Mass extinctions past and present: a unifying hypothesis

International audienceEnzymes are often referred to as the "agents of life" ? a very apt term, since essentially all life processes are controlled by them. Typically, these enzymes only function across a narrow band of environmental conditions, particularly temperature and pH. Ambient conditions that challenge these operating conspecifics trigger enzyme dysfunction. Here, it is proposed that the pH-dependent inactivation of a single enzyme, urease, provides a unifying kill-mechanism for at least four of the "big five" mass extinctions of the past 560 million years. The triggering of this kill-mechanism is suggested to be sensitive to both gradualistic and catastrophic environmental disturbances that cause the operating pH of urease-dependent organisms to cross enzymatic "dead zones", one of which is suggested to exist at ~pH 7.9. For a wide range of oceanic and terrestrial ecosystems, this pH threshold coincides with an atmospheric CO2 partial pressure (pCO2) of ~560 ppmv ? a level that at current CO2 emission trajectories may be exceeded as early as 2050. The urease hypothesis thus predicts an impending Anthropocene extinction event of equivalence to the "big five" unless future atmospheric pCO2 levels can be stabilised well below 560 ppmv. Immediate scientific discussion and testing is required to confirm the validity of the urease hypothesis

Regional-scale hydrological modelling using multiple-parameter landscape zones and a quasi-distributed water balance model

Regional-scale catchments are characterised typically by natural variability in climatic and land-surface features. This paper addresses the important question regarding the appropriate level of spatial disaggregation necessary to guarantee a hydrologically sound consideration of this variability. Using a simple hydrologic model along with physical catchment data, the problem is reconsidered as a model parameter identification problem. With this manner of thinking the subjective nature as to what to include in the disaggregation scheme is removed and the problem reconsidered in terms of what can be supported by the available data. With such an approach the relative merit of different catchment disaggregation schemes is viewed in terms of their ability to provide constrained parameterisations that can be explained in terms of the physical processes deemed active within a catchment. The outlined methodology was tested for a regional-scale catchment, located in eastern Australia, and involved using the quasi-distributed VIC catchment model to recover the characteristic responses resulting from the disaggregation of the catchment into combinations of climate, soil and vegetation characteristics. A land-surface classification based on a combination of soil depth and land cover type was found to provide the most accurate streamflow predictions during a 10-year validation period. Investigation of the uncertainty associated with the predictions due to weakly identified parameters however, revealed that a simpler classification based solely on land cover actually provided a more robust parameterisation of streamflow response. The result alludes to the hydrological importance of distinguishing between forested and non-forested land cover types at the regional-scale, and suggests that given additional information soil-depth / storage considerations may also have proved significant. Improvements to the outlined method are discussed in terms of increasing the informative content available to differentiate between competing catchment responses.</p> <p style='line-height: 20px;'><b>Keywords:</b> regional-scale, spatial variability, disaggregation, hydrotype, quasi-distributed, parameterisation, uncertaint

Regional-scale hydrological modelling using multiple-parameter landscape zones and a quasi-distributed water balance model

International audienceRegional-scale catchments are characterised typically by natural variability in climatic and land-surface features. This paper addresses the important question regarding the appropriate level of spatial disaggregation necessary to guarantee a hydrologically sound consideration of this variability. Using a simple hydrologic model along with physical catchment data, the problem is reconsidered as a model parameter identification problem. With this manner of thinking the subjective nature as to what to include in the disaggregation scheme is removed and the problem reconsidered in terms of what can be supported by the available data. With such an approach the relative merit of different catchment disaggregation schemes is viewed in terms of their ability to provide constrained parameterisations that can be explained in terms of the physical processes deemed active within a catchment. The outlined methodology was tested for a regional-scale catchment, located in eastern Australia, and involved using the quasi-distributed VIC catchment model to recover the characteristic responses resulting from the disaggregation of the catchment into combinations of climate, soil and vegetation characteristics. A land-surface classification based on a combination of soil depth and land cover type was found to provide the most accurate streamflow predictions during a 10-year validation period. Investigation of the uncertainty associated with the predictions due to weakly identified parameters however, revealed that a simpler classification based solely on land cover actually provided a more robust parameterisation of streamflow response. The result alludes to the hydrological importance of distinguishing between forested and non-forested land cover types at the regional-scale, and suggests that given additional information soil-depth / storage considerations may also have proved significant. Improvements to the outlined method are discussed in terms of increasing the informative content available to differentiate between competing catchment responses. Keywords: regional-scale, spatial variability, disaggregation, hydrotype, quasi-distributed, parameterisation, uncertaint

Internationalisation, cultural distance and country characteristics: a Bayesian analysis of SME's financial performance

