Studies of high latitude current systems using MAGSAT vector data

The magnetic disturbance fields caused by global external current systems are considered with particular emphasis on improving the understanding of the physical processes which control high latitude current systems. Following processing the MAGSAT data were routinely plotted in the Universal Time (UT) format as well as in a polar plot format. The H'D'U' coordinate system, was adopted as the standard for representing the MAGSAT residual magnetic field vectors. A data file was generated and the TPOLAR computer code was developed to determine from the orbital elements, the time, latitude, and MLT of the extremum latitude of each transpolar segment of orbit. The precision of the vector data set from MAGSAT prompted an extended exploratory phase for data analysis procedures, modeling techniques and phenomenology

Studies of high latitude current systems using Magsat vector data

Disturbance fields caused by global external current systems are analyzed in order to gain an improved understanding of the phydical processes which control high latitude current systems and to increase the confidence level in the identification of internal field levels. The basic approach is to: (1) categorize the vector data by those physical parameters important for investigation of external current systems; (2) map the disturbances for appropriate conditions; (3) model the currents which might cause the mapped disturbances; and (4) correlate results with data from other sources. It is concluded that the Magsat data set appears to have remarkably high precision and quality and should permit major advances to be made in modeling current distribution at high latitudes in the ionosphere and magnetosphere

Direct radiocarbon dating of fish otoliths from mulloway (Argyrosomus japonicus) and black bream (Acanthopagrus butcheri) from Long Point, Coorong, South Australia

Accelerator Mass Spectrometry (AMS) radiocarbon dates (n=20) determined on fish otoliths from mulloway (Argyrosomus japonicus) and black bream (Acanthopagrus butcheri) are reported from five sites at Long Point, Coorong, South Australia. The dates range from 2938–2529 to 326–1 cal. BP, extending the known period of occupation of Long Point. Previous dating at the sites indicated intensive occupation of the area from 2455–2134 cal. BP. Results provide a detailed local chronology for the region, contributing to a more comprehensive understanding of Aboriginal use of Ngarrindjeri lands and waters. This study validates the use of fish otoliths for radiocarbon dating and reveals how dating different materials can result in different midden chronologies

G-Protein coupled receptors: structure and function in drug discovery

The G-protein coupled receptors (GPCRs) superfamily comprise similar proteins arranged into families or classes thus making it one of the largest in the mammalian genome. GPCRs take part in many vital physiological functions making them targets for numerous novel drugs. GPCRs share some distinctive features, such as the seven transmembrane domains, they also differ in the number of conserved residues in their transmembrane domain. Here we provide an introductory and accessible review detailing the computational advances in GPCR pharmacology and drug discovery. An overview is provided on family A-C GPCRs; their structural differences, GPCR signalling, allosteric binding and cooperativity. The dielectric constant (relative permittivity) of proteins is also discussed in the context of site-specific environmental effects

O- vs. N-protonation of 1-dimethylaminonaphthalene-8-ketones: formation of a peri N–C bond or a hydrogen bond to the pi-electron density of a carbonyl group

X-ray crystallography and solid-state NMR measurements show that protonation of a series of 1-dimethylaminonaphthalene-8-ketones leads either to O protonation with formation of a long N–C bond (1.637–1.669 Å) between peri groups, or to N protonation and formation of a hydrogen bond to the π surface of the carbonyl group, the latter occurring for the larger ketone groups (C(O)R, R = t-butyl and phenyl). Solid state 15N MAS NMR studies clearly differentiate the two series, with the former yielding significantly more deshielded resonances. This is accurately corroborated by DFT calculation of the relevant chemical shift parameters. In the parent ketones X-ray crystallography shows that the nitrogen lone pair is directed towards the carbonyl group in all cases

Pulp, Vol. 2 No. 1

This is the second issue of Pulp.https://scholarworks.sfasu.edu/pulp/1001/thumbnail.jp

Pulp, Vol. 2 No. 1

This is the second issue of Pulp.https://scholarworks.sfasu.edu/pulp/1001/thumbnail.jp