Bioceramic Cements in Endodontics

New bioceramic calcium silicate endodontic cements have been recently introduced in the market. They are biocompatible materials that stimulate mineralization. Its dimensional stability is similar to the Fillapex MTA with greater thickness and solubility than AH Plus (Dentsply, DeTrey, Konstanz, Germany) as it is water based. Stored in dispensed syringe, it has a pre-mixed consistency. They are used with the single cone obturation technique because they have properties that are changed when heated. They were developed by inducing bioactivity on the surface of the material when in contact with tissue fluids. An improvement in the osteoblastic differentiation of the cells of the periodontal ligament, induction of remineralization of the dentin, and excellent antimicrobial properties have also been associated with these cements. These properties make these cements an excellent alternative in the attempt to obtain a three-dimensional obturation of the Root Canal System (SCR)

Association of 3-Phenoxybenzoic Acid Exposure during Pregnancy with Maternal Outcomes and Newborn Anthropometric Measures: Results from the IoMum Cohort Study

The aims of this study were to characterize the exposure of pregnant women living in Portugal to 3-phenoxybenzoic acid (3-PBA) and to evaluate the association of this exposure with maternal outcomes and newborn anthropometric measures. We also aimed to compare exposure in summer with exposure in winter. Pregnant women attending ultrasound scans from April 2018 to April 2019 at a central hospital in Porto, Portugal, were invited to participate. Inclusion criteria were: gestational week between 10 and 13, confirmed fetal vitality, and a signature of informed consent. 3-PBA was measured in spot urine samples by gas chromatography with mass spectrometry (GC-MS). The median 3-PBA concentration was 0.263 (0.167; 0.458) μg/g creatinine (n = 145). 3-PBA excretion was negatively associated with maternal pre-pregnancy body mass index (BMI) (p = 0.049), and it was higher during the summer when compared to winter (p < 0.001). The frequency of fish or yogurt consumption was associated positively with 3-PBA excretion, particularly during the winter (p = 0.002 and p = 0.015, respectively), when environmental exposure is low. Moreover, 3-PBA was associated with levothyroxine use (p = 0.01), a proxy for hypothyroidism, which could be due to a putative 3-PBA—thyroid hormone antagonistic effect. 3-PBA levels were not associated with the anthropometric measures of the newborn. In conclusion, pregnant women living in Portugal are exposed to 3-PBA, particularly during summer, and this exposure may be associated with maternal clinical features.This article was supported by national funds through the FCT Foundation for Science and Technology, I.P., within the scope of the projects RISE - LA/P/0053/2020; CINTESIS, R&D UNIT (reference UIDB/4255/2020) and LAQV (references: UIDB/50006/2020 AND UIDP/50006/2020). Virgínia Cruz Fernandes was funded by FCT/MCTES (Foundation for Science and Technology and Ministry of Science, Technology and Higher Education) and the ESF (European Social Fund) through NORTE 2020 (North Region Operational Program) through a grant of Post-Doc (reference SFRH/BPD/109153/2015). Juliana Guimarães was funded by FCT/MCTES (Foundation for Science and Technology and Ministry of Science, Technology and Higher Education) under CINTESIS by a PhD scholarship (reference UI/BD/152087/2021). The authors would like to thank the kind participation of all pregnant women and the support of the recruitment activities by the health professionals of the Department of Obstetrics, Centro Hospitalar Universitário S. João, Porto, Portugal and also to the professionals of REQUIMTE/LAQV, Instituto Superior de Engenharia, Politécnico do Porto, for their collaboration in carrying out the analyzes of the 3-PBA metabolite. This work received support from PT national funds (FCT/MCTES, Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) through the projects LA/P/0053/2020; UIDB/4255/2020; UIDB/5006/2020 and UIDP/50006/2020. Virgínia Cruz Fernandes thanks FCT/MCTES (Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) and ESF (European Social Fund) through NORTE 2020 (Programa Operacional Região Norte) for his/her Post-Doc grant ref. SFRH/BPD/109153/2015). Juliana Guimarães was funded by FCT/MCTES (Foundation for Science and Technology and Ministry of Science, Technology and Higher Education) under CINTESIS by a PhD scholarship (reference UI/BD/152087/2021).info:eu-repo/semantics/publishedVersio

A percepção de voluntários e participantes sobre a X Semana de Extensão da Faculdade UnB Planaltina- FUP

As ações de extensão universitária viabilizam o processo de formação humana, cidadã e profissional, a partir de intervenções que unem o saber acadêmico ao fazer contextualizado e compartilhado com a comunidade que também compõe a universidade. Tais ações permitem, ainda, a investigação e a produção de novos conhecimentos e o desenvolvimento coletivo da sociedade. Neste trabalho, realizamos uma pesquisa com os voluntários e participantes das ações da X Semana de Extensão da Faculdade UnB Planaltina para identificar o impacto da ação para eles mesmos e para suas organizações de trabalho ou comunidade. Ao todo foram entrevistados, na modalidade presencial ou a distância, 20 pessoas entre voluntários e participantes das ações. Os resultados evidenciaram que para todos os participantes da pesquisa a semana de extensão permitiu a integração da universidade com as escolas, comunidade e organizações parceiras, porque abriu caminhos de diálogos e ações que não são tradicionais do espaço acadêmico, mas que deveriam ser, já que a universidade é para todos e deve ser feita com, para e por todos

