444 research outputs found
Phylogenetic placement and the timing of diversification in Australia's endemic Vachellia (Caesalpinioideae, Mimosoid Clade, Fabaceae) species
The genus Vachellia Wight & Arn. has a pantropical distribution, with species being distributed through Africa, the Americas, Asia and Australia. The relationships among the lineages from Africa and America are well understood, but the phylogenetic placement and evolutionary origins of the Australian species of Vachellia are not known. We, therefore, sequenced four plastid genes from representatives of each of the nine Australian species of Vachellia, and used Bayesian inference to assess the phylogenetic placement of these lineages, and a relaxed molecular clock to assess the timing of diversification. The Australian species of Vachellia form a well-supported monophyletic clade, with molecular-dating analysis suggesting a single dispersal into Australia 6.5 million years ago (95% range 13.9-2.7 million years ago). Diversification of the Australian clade commenced more recently, c. 3.1 million years ago (95% range 9.2-1.2 million years ago), perhaps driven by the increased aridification of Australia at this time. The closest relatives to the Australian Vachellia were not from the Malesian bioregion, suggesting either a long-distance dispersal from Africa, or two separate migrations through Asia. These results not only improve our understanding of the biogeography of Vachellia species, but also have significant implications for the biological control of invasive Vachellia species in Australia. © 2020 CSIRO
Quantifying fat replacement of muscle by quantitative MRI in muscular dystrophy
Imaging- and therapeutic targets in neoplastic and musculoskeletal inflammatory diseas
Resolutions of C^n/Z_n Orbifolds, their U(1) Bundles, and Applications to String Model Building
We describe blowups of C^n/Z_n orbifolds as complex line bundles over
CP^{n-1}. We construct some gauge bundles on these resolutions. Apart from the
standard embedding, we describe U(1) bundles and an SU(n-1) bundle. Both
blowups and their gauge bundles are given explicitly. We investigate ten
dimensional SO(32) super Yang-Mills theory coupled to supergravity on these
backgrounds. The integrated Bianchi identity implies that there are only a
finite number of U(1) bundle models. We describe how the orbifold gauge shift
vector can be read off from the gauge background. In this way we can assert
that in the blow down limit these models correspond to heterotic C^2/Z_2 and
C^3/Z_3 orbifold models. (Only the Z_3 model with unbroken gauge group SO(32)
cannot be reconstructed in blowup without torsion.) This is confirmed by
computing the charged chiral spectra on the resolutions. The construction of
these blowup models implies that the mismatch between type-I and heterotic
models on T^6/Z_3 does not signal a complication of S-duality, but rather a
problem of type-I model building itself: The standard type-I orbifold model
building only allows for a single model on this orbifold, while the blowup
models give five different models in blow down.Comment: 1+27 pages LaTeX, 2 figures, some typos correcte
Predicting the habitat suitability and distribution of two species of mound-building termites in Nigeria using bioclimatic and vegetation variables
Temperature is an important factor determining the abundance, distribution and diversity of termite species. Thus, termites are affected by changing climate and have to adopt different means of surviving in order to avoid extinction. Using termite occurrence data, bioclimatic variables and vegetation cover, we modelled and predicted the current and future habitat suitability for mound-building termites in Nigeria. Of the 19 bioclimatic variables and the vegetation index (NDVI) tested, only six were significant and eligible as predictors of habitat suitability for the mound-building termites Macrotermes subhyalinus and M. bellicosus. Under current climatic conditions (2022), the northwest, northeast and central regions are highly suitable for M. subhyalinus, while the distribution of M. bellicosus decreased in the North West, North East and in the Central region. However, regarding habitat suitability for the future (2050), there was a predicted range expansion into suitable areas for the two termite species. The increase in temperature due to global warming has an effect which can either result in migration or sometimes extinction of termite species within an ecosystem. Here, we have predicted habitat suitability for the two mound-building termite species under current and future climatic scenarios, and how the change in climatic variables would lead to an expansion in their range across Nigeria.The University of Pretoria, The South African National Research Foundation (NRF) Incentive Funding for Rated Researchers (IFRR), Y-Rated Research Grant, PI grant from South African Research Chair in Mathematical Methods in Bioengineering and Biosciences (M2B3), Alexander von Humboldt’s Georg Foster HERMES Experienced Research Fellowship, a University of Pretoria Postgraduate Bursary and the Nigerian Tertiary Education Trust Fund (TETFund).https://www.mdpi.com/journal/diversityhj2023Zoology and Entomolog
The neutron radii of Lead and neutron stars
A new relation between the neutron skin of a heavy nucleus and the radius of
a neutron star is proposed: the larger the neutron skin of the nucleus the
larger the radius of the star. Relativistic models that reproduce a variety of
ground-state observables can not determine uniquely the neutron skin of a heavy
nucleus. Thus, a large range of neutron skins is generated by supplementing the
models with nonlinear couplings between isoscalar and isovector mesons. We
illustrate how the correlation between the neutron skin and the radius of the
star can be used to place important constraints on the equation of state and
how it may help elucidate the existence of a phase transition in the interior
of the neutron star.Comment: 4 pages including 4 encapsulated postscript figure
Parity Violating Measurements of Neutron Densities
Parity violating electron nucleus scattering is a clean and powerful tool for
measuring the spatial distributions of neutrons in nuclei with unprecedented
accuracy. Parity violation arises from the interference of electromagnetic and
weak neutral amplitudes, and the of the Standard Model couples primarily
to neutrons at low . The data can be interpreted with as much confidence
as electromagnetic scattering. After briefly reviewing the present theoretical
and experimental knowledge of neutron densities, we discuss possible parity
violation measurements, their theoretical interpretation, and applications. The
experiments are feasible at existing facilities. We show that theoretical
corrections are either small or well understood, which makes the interpretation
clean. The quantitative relationship to atomic parity nonconservation
observables is examined, and we show that the electron scattering asymmetries
can be directly applied to atomic PNC because the observables have
approximately the same dependence on nuclear shape.Comment: 38 pages, 7 ps figures, very minor changes, submitted to Phys. Rev.
