Flexible Photonic Cellulose Nanocrystal Films.

The fabrication of self-assembled cellulose nanocrystal (CNC) films of tunable photonic and mechanical properties using a facile, green approach is demonstrated. The combination of tunable flexibility and iridescence can dramatically expand CNC coating and film barrier capabilities for paints and coating applications, sustainable consumer packaging products, as well as effective templates for photonic and optoelectronic materials and structures.CelluForce Inc., Biotechnology and Biological Sciences Research Council (David Phillips fellowship (Grant ID: BB/K014617/1, 76933), European Research Council (Grant ID: ERC-2014-STG H2020 639088), Engineering and Physical Sciences Research Council (Grant ID: 1525292

Research data supporting Effect of thermal treatments on chiral nematic cellulose nanocrystal films

the dataset content is described in the associated pdf summary

Retrieving the Coassembly Pathway of Composite Cellulose Nanocrystal Photonic Films from their Angular Optical Response.

Aqueous suspensions of cellulose nanocrystals (CNCs) are known to self-assemble into a chiral nematic liquid crystalline phase, leading to solid-state nanostructured colored films upon solvent evaporation, even in the presence of templating agents. The angular optical response of these structures, and therefore their visual appearance, are completely determined by the spatial arrangement of the CNCs when the drying suspension undergoes a transition from a flowing and liquid crystalline state to a kinetically arrested state. Here, it is demonstrated how the angular response of the final film allows for retrieval of key physical properties and the chemical composition of the suspension at the onset of the kinetic arrest, thus capturing a snapshot of the past. To illustrate this methodology, a dynamically evolving sol-gel coassembly process is investigated by adding various amounts of organosilica precursor, namely, 1,2-bis(trimethoxysilyl)ethane. The influence of organosilica condensation on the kinetic arrest can be tracked and thus explains the angular response of the resulting films. The a posteriori and in situ approach is general; it can be applied to a variety of additives in CNC-based films and it allows access to key rheological information of the suspension without using any dedicated rheological technique.M.J.M. thanks NSERC for a Discovery Gran

Research data supporting "Retrieving the co-assembly pathway of composite cellulose nanocrystal photonic films from their angular optical response"

the Summary of the data is detailed in the provided document "OpenDataSummary.pdf" and ordered by the figures they contributed to, including for the Figures in Supporting Information.M.J.M. thanks NSERC for a Discovery Grant

Current characterization methods for cellulose nanomaterials

International audienc

The global burden of cancer attributable to risk factors, 2010-19 : a systematic analysis for the Global Burden of Disease Study 2019

Background Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. Findings Globally, in 2019, the risk factors included in this analysis accounted for 4.45 million (95% uncertainty interval 4.01-4.94) deaths and 105 million (95.0-116) DALYs for both sexes combined, representing 44.4% (41.3-48.4) of all cancer deaths and 42.0% (39.1-45.6) of all DALYs. There were 2.88 million (2.60-3.18) risk-attributable cancer deaths in males (50.6% [47.8-54.1] of all male cancer deaths) and 1.58 million (1.36-1.84) risk-attributable cancer deaths in females (36.3% [32.5-41.3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20.4% (12.6-28.4) and DALYs by 16.8% (8.8-25.0), with the greatest percentage increase in metabolic risks (34.7% [27.9-42.8] and 33.3% [25.8-42.0]). Interpretation The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden. Copyright (C) 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.Peer reviewe

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019

BACKGROUND: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. METHODS: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented. FINDINGS: Globally, in 2019, the risk factors included in this analysis accounted for 4·45 million (95% uncertainty interval 4·01–4·94) deaths and 105 million (95·0–116) DALYs for both sexes combined, representing 44·4% (41·3–48·4) of all cancer deaths and 42·0% (39·1–45·6) of all DALYs. There were 2·88 million (2·60–3·18) risk-attributable cancer deaths in males (50·6% [47·8–54·1] of all male cancer deaths) and 1·58 million (1·36–1·84) risk-attributable cancer deaths in females (36·3% [32·5–41·3] of all female cancer deaths). The leading risk factors at the most detailed level globally for risk-attributable cancer deaths and DALYs in 2019 for both sexes combined were smoking, followed by alcohol use and high BMI. Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings. From 2010 to 2019, global risk-attributable cancer deaths increased by 20·4% (12·6–28·4) and DALYs by 16·8% (8·8–25·0), with the greatest percentage increase in metabolic risks (34·7% [27·9–42·8] and 33·3% [25·8–42·0]). INTERPRETATION: The leading risk factors contributing to global cancer burden in 2019 were behavioural, whereas metabolic risk factors saw the largest increases between 2010 and 2019. Reducing exposure to these modifiable risk factors would decrease cancer mortality and DALY rates worldwide, and policies should be tailored appropriately to local cancer risk factor burden

Research data supporting “Flexible photonic cellulose nanocrystal films”

Original or unprocessed data is provided in support of the article “Flexible photonic cellulose nanocrystal films”. The data is structured into eight folders, each correlating to a specific data type presented in the published article. Folder 1: Fourier Transformed Infra-Red Spectroscopy (FT-IR) The data used to plot Figure 1b in the manuscript are provided (.xlsx and .pdf). They correspond to the FT-IR spectra of pure cellulose nanocrystals and cellulose nanocrystals with different surfactant loading, as per description. Folder 2: Scanning electron microscopy (SEM) Micrographs cellulose films cross-sections showing the chiral nematic arrangement of cellulose nanocrystals retained for all surfactant loadings are provided (.tif). The folder ‘Figure 2’ contains high magnification images, used for Figure 2 of the manuscript, the folder ‘Figure S6’ contains the images, used for Figure S6 of the supplementary information. Folder 3: Mechanical Tests The data used to plot the stress versus strain behaviour for different surfactant loading, Figure 4a in the manuscript, and different counter-ions, Figure 4b in the manuscript, are provided (.xlsx and .pdf). The folder contains also the original figures used for the insets, respectively with high surfactant loading, Figure 4a, and intermediate surfactant loading, Figure 4b. Folder 4: Polarised optical microscopy (POM) The polarised optical microscopy images (.png) used in Figures 3 of the manuscript and in Figure S5 of the supplementary information are provided into their corresponding folders. The scalebar is included in each folder for reference. The folder ‘Figure 3 contains also the reflectivity spectra (.mat) used to plot the graph in Figure 3b. The films were imaged under with polarizing filters, as described in the Methods section of the manuscript. Folder 5: Nuclear Magnetic Resonance (NMR) The NRM spectra used for Figure S1 of the supplementary information are reported with their corresponding labels (.jpg and .docx). Folder 6: Powder X-Ray Diffraction (PXRD) The data used to plot the graph in Figure S2 of the supplementary information are provided (.xlsx and .pdf). Folder 7: Suspension Stability The original photographs (.jpg) of vials containing cellulose nanocrystal suspensions in different solvents and corresponding polarity indexes (.txt and .docx) used for Figure S3 of the supplementary information are provided. Folder 8: Atomic force microscopy (AFM) This data used for Figure S4 of the supplementary information are provided. The micrograph reported in Figure S4 is provided (.mi and .png). Micrographs of the individual cellulose nanocrystals (.mi and .png) and the histograms that illustrate the distribution of lengths and heights determined from this sample (.png) Original .mi data that can be opened with the free software Gwyddion are provided in the subfolder ‘size distirbution’. The length and height size distributions were extracted from the .mi figures using Matlab.BBSRC David Phillips fellowship [BB/K014617/1] [76933], European Research Council [ERC-2014-STG H2020 639088], EPSRC [1525292], CelluForce Inc., Canad