The vertical distribution of ozone at Pretoria from July 1990 to June 1991 and its changes

Total ozone and the vertical distribution of ozone were measured at Pretoria between 1965 and 1968. Total ozone measurements recommenced in Pretoria in August 1989, and measurements of the vertical distribution of ozone near Pretoria recommenced in July 1990. Relative to the earlier data, mean monthly total ozone values are significantly higher in all months, with a mean annual relative increase of 12 percent. The recent profiles show a significant increase in the mean monthly concentration of ozone in the lowest 12 km. Concurrent to this increase a relative decrease in ozone concentration is shown between 12 and 42 km. The increased ozone concentration in the lower troposphere may be related to urbanization and the increase in ozone-forming nitrogen oxides over the last two decades. It is suggested that the decreased ozone concentration in the stratosphere and upper troposphere is evidence of the global decrease in the mid-latitudes of the Southern Hemisphere

A One-Dimensional Volcanic Plume Model for Predicting Ash Aggregation

During explosive volcanic eruptions, volcanic ash is ejected into the atmosphere, impacting aircraft safety and downwind communities. These volcanic clouds tend to be dominated by fine ash (μm in diameter), permitting transport over hundreds to thousands of kilometers. However, field observations show that much of this fine ash aggregates into clusters or pellets with faster settling velocities than individual particles. Models of ash transport and deposition require an understanding of aggregation processes, which depend on factors like moisture content and local particle collision rates. In this study, we develop a Plume Model for Aggregate Prediction, a one-dimensional (1D) volcanic plume model that predicts the plume rise height, concentration of water phases, and size distribution of resulting ash aggregates from a set of eruption source parameters. The plume model uses a control volume approach to solve mass, momentum, and energy equations along the direction of the plume axis. The aggregation equation is solved using a fixed pivot technique and incorporates a sticking efficiency model developed from analog laboratory experiments of particle aggregation within a novel turbulence tower. When applied to the 2009 eruption of Redoubt Volcano, Alaska, the 1D model predicts that the majority of the plume is over-saturated with water, leading to a high rate of aggregation. Although the mean grain size of the computed Redoubt aggregates is larger than the measured deposits, with a peak at 1 mm rather than 500 μm, the present results provide a quantitative estimate for the magnitude of aggregation in an eruption

Reviews

The following publications have been reviewed by the mentioned authors;Windsor Chairmaking by Thos Moser, reviewed by Bernard AylwardRelief Woodcarving by E. J. Tangerman, reviewed by Bernard AylwardWorking Green Wood with PEG by Patrick Spielman, reviewed by J. W. ThompsonWork Experience in Secondary Schools edited by John Eggleston, reviewed by Charles PeaceScale Model Cannon by Richard Stewart and Donald Heyes, reviewed by John EgglestonHow to Make Your Own Picture Frames by Hal Rogers and Ed Reinhardt, reviewed by John EgglestonThe Story of Craft by Edward Lucie Smith, reviewed by John EgglestonThe Landsdowne Book of Handcrafts reviewed by Roger BensonUnderstanding Design in the Home by Margaret Picton, reviewed by John EgglestonWoodturning Projects for Dining by John Sainsbury, reviewed by M. P. BourneCrafts Conference for Teachers - April 1982 published by Crafts Council, reviewed by Bernard L. MyersCraft Design Technology reviewed by M. JohnArt and Imaginations: A Study in the Philosophy of Mind by Roger Scruton, reviewed by G. H. Bantock'Forget all the rules you ever learned about Graphic Design including the ones in this Book by Bob Gill, reviewed by Cal SwannProfessional Smithing by Donald Streeter, reviewed by J. N. AtkinsGraphic Communication by John Twyford, reviewed by Cal Swan

Beta-decay of Mn-65 to Fe-65

The low energy structure of Fe-65 has been studied by means of gamma- and fast-timing spectroscopy. A level scheme of Fe-65 populated following the beta-decay of Mn-65 was established for the first time. It includes 41 levels and 85 transitions. The excitation energy of the beta-decaying isomer in Fe-65 has been precisely determined at 393.7(2) keV. The beta delayed neutron emission branch was measured as Pn = 7.9(12)%, which cannot be reconciled with the previously reported value of 21.0(5)%. Four gamma-rays and four excited states in Fe-64 were identified as being populated following the beta-n decay. Four lifetimes and five lifetime limits in the subnanosecond range have been measured using the Advanced Time-Delayed Method. The level scheme is compared with shell-model calculations. Tentative spin and parity assignments are proposed based on the observed transition rates, the calculations and the systematics of the region.Comment: Accepted in Physical Review

Development of an epigenetic age predictor for costal cartilage with a simultaneous somatic tissue differentiation system

