2,671 research outputs found

    Secondary Electron Yield Measurements of Carbon Nanotube Forests: Dependence on Morphology and Substrate

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    Total, secondary, and backscatter electron yield data were taken with beam energies between 15 eV and 30 keV, in conjunction with energy emission data, to determine the extent of suppression of yield caused by carbon nanotube (CNT) forest coatings on substrates. CNT forests can potentially lower substrate yield due to both its inherently low-yield, low-atomic number (Z) carbon composition, and its bundled, high-aspect ratio structure. Rough surfaces, and in particular, surfaces with deep high-aspect-ratio voids, can suppress yields, as the electrons emitted from lower lying surfaces are recaptured by surface protrusions rather than escaping the near-surface region. Yields of multilayered materials can be modeled essentially serially as a combination of the constituents. However, it is shown that suppression of yields due to CNT forest morphology is more significant than simple predicted contributions of homogeneous layered components. This effect is found to be most pronounced at low energies, where the incident electrons interact preferentially with the CNTs. CNT forests between 20 and 50 μm tall were grown on a thick silicon substrate capped with a 3-nm diffusion barrier of evaporated aluminum using a wet injection chemical vapor deposition (CVD) method. Yields of an annealed substrate and constituent bulk materials were also investigated. At incident electron energies above ~1200 eV, the substrate secondary yield dominated those of the CNT forests, as incident electrons penetrated through the low-density, low-Z CNT forests, and backscattered from the higher-Z substrate. At lower energies \u3c1200 \u3eeV, the CNT forests substantially reduced the overall yields of the substrate, and for \u3c500 eV CNT forest yields were \u3c1, well below the already low yields of bulk graphite. This suppressed yield at low energies is attributed to the porosity and preferred vertical alignment of the CNT forest. The yield’s dependence on the height and density of the CNT forest is also discussed

    Influence of Vibrationally-Induced Structural Changes on Carbon Nanotube Forests Suppression of Electron Yield

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    Carbon nanotube (CNT) forest coatings have been found to lower electron yield from material surfaces. The suppressed yields have been attributed to both the lower inherent yields of low-atomic number carbon and the enhanced electron recapture resulting from the morphology of the carbon layer. To explore the relative contributions of these two causes of yield suppression, tests have been made on CNT forest-coated conducting substrate samples subjected to vibrationally-induced changes of the coating structure. The extent of vibrationally-induced structural changes—due, for example, to shear-force conditions during space-vehicle transit—are of interest, as CNT have been a frequent topic of scientific curiosity and space applications due to their high tensile strength, high aspect ratio geometry, and unique electromagnetic characteristics. Their use has also been beneficial for sensor equipment, both terrestrial and space-faring, due to their extremely low photon and electron reflectivity

    Suppresion of Electron Yield With Carbon Nanotube Forests: A Case Study

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    Electron emission of carbon nanotube (CNT) forests grown on silicon substrates was measured to investigate possible electron yield suppression due to the composition and morphology of CNT forests. CNT forests are vertically-oriented tubular formations of graphitic carbon grown on a substrate; these have been widely investigated for their extreme properties in optical, electrical, and mechanical aspects of physics and material sciences. CNT coatings are good candidates for yield reduction, in analogy with the near-ideal blackbody optical properties of CNT forests. Carbon with its low atomic number has an inherent low yield due to its low density of bulk electrons. Furthermore, the large aspect ratio of this vertically-aligned CNT allows for easy penetration of the high energy incident electrons, but enhanced recapture of lower-energy secondary electrons due to their wider angular distribution of emission. Total (TEY), secondary (SEY) and backscattered (BSEY) yield curves using 15 eV to 30 keV electron beams, along with energy emission spectra, were acquired for three CNT forest samples to determine the extent of yield suppression of the substrate due to the CNT forests [Wood, 2018]

