Gamma-ray bursts and X-ray melting of material as a potential source of chondrules and planets

The intense radiation from a gamma-ray burst (GRB) is shown to be capable of melting stony material at distances up to 300 light years which subsequently cool to form chondrules. These conditions were created in the laboratory for the first time when millimeter sized pellets were placed in a vacuum chamber in the white synchrotron beam at the European Synchrotron Radiation Facility (ESRF). The pellets were rapidly heated in the X-ray and gamma-ray furnace to above 1400 C melted and cooled. This process heats from the inside unlike normal furnaces. The melted spherical samples were examined with a range of techniques and found to have microstructural properties similar to the chondrules that come from meteorites. This experiment demonstrates that GRBs can melt precursor material to form chondrules that may subsequently influence the formation of planets. This work extends the field of laboratory astrophysics to include high power synchrotron sources.Comment: 8 pages, 10 figures. Proceedings of the 5th INTEGRAL Workshop, Munich 16-20 February 2004. High resolution figures available at http://bermuda.ucd.ie/%7Esmcbreen/papers/duggan_01.pd

Spitzer observations of Bow Shocks and Outflows in RCW 38

We report Spitzer observations of five newly identified bow shocks in the massive star-forming region RCW 38. Four are visible at IRAC wavelengths, the fifth is visible only at 24 microns. Chandra X-ray emission indicates that winds from the central O5.5 binary, IRS~2, have caused an outflow to the NE and SW of the central subcluster. The southern lobe of hot ionised gas is detected in X-rays; shocked gas and heated dust from the shock-front are detected with Spitzer at 4.5 and 24 microns. The northern outflow may have initiated the present generation of star formation, based on the filamentary distribution of the protostars in the central subcluster. Further, the bow-shock driving star, YSO 129, is photo-evaporating a pillar of gas and dust. No point sources are identified within this pillar at near- to mid-IR wavelengths. We also report on IRAC 3.6 & 5.8 micron observations of the cluster DBS2003-124, NE of RCW 38, where 33 candidate YSOs are identified. One star associated with the cluster drives a parsec-scale jet. Two candidate HH objects associated with the jet are visible at IRAC and MIPS wavelengths. The jet extends over a distance of ~3 pc. Assuming a velocity of 100 km/s for the jet material gives an age of about 30,000 years, indicating that the star (and cluster) are likely to be very young, with a similar or possibly younger age than RCW 38, and that star formation is ongoing in the extended RCW 38 region.Comment: 27 pages, 6 figures, accepted to Ap

Telangiectasia macularis eruptiva perstans: More Than Skin Deep

Systemic mastocytosis is a rare disease involving the infiltration and accumulation of active mast cells within any organ system. By far, the most common organ affected is the skin. Cutaneous manifestations of mastocytosis, including Urticaria Pigmentosa (UP), cutaneous mastocytoma or telangiectasia macularis eruptive perstans (TMEP), may indicate a more serious and potentially life-threatening underlying disease. The presence of either UP or TMEP in a patient with anaphylactic symptoms should suggest the likelihood of systemic mastocytosis, with the caveat that systemic complications are more likely to occur in patients with UP. TMEP can usually be identified by the typical morphology, but a skin biopsy is confirmative. In patients with elevated tryptase levels or those with frequent systemic manifestations, a bone marrow biopsy is essential in order to demonstrate mast cell infiltration. Further genetic testing for mutations of c-kit gene or the FIP1L1 gene may help with disease classification and/or therapeutic approaches. Rarely, TMEP has been described with malignancy, radiation therapy, and myeloproliferative disorders. A few familial cases have also been described. In this review, we discuss the clinical features, diagnosis and management of patients with TMEP. We also discuss the possible molecular pathogenesis and the role of genetics in disease classification and treatment

The Structure of the Star-forming Cluster RCW 38

We present a study of the structure of the high mass star-forming region RCW~38 and the spatial distribution of its young stellar population. Spitzer IRAC photometry 3-8um are combined with 2MASS near-IR data to identify young stellar objects by IR-excess emission from their circumstellar material. Chandra X-ray data are used to identify class III pre-main sequence stars lacking circumstellar material. We identify 624 YSOs: 23 class 0/I and 90 flat spectrum protostars, 437 Class II stars, and 74 Class III stars. We also identify 29 (27 new) O star candidates over the IRAC field. Seventy-two stars exhibit IR-variability, including seven class 0/I and 12 flat spectrum YSOs. A further 177 tentative candidates are identified by their location in the IRAC [3.6] vs. [3.6]-[5.8] cmd. We find strong evidence of subclustering in the region. Three subclusters were identified surrounding the central cluster, with massive and variable stars in each subcluster. The central region shows evidence of distinct spatial distributions of the protostars and pre-main sequence stars. A previously detected IR cluster, DB2001_Obj36, has been established as a subcluster of RCW 38. This suggests that star formation in RCW 38 occurs over a more extended area than previously thought. The gas to dust ratio is examined using the X-ray derived hydrogen column density, N_H and the K-band extinction, and found to be consistent with the diffuse ISM, in contrast with Serpens & NGC1333. We posit that the high photoionising flux of massive stars in RCW 38 affects the agglomeration of the dust grains.Comment: 98 pages, 15 figure

A Combined Spitzer and Chandra Survey of Young Stellar Objects in the Serpens Cloud Core

