Klage gegen den Länderfinanzausgleich: Ein richtiger Schritt gegen unfaire Verteilung?

Hessen und Bayern, zwei der drei Geberländer, reichten ihre Klage gegen den Länderfinanzausgleich beim Bundesverfassungsgericht ein. Ist dies ein überfälliger Schritt gegen eine unfaire Verteilung? Aus Sicht von Volker Bouffier, Ministerpräsident des Landes Hessen, geht die Klage nicht gegen »den Länderfinanzausgleich«, und niemand ist unsolidarisch. Beklagt werden Fehlentwicklungen und Defizite des geltenden Ausgleichssystems, die dessen Mängel einseitig zu Lasten der Zahlerländer verteilen. Norbert Walter-Borjans, Finanzminister des Landes Nordrhein-Westfalen, bezeichnet dagegen das Verhalten der Kläger als unsolidarisch. Grundsätzlich habe sich das System des bundesstaatlichen Finanzausgleichs, selbst in außergewöhnlichen Situationen wie nach der Herstellung der deutschen Einheit, bewährt. Für Rolf Peffekoven, Universität Mainz, ist der Unmut der Länder Bayern und Hessen nachvollziehbar. Eine Reform müsse aber das gesamte Ausgleichssystem erfassen. Ob man mit einer Klage vor dem Bundesverfassungsgericht viel erreichen könne, sei zweifelhaft. Joachim Wieland, Deutsche Universität für Verwaltungswissenschaften Speyer, sieht nicht hohe Zahlungen bei hoher Leistungskraft als unfair an, sondern eine gesetzliche Regelung, die das verfassungsrechtlich vorgegebene Ziel eines angemessenen Ausgleichs verfehle. Die Probleme müssen allerdings politisch gelöst werden. Thomas Lenk, Universität Leipzig, betont, dass die Antwort nach der richtigen Verteilung immer Werturteile einschließt. Deshalb sei die Frage, welche Bedarfe in welchem Maße in einem Finanzausgleichsystem berücksichtigt werden sollten, nur politisch zu beantworten. Nach Meinung von Nathalie Behnke, Universität Konstanz, ist zwar eine starke einseitige Belastung weniger Länder kaum zu rechtfertigen. Dass die ungleich verteilte Finanz- und Wirtschaftskraft ebenso wie Soziallasten im Bundesgebiet solidarisch getragen werden müssen, stehe aber nicht grundlegend zur Diskussion. Der Gang nach Karlsruhe sei für eine g

Rhodiosin and herbacetin in Rhodiola rosea preparations: additional markers for quality control?

Context: Rhodiola rosea L. (Crassulaceae) is well-known to contain flavonoids such as the herbacetin derivative rhodiosin. However, flavonoids are not typically used in quality control. Objective: This study analyses two flavonoids of R. rosea rhizomes and roots for their potential as analytical markers. Materials and methods: Two constituents were isolated from ethanolic extracts via HPLC, identified via NMR and quantified via RP-HPLC. Presence and content variation was investigated according to extraction (solvent and repetitions), drying (temperature and duration) and sample origin (homogenously cultivated plants of different provenance, commercial samples). Results: Rhodiosin was identified as a main flavonoid, accompanied by 10-fold lower concentrated herbacetin. Both compounds were best extracted with 70–90% ethanol, but were also detectable in more aqueous extracts. Different drying conditions had no effect on the flavonoid content. These two flavonoids were consistently identified in rhizome and root extracts of over 100 R. rosea samples. Rhizomes tend to contain less flavonoids, with average ratios of rosavins to flavonoids of 1.4 (rhizomes) and 0.4 (roots). Provenance differences were detected in the range (rhodiosin plus herbacetin) of 760–6300 µg/mL extract corresponding to a maximum of approximately 0.5–4.2% (w/w) in the dry drug. Conclusions: For the first time, two main flavonoids present in R. rosea were quantified systematically. Rhodiosin and herbacetin can be detected simultaneously to phenylpropenoids or salidroside in authentic samples, influenced by the plant part examined and the plant origin. Rhodiosin and herbacetin may serve as additional marker to guarantee a consistent content of R. rosea products

Beaware!—situation awareness, the ontology-driven way.

