer PID controller part cascaded with fractional filter. The proposed controller has two tuning factors λ, filter time constant and a, fractional order of the filter. In this work, the two factors are decided in order to obtain low Integral Time Absolute Error (ITAE). The effectiveness of the proposed controller is studied by considering a non linear (hopper tank) process. The experimental set up is fabricated in the laboratory and then data driven model is developed from the experimental data. The non linear process model is linearised using piecewise linearization and two linear regions are obtained. At each operating point, linear first order plus dead time model is obtained and the controller is designed for the same. To show the practical applicability, the proposed controller is implemented for the proposed experimental laboratory prototype

Federated learning enables big data for rare cancer boundary detection.

Although machine learning (ML) has shown promise across disciplines, out-of-sample generalizability is concerning. This is currently addressed by sharing multi-site data, but such centralization is challenging/infeasible to scale due to various limitations. Federated ML (FL) provides an alternative paradigm for accurate and generalizable ML, by only sharing numerical model updates. Here we present the largest FL study to-date, involving data from 71 sites across 6 continents, to generate an automatic tumor boundary detector for the rare disease of glioblastoma, reporting the largest such dataset in the literature (n = 6, 314). We demonstrate a 33% delineation improvement for the surgically targetable tumor, and 23% for the complete tumor extent, over a publicly trained model. We anticipate our study to: 1) enable more healthcare studies informed by large diverse data, ensuring meaningful results for rare diseases and underrepresented populations, 2) facilitate further analyses for glioblastoma by releasing our consensus model, and 3) demonstrate the FL effectiveness at such scale and task-complexity as a paradigm shift for multi-site collaborations, alleviating the need for data-sharing

Author Correction: Federated learning enables big data for rare cancer boundary detection.

10.1038/s41467-023-36188-7NATURE COMMUNICATIONS14

Federated Learning Enables Big Data for Rare Cancer Boundary Detection

Although machine learning (ML) has shown promise across disciplines, out-of-sample generalizability is concerning. This is currently addressed by sharing multi-site data, but such centralization is challenging/infeasible to scale due to various limitations. Federated ML (FL) provides an alternative paradigm for accurate and generalizable ML, by only sharing numerical model updates. Here we present the largest FL study to-date, involving data from 71 sites across 6 continents, to generate an automatic tumor boundary detector for the rare disease of glioblastoma, reporting the largest such dataset in the literature (n = 6, 314). We demonstrate a 33% delineation improvement for the surgically targetable tumor, and 23% for the complete tumor extent, over a publicly trained model. We anticipate our study to: 1) enable more healthcare studies informed by large diverse data, ensuring meaningful results for rare diseases and underrepresented populations, 2) facilitate further analyses for glioblastoma by releasing our consensus model, and 3) demonstrate the FL effectiveness at such scale and task-complexity as a paradigm shift for multi-site collaborations, alleviating the need for data-sharing

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

The development of a generalized multilevel inverter for symmetrical and asymmetrical dc sources with a minimized ON state switch

This paper proposes a double source double diode double switch (DSDDDS) multilevel inverter to generate positive voltage and a connecting polarity changing circuit of an H-bridge inverter to generate negative voltage. By connecting the jth number of basic units in series, the desired level is obtained. Various algorithms, such as Natural, Binary, Trinary, and Quasi-Linear sequences, and two proposed algorithms are discussed to determine the magnitude of DC voltage sources in order to generate more stepped levels with fewer switches. The proposed multilevel inverter eliminates the need to turn on additional power switches for different levels, which is the main advantages of this topology. The proposed multilevel inverter is compared to conventional switched diode multilevel inverters in terms of switch count, number of ON state switches per level, driver circuits, and total standing voltage. Real-time results from the OPAL-RT test bench and simulation have validated the proposed inverter