Notes from lockdown: A series of reflections on some of the political and cultural impacts of the pandemic

A series of reflections on Covid-19 that looks at: how the pandemic affects processes of bordering and increases the indeterminate grey zones within which so many people are forced to live; the way nurses are presented in the media and the hypocrisy of praising them in a moment of crisis while simultaneously devaluing their work and underpaying them; health inequalities in Newham; the inequalities in the craft sector spotlighted by the pandemic; the relationships between radical neighbourliness and local politics; how perceptions of time have been affected during lockdown - and how 24-7 capitalism may seek to take advantage of this radical reorganisation of time

Enhancing dental electives through participatory research

Completion of an elective project at the University of Glasgow Dental School is a progression requirement that entails a period of self-directed and enquiry-led learning. This study sought to uncover students’ expectations and perspectives of their elective experience as there is a scarcity of supporting literature to determine if this activity has significant educational value. This qualitative study utilised a participatory research methodology, ensuring that students were at the centre of the enquiry process. Three student co-researchers analysed data collected from their peers, using a questionnaire and a focus group meeting. The findings support maintaining autonomous, enquiry-led, independent learning-focused electives and also highlight aspects of the elective which students particularly valued. This has allowed a deeper understanding of students’ perceptions of, and motivations for, particular elective projects, enabling the elective programme to respond to changing environments in education and global health. The outcomes of this study have informed the redesign of the dental elective study programme and the associated quality assurance process

Just One? Solo Dining, Gender and Temporal Belonging in Public Spaces

In recent years, various lifestyle websites have offered tips on eating out alone as well as lists of the best restaurants for solo dining in major cities of the world. Utilising the theoretical concepts of participation units, territories of the self (Goffman 1972[1971]) and belonging (Author B2011, 2013), this paper explores the challenges that spatio-temporal conventions pose for women solo diners in particular. Through the lens of solo dining, we explore being alone and belonging in shared public spaces, and the gendered nature of aloneness and respectability. The papercontributes to existing theory by examining the influence that time has on a woman solo diner’s ‘single’ participation unit, her ability to lay claim to public space and her relationship with the surrounding social environment. The paper concludes by exploring what the new trend of solo dining can offer and the consequences this has for how sociologists conceptualise sociality inpublic spaces

Migration, Racism and the Hostile Environment: Making the Case for the Social Sciences

Cite as: Social Scientists Against the Hostile Environment (SSAHE)(2020). Migration, racism and the hostile environment : Making the case for the social sciences. London. https://acssmigration.wordpress.com/report/

Social innovation supports inclusive and accelerated energy transitions with appropriate governance

Accelerating energy transitions that are both sustainable and just remains an important challenge, and social innovation can have a key role in this transition. Here, we examine the diversity and potential of social innovation in energy systems transformation, synthesizing original mixed methods data from expert interviews, document analysis, social innovation experiments, a representative survey, and an expert survey. Based on a thematic analysis of these data, we advance four key findings: (1) the diversity of social innovation in energy is best understood when recognizing core social practices (thinking, doing, and organizing) and accounting for changes in social relations (cooperation, exchange, competition, and conflict); (2) governance, policy networks, and national context strongly shape social innovation dynamics; (3) processes of social innovation are implicated by multidimensional power relations that can result in transformative changes; and (4) social innovation in energy generally has strong social acceptance among citizens, benefits local communities and is legitimized in key community and city organizations. We discuss an agenda for 9 future research directions on social innovation in energy, and conclude with insights related to national context, governance, and acceleration

Direct detection and measurement of wall shear stress using a filamentous bio-nanoparticle

The wall shear stress (WSS) that a moving fluid exerts on a surface affects many processes including those relating to vascular function. WSS plays an important role in normal physiology (e.g. angiogenesis) and affects the microvasculature's primary function of molecular transport. Points of fluctuating WSS show abnormalities in a number of diseases; however, there is no established technique for measuring WSS directly in physiological systems. All current methods rely on estimates obtained from measured velocity gradients in bulk flow data. In this work, we report a nanosensor that can directly measure WSS in microfluidic chambers with sub-micron spatial resolution by using a specific type of virus, the bacteriophage M13, which has been fluorescently labeled and anchored to a surface. It is demonstrated that the nanosensor can be calibrated and adapted for biological tissue, revealing WSS in micro-domains of cells that cannot be calculated accurately from bulk flow measurements. This method lends itself to a platform applicable to many applications in biology and microfluidics

Clinical improvement and radiological progression in a girl with early onset scoliosis (EOS) treated conservatively – a case report

