17,614 research outputs found

    Freezing of dynamical exponents in low dimensional random media

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    A particle in a random potential with logarithmic correlations in dimensions d=1,2d=1,2 is shown to undergo a dynamical transition at Tdyn>0T_{dyn}>0. In d=1d=1 exact results demonstrate that Tdyn=TcT_{dyn}=T_c, the static glass transition temperature, and that the dynamical exponent changes from z(T)=2+2(Tc/T)2z(T)=2 + 2 (T_c/T)^2 at high temperature to z(T)=4Tc/Tz(T)= 4 T_c/T in the glass phase. The same formulae are argued to hold in d=2d=2. Dynamical freezing is also predicted in the 2D random gauge XY model and related systems. In d=1d=1 a mapping between dynamics and statics is unveiled and freezing involves barriers as well as valleys. Anomalous scaling occurs in the creep dynamics.Comment: 5 pages, 2 figures, RevTe

    Temporal dynamics of aquatic communities and implications for pond conservation

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    Conservation through the protection of particular habitats is predicated on the assumption that the conservation value of those habitats is stable. We test this assumption for ponds by investigating temporal variation in macroinvertebrate and macrophyte communities over a 10-year period in northwest England. We surveyed 51 ponds in northern England in 1995/6 and again in 2006, identifying all macrophytes (167 species) and all macroinvertebrates (221 species, excluding Diptera) to species. The alpha-diversity, beta-diversity and conservation value of these ponds were compared between surveys. We find that invertebrate species richness increased from an average of 29. 5 species to 39. 8 species between surveys. Invertebrate gamma-diversity also increased between the two surveys from 181 species to 201 species. However, this increase in diversity was accompanied by a decrease in beta-diversity. Plant alpha-, beta and gamma-diversity remained approximately constant between the two periods. However, increased proportions of grass species and a complete loss of charophytes suggests that the communities are undergoing succession. Conservation value was not correlated between sampling periods in either plants or invertebrates. This was confirmed by comparing ponds that had been disturbed with those that had no history of disturbance to demonstrate that levels of correlation between surveys were approximately equal in each group of ponds. This study has three important conservation implications: (i) a pond with high diversity or high conservation value may not remain that way and so it is unwise to base pond conservation measures upon protecting currently-speciose habitats; (ii) maximising pond gamma-diversity requires a combination of late and early succession ponds, especially for invertebrates; and (iii) invertebrate and plant communities in ponds may require different management strategies if succession occurs at varying rates in the two groups

    Vector Meson Photoproduction with an Effective Lagrangian in the Quark Model

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    A quark model approach to the photoproduction of vector mesons off nucleons is proposed. Its starting point is an effective Lagrangian of the interaction between the vector meson and the quarks inside the baryon, which generates the non-diffractive s- and u- channel resonance contributions. Additional t-channel π0\pi^0 and σ\sigma exchanges are included for the ω\omega and ρ0\rho^0 production respectively to account for the large diffractive behavior in the small tt region as suggested by Friman and Soyeur. The numerical results are presented for the ω\omega and ρ\rho productions in four isospin channels with the same set of parameters, and they are in good agreement with the available data not only in ω\omega and ρ0\rho^0 productions but also in the charged ρ\rho productions where the additional t-channel σ\sigma exchange does not contribute so that it provides an important test to this approach. The investigation is also extended to the ϕ\phi photoproduction, and the initial results show that the non-diffractive behavior of the ϕ\phi productions in the large tt region can be described by the s- and u- channel contributions with significantly smaller coupling constants, which is consistent with the findings in the similar studies in the QHD framework. The numerical investigation has also shown that polarization observables are essential for identifying so-called "missing resonances".Comment: 36 pages, 10 PS figures, extended version of nucl-th/9711061 and nucl-th/9803021, submitted to PR

    The effects of applied water at various fractions of measured evapotranspiration on reproductive growth and water productivity of Thompson Seedless grapevines

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    The reproductive growth and water productivity (WPb) of Thompson Seedless grapevines were measured as a function of applied water amounts at various fractions of measured grapevine ETc for a total of eight irrigation treatments. Shoots were harvested numerous times during the growing season to calculate water productivity. Berry weight was maximized at the 0.6–0.8 applied water treatments across years. As applied water amounts increased soluble solids decreased. Berry weight measured at veraison and harvest was a linear function of the mean midday leaf water potential measured between anthesis and veraison and anthesis and harvest, respectively. As applied water amounts increased up to the 0.6–0.8 irrigation treatments there was a significant linear increase in yield. Yields at greater applied water amounts either leveled off or decreased. The reduction in yield on either side of the yearly maximum was due to fewer numbers of clusters per vine. Maximum yield occurred at an ETc ranging from 550 to 700 mm. Yield per unit applied water and WPb increased as applied water decreased. The results from this study demonstrated that Thompson Seedless grapevines can be deficit irrigated, increasing water use efficiency while maximizing yields

