403 research outputs found
The associations between autistic traits and disordered eating/drive for muscularity are independent of anxiety and depression in females but not males
Previous research has shown a positive correlation between autistic traits and eating disorder symptoms, and this relationship appears to be independent of co-occurring mental health status. The current study followed a pre-registered analysis plan with the aim to investigate a previously unconsidered factor in the relationship between autistic traits and disorders of eating and body image: the drive for muscularity. Participants (N = 1068) completed the Autism Spectrum Quotient (AQ), Hospital Anxiety and Depression Scale (HADS), Eating Attitudes Test-26 (EAT-26) and Drive for Muscularity Scale (DMS). Positive correlations between AQ and EAT-26 and AQ and DMS were observed. In females, AQ remained significantly correlated with EAT-26 and DMS when controlling for co-occurring anxiety and depression symptoms, but this was not the case in males. These findings demonstrate the moderating role of sex, and the need to consider autistic traits in individuals diagnosed with, or at a heightened risk for, disorders of eating and body image
Iterated maps for clarinet-like systems
The dynamical equations of clarinet-like systems are known to be reducible to
a non-linear iterated map within reasonable approximations. This leads to time
oscillations that are represented by square signals, analogous to the Raman
regime for string instruments. In this article, we study in more detail the
properties of the corresponding non-linear iterations, with emphasis on the
geometrical constructions that can be used to classify the various solutions
(for instance with or without reed beating) as well as on the periodicity
windows that occur within the chaotic region. In particular, we find a regime
where period tripling occurs and examine the conditions for intermittency. We
also show that, while the direct observation of the iteration function does not
reveal much on the oscillation regime of the instrument, the graph of the high
order iterates directly gives visible information on the oscillation regime
(characterization of the number of period doubligs, chaotic behaviour, etc.)
Digital Simulation for Automobile Maneuvers
A new all-digital simulation of automobile handling allows severe maneuvers involving braking or accel eration and cornering. A novel feature is the in corporation of closed-loop control based on a mathematical model of the human driver. The program is modular and well-documented. The model includes provisions for nonlinear tire and suspension forces and moments; it also allows the user to switch off the nonlinearities and to include an antilock brake system.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68886/2/10.1177_003754978103700304.pd
Local Strain Heterogeneity Influences the Optoelectronic Properties of Halide Perovskites
Halide perovskites are promising semiconductors for optoelectronics, yet thin films show substantial microscale heterogeneity. Understanding the origins of these variations is essential for mitigating parasitic losses such as non-radiative decay. Here, we probe the structural and chemical origins of the heterogeneity by utilizing scanning X-ray diffraction beamlines at two different synchrotrons combined with high-resolution transmission electron microscopy to spatially characterize the crystallographic properties of individual micrometer-sized perovskite grains in high-quality films. We reveal new levels of heterogeneity on the ten-micrometer scale (super-grains) and even ten-nanometer scale (sub-grain domains). By directly correlating these properties with their corresponding local time-resolved photoluminescence properties, we find that regions showing the greatest luminescence losses correspond to strained regions, which arise from enhanced defect concentrations. Our work reveals remarkably complex heterogeneity across multiple length scales, shedding new light on the defect tolerance of perovskites
A large mid-Holocene estuary was not present in the lower River Murray, Australia
Recent research has suggested that during the mid-Holocene (c. 8500 to 5000 cal yr BP) a large estuary occupied the lower River Murray and its terminal lakes (Lakes Alexandrina and Albert: herein the Lower Lakes) in South Australia. This research has questioned both reconstructions of past River Murray discharge and contemporary environmental water provisions aimed at maintaining the freshwater state of the Lower Lakes. We show that (1) a large mid-Holocene estuary extending into the lower River Murray was not physically possible, and (2) that the River Murray and Lower Lakes were predominantly fresh during the mid-Holocene. Sea level was well below present at the time of purported initiation of estuarine sedimentation and, therefore, could not have allowed formation of an estuary. Holocene human occupation of the lower River Murray valley, that was reliant on freshwater resources, negates the existence of a large estuary in the valley. A variety of freshwater indicators in sediments from in, and around, the Lower Lakes negate the notion of significant marine incursion. Hence, current management of the Lower Lakes as freshwater ecosystems is consistent with their Holocene history.J. Tibby, B. Bourman, C. Wilson, L. M. Mosley, A. P. Belperio, D. D. Ryan ... et al
Occupational Communication as Boundary Mechanism
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69000/2/10.1177_073088847400100404.pd
Lattice QCD Simulations in External Background Fields
We discuss recent results and future prospects regarding the investigation,
by lattice simulations, of the non-perturbative properties of QCD and of its
phase diagram in presence of magnetic or chromomagnetic background fields.
