Star Formation in Nearby Early-Type Galaxies: The Radio Continuum Perspective

We present a 1.4 GHz Karl G. Jansky Very Large Array (VLA) study of a sample of early-type galaxies (ETGs) from the volume- and magnitude-limited ATLAS-3D survey. The radio morphologies of these ETGs at a resolution of 5" are diverse and include sources that are compact on sub-kpc scales, resolved structures similar to those seen in star-forming spiral galaxies, and kpc-scale radio jets/lobes associated with active nuclei. We compare the 1.4 GHz, molecular gas, and infrared (IR) properties of these ETGs. The most CO-rich ATLAS-3D ETGs have radio luminosities consistent with extrapolations from H_2-mass-derived star formation rates from studies of late-type galaxies. These ETGs also follow the radio-IR correlation. However, ETGs with lower molecular gas masses tend to have less radio emission relative to their CO and IR emission compared to spirals. The fraction of galaxies in our sample with high IR-radio ratios is much higher than in previous studies, and cannot be explained by a systematic underestimation of the radio luminosity due to the presence extended, low-surface-brightness emission that was resolved-out in our VLA observations. In addition, we find that the high IR-radio ratios tend to occur at low IR luminosities, but are not associated with low dynamical mass or metallicity. Thus, we have identified a population of ETGs that have a genuine shortfall of radio emission relative to both their IR and molecular gas emission. A number of mechanisms may conspire to cause this radio deficiency, including a bottom-heavy stellar initial mass function, weak magnetic fields, a higher prevalence of environmental effects compared to spirals and enhanced cosmic ray losses.Comment: accepted for publication in MNRA

Palaeogeographic controls on climate and proxy interpretation

During the period from approximately 150 to 35?million years ago, the Cretaceous–Paleocene–Eocene (CPE), the Earth was in a “greenhouse” state with little or no ice at either pole. It was also a period of considerable global change, from the warmest periods of the mid-Cretaceous, to the threshold of icehouse conditions at the end of the Eocene. However, the relative contribution of palaeogeographic change, solar change, and carbon cycle change to these climatic variations is unknown. Here, making use of recent advances in computing power, and a set of unique palaeogeographic maps, we carry out an ensemble of 19 General Circulation Model simulations covering this period, one simulation per stratigraphic stage. By maintaining atmospheric CO2 concentration constant across the simulations, we are able to identify the contribution from palaeogeographic and solar forcing to global change across the CPE, and explore the underlying mechanisms. We find that global mean surface temperature is remarkably constant across the simulations, resulting from a cancellation of opposing trends from solar and palaeogeographic change. However, there are significant modelled variations on a regional scale. The stratigraphic stage–stage transitions which exhibit greatest climatic change are associated with transitions in the mode of ocean circulation, themselves often associated with changes in ocean gateways, and amplified by feedbacks related to emissivity and planetary albedo. We also find some control on global mean temperature from continental area and global mean orography. Our results have important implications for the interpretation of single-site palaeo proxy records. In particular, our results allow the non-CO2 (i.e. palaeogeographic and solar constant) components of proxy records to be removed, leaving a more global component associated with carbon cycle change. This “adjustment factor” is used to adjust sea surface temperatures, as the deep ocean is not fully equilibrated in the model. The adjustment factor is illustrated for seven key sites in the CPE, and applied to proxy data from Falkland Plateau, and we provide data so that similar adjustments can be made to any site and for any time period within the CPE. Ultimately, this will enable isolation of the CO2-forced climate signal to be extracted from multiple proxy records from around the globe, allowing an evaluation of the regional signals and extent of polar amplification in response to CO2 changes during the CPE. Finally, regions where the adjustment factor is constant throughout the CPE could indicate places where future proxies could be targeted in order to reconstruct the purest CO2-induced temperature change, where the complicating contributions of other processes are minimised. Therefore, combined with other considerations, this work could provide useful information for supporting targets for drilling localities and outcrop studies

