Teleconnection in the martian atmosphere during the 2001 planet-encircling dust storm

Introduction: In July 2001 (Martian year 25), Mars was enshrouded by a thick veil of dust which lasted for several months and obscured the observation of its surface to spacecraft cameras and ground-based telescopes. The emergence and rapid evolution (within a few days) of multiple, isolated, regional dust storms which eventually attained planetary scale extent were observed by NASA’s Mars Global Surveyor (MGS) spacecraft using high resolution camera images and the thermal profiles and dust opacity measurements pro-vided by the Thermal Emission Spectrometer (TES) [1, 2]. We have applied a technique used in Terrestrial meteorology (sequential data assimilation, [3]) to ob-tain a complete, four-dimensional evolution of all the atmospheric variables during the period of this planet-encircling dust storm, even those which were not di-rectly observed by the MGS satellite, such as surface pressure and winds. We assimilated TES nadir-pointing thermal profiles and total dust opacities in a global circulation model of the Martian atmosphere, developed jointly by the University of Oxford and the Open University in the United Kingdom, with the col-laboration of the Laboratoire de Météorologie Dyna-mique in Paris (UK-MGCM) [4, 5, 6]

Abundant and equipotent founder cells establish and maintain acute lymphoblastic leukaemia

High frequencies of blasts in primary acute lymphoblastic leukaemia (ALL) samples have the potential to induce leukaemia and to engraft mice. However, it is unclear how individual ALL cells each contribute to drive leukaemic development in a bulk transplant and the extent to which these blasts vary functionally. We used cellular barcoding as a fate mapping tool to track primograft ALL blasts in vivo. Our results show that high numbers of ALL founder cells contribute at similar frequencies to leukaemic propagation over serial transplants, without any clear evidence of clonal succession. These founder cells also exhibit equal capacity to home and engraft to different organs, although stochastic processes may alter the composition in restrictive niches. Our findings enhance the stochastic stem cell model of ALL by demonstrating equal functional abilities of singular ALL blasts and show that successful treatment strategies must eradicate the entire leukaemic cell population

Void elimination in screen printed thick film dielectric pastes

The problem is to understand the mechanisms for the formation and evolution of defects in wet screen printed layers. The primary objective is to know how best to alter the properties of the paste (rather than the geometry of the screen printing process itself) in order to eliminate the defects. With these goals in mind the work done during the Study Group reported here was as follows; to describe a simple model for the closure of craters, a model for the partial closure of vias, a possible mechanism for the formation of pinholes and finally a more detailed consideration of the screen printing process

The VAST Survey - III. The multiplicity of A-type stars within 75 pc

With a combination of adaptive optics imaging and a multi-epoch common proper motion search, we have conducted a large volume-limited (D $\le$ 75 pc) multiplicity survey of A-type stars, sensitive to companions beyond 30 au. The sample for the Volume-limited A-STar (VAST) survey consists of 435 A-type stars: 363 stars were observed with adaptive optics, 228 stars were searched for wide common proper motion companions and 156 stars were measured with both techniques. The projected separation coverage of the VAST survey extends from 30 to 45,000 au. A total of 137 stellar companions were resolved, including 64 new detections from the VAST survey, and the companion star fraction, projected separation distribution and mass ratio distribution were measured. The separation distribution forms a log-normal distribution similar to the solar-type binary distribution, but with a peak shifted to a significantly wider value of 387 (+132,-98) au. Integrating the fit to the distribution over the 30 to 10,000 au observed range, the companion star fraction for A-type stars is estimated as 33.8%+-2.6%. The mass ratio distribution of closer (<125 au) binaries is distinct from that of wider systems, with a flat distribution for close systems and a distribution that tends towards smaller mass ratios for wider binaries. Combining this result with previous spectroscopic surveys of A-type stars gives an estimate of the total companion star fraction of 68.9%+-7.0%. The most complete assessment of higher order multiples was estimated from the 156-star subset of the VAST sample with both adaptive optics and common proper motion measurements, combined with a literature search for companions, yielding a lower limit on the frequency of single, binary, triple, quadruple and quintuple A-type star systems of 56.4 (-4.0,+3.8), 32.1 (-3.5,+3.9), 9.0 (-1.8,+2.8), 1.9 (-0.6,+1.8) and 0.6 (-0.2,+1.4) per cent, respectively.Comment: 46 pages, 24 figures. Accepted for publication in the Monthly Notices of the Royal Astronomical Society, 7th October 201