    A machine-learning derived model of seafloor sediment accumulation

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    Abstract Previous studies regarding the depositional pattern and quantity of accumulated seafloor sediment tend to be regional, limited in scope and involving costly and time-consuming geologic field campaigns and laboratory work. Presented herein is a global map of predicted modern (postindustrial, 20th and 21st century) oceanic mass accumulation rates of 5-arc-minute pitch and in log10-space, trained on observed marine mass accumulation rates from 43 peer reviewed sources (n = 1744) and predicted using a k-nearest neighbor geospatial algorithm. The resultant model predicts ~3.3 × 104 Mt. yr−1 of sediment accumulating onto the sea floor (R2 = 0.88). Most sediment accumulates proximal to major river outlets and deltas. Continental regions with the highest sediment accumulation are Asia and Oceania. This model is the first of its kind to predict the rate and quantity of sediment accumulating on to the ocean floor, globally, using decades of regional real-world observations. The generated global map of modern, benthic mass accumulation rates also serves to highlight areas of interest for future study in related fields, such as sediment dynamics and seafloor stability

    Movement Interventions for Children with Autism and Developmental Disabilities: An Evidence-Based Practice Project

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    This review explored the following question: Are the comprehensive treatment models Makoto Therapy, Brain Gym, and Interactive Metronome effective interventions for improving occupational performance including improving executive function, academic performance, and physical coordination in children and adolescents with Autism Spectrum Disorder (ASD)? Because current research on Interactive Metronome, Brain Gym®, and Makoto Therapy fails to address children and adolescents with autism spectrum disorder, presents multiple flaws in research design, and does not measure occupational outcomes such as occupational performance, we recommend that these interventions should not be used as comprehensive treatment models in occupational therapy. We recommend that more occupational-based, methodologically-sound research involving youth with ASD be conducted before implementing these interventions in occupational therapy practice

    Delivering transformative action in paediatric pain: a <i>Lancet Child &amp; Adolescent Health</i> Commission

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    Every infant, child, and adolescent will experience pain at times throughout their life. Childhood pain ranges from acute to chronic, and includes procedural, disease-related, breakthrough, and other types of pain. Despite its ubiquity, pain is a major challenge for individuals, families, health-care professionals, and societies. As a private mental experience, pain is often hidden and can go undiscussed or ignored. Undertreated, unrecognised, or poorly managed pain in childhood leads to important and long-lasting negative consequences that continue into adulthood, including continued chronic pain, disability, and distress. This undertreatment of pain should not continue, as there are available tools, expertise, and evidence to provide better treatment for childhood pain

    Establishing HZ43 A, Sirius B, and RX J185635-3754 as soft X-ray standards: a cross-calibration between the Chandra LETG+HRC-S, the EUVE spectrometer, and the ROSAT PSPC

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    The absolute calibration of space-borne instruments in the soft X-ray regime rests strongly on model spectra of hot white dwarfs. We analyze the Chandra LETG+HRC-S observations of the white dwarfs HZ43 A and Sirius B and of the neutron star RX J185635-3754 in order to resolve current uncertainties in the soft X-ray spectral fluxes and photospheric parameters of the three stars. We have obtained improved parameters for which fit the observations from the optical to the soft X-ray regime. Our approach allows us to quote their absolute spectral fluxes at selected wavelengths which may aid the calibration of other space-borne instruments.Comment: 15 pages, 9 figure

    Expression Levels of a Kinesin-13 Microtubule Depolymerase Modulates the Effectiveness of Anti-Microtubule Agents

