Availability Estimation for Facilities in Extreme Geographical Locations

A value added analysis for the Reliability. Availability and Maintainability of McMurdo Ground Station was developed, which will be a useful tool for system managers in sparing, maintenance planning and determining vital performance metrics needed for readiness assessment of the upgrades to the McMurdo System. Output of this study can also be used as inputs and recommendations for the application of Reliability Centered Maintenance (RCM) for the system. ReliaSoft's BlockSim. a commercial Reliability Analysis software package, has been used to model the availability of the system upgrade to the National Aeronautics and Space Administration (NASA) Near Earth Network (NEN) Ground Station at McMurdo Station in the Antarctica. The logistics challenges due to the closure of access to McMurdo Station during the Antarctic winter was modeled using a weighted composite of four Weibull distributions. one of the possible choices for statistical distributions throughout the software program and usually used to account for failure rates of components supplied by different manufacturers. The inaccessibility of the antenna site on a hill outside McMurdo Station throughout one year due to severe weather was modeled with a Weibull distribution for the repair crew availability. The Weibull distribution is based on an analysis of the available weather data for the antenna site for 2007 in combination with the rules for travel restrictions due to severe weather imposed by the administrating agency, the National Science Foundation (NSF). The simulations resulted in an upper bound for the system availability and allowed for identification of components that would improve availability based on a higher on-site spare count than initially planned

Audit of pediatric ENT injuries

Background: Ear, Nose and throat (ENT) injuries are relatively common in children. Sometimes they may result in disfigurement or dysfunction of the affected parts. This study was aimed at the pattern and mechanisms of ENT injuries encountered by children in Ilorin located in north central Nigeria. It is therefore our hope that the information will go a long way to assist other African countries as well in health care plans for children. Objectives: The study was aimed at determining the pattern and causes of ENT injuries in children in Ilorin. Methodology: This was a descriptive cross sectional, prospective study of all pediatrics patients aged 15 years and below who were managed between January 2005 and December 2009 (a period of 5 years) for ENT trauma in the accident & emergency unit, wards and clinics of University of Ilorin Teaching Hospital. Most of them were treated as out-patients; a few of them needed admission for some procedures. Patients with injuries to other areas than ENT were not included in this study. The data that were analyzed included the age, sex, presenting complaints, duration of symptoms prior to presentation, diagnoses, treatments and complications. Results: Two hundred and seventy-one children were studied, of which 168 (62.0%) were males and 103 (38.0%) were females. Most of the children, 97 (35.8%), were between age group of 6-10 years, 81 (29.9%) aged 5 years and below, while the rest were 11-15 years of age. Injuries due to foreign bodies in Ear, Nose and Throat accounted for 80 (29.5%) of the causes. Falls accounted for 60 (24.4%) of cases while Road Traffic Injuries (RTI), 42 (15.5%) of cases. Bleeding was the commonest presenting symptom. Most of the children, 97 (35.8%) presented within 1 hour of injury while the least, 45 (16.6%), presented more than 8 hours after the injury. 132 (48.7%) had injuries in the Ear, 117 (43.2%) in the Nose and 22 (8.1%) in the Throat. Conclusion: ENT injuries in pediatrics are relatively common in our environment with injuries from FB insertion/ingestion being the commonest. This is closely followed by falls. Several disabilities and morbidity may result from the trauma like anosmia, facial palsy and permanently depressed nose. These have impact on psychology of the child. For these reason close monitoring of children by parents and care-givers cannot be overemphasized. Also these injuries are avoidable causes of death and disability in children. (Int J Biomed Sci 2011; 7 (3): 218-221

Differences and Commonalities in Physical, Chemical and Mineralogical Properties of Zanzibari Geophagic Soils

The function of human geophagy has long been questioned. We sought to test hypotheses concerning its potential physiological effects through analysis of soils and patterns in geophagy behavior. Eleven samples of geophagic soils consumed by pregnant women on Pemba Island, Zanzibar, Tanzania, were characterized according to their color, texture, major element chemistry, trace element chemistry, bulk mineralogy, and clay mineralogy. An epidemiological study (N = 2367) and ethnographic interviews (N = 57) on Pemba yielded information about geophagic behaviors and socio-demographic and biological characteristics of those who consumed earth. The soils varied widely in color, ranging from light red to white through various shades of brown and yellow, and texture ranged from clay to sand. Major element chemistry of the soils also varied greatly; most were low in Fe and Ca. Trace elements, whether of biological or non-biological significance, were uniformly low when compared with normal ranges of mineral soils. The sole commonality among the samples is that all clay fractions were dominated by a kaolin mineral: kaolinite, halloysite, or a mixture of both. Geophagy behavior also varied greatly, with one major exception: a greater proportion of pregnant women (7.1%) and young children (4.5%) consumed earth than non-pregnant women (0.2%) or men (0%). The presence of kaolin mineral in all samples, its palliative and detoxifying properties, and the highest prevalence of geophagy among those most biologically vulnerable suggest that geophagy may be a protective behavior

Determination of neo- and d-chiro-Inositol Hexakisphosphate in Soils by Solution 31P NMR Spectroscopy