We present Spitzer and Chandra observations of the nearby (~260 pc) embedded stellar cluster in the Serpens Cloud Core. We observed, using Spitzer's IRAC and MIPS instruments, in six wavelength bands from 3 to 70 ${\mu}m$, to detect thermal emission from circumstellar disks and protostellar envelopes, and to classify stars using color-color diagrams and spectral energy distributions (SEDs). These data are combined with Chandra observations to examine the effects of circumstellar disks on stellar X-ray properties. Young diskless stars were also identified from their increased X-ray emission. We have identified 138 YSOs in Serpens: 22 class 0/I, 16 flat spectrum, 62 class II, 17 transition disk, and 21 class III stars; 60 of which exhibit X-ray emission. Our primary results are the following: 1.) ten protostars detected previously in the sub-millimeter are detected at lambda < 24 microns, seven at lambda < 8 microns, 2.) the protostars are more closely grouped than more evolved YSOs (median separation : ~0.024 pc, and 3.) the luminosity and temperature of the X-ray emitting plasma around these YSOs does not show any significant dependence on evolutionary class. We combine the infrared derived values of AK and X-ray values of NH for 8 class III objects and find that the column density of hydrogen gas per mag of extinctions is less than half the standard interstellar value, for AK > 1. This may be the result of grain growth through coagulation and/or the accretion of volatiles in the Serpens cloud core.Comment: 69 pages, 16 figures, accepted to ApJ. Higher Resolution Figures at: http://www.cfa.harvard.edu/~ewinston

Nkx2-5 and Sarcospan genetically interact in the development of the muscular ventricular septum of the heart

The muscular ventricular septum separates the flow of oxygenated and de-oxygenated blood in air-breathing vertebrates. Defects within it, termed muscular ventricular septal defects (VSDs), are common, yet less is known about how they arise than rarer heart defects. Mutations of the cardiac transcription factor NKX2-5 cause cardiac malformations, including muscular VSDs. We describe here a genetic interaction between Nkx2-5 and Sarcospan (Sspn) that affects the risk of muscular VSD in mice. Sspn encodes a protein in the dystrophin-glycoprotein complex. Sspn knockout (Sspn(KO)) mice do not have heart defects, but Nkx2-5(+/−)/Sspn(KO) mutants have a higher incidence of muscular VSD than Nkx2-5(+/−) mice. Myofibers in the ventricular septum follow a stereotypical pattern that is disrupted around a muscular VSD. Subendocardial myofibers normally run in parallel along the left ventricular outflow tract, but in the Nkx2-5(+/−)/Sspn(KO) mutant they commonly deviate into the septum even in the absence of a muscular VSD. Thus, Nkx2-5 and Sspn act in a pathway that affects the alignment of myofibers during the development of the ventricular septum. The malalignment may be a consequence of a defect in the coalescence of trabeculae into the developing ventricular septum, which has been hypothesized to be the mechanistic basis of muscular VSDs

Spitzer Observations of NGC 1333: A Study of Structure and Evolution in a Nearby Embedded Cluster

We present a comprehensive analysis of structure in the young, embedded cluster, NGC 1333 using members identified with Spitzer and 2MASS photometry based on their IR-excess emission. In total, 137 members are identified in this way, composed of 39 protostars and 98 more evolved pre-main sequence stars with disks. Of the latter class, four are transition/debris disk candidates. The fraction of exposed pre-main sequence stars with disks is 83% +/- 11%, showing that there is a measurable diskless pre-main sequence population. The sources in each of the Class I and Class II evolutionary states are shown to have very different spatial distributions relative to the distribution of the dense gas in their natal cloud. However, the distribution of nearest neighbor spacings among these two groups of sources are found to be quite similar, with a strong peak at spacings of 0.045 pc. Radial and azimuthal density profiles and surface density maps computed from the identified YSOs show that NGC 1333 is elongated and not strongly centrally concentrated, confirming previous claims in the literature. We interpret these new results as signs of a low velocity dispersion, extremely young cluster that is not in virial equilibrium.Comment: 59 pages, 20 figures, accepted to ApJ, verion with full resolution figures available at http://www.cfa.harvard.edu/~rgutermuth/preprints/gutermuth_ngc1333.pdf . Updated to fix astro-ph figure garblin

The Properties of X-ray Luminous Young Stellar Objects in the NGC 1333 and Serpens Embedded Clusters

We present Chandra X-ray data of the NGC 1333 embedded cluster, combining these data with existing Chandra data, Sptizer photometry and ground based spectroscopy of both the NGC 1333 & Serpens North clusters to perform a detailed study of the X-ray properties of two of the nearest embedded clusters to the Sun. In NGC 1333, a total of 95 cluster members are detected in X-rays, of which 54 were previously identified with Spitzer. Of the Spitzer sources, we detect 23% of the Class I protostars, 53% of the Flat Spectrum sources, 52% of the Class II, and 50% of the Transition Disk YSOs. Forty-one Class III members of the cluster are identified, bringing the total identified YSO population to 178. The X-ray Luminosity Functions (XLFs) of the NGC 1333 and Serpens clusters are compared to each other and the Orion Nebula Cluster. Based on this comparison, we obtain a new distance for the Serpens cluster of 360+22/-13 pc. The X-ray luminosity was found to depend on the bolometric luminosity as in previous studies of other clusters, and that Lx depends primarily on the stellar surface area. In the NGC 1333 cluster, the Class III sources have a somewhat higher X-ray luminosity for a given surface area. We also find evidence in NGC 1333 for a jump in the X-ray luminosity between spectral types of M0 and K7, we speculate that this may result from the presence of radiative zones in the K-stars. The gas column density vs. extinction in the NGC 1333 was found to be N_H = 0.89 +/- 0.13 x 10^22 A_K, this is lower than expected of the standard ISM but similar to that found previously in the Serpens Cloud Core.Comment: 58 pages, 14 figures, accepted by A