    Simulating JWST deep extragalactic imaging surveys and physical parameter recovery

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    International audienceWe present a new prospective analysis of deep multi-band imaging with the James Webb Space Telescope (JWST). In this work, we investigate the recovery of high-redshift 5  6 and redshifts of 0   5 galaxy samples can be reduced to < 0.01 arcmin−2 with a limited impact on galaxy completeness. We investigate multiple high-redshift galaxy selection techniques and find that the best compromise between completeness and purity at 5 <  z <  10 using the full redshift posterior probability distributions. In the EGS field, the galaxy completeness remains higher than 50% at magnitudes mUV <  27.5 and at all redshifts, and the purity is maintained above 80 and 60% at z ≤ 7 and 10, respectively. The faint-end slope of the galaxy UV luminosity function is recovered with a precision of 0.1–0.25, and the cosmic star formation rate density within 0.1 dex. We argue in favor of additional observing programs covering larger areas to better constrain the bright end

    Melting of two dimensional solids on disordered substrate

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    We study 2D solids with weak substrate disorder, using Coulomb gas renormalisation. The melting transition is found to be replaced by a sharp crossover between a high TT liquid with thermally induced dislocations, and a low TT glassy regime with disorder induced dislocations at scales larger than ξd\xi_{d} which we compute (ξdRcRa\xi_{d}\gg R_{c}\sim R_{a}, the Larkin and translational correlation lengths). We discuss experimental consequences, reminiscent of melting, such as size effects in vortex flow and AC response in superconducting films.Comment: 4 pages, uses RevTeX, Amssymb, multicol,eps

    Expertise differences in anticipatory judgements during a temporally and spatially occluded dynamic task

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    There is contradictory evidence surrounding the role of critical cues in the successful anticipation of penalty kick outcome. In the current study, skilled and less-skilled soccer goalkeepers were required to anticipate spatially (full body; hip region) and temporally (–160 ms, –80 ms before, foot–ball contact) occluded penalty kicks. The skilled group outperformed the less-skilled group in all conditions. Both groups performed better in the full body, compared to hip region condition. Later temporal occlusion conditions were associated with increased performance in the correct response and correct side analysis, but not for correct height. These data suggest that there is enough postural information from the hip region for skilled goalkeepers to make highly accurate predictions of penalty kick direction, however, other regions are needed in order to make predictions of height. These data demonstrate the evolution of cues over time and have implications for anticipation training

    Sigma-phase in Fe-Cr and Fe-V alloy systems and its physical properties

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    A review is presented on physical properties of the sigma-phase in Fe-Cr and Fe-V alloy systems as revealed both with experimental -- mostly with the Mossbauer spectroscopy -- and theoretical methods. In particular, the following questions relevant to the issue have been addressed: identification of sigma and determination of its structural properties, kinetics of alpha-to-sigma and sigma-to-alpha phase transformations, Debye temperature and Fe-partial phonon density of states, Curie temperature and magnetization, hyperfine fields, isomer shifts and electric field gradients.Comment: 26 pages, 23 figures and 83 reference

    Precision medicine for suicidality: from universality to subtypes and personalization

