628 research outputs found
Symmetries of the Kac-Peterson Modular Matrices of Affine Algebras
The characters of nontwisted affine algebras at fixed level define
in a natural way a representation of the modular group . The
matrices in the image are called the Kac-Peterson modular
matrices, and describe the modular behaviour of the characters. In this paper
we consider all levels of , and for
each of these find all permutations of the highest weights which commute with
the corresponding Kac-Peterson matrices. This problem is equivalent to the
classification of automorphism invariants of conformal field theories, and its
solution, especially considering its simplicity, is a major step toward the
classification of all Wess-Zumino-Witten conformal field theories.Comment: 16 pp, plain te
Aging in a topological spin glass
We have examined the nonconventional spin glass phase of the 2-dimensional
kagome antiferromagnet (H_3 O) Fe_3 (SO_4)_2 (OH)_6 by means of ac and dc
magnetic measurements. The frequency dependence of the ac susceptibility peak
is characteristic of a critical slowing down at Tg ~ 18K. At fixed temperature
below Tg, aging effects are found which obey the same scaling law as in spin
glasses or polymers. However, in clear contrast with conventional spin glasses,
aging is remarkably insensitive to temperature changes. This particular type of
dynamics is discussed in relation with theoretical predictions for highly
frustrated non-disordered systems.Comment: 4 pages, 4 figure
On the Classification of Diagonal Coset Modular Invariants
We relate in a novel way the modular matrices of GKO diagonal cosets without
fixed points to those of WZNW tensor products. Using this we classify all
modular invariant partition functions of
for all positive integer level , and for all and infinitely many (in fact, for
each a positive density of ). Of all these classifications, only that
for had been known. Our lists include many
new invariants.Comment: 24 pp (plain tex
Structural dissection of two redox proteins from the shipworm symbiont Teredinibacter turnerae
\ua9 2024 International Union of Crystallography. All rights reserved.The discovery of lytic polysaccharide monooxygenases (LPMOs), a family of copper-dependent enzymes that play a major role in polysaccharide degradation, has revealed the importance of oxidoreductases in the biological utilization of biomass. In fungi, a range of redox proteins have been implicated as working in harness with LPMOs to bring about polysaccharide oxidation. In bacteria, less is known about the interplay between redox proteins and LPMOs, or how the interaction between the two contributes to polysaccharide degradation. We therefore set out to characterize two previously unstudied proteins from the shipworm symbiont Teredinibacter turnerae that were initially identified by the presence of carbohydrate binding domains appended to uncharacterized domains with probable redox functions. Here, X-ray crystal structures of several domains from these proteins are presented together with initial efforts to characterize their functions. The analysis suggests that the target proteins are unlikely to function as LPMO electron donors, raising new questions as to the potential redox functions that these large extracellular multi-haem-containing c-type cytochromes may perform in these bacteria
Continuum theory of partially fluidized granular flows
A continuum theory of partially fluidized granular flows is developed. The
theory is based on a combination of the equations for the flow velocity and
shear stresses coupled with the order parameter equation which describes the
transition between flowing and static components of the granular system. We
apply this theory to several important granular problems: avalanche flow in
deep and shallow inclined layers, rotating drums and shear granular flows
between two plates. We carry out quantitative comparisons between the theory
and experiment.Comment: 28 pages, 23 figures, submitted to Phys. Rev.
Preparation, structural characterisation and antibacterial properties of Ga-doped sol-gel phosphate-based glass
A sol-gel preparation of Ga-doped phosphate-based glass with potential application in antimicrobial devices has been developed. Samples of composition (CaO)(0.30)(Na2O)(0.20-x) (Ga2O3) (x) (P2O5)(0.50) where x = 0 and 0.03 were prepared, and the structure and properties of the gallium-doped sample compared with those of the sample containing no gallium. Analysis of the P-31 MAS NMR data demonstrated that addition of gallium to the sol-gel reaction increases the connectivity of the phosphate network at the expense of hydroxyl groups. This premise is supported by the results of the elemental analysis, which showed that the gallium-free sample contains significantly more hydrogen and by FTIR spectroscopy, which revealed a higher concentration of -OH groups in that sample. Ga K-edge extended X-ray absorption fine structure and X-ray absorption near-edge structure data revealed that the gallium ions are coordinated by six oxygen atoms. In agreement with the X-ray absorption data, the high-energy XRD results also suggest that the Ga3+ ions are octahedrally coordinated with respect to oxygen. Antimicrobial studies demonstrated that the sample containing Ga3+ ions had significant activity against Staphylococcus aureus compared to the control
Finite Element Analysis to model ischemia experienced in the development of device related pressure ulcers.
Pressure ulcers are a common occurrence of damage to skin. Severity ranges from slightly
discoloured skin to full thickness tissue damage which can be fatal in some cases. Engineering effort,
typically developing computational models had made significant progress in the understanding and
demonstration of the formation mechanism of pressure ulcers with the aetiology of excessive stress
however relatively limited attempts had been made to develop relevant models for pressure ulcers
caused by ischemia. The aim of this paper is to present evidence of a computational model
developed to simulate ischemic pressure ulcer formation and demonstrate the established
relationship between the computational data and the acquired clinically relevant experimental data
by utilising laser Doppler velocimetry. The application of the presented computational model and
the established relationship allows the evaluation of the effect of a mechanical loading to the
cutaneous blood flow velocity which is a step closing to understand and evaluate a mechanical load
to the formation of pressure ulcers caused by ischemia
A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13).
BACKGROUND: Rhinovirus infection is a major cause of asthma exacerbations. OBJECTIVES: We studied nasal and bronchial mucosal inflammatory responses during experimental rhinovirus-induced asthma exacerbations. METHODS: We used nasosorption on days 0, 2-5 and 7 and bronchosorption at baseline and day 4 to sample mucosal lining fluid to investigate airway mucosal responses to rhinovirus infection in patients with allergic asthma (n=28) and healthy non-atopic controls (n=11), by using a synthetic absorptive matrix and measuring levels of 34 cytokines and chemokines using a sensitive multiplex assay. RESULTS: Following rhinovirus infection asthmatics developed more upper and lower respiratory symptoms and lower peak expiratory flows compared to controls (all P<0.05). Asthmatics also developed higher nasal lining fluid levels of an anti-viral pathway (including IFN-γ, IFN-λ/IL-29, CXCL11/ITAC, CXCL10/IP10 and IL-15) and a type 2 inflammatory pathway (IL-4, IL-5, IL-13, CCL17/TARC, CCL11/eotaxin, CCL26/eotaxin-3) (area under curve day 0-7, all P<0.05). Nasal IL-5 and IL-13 were higher in asthmatics at day 0 (P<0.01) and levels increased by days 3 and 4 (P<0.01). A hierarchical correlation matrix of 24 nasal lining fluid cytokine and chemokine levels over 7days demonstrated expression of distinct interferon-related and type 2 pathways in asthmatics. In asthmatics IFN-γ, CXCL10/IP10, CXCL11/ITAC, IL-15 and IL-5 increased in bronchial lining fluid following viral infection (all P<0.05). CONCLUSIONS: Precision sampling of mucosal lining fluid identifies robust interferon and type 2 responses in the upper and lower airways of asthmatics during an asthma exacerbation. Nasosorption and bronchosorption have potential to define asthma endotypes in stable disease and at exacerbation
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