424 research outputs found
The average specific forced radiation wave impedance of a finite rectangular panel
The average specific forced radiation wave impedance of a finite rectangular panel is of importance for the prediction of both sound insulation and sound absorption. In 1982, Thomasson published numerical calculations of the average specific forced radiation wave impedance of a square of side length 2e for wave number k in half octave steps of ke from 0.25 to 64. Thomasson's calculations were for the case when the forced bending wave number kb was less than or equal to k. Thomasson also published approximate formulas for values of ke above and below the published results. This paper combines Thomasson's high and low frequency formulas and compares this combined formula with Thomasson's numerical calculations. The real part of the approximate formula is between 0.7 dB higher and -1 dB lower than the numerical calculations. The imaginary part of the approximate formula is between 2.3 dB higher and -2.6 dB lower than the numerical calculations. This paper also gives approximate formulas for the case when kb is greater than or equal to k. The differences are between 0.8 and -1.2 dB for the imaginary part and between 6.2 and -2.4 dB for the real part
The acoustic radiation impedance of a rectangular panel
This paper extends the definition of the one sided radiation impedance of a panel mounted in an infinite rigid baffle which was previously used by the authors so that it can be applied to all transverse velocity wave types on the panel rather than just to the possibly forced travelling plane transverse velocity waves considered previously by the authors. For the case of travelling plane waves on a rectangular panel with anechoic edge conditions, and for the case of standing waves on a rectangular panel with simply supported edge conditions, the equations resulting from one of the standard reductions from quadruple to double integrals are given. These double integral equations can be reduced to single integral equations, but the versions of these equations given in the literature did not always converge when used with adaptive integral routines and were sometimes slower than the double integral versions. This is because the terms in the integrands in the existing equations have singularities. Although these singularities cancel, they caused problems for the adaptive integral routines. This paper rewrites these equations in a form which removes the singularities and enables the integrals in these equations to be evaluated with adaptive integral routines. Approximate equations for the azimuthally averaged one sided radiation impedance of a rectangular panel mounted in an infinite baffle are given for all the cases considered in this paper and the values produced by these equations are compared with numerical calculations
Approximate equations for the radiation impedance of a rectangular panel
The authors have previously published approximate formulae for the average one sided specific radiation wave impedance of a finite rectangular panel mounted in a rigid infinite baffle. The panel's transverse vibration was due to a (possibly forced) two dimensional bending plane wave propagating in the panel without reflection at the edges of the panel. The average was over all the surface area of the panel and over all possible azimuthal angles of propagation direction. The radiation from waves propagating in different directions was assumed to be uncorrelated. These approximate formulae were derived from the 1982 research of Thomasson whose approximate formulae only covered the high and low frequency regions and not the mid frequency region. This paper presents more accurate versions of some of the approximate formulae. When the bending wave number is larger than the wave number of sound, the real part of the impedance is smaller than that for the case studied by Maidanik and Leppington. This is because correlated reflections are not included the case analyzed in this paper. When the bending wave number is smaller than or equals the wave number of sound, the real part of the impedance is the same for both cases
Approximate formulae for the average one sided specific radiation wave impedance of a finite rectangular panel
The authors have previously published approximate formulae for the average one sided specific radiation wave impedance of a finite rectangular panel mounted in a rigid infinite baffle. The panel's transverse vibration was due to a (possibly forced) two dimensional bending plane wave propagating in the panel without reflection at the edges of the panel. The average was over all the surface area of the panel and over all possible azimuthal angles of propagation direction. The radiation from waves propagating in different directions was assumed to be uncorrelated. These approximate formulae were derived from the 1982 research of Thomasson whose approximate formulae only covered the high and low frequency regions and not the mid frequency region. This paper presents more accurate versions of some of the approximate formulae. When the bending wave number is larger than the wave number of sound, the real part of the impedance is smaller than that for the case studied by Maidanik and Leppington. This is because correlated reflections are not included the case analyzed in this paper. When the bending wave number is smaller than or equals the wave number of sound, the real part of the impedance is the same for both cases
A discrete slug population model determined by egg production
Slugs are significant pests in agriculture (as well as a nuisance to gardeners), and it is therefore important to understand their population dynamics for the construction of efficient and effective control measures. Differential equation models of slug populations require the inclusion of large (variable) temporal delays, and strong seasonal forcing results in a non-autonomous system. This renders such models open to only a limited amount of rigorous analysis. In this paper, we derive a novel batch model based purely upon the quantity of eggs produced at different times of the year. This model is open to considerable reduction; from the resulting two variable discrete-time system it is possible to reconstruct the dynamics of the full population across the year and give conditions for extinction or global stability and persistence. Furthermore, the steady state temporal population distribution displays qualitatively different behavior with only small changes in the survival probability of slugs. The model demonstrates how small variations in the favorability of different years may result in widely different slug population fluctuations between consecutive years, and is in good agreement with field data
Glutathione-s-transferase pi expression in leukaemia: a comparative analysis with mdr-1 data.