Past East Asian monsoon evolution controlled by paleogeography, not CO2

The East Asian monsoon plays an integral role in human society, yet its geological history and controlling processes are poorly understood. Using a general circulation model and geological data, we explore the drivers controlling the evolution of the monsoon system over the past 150 million years. In contrast to previous work, we find that the monsoon is controlled primarily by changes in paleogeography, with little influence from atmospheric CO2. We associate increased precipitation since the Late Cretaceous with the gradual uplift of the Himalayan-Tibetan region, transitioning from an ITCZ-dominated monsoon to a sea breeze–dominated monsoon. The rising region acted as a mechanical barrier to cold and dry continental air advecting into the region, leading to increasing influence of moist air from the Indian Ocean/South China Sea. We show that, apart from a dry period in the middle Cretaceous, a monsoon system has existed in East Asia since at least the Early Cretaceous

The Precision Array for Probing the Epoch of Reionization: 8 Station Results

We are developing the Precision Array for Probing the Epoch of Reionization (PAPER) to detect 21cm emission from the early Universe, when the first stars and galaxies were forming. We describe the overall experiment strategy and architecture and summarize two PAPER deployments: a 4-antenna array in the low-RFI environment of Western Australia and an 8-antenna array at our prototyping site in Green Bank, WV. From these activities we report on system performance, including primary beam model verification, dependence of system gain on ambient temperature, measurements of receiver and overall system temperatures, and characterization of the RFI environment at each deployment site. We present an all-sky map synthesized between 139 MHz and 174 MHz using data from both arrays that reaches down to 80 mJy (4.9 K, for a beam size of 2.15e-5 steradians at 154 MHz), with a 10 mJy (620 mK) thermal noise level that indicates what would be achievable with better foreground subtraction. We calculate angular power spectra ($C_\ell$) in a cold patch and determine them to be dominated by point sources, but with contributions from galactic synchrotron emission at lower radio frequencies and angular wavemodes. Although the cosmic variance of foregrounds dominates errors in these power spectra, we measure a thermal noise level of 310 mK at $\ell=100$ for a 1.46-MHz band centered at 164.5 MHz. This sensitivity level is approximately three orders of magnitude in temperature above the level of the fluctuations in 21cm emission associated with reionization.Comment: 13 pages, 14 figures, submitted to AJ. Revision 2 corrects a scaling error in the x axis of Fig. 12 that lowers the calculated power spectrum temperatur

Measuring the mass of the central black hole in the bulgeless galaxy ngc 4395 from gas dynamical modeling

NGC 4395 is a bulgeless spiral galaxy, harboring one of the nearest known type 1 Seyfert nuclei. Although there is no consensus on the mass of its central engine, several estimates suggest it is one of the lightest massive black holes (MBHs) known. We present the first direct dynamical measurement of the mass of this MBH from a combination of two-dimensional gas kinematic data, obtained with the adaptive optics assisted near-infrared integral field spectrograph Gemini/NIFS and high-resolution multiband photometric data from Hubble Space Telescope's Wide Field Camera 3. We use the photometric data to model the shape and stellar mass-to-light ratio of the nuclear star cluster (NSC). From the Gemini/NIFS observations, we derive the kinematics of warm molecular hydrogen gas as traced by emission through the H2 1–0 S(1) transition. These kinematics show a clear rotational signal, with a position angle orthogonal to NGC 4395's radio jet. Our best-fitting tilted ring models of the kinematics of the molecular hydrogen gas contain a black hole with mass M={4}-3+8× {10}5 M⊙ (3σ uncertainties) embedded in an NSC of mass M=2× {10}6 M⊙. Our black hole mass measurement is in excellent agreement with the reverberation mapping mass estimate of Peterson et al. but shows some tension with other mass measurement methods based on accretion signals

Disease risk analysis in sea turtles: a baseline study to inform conservation efforts