The inositol phosphates are an abundant but poorly understood group of organic phosphorus compounds found widely in the environment. Four stereoisomers of inositol hexakisphosphate (IP6) occur, although for three of these (scyllo, flea, and D-chiro) the origins, dynamics, and biological function remain unknown, due in large part to analytical limitations in their measurement in environmental samples. We synthesized authentic neo- and n-chiro-IP6 and used them to identify signals from these compounds in three soils from the Falkland Islands. Both compounds resisted hypobromite oxidation and gave quantifiable P-31 NMR signals at delta = 6.67 ppm (equatorial phosphate groups of the 4-equatorial/2-axial conformer of neo-IP6) and delta = 6.48 ppm (equatorial phosphate groups of the 2-equatorial/4-axial conformer of D-chiro-IP6) in soil extracts. Inositol hexakisphosphate accounted for 46-54% of the soil organic phosphorus, of which the four stereoisomers constituted, on average, 55.9% (myo), 32.8% (scyllo), 6.1% (neo), and 5.2% (n-chiro). Reappraisal of the literature based on the new signal assignments revealed that neo- and D-chiro-IP6 occur widely in both terrestrial and aquatic ecosystems. These results confirm that the inositol phosphates can constitute a considerable fraction of the organic phosphorus in soils and reveal the prevalence of neo- and D-chiro-IP6 in the environment. The hypobromite oxidation and solution P-31 NMR spectroscopy procedure allows the simultaneous quantification of all four IP6 stereoisomers in environmental samples and provides a platform for research into the origins and ecological significance of these enigmatic compounds

May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension

Aims Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide and fewer than half of those with hypertension are aware of it. May Measurement Month (MMM) is a global campaign set up in 2017, to raise awareness of high BP and as a pragmatic solution to a lack of formal screening worldwide. The 2018 campaign was expanded, aiming to include more participants and countries. Methods and results Eighty-nine countries participated in MMM 2018. Volunteers (≥18 years) were recruited through opportunistic sampling at a variety of screening sites. Each participant had three BP measurements and completed a questionnaire on demographic, lifestyle, and environmental factors. Hypertension was defined as a systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg, or taking antihypertensive medication. In total, 74.9% of screenees provided three BP readings. Multiple imputation using chained equations was used to impute missing readings. 1 504 963 individuals (mean age 45.3 years; 52.4% female) were screened. After multiple imputation, 502 079 (33.4%) individuals had hypertension, of whom 59.5% were aware of their diagnosis and 55.3% were taking antihypertensive medication. Of those on medication, 60.0% were controlled and of all hypertensives, 33.2% were controlled. We detected 224 285 individuals with untreated hypertension and 111 214 individuals with inadequately treated (systolic BP ≥ 140 mmHg or diastolic BP ≥ 90 mmHg) hypertension. Conclusion May Measurement Month expanded significantly compared with 2017, including more participants in more countries. The campaign identified over 335 000 adults with untreated or inadequately treated hypertension. In the absence of systematic screening programmes, MMM was effective at raising awareness at least among these individuals at risk

Population structure and evolutionary history of the greater cane rat (Thryonomys swinderianus) from the Guinean Forests of West Africa

Grasscutter (Thryonomys swinderianus) is a large-body old world rodent found in sub-Saharan Africa. The body size and the unique taste of the meat of this major crop pest have made it a target of intense hunting and a potential consideration as a micro-livestock. However, there is insufficient knowledge on the genetic diversity of its populations across African Guinean forests. Herein, we investigated the genetic diversity, population structures and evolutionary history of seven Nigerian wild grasscutter populations together with individuals from Cameroon, Republic of Benin, and Ghana, using five mitochondrial fragments, including D-loop and cytochrome b (CYTB). D-loop haplotype diversity ranged from 0.571 (± 0.149) in Republic of Benin to 0.921 (± 0.013) in Ghana. Within Nigeria, the haplotype diversity ranged from 0.659 (± 0.059) in Cross River to 0.837 (± 0.075) in Ondo subpopulation. The fixation index (FST), haplotype frequency distribution and analysis of molecular variance revealed varying levels of population structures across populations. No significant signature of population contraction was detected in the grasscutter populations. Evolutionary analyses of CYTB suggests that South African population might have diverged from other populations about 6.1 (2.6–10.18, 95% CI) MYA. Taken together, this study reveals the population status and evolutionary history of grasscutter populations in the region

Full Length Research Article - Prevalence of Hypertension in a University Community in South West Nigeria

A worksite study of hypertension prevalence was carried out in a university community in Southwestern Nigeria. Overall crude prevalence was 21% in the respondent population. About 16% of these were already on treatment with medicines. The study established no significant (p>0.05) relationship between coffee consumption and hypertension. Prevalence was 32% in subjects with over 3 children, while among subjects with eye problem, diabetics and those who took local kola nuts and it was 18.6%, 1.9% and 7.4%, respectively. There is need for increased awareness of the disease and other cardiovascular risk factors within the populace and to encourage the possession or provision of self-measurement blood pressure devices

Availability Estimation for Facilities in Extreme Geographical Locations

Presentation to support a Summit/TIM with various Stakeholders (Ground and Flight) to perform a GAP analysis associated with ground and spacecraft maintenance, maintainability, and availability activities in order to identify missing Agency planning and guidance materials