Integration, productivity and technological spillovers: Evidence for eurozone banking industries

In the context of the current debate on increased integration of eurozone banking markets following the global financial and sovereign debt crises, this paper evaluates the impact of regulatory reform, starting from the inception of the Single Market in 1992, on bank productivity and assesses the cross-border benefits of integration in terms of technological spillovers. We utilise a parametric meta-frontier Divisia index to estimate productivity change and identify technological gaps. We then assess the extent to which productivity converges within and across banking industries as a result of technological spillovers. Our results suggest that productivity growth has occurred for eurozone countries, driven by technological progress, both at the country and the supra-country level, although the latter slows or in some cases reverses since the onset of the crisis. Technological spillovers do exist, and have led to progression toward the best technology. However, convergence is not complete and significant long run differences in productivity persist. Improvements in technology are increasingly concentrated in fewer banking industries

MURE : MCNP Utility for Reactor Evolution - Description of the methods, first applications and results

PACSInternational audienc

Leibniz, Acosmism, and Incompossibility

Leibniz claims that God acts in the best possible way, and that this includes creating exactly one world. But worlds are aggregates, and aggregates have a low degree of reality or metaphysical perfection, perhaps none at all. This is Leibniz’s tendency toward acosmism, or the view that there this no such thing as creation-as-a-whole. Many interpreters reconcile Leibniz’s acosmist tendency with the high value of worlds by proposing that God sums the value of each substance created, so that the best world is just the world with the most substances. I call this way of determining the value of a world the Additive Theory of Value (ATV), and argue that it leads to the current and insoluble form of the problem of incompossibility. To avoid the problem, I read “possible worlds” in “God chooses the best of all possible worlds” as referring to God’s ideas of worlds. These ideas, though built up from essences, are themselves unities and so well suited to be the value bearers that Leibniz’s theodicy requires. They have their own value, thanks to their unity, and that unity is not preserved when more essences are added

The aerosol-climate model ECHAM5-HAM

The aerosol-climate modelling system ECHAM5-HAM is introduced. It is based on a flexible microphysical approach and, as the number of externally imposed parameters is minimised, allows the application in a wide range of climate regimes. ECHAM5-HAM predicts the evolution of an ensemble of microphysically interacting internally- and externally-mixed aerosol populations as well as their size-distribution and composition. The size-distribution is represented by a superposition of log-normal modes. In the current setup, the major global aerosol compounds sulfate (SU), black carbon (BC), particulate organic matter (POM), sea salt (SS), and mineral dust (DU) are included. The simulated global annual mean aerosol burdens (lifetimes) for the year 2000 are for SU: 0.80 Tg(S) (3.9 days), for BC: 0.11 Tg (5.4 days), for POM: 0.99 Tg (5.4 days), for SS: 10.5 Tg (0.8 days), and for DU: 8.28 Tg (4.6 days). An extensive evaluation with in-situ and remote sensing measurements underscores that the model results are generally in good agreement with observations of the global aerosol system. The simulated global annual mean aerosol optical depth (AOD) is with 0.14 in excellent agreement with an estimate derived from AERONET measurements (0.14) and a composite derived from MODIS-MISR satellite retrievals (0.16). Regionally, the deviations are not negligible. However, the main patterns of AOD attributable to anthropogenic activity are reproduced