Cardiac xenotransplantation: Recent preclinical progress with 3-month median survival
ObjectivesTransplantation is limited by a lack of human organ donors. Organs derived from animals, most likely the pig, represent a potential solution to this problem. For the heart, 90-day median graft survival of life-supporting pig hearts transplanted to nonhuman primates has been considered a reasonable standard for entry into the clinical arena. Overcoming the immune barrier to successful cardiac xenotransplantation is most appropriately first explored with the non–life-supporting heterotopic model.MethodsWe performed a series of 7 heterotopic heart transplantations from CD46 transgenic pigs to baboons using a combination of therapeutic agents largely targeted at controlling the synthesis of anti-pig antibodies. Rituximab (anti-CD20) and Thymoglobulin (rabbit antithymocyte globulin [ATG]; SangStat Medical Corp, Fremont, Calif) were used as induction therapy. Baseline immunosuppression consisted of splenectomy, tacrolimus, sirolimus, steroids, and TPC (an anti-Gal antibody therapeutic). Rejection events were not treated.ResultsBy using Kaplan-Meier analysis, median graft survival was 96 days (range, 15–137 days; 95% confidence interval, 38–99 days). Only 2 grafts were lost as a result of rejection, as defined by cessation of graft palpation. There was no evidence of a consumptive coagulopathy, infectious complications were treatable, and no posttransplantation lymphoproliferative disorders occurred. No cellular infiltration was observed.ConclusionsThis study reports the longest median survival to date (96 days) of pig hearts transplanted heterotopically into baboons. Duplication of these results in the orthotopic life-supporting position could bring cardiac xenotransplantation to the threshold of clinical application
Neutrinoless double-beta decay and seesaw mechanism
From the standard seesaw mechanism of neutrino mass generation, which is
based on the assumption that the lepton number is violated at a large
(~10exp(+15) GeV) scale, follows that the neutrinoless double-beta decay is
ruled by the Majorana neutrino mass mechanism. Within this notion, for the
inverted neutrino-mass hierarchy we derive allowed ranges of half-lives of the
neutrinoless double-beta decay for nuclei of experimental interest with
different sets of nuclear matrix elements. The present-day results of the
calculation of the neutrinoless double-beta decay nuclear matrix elements are
briefly discussed. We argue that if neutrinoless double-beta decay will be
observed in future experiments sensitive to the effective Majorana mass in the
inverted mass hierarchy region, a comparison of the derived ranges with
measured half-lives will allow us to probe the standard seesaw mechanism
assuming that future cosmological data will establish the sum of neutrino
masses to be about 0.2 eV.Comment: Some changes in sections I, II, IV, and V; two new figures;
additional reference
Observational diagnostics of gas in protoplanetary disks
Protoplanetary disks are composed primarily of gas (99% of the mass).
Nevertheless, relatively few observational constraints exist for the gas in
disks. In this review, I discuss several observational diagnostics in the UV,
optical, near-IR, mid-IR, and (sub)-mm wavelengths that have been employed to
study the gas in the disks of young stellar objects. I concentrate in
diagnostics that probe the inner 20 AU of the disk, the region where planets
are expected to form. I discuss the potential and limitations of each gas
tracer and present prospects for future research.Comment: Review written for the proceedings of the conference "Origin and
Evolution of Planets 2008", Ascona, Switzerland, June 29 - July 4, 2008. Date
manuscript: October 2008. 17 Pages, 6 graphics, 134 reference
Measurement of and charged current inclusive cross sections and their ratio with the T2K off-axis near detector
We report a measurement of cross section and the first measurements of the cross section
and their ratio
at (anti-)neutrino energies below 1.5
GeV. We determine the single momentum bin cross section measurements, averaged
over the T2K -flux, for the detector target material (mainly
Carbon, Oxygen, Hydrogen and Copper) with phase space restricted laboratory
frame kinematics of 500 MeV/c. The
results are and $\sigma(\nu)=\left( 2.41\
\pm0.022{\rm{(stat.)}}\pm0.231{\rm (syst.)}\ \right)\times10^{-39}^{2}R\left(\frac{\sigma(\bar{\nu})}{\sigma(\nu)}\right)=
0.373\pm0.012{\rm (stat.)}\pm0.015{\rm (syst.)}$.Comment: 18 pages, 8 figure
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