After a brief introduction to the formulation of lattice QCD in presence of
external fields, we focus on studies regarding the effects of external fields
on chiral symmetry breaking, on its restoration at finite temperature and on
deconfinement. We conclude with a few comments regarding the effects of
electromagnetic background fields on gluodynamics.Comment: 31 pages, 10 figures, minor changes and references added. To appear
in Lect. Notes Phys. "Strongly interacting matter in magnetic fields"
(Springer), edited by D. Kharzeev, K. Landsteiner, A. Schmitt, H.-U. Ye
On the verge of Umdeutung in Minnesota: Van Vleck and the correspondence principle (Part One)
In October 1924, the Physical Review, a relatively minor journal at the time,
published a remarkable two-part paper by John H. Van Vleck, working in virtual
isolation at the University of Minnesota. Van Vleck combined advanced
techniques of classical mechanics with Bohr's correspondence principle and
Einstein's quantum theory of radiation to find quantum analogues of classical
expressions for the emission, absorption, and dispersion of radiation. For
modern readers Van Vleck's paper is much easier to follow than the famous paper
by Kramers and Heisenberg on dispersion theory, which covers similar terrain
and is widely credited to have led directly to Heisenberg's "Umdeutung" paper.
This makes Van Vleck's paper extremely valuable for the reconstruction of the
genesis of matrix mechanics. It also makes it tempting to ask why Van Vleck did
not take the next step and develop matrix mechanics himself.Comment: 82 page
SUFU haploinsufficiency causes a recognisable neurodevelopmental phenotype at the mild end of the Joubert syndrome spectrum.
Joubert syndrome (JS) is a recessively inherited ciliopathy characterised by congenital ocular motor apraxia (COMA), developmental delay (DD), intellectual disability, ataxia, multiorgan involvement, and a unique cerebellar and brainstem malformation. Over 40 JS-associated genes are known with a diagnostic yield of 60%-75%.In 2018, we reported homozygous hypomorphic missense variants of the SUFU gene in two families with mild JS. Recently, heterozygous truncating SUFU variants were identified in families with dominantly inherited COMA, occasionally associated with mild DD and subtle cerebellar anomalies.
We reanalysed next generation sequencing (NGS) data in two cohorts comprising 1097 probands referred for genetic testing of JS genes.
Heterozygous truncating and splice-site SUFU variants were detected in 22 patients from 17 families (1.5%) with strong male prevalence (86%), and in 8 asymptomatic parents. Patients presented with COMA, hypotonia, ataxia and mild DD, and only a third manifested intellectual disability of variable severity. Brain MRI showed consistent findings characterised by vermis hypoplasia, superior cerebellar dysplasia and subtle-to-mild abnormalities of the superior cerebellar peduncles. The same pattern was observed in two out of three tested asymptomatic parents.
Heterozygous truncating or splice-site SUFU variants cause a novel neurodevelopmental syndrome encompassing COMA and mild JS, which likely represent overlapping entities. Variants can arise de novo or be inherited from a healthy parent, representing the first cause of JS with dominant inheritance and reduced penetrance. Awareness of this condition will increase the diagnostic yield of JS genetic testing, and allow appropriate counselling about prognosis, medical monitoring and recurrence risk
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