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    Suicide remains a clear, present and increasing public health problem, despite being a potentially preventable tragedy. Its incidence is particularly high in people with overt or un(der)diagnosed psychiatric disorders. Objective and precise identification of individuals at risk, ways of monitoring response to treatments and novel preventive therapeutics need to be discovered, employed and widely deployed. We sought to investigate whether blood gene expression biomarkers for suicide (that is, a ‘liquid biopsy’ approach) can be identified that are more universal in nature, working across psychiatric diagnoses and genders, using larger cohorts than in previous studies. Such markers may reflect and/or be a proxy for the core biology of suicide. We were successful in this endeavor, using a comprehensive stepwise approach, leading to a wealth of findings. Steps 1, 2 and 3 were discovery, prioritization and validation for tracking suicidality, resulting in a Top Dozen list of candidate biomarkers comprising the top biomarkers from each step, as well as a larger list of 148 candidate biomarkers that survived Bonferroni correction in the validation step. Step 4 was testing the Top Dozen list and Bonferroni biomarker list for predictive ability for suicidal ideation (SI) and for future hospitalizations for suicidality in independent cohorts, leading to the identification of completely novel predictive biomarkers (such as CLN5 and AK2), as well as reinforcement of ours and others previous findings in the field (such as SLC4A4 and SKA2). Additionally, we examined whether subtypes of suicidality can be identified based on mental state at the time of high SI and identified four potential subtypes: high anxiety, low mood, combined and non-affective (psychotic). Such subtypes may delineate groups of individuals that are more homogenous in terms of suicidality biology and behavior. We also studied a more personalized approach, by psychiatric diagnosis and gender, with a focus on bipolar males, the highest risk group. Such a personalized approach may be more sensitive to gender differences and to the impact of psychiatric co-morbidities and medications. We compared testing the universal biomarkers in everybody versus testing by subtypes versus personalized by gender and diagnosis, and show that the subtype and personalized approaches permit enhanced precision of predictions for different universal biomarkers. In particular, LHFP appears to be a strong predictor for suicidality in males with depression. We also directly examined whether biomarkers discovered using male bipolars only are better predictors in a male bipolar independent cohort than universal biomarkers and show evidence for a possible advantage of personalization. We identified completely novel biomarkers (such as SPTBN1 and C7orf73), and reinforced previously known biomarkers (such as PTEN and SAT1). For diagnostic ability testing purposes, we also examined as predictors phenotypic measures as apps (for suicide risk (CFI-S, Convergent Functional Information for Suicidality) and for anxiety and mood (SASS, Simplified Affective State Scale)) by themselves, as well as in combination with the top biomarkers (the combination being our a priori primary endpoint), to provide context and enhance precision of predictions. We obtained area under the curves of 90% for SI and 77% for future hospitalizations in independent cohorts. Step 5 was to look for mechanistic understanding, starting with examining evidence for the Top Dozen and Bonferroni biomarkers for involvement in other psychiatric and non-psychiatric disorders, as a mechanism for biological predisposition and vulnerability. The biomarkers we identified also provide a window towards understanding the biology of suicide, implicating biological pathways related to neurogenesis, programmed cell death and insulin signaling from the universal biomarkers, as well as mTOR signaling from the male bipolar biomarkers. In particular, HTR2A increase coupled with ARRB1 and GSK3B decreases in expression in suicidality may provide a synergistic mechanistical corrective target, as do SLC4A4 increase coupled with AHCYL1 and AHCYL2 decrease. Step 6 was to move beyond diagnostics and mechanistical risk assessment, towards providing a foundation for personalized therapeutics. Items scored positive in the CFI-S and subtypes identified by SASS in different individuals provide targets for personalized (psycho)therapy. Some individual biomarkers are targets of existing drugs used to treat mood disorders and suicidality (lithium, clozapine and omega-3 fatty acids), providing a means toward pharmacogenomics stratification of patients and monitoring of response to treatment. Such biomarkers merit evaluation in clinical trials. Bioinformatics drug repurposing analyses with the gene expression biosignatures of the Top Dozen and Bonferroni-validated universal biomarkers identified novel potential therapeutics for suicidality, such as ebselen (a lithium mimetic), piracetam (a nootropic), chlorogenic acid (a polyphenol) and metformin (an antidiabetic and possible longevity promoting drug). Finally, based on the totality of our data and of the evidence in the field to date, a convergent functional evidence score prioritizing biomarkers that have all around evidence (track suicidality, predict it, are reflective of biological predisposition and are potential drug targets) brought to the fore APOE and IL6 from among the universal biomarkers, suggesting an inflammatory/accelerated aging component that may be a targetable common denominator

    Quantum Gravity in Large Dimensions

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    Quantum gravity is investigated in the limit of a large number of space-time dimensions, using as an ultraviolet regularization the simplicial lattice path integral formulation. In the weak field limit the appropriate expansion parameter is determined to be 1/d1/d. For the case of a simplicial lattice dual to a hypercube, the critical point is found at kc/λ=1/dk_c/\lambda=1/d (with k=1/8πGk=1/8 \pi G) separating a weak coupling from a strong coupling phase, and with 2d22 d^2 degenerate zero modes at kck_c. The strong coupling, large GG, phase is then investigated by analyzing the general structure of the strong coupling expansion in the large dd limit. Dominant contributions to the curvature correlation functions are described by large closed random polygonal surfaces, for which excluded volume effects can be neglected at large dd, and whose geometry we argue can be approximated by unconstrained random surfaces in this limit. In large dimensions the gravitational correlation length is then found to behave as log(kck)1/2| \log (k_c - k) |^{1/2}, implying for the universal gravitational critical exponent the value ν=0\nu=0 at d=d=\infty.Comment: 47 pages, 2 figure
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