Drug resistance in haemopoietic cells may be partly related to the expression of the glutathione-s-transferase (GST) pi and mdr-1 genes. We have used RNA slot blotting techniques to investigate the expression of GST pi in peripheral blood and bone marrow of eleven normal subjects, nine patients with myelodysplastic syndrome (MDS), eighteen patients with acute myeloblastic leukaemia (AML), and thirty-two patients with chronic lymphocyte leukaemia (CLL). We found increased expression of GST pi in 8 of 9 MDS, (7 peripheral blood, 1 bone marrow) 12 of 18 AML (5 peripheral blood, 7 bone marrow; 4 of 5 untreated, 1 of 5 secondary, 7 of 11 relapse or refractory) and in the peripheral blood of 24 of 32 CLL (3 of 7 untreated, 21 of 25 treated) relative to normal controls. Increased expression of GST pi can occur at any stage of disease and shows no clear relation to mdr-1 expression except, possibly, in CLL. In 3 AML patients GST pi transcript levels were the same or lower on relapse compared to presentation. Upregulation of the GST pi gene could not be demonstrated in 2 CLL patients in response to treatment with intermittent chlorambucil
Probing the Magnetized Interstellar Medium Surrounding the Planetary Nebula Sh 2-216
We present 1420 MHz polarization images of a 2.5 X 2.5 degree region around
the planetary nebula (PN) Sh 2-216. The images are taken from the Canadian
Galactic Plane Survey (CGPS). An arc of low polarized intensity appears
prominently in the north-east portion of the visible disk of Sh 2-216,
coincident with the optically identified interaction region between the PN and
the interstellar medium (ISM). The arc contains structural variations down to
the ~1 arcminute resolution limit in both polarized intensity and polarization
angle. Several polarization-angle "knots" appear along the arc. By comparison
of the polarization angles at the centers of the knots and the mean
polarization angle outside Sh 2-216, we estimate the rotation measure (RM)
through the knots to be -43 +/- 10 rad/m^2. Using this estimate for the RM and
an estimate of the electron density in the shell of Sh 2-216, we derive a
line-of-sight magnetic field in the interaction region of 5.0 +/- 2.0 microG.
We believe it more likely the observed magnetic field is interstellar than
stellar, though we cannot completely dismiss the latter possibility. We
interpret our observations via a simple model which describes the ISM magnetic
field around Sh 2-216, and comment on the potential use of old PNe as probes of
the magnetized ISM.Comment: 25 pages, 4 figures. Accepted for publication in the Astrophysical
Journa
New Evidence for Mass Loss from delta Cephei from HI 21-cm Line Observations
Recently published Spitzer observations of the classical Cepheid archetype
delta Cephei revealed an extended dusty nebula surrounding this star and its
hot companion. The infrared emission resembles a bow shock aligned with the
direction of space motion of the star, indicating that delta Cep is undergoing
mass-loss through a stellar wind. Here we report HI 21-cm line observations
with the VLA to search for neutral atomic hydrogen associated with this wind.
