1,627 research outputs found
The density of seawater solutions at one atmosphere as a function of temperature and salinity
The relative density (d – d0) of diluted and evaporated standard seawater solutions have been determined at one atmosphere with a magnetic float densimeter and a suspension balance from 0.5 to 40‰ salinity and 0 to 40°C…
Performance of a Self-Paced Brain Computer Interface on Data Contaminated with Eye-Movement Artifacts and on Data Recorded in a Subsequent Session
The performance of a specific self-paced BCI (SBCI) is investigated using two different datasets to determine its suitability for using online: (1) data contaminated with large-amplitude eye movements, and (2) data recorded in a session subsequent to the original sessions used to design the system. No part of the data was rejected in the subsequent session. Therefore, this dataset can be regarded as a “pseudo-online” test set. The SBCI under investigation uses features extracted from three specific neurological phenomena. Each of these neurological phenomena belongs to a different frequency band. Since many prominent artifacts are either of mostly low-frequency (e.g., eye movements) or mostly high-frequency nature (e.g., muscle movements), it is expected that the system shows a fairly robust performance over artifact-contaminated data. Analysis of the data of four participants using epochs contaminated with large-amplitude eye-movement artifacts shows that the system's performance deteriorates only slightly. Furthermore, the system's performance during the session subsequent to the original sessions remained largely the same as in the original sessions for three out of the four participants. This moderate drop in performance can be considered tolerable, since allowing artifact-contaminated data to be used as inputs makes the system available for users at ALL times
A Self-Paced Two-State Mental Task-Based Brain-Computer Interface with Few EEG Channels
A self-paced brain-computer interface (BCI) system that is activated by mental tasks is introduced. The BCI’s output has two operational states, the active state and the inactive state, and is activated by designated mental tasks performed by the user. The BCI could be operated using several EEG brain electrodes (channels) or only few (i.e., five or seven channels) at a small loss in performance. The performance is evaluated on a dataset we have collected from four subjects while performing one of the four different mental tasks. The dataset contains the signals of 29 EEG electrodes distributed over the scalp. The five and seven highly discriminatory channels are selected using two different methods proposed in the paper. The signal processing structure of the interface is computationally simple. The features used are the scalar autoregressive coefficients. Classification is based on the quadratic discriminant analysis. Model selection and testing procedures are accomplished via cross-validation. The results are highly promising in terms of the rates of false and true positives. The false-positive rates reach zero, while the true-positive rates are sufficiently high, i.e., 54.60 and 59.98% for the 5-channel and 7-channel systems, respectively
3,4,5-Trichloroaniline Nephrotoxicity in Vitro: Potential Role of Free Radicals and Renal Biotransformation
Chloroanilines are widely used in the manufacture of drugs, pesticides and industrial intermediates. Among the trichloroanilines, 3,4,5-trichloroaniline (TCA) is the most potent nephrotoxicant in vivo. The purpose of this study was to examine the nephrotoxic potential of TCA in vitro and to determine if renal biotransformation and/or free radicals contributed to TCA cytotoxicity using isolated renal cortical cells (IRCC) from male Fischer 344 rats as the animal model. IRCC (~4 million cells/mL; 3 mL) were incubated with TCA (0, 0.1, 0.25, 0.5 or 1.0 mM) for 60–120 min. In some experiments, IRCC were pretreated with an antioxidant or a cytochrome P450 (CYP), flavin monooxygenase (FMO), cyclooxygenase or peroxidase inhibitor prior to incubation with dimethyl sulfoxide (control) or TCA (0.5 mM) for 120 min. At 60 min, TCA did not induce cytotoxicity, but induced cytotoxicity as early as 90 min with 0.5 mM or higher TCA and at 120 min with 0.1 mM or higher TCA, as evidenced by increased lactate dehydrogenase (LDH) release. Pretreatment with the CYP inhibitor piperonyl butoxide, the cyclooxygenase inhibitor indomethacin or the peroxidase inhibitor mercaptosuccinate attenuated TCA cytotoxicity, while pretreatment with FMO inhibitors or the CYP inhibitor metyrapone had no effect on TCA nephrotoxicity. Pretreatment with an antioxidant (α-tocopherol, glutathione, ascorbate or N-acetyl-L-cysteine) also reduced or completely blocked TCA cytotoxicity. These results indicate that TCA is directly nephrotoxic to IRCC in a time and concentration dependent manner. Bioactivation of TCA to toxic metabolites by CYP, cyclooxygenase and/or peroxidase contributes to the mechanism of TCA nephrotoxicity. Lastly, free radicals play a role in TCA cytotoxicity, although the exact nature of the origin of these radicals remains to be determined
Towards Development of a 3-State Self-Paced Brain-Computer Interface
Most existing brain-computer interfaces (BCIs) detect specific mental activity in a so-called synchronous paradigm. Unlike synchronous systems which are operational at specific system-defined periods, self-paced (asynchronous) interfaces have the advantage of being operational at all times. The low-frequency asynchronous switch design (LF-ASD) is a 2-state self-paced BCI that detects the presence of a specific finger movement in the ongoing EEG. Recent evaluations of the 2-state LF-ASD show an average true positive rate of 41% at the fixed false positive rate of 1%. This paper proposes two designs for a 3-state self-paced BCI that is capable of handling idle brain state. The two proposed designs aim at detecting right- and left-hand extensions from the ongoing EEG. They are formed of two consecutive detectors. The first detects the presence of a right- or a left-hand movement and the second classifies the detected movement as a right or a left one. In an offline analysis of the EEG data collected from four able-bodied individuals, the 3-state brain-computer interface shows a comparable performance with a 2-state system and significant performance improvement if used as a 2-state BCI, that is, in detecting the presence of a right- or a left-hand movement (regardless of the type of movement). It has an average true positive rate of 37.5% and 42.8% (at false positives rate of 1%) in detecting right- and left-hand extensions, respectively, in the context of a 3-state self-paced BCI and average detection rate of 58.1% (at false positive rate of 1%) in the context of a 2-state self-paced BCI
The JCMT Gould Belt Survey: Evidence for radiative heating in Serpens MWC 297 and its influence on local star formation
We present SCUBA-2 450micron and 850micron observations of the Serpens MWC
297 region, part of the JCMT Gould Belt Survey of nearby star-forming regions.
