MR motility imaging in Crohn's disease improves lesion detection compared with standard MR imaging

Objective: To evaluate retrospectively in patients with Crohn's disease (CD) if magnetic resonance (MR) motility alterations correlate with CD typical lesions leading to an increased detection rate. Methods: Forty patients with histologically proven CD underwent MR enterography (MRE), including coronal cine sequences (cine MRE), in addition to the standard CD MR protocol. Two blinded readings were performed with and without cine MRE. Locations presenting motility alterations on the cine sequences were analysed on standard MRE for CD-related lesions. This was compared with a second reading using the standard clinical MRE protocol alone. Results: The number of lesions localised by cine MRE and identified on standard MRE compared with standard MRE alone were 35/24 for wall thickening (p = 0.002), 24/20 for stenoses (p = 0.05), 17/11 for wall layering (p = 0.02), 5/3 for mucosal ulcers (p = 0.02) and 21/17 for the comb sign (p = 0.05). Overall, cine MRE detected 35 more CD-specific findings than standard MRE alone (124/89; p = 0.007) and significantly more patients with CD-relevant MR findings (34/28; p = 0.03). Conclusion: CD lesions seem to be associated with motility changes and this leads to an increased lesion detection rate compared with standard-MRE imaging alon

Machine Translation Vs. Multilingual Dictionaries Assessing Two Strategies for the Topic Modeling of Multilingual Text Collections

The goal of this paper is to evaluate two methods for the topic modeling of multilingual document collections: (1) machine translation (MT), and (2) the coding of semantic concepts using a multilingual dictionary (MD) prior to topic modeling. We empirically assess the consequences of these approaches based on both a quantitative comparison of models and a qualitative validation of each method’s potentials and weaknesses. Our case study uses two text collections (of tweets and news articles) in three languages (English, Hebrew, Arabic), covering the ongoing local conflicts between Israeli authorities, settlers, and Palestinian Bedouins in the West Bank. We find that both methods produce a large share of equivalent topics, especially in the context of fairly homogenous news discourse, yet show limited but systematic differences when applied to highly heterogenous social media discourse. While the MD model delivers a more nuanced picture of conflict-related topics, it misses several more peripheral topics, especially those unrelated to the dictionary’s focus, which are picked up by the MT model. Our study is a first step toward instrument validation, indicating that both methods yield valid, comparable results, while method-specific differences remain

MR motility imaging in Crohn's disease improves lesion detection compared with standard MR imaging

To evaluate retrospectively in patients with Crohn's disease (CD) if magnetic resonance (MR) motility alterations correlate with CD typical lesions leading to an increased detection rate

Observation of bosonic condensation in a hybrid monolayer MoSe2-GaAs microcavity

C.S. acknowledges support by the ERC (Project unLiMIt-2D), and the DFG within the Project SCHN1376 3-1. The Würzburg group acknowledges support by the State of Bavaria. A.N. and E.C. acknowledge the support from the megagrant 14.Y26.31.0015 and Goszadanie no. 3.2614.2017/4.6 of the Ministry of Education and Science of Russian Federation. A.V.K. acknowledges the support from the St-Petersburg State University in framework of the project 11.34.2.2012. S.H. and A.V.K. are grateful for funding received within the EPSRC Hybrid Polaritonics programme grant (EP/M025330/1). S.K. acknowledges the European Commission for the H2020 Marie Skłodowska-Curie Actions fellowship (Topopolis). S.T acknowledges support from NSF DMR 1838443 and NSF DMR 1552220.Bosonic condensation belongs to the most intriguing phenomena in physics, and was mostly reserved for experiments with ultra-cold quantum gases. More recently, it became accessible in exciton-based solid-state systems at elevated temperatures. Here, we demonstrate bosonic condensation driven by excitons hosted in an atomically thin layer of MoSe2, strongly coupled to light in a solid-state resonator. The structure is operated in the regime of collective strong coupling between a Tamm-plasmon resonance, GaAs quantum well excitons, and two-dimensional excitons confined in the monolayer crystal. Polariton condensation in a monolayer crystal manifests by a superlinear increase of emission intensity from the hybrid polariton mode, its density-dependent blueshift, and a dramatic collapse of the emission linewidth, a hallmark of temporal coherence. Importantly, we observe a significant spin-polarization in the injected polariton condensate, a fingerprint for spin-valley locking in monolayer excitons. Our results pave the way towards highly nonlinear, coherent valleytronic devices and light sources.Publisher PDFPeer reviewe

Toward a Stronger Theoretical Grounding of Computational Communication Science: How Macro Frameworks Shape Our Research Agendas

Manuscript accepted for publication at the journal Computational Communication Researc