Age prediction from DNA has been a topic of interest in recent years due to the promising results obtained when using epigenetic markers. Since DNA methylation gradually changes across the individual's lifetime, prediction models have been developed accordingly for age estimation. The tissue-dependence for this biomarker usually necessitates the development of tissue-specific age prediction models, in this way, multiple models for age inference have been constructed for the most commonly encountered forensic tissues (blood, oral mucosa, semen). The analysis of skeletal remains has also been attempted and prediction models for bone have now been reported. Recently, the VISAGE Enhanced Tool was developed for the simultaneous DNA methylation analysis of 8 age-correlated loci using targeted high-throughput sequencing. It has been shown that this method is compatible with epigenetic age estimation models for blood, buccal cells, and bone. Since when dealing with decomposed cadavers or postmortem samples, cartilage samples are also an important biological source, an age prediction model for cartilage has been generated in the present study based on methylation data collected using the VISAGE Enhanced Tool. In this way, we have developed a forensic cartilage age prediction model using a training set composed of 109 samples (19–74 age range) based on DNA methylation levels from three CpGs in FHL2, TRIM59 and KLF14, using multivariate quantile regression which provides a mean absolute error (MAE) of ± 4.41 years. An independent testing set composed of 72 samples (19–75 age range) was also analyzed and provided an MAE of ± 4.26 years. In addition, we demonstrate that the 8 VISAGE markers, comprising EDARADD, TRIM59, ELOVL2, MIR29B2CHG, PDE4C, ASPA, FHL2 and KLF14, can be used as tissue prediction markers which provide reliable blood, buccal cells, bone, and cartilage differentiation using a developed multinomial logistic regression model. A training set composed of 392 samples (n = 87 blood, n = 86 buccal cells, n = 110 bone and n = 109 cartilage) was used for building the model (correct classifications: 98.72%, sensitivity: 0.988, specificity: 0.996) and validation was performed using a testing set composed of 192 samples (n = 38 blood, n = 36 buccal cells, n = 46 bone and n = 72 cartilage) showing similar predictive success to the training set (correct classifications: 97.4%, sensitivity: 0.968, specificity: 0.991). By developing both a new cartilage age model and a tissue differentiation model, our study significantly expands the use of the VISAGE Enhanced Tool while increasing the amount of DNA methylation-based information obtained from a single sample and a single forensic laboratory analysis. Both models have been placed in the open-access Snipper forensic classification website.</p

Modelling UK house prices with structural breaks and conditional variance analysis

This paper differs from previous research by examining the existence of structural breaks in the UK regional house prices as well as in the prices of the different property types (flats, terraced, detached and semi-detached houses) in the UK as a whole, motivated by the uncertainty in the UK housing market and various financial events that may lead to structural changes within the housing market. Our paper enhances the conventional unit root tests by allowing for structural breaks, while including structural break tests strengthens our analysis. Our empirical results support the existence of structural breaks in the mean equation in seven out of thirteen regions of the UK as well as in three out of four property types, and in the variance equation in six regions and three property types. In addition, using a multivariate GARCH approach we examine both the behaviour of variances and covariances of the house price returns over time. Our results have significant implications for appropriate economic policy selection and investment management

Impact of motion compensation and partial volume correction for ¹⁸F-NaF PET/CT imaging of coronary plaque

Recent studies have suggested that ¹⁸F-NaF-PET enables visualization and quantification of plaque micro-calcification in the coronary tree. However, PET imaging of plaque calcification in the coronary arteries is challenging because of the respiratory and cardiac motion as well as partial volume effects. The objective of this work is to implement an image reconstruction framework, which incorporates compensation for respiratory as well as cardiac motion (MoCo) and partial volume correction (PVC), for cardiac ¹⁸F-NaF PET imaging in PET/CT. We evaluated the effect of MoCo and PVC on the quantification of vulnerable plaques in the coronary arteries. Realistic simulations (Biograph TPTV, Biograph mCT) and phantom acquisitions (Biograph mCT) were used for these evaluations. Different uptake values in the calcified plaques were evaluated in the simulations, while three "plaque-type" lesions of 36, 31 and 18 mm³ were included in the phantom experiments. After validation, the MoCo and PVC methods were applied in four pilot NaF-PET patient studies. In all cases, the MoCo-based image reconstruction was performed using the STIR software. The PVC was obtained from a local projection (LP) method, previously evaluated in preclinical and clinical PET. The results obtained show a significant increase of the measured lesion-to-background ratios (LBR) in the MoCo+PVC images. These ratios were further enhanced when using directly the tissue-activities from the LP method, making this approach more suitable for the quantitative evaluation of coronary plaques. When using the LP method on the MoCo images, LBR increased between 200% and 1119% in the simulated data, between 212% and 614% in the phantom experiments and between 46% and 373% in the plaques with positive uptake observed in the pilot patients. In conclusion, we have built and validated a STIR framework incorporating MoCo and PVC for ¹⁸NaF PET imaging of coronary plaques. First results indicate an improved quantification of plaque-type lesions