BACKGROUND: Chêneau-Brace treatment of a certain standard reduces the rate of surgery, prevents progression and in a certain patient population leads to marked improvement of Cobb angle and cosmetic appearance. During the last two years a patient refusing surgery with a double major curvature of initially 60° showed a clear cosmetic improvement and a clear radiological progression at the same time. The findings of this patient have been reviewed in order to find out how cosmetic appearance and Cobb angle can develop differently. METHODS: The patient entered conservative treatment at the age of 13 years, premenarchial with Tanner II and a Cobb angle of 60° thoracic and 59° lumbar. The angle of trunk rotation (ATR; Scoliometer) was 13° thoracic and 13° lumbar. We have documented the findings of this patient (Surface topography, ATR, Cobb angles and angles of vertebral rotation (according to Raimondi) during the treatment period (27 Month) until 2 years after the onset of menarche. RESULTS: After a treatment time of 27 Month the Cobb angle increased to 74° thoracic and 65° lumbar. The angles of vertebral rotation according to Raimondi increased slightly from 26° thoracic and 28° lumbar to 30° thoracic and 28° lumbar. The ATR improved to 12° thoracic and 5° lumbar while Lateral deviation improved from 22,4 mm to 4,6 mm and average surface rotation improved from 10,6° to 6°. In the X-rays a reduction of decompensation was visible. The patient felt comfortable with the cosmetic result. CONCLUSION: Conservative treatment may improve cosmetic appearance while the curve progresses radiologically. This could be explained by assuming that (1) the Rigo Chêneau brace is able to improve cosmetic appearance by changing the shape of the thorax when the curve itself is too stiff to be corrected by a brace, that (2) reduction of decompensation leads to significant cosmetical improvements or (3) that the patient gained weight and therefore the deformation is masked. However, the weight the patient gained cannot explain the cosmetical improvement in this case. Conservative treatment with a certain standard of quality seems a viable alternative for patients with Cobb angles of > 60° when surgical treatment is refused. Specialists in scoliosis management should be aware of the fact that curve progression can occur even if the clinical measurements show an improvement

Whiteness and diasporic Irishness: nation, gender and class

Whiteness is often detached from the notion of diaspora in the recent flurry of interest in the phenomenon, yet it is a key feature of some of the largest and oldest displacements. This paper explores the specific contexts of white racial belonging and status over two centuries in two main destinations of the Irish diaspora, the USA and Britain. Its major contribution is a tracing of the untold story of ‘How the Irish became white in Britain’ to parallel and contrast with the much more fully developed narrative in the USA. It argues that, contrary to popular belief, the racialisation of the Irish in England did not fade away at the end of the nineteenth century but became transmuted in new forms which have continued to place the ‘white’ Irish outside the boundaries of the English nation. These have been strangely ignored by social scientists, who conflate Irishness and working-class identities in England without acknowledging the distinctive contribution of Irish backgrounds to constructions of class difference. Gender locates Irish women and men differently in relation to these class positions, for example allowing mothers to be blamed for the perpetuation of the underclass. Class and gender are also largely unrecognised dimensions of Irish ethnicity in the USA, where the presence of ‘poor white’ neighbourhoods continues to challenge the iconic story of Irish upward mobility. Irishness thus remains central to the construction of mainstream ‘white’ identities in both the USA and Britain into the twenty-first century

Attaching and effacing (A/E) lesion formation by enteropathogenic E. coli on human intestinal mucosa is dependent on non-LEE effectors

Enteropathogenic E. coli (EPEC) is a human pathogen that causes acute and chronic pediatric diarrhea. The hallmark of EPEC infection is the formation of attaching and effacing (A/E) lesions in the intestinal epithelium. Formation of A/E lesions is mediated by genes located on the pathogenicity island locus of enterocyte effacement (LEE), which encode the adhesin intimin, a type III secretion system (T3SS) and six effectors, including the essential translocated intimin receptor (Tir). Seventeen additional effectors are encoded by genes located outside the LEE, in insertion elements and prophages. Here, using a stepwise approach, we generated an EPEC mutant lacking the entire effector genes (EPEC0) and intermediate mutants. We show that EPEC0 contains a functional T3SS. An EPEC mutant expressing intimin but lacking all the LEE effectors but Tir (EPEC1) was able to trigger robust actin polymerization in HeLa cells and mucin-producing intestinal LS174T cells. However, EPEC1 was unable to form A/E lesions on human intestinal in vitro organ cultures (IVOC). Screening the intermediate mutants for genes involved in A/E lesion formation on IVOC revealed that strains lacking non-LEE effector/s have a marginal ability to form A/E lesions. Furthermore, we found that Efa1/LifA proteins are important for A/E lesion formation efficiency in EPEC strains lacking multiple effectors. Taken together, these results demonstrate the intricate relationships between T3SS effectors and the essential role non-LEE effectors play in A/E lesion formation on mucosal surfaces

‘Central London under siege’: Diaspora, ‘race’ and the right to the (global) city

Drawing upon an ethnography of recent Congolese diasporic protests in central London, this article pays attention to the traversal histories of ‘race’ and the postcolonial dynamics that precede the emergence of a contemporary diasporic ‘right to the city’ movement. The authors critically engage with Henri Lefebvre’s ‘right to the city’ as a way of explaining how the urban is not only the site but also, increasingly, a stake in urban protests. In doing so the authors relocate urban centrality – its meaning, symbolic power and heuristic status in protests – in a context where activists’ claims are not restricted to one city or, simply, the political present. Rather, protestors talk about making geopolitical connections between local and global scales and contemporary and historical injustices. Drawing upon Simone’s notion of ‘black urbanism’, the authors claim to enrich Lefebvre’s original formulation by unpacking the complex performative dimensions of protest as they intersect with race and, more specifically, blackness and postcolonialism. It is concluded that activists’ experience is fundamentally ambivalent; they are at once enchanted and disenchanted with protest in central London