Simulations suggest that radiative feedback influences the star-formation
process and we investigate observational evidence for this by constructing
temperature maps. Maps are derived from the ratio of SCUBA-2 fluxes and a two
component model of the JCMT beam for a fixed dust opacity spectral index of
beta = 1.8. Within 40 of the B1.5Ve Herbig star MWC 297, the submillimetre
fluxes are contaminated by free-free emission with a spectral index of
1.03+-0.02, consistent with an ultra-compact HII region and polar winds/jets.
Contamination accounts for 73+-5 per cent and 82+-4 per cent of peak flux at
450micron and 850micron respectively. The residual thermal disk of the star is
almost undetectable at these wavelengths. Young Stellar Objects are confirmed
where SCUBA-2 850micron clumps identified by the fellwalker algorithm coincide
with Spitzer Gould Belt Survey detections. We identify 23 objects and use Tbol
to classify nine YSOs with masses 0.09 to 5.1 Msun. We find two Class 0, one
Class 0/I, three Class I and three Class II sources. The mean temperature is
15+-2K for the nine YSOs and 32+-4K for the 14 starless clumps. We observe a
starless clump with an abnormally high mean temperature of 46+-2K and conclude
that it is radiatively heated by the star MWC 297. Jeans stability provides
evidence that radiative heating by the star MWC 297 may be suppressing clump
collapse.Comment: 24 pages, 13 figures, 7 table
How Close Do We Live to Water? A Global Analysis of Population Distance to Freshwater Bodies
Traditionally, people have inhabited places with ready access to fresh water.
Today, over 50% of the global population lives in urban areas, and water
can be directed via tens of kilometres of pipelines. Still, however, a large
part of the world's population is directly dependent on access to natural
freshwater sources. So how are inhabited places related to the location of
freshwater bodies today? We present a high-resolution global analysis of how
close present-day populations live to surface freshwater. We aim to increase the
understanding of the relationship between inhabited places, distance to surface
freshwater bodies, and climatic characteristics in different climate zones and
administrative regions. Our results show that over 50% of the
world's population lives closer than 3 km to a surface freshwater body, and
only 10% of the population lives further than 10 km away. There are,
however, remarkable differences between administrative regions and climatic
zones. Populations in Australia, Asia, and Europe live closest to water.
Although populations in arid zones live furthest away from freshwater bodies in
absolute terms, relatively speaking they live closest to water considering the
limited number of freshwater bodies in those areas. Population distributions in
arid zones show statistically significant relationships with a combination of
climatic factors and distance to water, whilst in other zones there is no
statistically significant relationship with distance to water. Global studies on
development and climate adaptation can benefit from an improved understanding of
these relationships between human populations and the distance to fresh
water
Tests of model of color reconnection and a search for glueballs using gluon jets with a rapidity gap
Gluon jets with a mean energy of 22 GeV and purity of 95% are selected from
hadronic Z0 decay events produced in e+e- annihilations. A subsample of these
jets is identified which exhibits a large gap in the rapidity distribution of
particles within the jet. After imposing the requirement of a rapidity gap, the
gluon jet purity is 86%. These jets are observed to demonstrate a high degree
of sensitivity to the presence of color reconnection, i.e. higher order QCD
processes affecting the underlying color structure. We use our data to test
three QCD models which include a simulation of color reconnection: one in the
Ariadne Monte Carlo, one in the Herwig Monte Carlo, and the other by Rathsman
in the Pythia Monte Carlo. We find the Rathsman and Ariadne color reconnection
models can describe our gluon jet measurements only if very large values are
used for the cutoff parameters which serve to terminate the parton showers, and
that the description of inclusive Z0 data is significantly degraded in this
case. We conclude that color reconnection as implemented by these two models is
disfavored. The signal from the Herwig color reconnection model is less clear
and we do not obtain a definite conclusion concerning this model. In a separate
study, we follow recent theoretical suggestions and search for glueball-like
objects in the leading part of the gluon jets. No clear evidence is observed
for these objects.Comment: 42 pages, 18 figure
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