Abstract Information overload is a severe problem for human operators of large-scale control systems as, for example, encountered in the domain of road traffic management. Operators of such systems are at risk to lack situation awareness, because existing systems focus on the mere presentation of the available information on graphical user interfaces-thus endangering the timely and correct identification, resolution, and prevention of critical situations. In recent years, ontologybased approaches to situation awareness featuring a semantically richer knowledge model have emerged. However, current approaches are either highly domain-specific or have, in case they are domain-independent, shortcomings regarding their reusability. In this paper, we present our experience gained from the development of BeAware!, a framework for ontology-driven information systems aiming at increasing an operator's situation awareness. In contrast to existing domain-independent approaches, BeAware!'s ontology introduces the concept of spatio-temporal primitive relations between observed real-world objects thereby improving the reusability of the framework. To show its applicability, a prototype of BeAware! has been implemented in the domain of road traffic management. An overview of this prototype and lessons learned for the development of ontology-driven information systems complete our contribution

Time of Lactation and Maternal Fucosyltransferase Genetic Polymorphisms Determine the Variability in Human Milk Oligosaccharides

Rationale: Human milk oligosaccharides (HMOs) vary among mothers and genetic factors contribute to this variability.We assessed changes in HMO concentrations during the first year of lactation and the relationship with FUT2 Secretor group and FUT3 Lewis group defining genetic polymorphisms. Methods: Milk samples were collected from lactating mothers participating in the LIFE Child cohort in Leipzig, Germany. The concentrations of 24 HMOs in milk samples collected at 3 months (N = 156), 6 months (N = 122), and 12 months (N = 28) were measured using liquid chromatography. Concentrations of HMOs were compared at all time-points and were tested for their associations with FUT2 and FUT3 genetic variations by sPLS regression. Results: FUT2 SNP rs601338 was found to predominantly define the Secretor status Se-: 11.8% and it was highly correlated with 2′-fucosyllactose (2′FL, p < 0.001) and lacto-N-fucosylpentaose-I (LNFP-I, p < 0.001). FUT3 SNPs rs28362459 and rs812936 were found to define Lewis status (Le-: 5.9%) and correlated with lacto-N-fucosylpentaose-II (LNFP-II, p < 0.001). A polygenic score predicted the abundance of 2′FL levels within Secretors’ milk (adj. R2 = 0.58, p < 0.001). Mean concentrations of most of the individual HMOs, as well as the sums of the measured HMOs, the fucosylated HMOs, and the neutral HMOs were lower at 6 and 12 months compared to 3 months (p < 0.001). Conclusions: Secretor and Lewis status defined by specific FUT2 and FUT3 SNPs are confirmed to be good proxies for specific individual HMOs and milk group variabilities. The polygenic score developed here is an opportunity for clinicians to predict 2′FL levels in milk of future mothers. These results show opportunities to strengthen our understanding of factors controlling FUT2 and FUT3 functionality, the temporal changes and variability of HMO composition during lactation and eventually their significance for infant development

Anthropogenic fire patterns affect niche breadth and niche overlap in sympatric songbird species

The severity of wildfires increases globally, and return intervals decrease. Fires can benefit biodiversity, as post-burn early successional stages provide diverse habitats and niches for many species. How fire disturbance affects niche use and niche overlap of species is poorly understood so far. We studied the effect of anthropogenic fire on breeding habitat use, niche breadth and niche overlap of five sympatric bunting species breeding in wetlands of the Amur River floodplain (Russian Far East). Fire frequency, measured as the time an area burnt in the period 2000 to 2017, was mapped from Landsat imagery and related to the presence or absence of the species. Niche breadth and niche overlap were calculated separately for occurrences in burned (within the study year) and unburned patches. Fire frequency characterized differences in niche use among the species, but the probability of presence was not affected by recent fire in four of five species. Niche breadth was significantly lower in recently burned patches, but we found no increase in niche overlap between species after fire. Instead, the studied species seemed to occupy similar patches before and after fire, possibly because of a high site fidelity. Our results clearly show that fire frequency is a major determinant for the niche separation in the five studied species, while recent fire does not affect niche overlap.</p