Our VLA data reveal a spatially extended HI nebula (~13' or 1 pc across)
surrounding the position of delta Cep. The nebula has a head-tail morphology,
consistent with circumstellar ejecta shaped by the interaction between a
stellar wind and the ISM. We directly measure a mass of circumstellar hydrogen
M_HI\approx0.07M_odot, although the total HI mass may be larger. The HI data
imply a stellar wind with an outflow velocity V_o=35.6\pm1.2 km/s and a
mass-loss rate of M_dot=(1.0\pm0.8)x10**-6 M_dot/yr. We have computed
theoretical evolutionary tracks that include mass loss across the instability
strip and show that a mass-loss rate of this magnitude, sustained over the
preceding Cepheid lifetime of delta Cep, could be sufficient to resolve a
significant fraction of the discrepancy between the pulsation and evolutionary
masses for this star. (abridged)Comment: ApJ, in press (January 1, 2012). Version with full resolution figures
available at
http://www.haystack.mit.edu/hay/staff/lmatthew/matthews_deltaCep.pd
The specific forced radiation wave impedance of a finite rectangular panel excited by a plane sound wave
The average specific forced radiation wave impedance of a finite rectangular panel, excited by a plane sound wave incident at a particular angle of incidence, is of importance for the prediction of both sound insulation and sound absorption. In 1982, Thomasson published numerical calculations of the average specific forced radiation wave impedance of a square of side length 2e for wave number k for values of ke in half octave steps from 0.25 to 64. Thomasson also published approximate formulae for values of ke above and below the published results. This paper combines Thomasson's high and low frequency formulae and compares this combined formula with Thomasson's numerical calculations. The real part of the approximate formula is between 0.7 dB higher and -1 dB lower than the numerical calculations. The imaginary part of the approximate formula is between 2.3 dB higher and - 2.6 dB lower than the numerical calculations. These extreme differences occur in the region of ke equals 2. However the imaginary part also has a difference of 1.7 dB for ke equals 64 at an angle of incidence of the forcing wave of 60 degrees relative to the normal to the square panel. An approximate formula for the real part developed previously by Davy is between 0.4 dB higher and -0.6 dB lower than Thomasson's numerical calculations. Thus it is in slightly better agreement with Thomasson's numerical calculations than the formula obtained by combining Thomasson's high and low frequency approximations. The imaginary specific radiation impedance of a rigid disk of equal area to a square and vibrating in phase gives a good approximation, up to ke equals 5, to the imaginary part of the specific forced radiation impedance of a square which has been excited by a plane wave incident normally to the square
Glutathione S-transferase isoenzymes in human tumours and tumour derived cell lines.
An increasing body of evidence indicates that glutathione S-transferases play a role in the intrinsic and acquired resistance of tumours to anticancer drugs. In view of the wide use of tumour cell lines to understand the factors which confer either sensitivity or resistance to chemotherapeutic agents we have determined glutathione S-transferase (GST) activity and isozyme composition in nine human cell lines. These data have been compared with the values obtained in solid tumours. In most cases overall GST activity was higher in the tumours than in the cell lines. This was most pronounced for the breast tumour samples relative to MCF7 cell line. The pi class GST subunit was present at similar concentration in the cell lines and the tumours, and in most cases was the most abundant subunit present. The alpha and mu class GST were expressed in most of the cell lines but at much lower concentration than the pi class subunit. Also considerable variability particularly in the expression of the mu subunits was observed. This was also the case for the expression of these subunits in the solid tumour samples. The levels of these GSTs (when expressed) in the solid tumours was invariably higher than that observed in the cell lines. There are therefore several similarities but also some significant differences in GST expression in solid tumours and cell lines. Whether the differences are because expression is lost during the generation of the cell lines or whether it reflects the individuality of human tumours remains to be clearly established
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