The impact of a range of different threats has resulted in the listing of six out of seven sea turtle species on the IUCN Red List of endangered species. Disease risk analysis (DRA) tools are designed to provide objective, repeatable and documented assessment of the disease risks for a population and measures to reduce these risks through management options. To the best of our knowledge, DRAs have not previously been published for sea turtles, although disease is reported to contribute to sea turtle population decline. Here, a comprehensive list of health hazards is provided for all seven species of sea turtles. The possible risk these hazards pose to the health of sea turtles were assessed and “One Health” aspects of interacting with sea turtles were also investigated. The risk assessment was undertaken in collaboration with more than 30 experts in the field including veterinarians, microbiologists, social scientists, epidemiologists and stakeholders, in the form of two international workshops and one local workshop. The general finding of the DRA was the distinct lack of knowledge regarding a link between the presence of pathogens and diseases manifestation in sea turtles. A higher rate of disease in immunocompromised individuals was repeatedly reported and a possible link between immunosuppression and environmental contaminants as a result of anthropogenic influences was suggested. Society based conservation initiatives and as a result the cultural and social aspect of interacting with sea turtles appeared to need more attention and research. A risk management workshop was carried out to acquire the insights of local policy makers about management options for the risks relevant to Queensland and the options were evaluated considering their feasibility and effectiveness. The sea turtle DRA presented here, is a structured guide for future risk assessments to be used in specific scenarios such as translocation and head-starting programs

Disease risk analysis in sea turtles: a baseline study to inform conservation efforts

The impact of a range of different threats has resulted in the listing of six out of seven sea turtle species on the IUCN Red List of endangered species. Disease risk analysis (DRA) tools are designed to provide objective, repeatable and documented assessment of the disease risks for a population and measures to reduce these risks through management options. To the best of our knowledge, DRAs have not previously been published for sea turtles, although disease is reported to contribute to sea turtle population decline. Here, a comprehensive list of health hazards is provided for all seven species of sea turtles. The possible risk these hazards pose to the health of sea turtles were assessed and “One Health” aspects of interacting with sea turtles were also investigated. The risk assessment was undertaken in collaboration with more than 30 experts in the field including veterinarians, microbiologists, social scientists, epidemiologists and stakeholders, in the form of two international workshops and one local workshop. The general finding of the DRA was the distinct lack of knowledge regarding a link between the presence of pathogens and diseases manifestation in sea turtles. A higher rate of disease in immunocompromised individuals was repeatedly reported and a possible link between immunosuppression and environmental contaminants as a result of anthropogenic influences was suggested. Society based conservation initiatives and as a result the cultural and social aspect of interacting with sea turtles appeared to need more attention and research. A risk management workshop was carried out to acquire the insights of local policy makers about management options for the risks relevant to Queensland and the options were evaluated considering their feasibility and effectiveness. The sea turtle DRA presented here, is a structured guide for future risk assessments to be used in specific scenarios such as translocation and head-starting programs

The EYA Tyrosine Phosphatase Activity Is Pro-Angiogenic and Is Inhibited by Benzbromarone

Eyes Absents (EYA) are multifunctional proteins best known for their role in organogenesis. There is accumulating evidence that overexpression of EYAs in breast and ovarian cancers, and in malignant peripheral nerve sheath tumors, correlates with tumor growth and increased metastasis. The EYA protein is both a transcriptional activator and a tyrosine phosphatase, and the tyrosine phosphatase activity promotes single cell motility of mammary epithelial cells. Since EYAs are expressed in vascular endothelial cells and cell motility is a critical feature of angiogenesis we investigated the role of EYAs in this process. Using RNA interference techniques we show that EYA3 depletion in human umbilical vein endothelial cells inhibits transwell migration as well as Matrigel-induced tube formation. To specifically query the role of the EYA tyrosine phosphatase activity we employed a chemical biology approach. Through an experimental screen the uricosuric agents Benzbromarone and Benzarone were found to be potent EYA inhibitors, and Benzarone in particular exhibited selectivity towards EYA versus a representative classical protein tyrosine phosphatase, PTP1B. These compounds inhibit the motility of mammary epithelial cells over-expressing EYA2 as well as the motility of endothelial cells. Furthermore, they attenuate tubulogenesis in matrigel and sprouting angiogenesis in the ex vivo aortic ring assay in a dose-dependent fashion. The anti-angiogenic effect of the inhibitors was also demonstrated in vivo, as treatment of zebrafish embryos led to significant and dose-dependent defects in the developing vasculature. Taken together our results demonstrate that the EYA tyrosine phosphatase activity is pro-angiogenic and that Benzbromarone and Benzarone are attractive candidates for repurposing as drugs for the treatment of cancer metastasis, tumor angiogenesis, and vasculopathies