Identification of Ser-1275 and Ser-1309 as autophosphorylation sites of the insulin receptor 1This paper is dedicated to Prof. Günter Legler on the occasion of his 70th birthday.1

AbstractWe have identified Ser-1275 and Ser-1309 as novel serine autophosphorylation sites by direct sequencing of HPLC-purified tryptic phosphopeptides of the histidine-tagged insulin receptor kinase IRKD-HIS. The corresponding peptides (Ser-1275, amino acids 1272–1292; Ser-1309, amino acids 1305–1313) have been detected in the HPLC profiles of both the soluble kinase IRKD, which contains the entire cytoplasmic domain of the insulin receptor β-subunit, and the insulin receptor purified from human placenta. In contrast, a kinase negative mutant, IRKD-K1018A, did not undergo phosphorylation at either the tyrosine or serine residues, strongly suggesting that insulin receptor kinase has an intrinsic activity to autophosphorylate serine residues

Baltic cod recruitment – the impact of climate variability on key processes

Large-scale climatic conditions prevailing over the central Baltic Sea resulted in declining salinity and oxygen concentrations in spawning areas of the eastern Baltic cod stock. These changes in hydrography reduced the reproductive success and, combined with high fishing pressure, caused a decline of the stock to the lowest level on record in the early 1990s. The present study aims at disentangling the interactions between reproductive effort and hydrographic forcing leading to variable recruitment. Based on identified key processes, stock dynamics is explained using updated environmental and life stage-specific abundance and production time-series. Declining salinities and oxygen concentrations caused high egg mortalities and indirectly increased egg predation by clupeid fish. Low recruitment, despite enhanced hydrographic conditions for egg survival in the mid-1990s, was due to food limitation for larvae, caused by the decline in the abundance of the copepod Pseudocalanus sp. The case of the eastern Baltic cod stock exemplifies the multitude effects climatic variability may have on a fish stock and underscores the importance of knowledge of these processes for understanding stock dynamics

Using geolocator tracking data and ringing archives to validate citizen-science based seasonal predictions of bird distribution in a data-poor region

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Fire in lichen-rich subarctic tundra changes carbon and nitrogen cycling between ecosystem compartments but has minor effects on stocks

Fires are predicted to increase in Arctic regions due to ongoing climate change. Tundra fires can alter carbon and nutrient cycling and release a substantial quantity of greenhouse gases with global consequences. Yet, the long-term effects of tundra fires on carbon (C) and nitrogen (N) stocks and cycling are still unclear. Here we used a space-for-time approach to investigate the long-term fire effects on C and N stocks and cycling in soil and aboveground living biomass. We collected data from three large fire scars (>44, 28, and 12 years old) and corresponding control areas and used linear mixed-effect models in a Bayesian framework to analyse long-term development of C and N stocks and cycling after fire.We found that tundra fires had no long-term effect on total C and N stocks because a major part of the stocks was located belowground in soils which were largely unaltered by fire. However, fire had a strong long-term effect on stocks in the aboveground vegetation, mainly due to the reduction in the lichen layer. Fire reduced N concentrations in graminoids and herbs on the younger fire scars, which affected respective C/N ratios and may indicate an increased post-fire competition between vascular plants. Aboveground plant biomass was depleted in C-13 in all three fire scars. In soil, the relative abundance of C-13 changed with time after fire.Our results indicate that in lichen-rich subarctic tundra ecosystems, the contribution of fires to the release of additional carbon to the atmosphere might be relatively small as soil stocks appear to be resilient within the observed time frame