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    Chemotherapeutic drugs often target the microtubule cytoskeleton as a means to disrupt cancer cell mitosis and proliferation. Anti-microtubule drugs inhibit microtubule dynamics, thereby triggering apoptosis when dividing cells activate the mitotic checkpoint. Microtubule dynamics are regulated by microtubule-associated proteins (MAPs); however, we lack a comprehensive understanding about how anti-microtubule agents functionally interact with MAPs. In this report, we test the hypothesis that the cellular levels of microtubule depolymerases, in this case kinesin-13 s, modulate the effectiveness of the microtubule disrupting drug colchicine.We used a combination of RNA interference (RNAi), high-throughput microscopy, and time-lapse video microscopy in Drosophila S2 cells to identify a specific MAP, kinesin-like protein 10A (KLP10A), that contributes to the efficacy of the anti-microtubule drug colchicine. KLP10A is an essential microtubule depolymerase throughout the cell cycle. We find that depletion of KLP10A in S2 cells confers resistance to colchicine-induced microtubule depolymerization to a much greater extent than depletion of several other destabilizing MAPs. Using image-based assays, we determined that control cells retained 58% (+/-2%SEM) of microtubule polymer when after treatment with 2 microM colchicine for 1 hour, while cells depleted of KLP10A by RNAi retained 74% (+/-1%SEM). Likewise, overexpression of KLP10A-GFP results in increased susceptibility to microtubule depolymerization by colchicine.Our results demonstrate that the efficacy of microtubule destabilization by a pharmacological agent is dependent upon the cellular expression of a microtubule depolymerase. These findings suggest that expression levels of Kif2A, the human kinesin-13 family member, may be an attractive biomarker to assess the effectiveness of anti-microtubule chemotherapies. Knowledge of how MAP expression levels affect the action of anti-microtubule drugs may prove useful for evaluating possible modes of cancer treatment

    Preliminary seismological and geological studies of the San Fernando, California, earthquake of February 9 1971

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    The San Fernando earthquake was the largest earthquake to occur in the metropolitan Los Angeles area in more than 50 years. It has tentatively been assigned a magnitude, M_L of 6.6, a focal depth of 13.0 km, and an epicentral location about 12 km east of Newhall, California, at 34°24.0'N, 118°23.7'W (Figure 1), but these figures undoubtedly will be modified as further data become available. Although the focal depth is not as well defined as the epicenter, it is consistent with other observations suggesting thrusting on a fault plane dipping north about 45 ° and breaking the surface in the Sylmar-San Fernando area (Figure 1). It should be emphasized that the hypocenter of the main shock represents only the point of initial rupture. Breaking, presumably, then propagated southward and upward from this point, so that the main geological and engineering effects were observed farther south where the fault was shallower and the displacement greater. The location of the main shock is based on readings from permanent stations of the Caltech network, as well as the U. S. Geological Survey station at Point Mugu (SBLG) and the California Department of Water Resources stations at Pyramid (PYR) and Cedar Springs (CSP). Portable Caltech seismographs were installed in the epicentral area as early as 3 hr following the main shock, and, within a few days, there were at least 30 portable units in the region operated by various groups and agencies

    Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions

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    During meiosis, Structural Maintenance of Chromosome (SMC) complexes underpin two fundamental features of meiosis: homologous recombination and chromosome segregation. While meiotic functions of the cohesin and condensin complexes have been delineated, the role of the third SMC complex, Smc5/6, remains enigmatic. Here we identify specific, essential meiotic functions for the Smc5/6 complex in homologous recombination and the regulation of cohesin. We show that Smc5/6 is enriched at centromeres and cohesin-association sites where it regulates sister-chromatid cohesion and the timely removal of cohesin from chromosomal arms, respectively. Smc5/6 also localizes to recombination hotspots, where it promotes normal formation and resolution of a subset of joint-molecule intermediates. In this regard, Smc5/6 functions independently of the major crossover pathway defined by the MutLγ complex. Furthermore, we show that Smc5/6 is required for stable chromosomal localization of the XPF-family endonuclease, Mus81-Mms4Eme1. Our data suggest that the Smc5/6 complex is required for specific recombination and chromosomal processes throughout meiosis and that in its absence, attempts at cell division with unresolved joint molecules and residual cohesin lead to severe recombination-induced meiotic catastroph
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