Relying on the accounting data of a panel of 403 Italian manufacturing SMEs collected over a period of 5 years, we find results suggesting that multinationality per se does not impact on the economic performance of international small and medium sized firms. It is the characteristics of the country selected i.e. the political hazard, the financial stability and the economic performance that significantly influence SMEs financial performance. The management implication for small and medium sized firms selecting and entering new geographic markets is significant, since our results show that for SMEs it is the market selection process that really matters and not the degree of multinationality

The Use of Software Agents for Autonomous Control of a DC Space Power System

In order to enable manned deep-space missions, the spacecraft must be controlled autonomously using on-board algorithms. A control architecture is proposed to enable this autonomous operation for an spacecraft electric power system and then implemented using a highly distributed network of software agents. These agents collaborate and compete with each other in order to implement each of the control functions. A subset of this control architecture is tested against a steadystate power system simulation and found to be able to solve a constrained optimization problem with competing objectives using only local information

Simultaneous dynamic electrical and structural measurements of functional materials

A new materials characterization system developed at the XMaS beamline, located at the European Synchrotron Radiation Facility in France, is presented. We show that this new capability allows to measure the atomic structural evolution (crystallography) of piezoelectric materials whilst simultaneously measuring the overall strain characteristics and electrical response to dynamically (ac) applied external stimuli

Ethnic Differences in Perceptions of Alzheimer’s Disease: Implications for Seeking Assistance in Caring for an Ill Parent

Purpose: To examine ethnic differences in ratings of 1) condition severity, 2) need for medical assistance, and 3) likelihood of hiring a Healthcare Advocate (HCA) for an ill, elderly parent as a function of 1) parent’s cognitive state (Alzheimer’s disease [AD] or cognitively healthy), 2) parent’s physical malady (hip fracture or heart attack), and 3) distance (near or far from the parent), with an emphasis on the interaction between ethnicity and cognitive state. Method: Nine-hundred-seventy-four individuals who identified as White, Black, Hispanic, or Asian/Pacific Islander read a hypothetical vignette about an older man. The man’s physical malady (heart attack or hip fracture), cognitive state (AD or no AD), and physical distance from a close family member were manipulated in the vignette. Participants rated the severity of the medical condition and their likelihood of hiring an HCA. Results: Black and Asian/Pacific Islander participants did not differ from White participants on any outcomes. Unlike White participants, Hispanic participants did not rate the older man’s condition as more severe and were not more likely to seek assistance when he had AD than when he was cognitively healthy. Conclusion: Ethnic differences in perceptions of AD may be less extensive than previously thought. The medical severity of AD did not appear to be recognized among the Hispanic participants in our sample, suggesting that culturallysensitive AD education may be particularly important in this subgroup

Global and regional effects of the photochemistry of CH_3O_2NO_2: evidence from ARCTAS

Using measurements from the NASA Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS) experiment, we show that methyl peroxy nitrate (CH_3O_2NO_2) is present in concentrations of ~5–15 pptv in the springtime arctic upper troposphere. We investigate the regional and global effects of CH_3O_2NO_2 by including its chemistry in the GEOS-Chem 3-D global chemical transport model. We find that at temperatures below 240 K inclusion of CH_3O_2NO_2 chemistry results in decreases of up to ~20 % in NO_x, ~20 % in N_2O_5, ~5 % in HNO3, ~2 % in ozone, and increases in methyl hydrogen peroxide of up to ~14 %. Larger changes are observed in biomass burning plumes lofted to high altitude. Additionally, by sequestering NO_x at low temperatures, CH_3O_2NO_2 decreases the cycling of HO_2 to OH, resulting in a larger upper tropospheric HO_2 to OH ratio. These results may impact some estimates of lightning NO_x sources as well as help explain differences between models and measurements of upper tropospheric composition

A Semantic Grid Oriented to E-Tourism

With increasing complexity of tourism business models and tasks, there is a clear need of the next generation e-Tourism infrastructure to support flexible automation, integration, computation, storage, and collaboration. Currently several enabling technologies such as semantic Web, Web service, agent and grid computing have been applied in the different e-Tourism applications, however there is no a unified framework to be able to integrate all of them. So this paper presents a promising e-Tourism framework based on emerging semantic grid, in which a number of key design issues are discussed including architecture, ontologies structure, semantic reconciliation, service and resource discovery, role based authorization and intelligent agent. The paper finally provides the implementation of the framework.Comment: 12 PAGES, 7 Figure

The application of ultrasonic NDT techniques in tribology

The use of ultrasonic reflection is emerging as a technique for studying tribological contacts. Ultrasonic waves can be transmitted non-destructively through machine components and their behaviour at an interface describes the characteristics of that contact. This paper is a review of the current state of understanding of the mechanisms of ultrasonic reflection at interfaces, and how this has been used to investigate the processes of dry rough surface contact and lubricated contact. The review extends to cover how ultrasound has been used to study the tribological function of certain engineering machine elements