Técnica de restauração atraumática: revisão da literatura

O tratamento restaurador atraumático envolve restaurações atraumáticas e procedimentos educativos-preventivos. Trata-se de uma forma simplificada de atendimento, que consiste na remoção do tecido cariado, com instrumentação manual. Este estudo tem como objetivo realizar uma revisão de literatura sobre as principais evidencias da técnica de restauração atraumática em lesões cariosas na odontopediatria. Foi realizada uma revisão bibliográfica nas bases de dados, PubMed, SciELO e Periódicos CAPES. A maioria dos estudos sobre a eficácia do ART demonstraram um bom resultado, isso é explicado pela praticidade da técnica e baixo custo, sendo apropriada a todo e qualquer segmento sócioeconômico, e não apenas a populações de baixa renda. A técnica é baseada em mínima intervenção, assim, a ART tem um enfoque preventivo-terapêutico e não somente restaurador, sendo uma opção na odontopediatria para contribuir para a redução da necessidade de tratamentos invasivos. Estudos usando o ART em crianças tem mostrando resultados promissores

TECNOLOGIAS DIGITAIS NA EDUCAÇÃO

The present study is aimed at discussing the emergence and incorporation of Digital Technologies in Education, nevertheless, aims to report on its propagation and its support during the pandemic context, relevance in the construction of meanings for the teaching-learning process and the role of the teacher. The research allows the deepening and amplification in the theme, thus, we used scientific articles arranged in the electronic bases Scielo, Google Scholar and Journals that contemplated the current theme for bibliographic survey. Additionally, we preferably sought productions developed in the period from 2018 to 2022. Thus, the research aims to propagate and amplify the knowledge about digital technologies in the area of education, as a facilitating and innovative resource for the occurrence of the teaching-learning process, bringing reflections on how individuals establish their relationships with these tools.  El presente estudio tiene como objetivo discutir el surgimiento e incorporación de las Tecnologías Digitales en la Educación, sin embargo, tiene como objetivo informar sobre su propagación y su apoyo durante el contexto de pandemia, la relevancia en la construcción de significados para el proceso de enseñanza-aprendizaje y el papel del docente. La investigación permite la profundización y amplificación en el tema, por lo tanto, se utilizaron artículos científicos dispuestos en las bases electrónicas Scielo, Google Scholar y Revistas que contemplaban el tema actual para la encuesta bibliográfica. Adicionalmente, buscamos preferentemente producciones desarrolladas en el periodo de 2018 a 2022. Por lo tanto, la investigación tiene como objetivo propagar y amplificar el conocimiento sobre las tecnologías digitales en el área de la educación, como un recurso facilitador e innovador para la ocurrencia del proceso de enseñanza-aprendizaje, trayendo reflexiones sobre cómo los individuos establecen sus relaciones con estas herramientas.O presente estudo ocupa-se em discorrer sobre o surgimento e incorporação das Tecnologias Digitais na Educação, não obstante, tem como objetivo relatar acerca da sua propagação e adesão durante o contexto pandêmico, relevância na construção de significados para o processo ensino-aprendizagem e o papel do professor. A pesquisa permite o aprofundamento e amplificação na temática, assim,  utilizou-se de artigos científicos dispostos nas bases eletrônicas Scielo, Google Acadêmico e Revistas que contemplassem a temática vigente para levantamento bibliográfico. Adicionalmente, buscou-se, preferencialmente, produções desenvolvidas no período de 2018 a 2022. Dessa forma, a pesquisa tem por escopo propagar e amplificar o saber acerca das tecnologias digitais na área da educação, como um recurso facilitador e inovador para a ocorrência do processo ensino-aprendizagem, trazendo reflexões sobre a forma como os indivíduos estabelecem suas relações com estas ferramentas.  O presente estudo ocupa-se em discorrer sobre o surgimento e incorporação das Tecnologias Digitais na Educação, não obstante, tem como objetivo relatar acerca da sua propagação e adesão durante o contexto pandêmico, relevância na construção de significados para o processo ensino-aprendizagem e o papel do professor. A pesquisa permite o aprofundamento e amplificação na temática, assim,  utilizou-se de artigos científicos dispostos nas bases eletrônicas Scielo, Google Acadêmico e Revistas que contemplassem a temática vigente para levantamento bibliográfico. Adicionalmente, buscou-se, preferencialmente, produções desenvolvidas no período de 2018 a 2022. Dessa forma, a pesquisa tem por escopo propagar e amplificar o saber acerca das tecnologias digitais na área da educação, como um recurso facilitador e inovador para a ocorrência do processo ensino-aprendizagem, trazendo reflexões sobre a forma como os indivíduos estabelecem suas relações com estas ferramentas.

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Práticas Educomunicativas

Esta publicação pretende divulgar as práticas educomunicativas realizadas em diferentes regiões do país e que estão sendo implantadas por nossos associados. O e-book Práticas Educomunicativas, que visa oferecer um material de uso prático que possa servir de apoio pedagógico em diferentes contextos, escolar ou de ações junto a instituições, apresenta 20 artigos de profissionais e pesquisadores que implementam ações que inter-relacionam comunicação e educação no contexto da educação apontando as experiências e processos de educomunicação e valorizando desta forma, o trabalho realizado por cada educomunicador oferecendo, ao leitor, um material de uso prático que possa servir de apoio pedagógico em diferentes contextos

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030