Effect of image tilt of a virtual image display on simulated transport touchdown performance

An evaluation of the visual effect of image tilt of a refractive lens display system is presented. The system was used to present a rudimentary computer generated out the window scene to the pilot of a flight simulator during approach, flare, and touchdown. Comparisons are made of sink rate at touchdown and performances for untilted and tilted displays. Sixty four landings with each condition for a total of 128 touchdowns were made by 3 subjects. Performance measures, such as the flare and touchdown footprints, were recorded and analyzed. The visual effect of the image tilt was investigated for a terrain model board scene

Garnet–monazite rare earth element relationships in sub-solidus metapelites: a case study from Bhutan

A key aim of modern metamorphic geochronology is to constrain precise and accurate rates and timescales of tectonic processes. One promising approach in amphibolite and granulite-facies rocks links the geochronological information recorded in zoned accessory phases such as monazite to the pressure–temperature information recorded in zoned major rock-forming minerals such as garnet. Both phases incorporate rare earth elements (REE) as they crystallize and their equilibrium partitioning behaviour potentially provides a useful way of linking time to temperature. We report REE data from sub-solidus amphibolite-facies metapelites from Bhutan, where overlapping ages, inclusion relationships and Gd/Lu ratios suggest that garnet and monazite co-crystallized. The garnet–monazite REE relationships in these samples show a steeper pattern across the heavy (H)REE than previously reported. The difference between our dataset and the previously reported data may be due to a temperature-dependence on the partition coefficients, disequilibrium in either dataset, differences in monazite chemistry or the presence or absence of a third phase that competed for the available REE during growth. We urge caution against using empirically-derived partition coefficients from natural samples as evidence for, or against, equilibrium of REE-bearing phases until monazite–garnet partitioning behaviour is better constrained

InSb charge coupled infrared imaging device: The 20 element linear imager

The design and fabrication of the 8585 InSb charge coupled infrared imaging device (CCIRID) chip are reported. The InSb material characteristics are described along with mask and process modifications. Test results for the 2- and 20-element CCIRID's are discussed, including gate oxide characteristics, charge transfer efficiency, optical mode of operation, and development of the surface potential diagram

Distribution of O-Acetylated Sialic Acids among Target Host Tissues for Influenza Virus.

Sialic acids (Sias) are important glycans displayed on the cells and tissues of many different animals and are frequent targets for binding and modification by pathogens, including influenza viruses. Influenza virus hemagglutinins bind Sias during the infection of their normal hosts, while the encoded neuraminidases and/or esterases remove or modify the Sia to allow virion release or to prevent rebinding. Sias naturally occur in a variety of modified forms, and modified Sias can alter influenza virus host tropisms through their altered interactions with the viral glycoproteins. However, the distribution of modified Sia forms and their effects on pathogen-host interactions are still poorly understood. Here we used probes developed from viral Sia-binding proteins to detect O-acetylated (4-O-acetyl, 9-O-acetyl, and 7,9-O-acetyl) Sias displayed on the tissues of some natural or experimental hosts for influenza viruses. These modified Sias showed highly variable displays between the hosts and tissues examined. The 9-O-acetyl (and 7,9-) modified Sia forms were found on cells and tissues of many hosts, including mice, humans, ferrets, guinea pigs, pigs, horses, dogs, as well as in those of ducks and embryonated chicken egg tissues and membranes, although in variable amounts. The 4-O-acetyl Sias were found in the respiratory tissues of fewer animals, being primarily displayed in the horse and guinea pig, but were not detected in humans or pigs. The results suggest that these Sia variants may influence virus tropisms by altering and selecting their cell interactions. IMPORTANCE Sialic acids (Sias) are key glycans that control or modulate many normal cell and tissue functions while also interacting with a variety of pathogens, including many different viruses. Sias are naturally displayed in a variety of different forms, with modifications at several positions that can alter their functional interactions with pathogens. In addition, Sias are often modified or removed by enzymes such as host or pathogen esterases or sialidases (neuraminidases), and Sia modifications can alter those enzymatic activities to impact pathogen infections. Sia chemical diversity in different hosts and tissues likely alters the pathogen-host interactions and influences the outcome of infection. Here we explored the display of 4-O-acetyl, 9-O-acetyl, and 7,9-O-acetyl modified Sia forms in some target tissues for influenza virus infection in mice, humans, birds, guinea pigs, ferrets, swine, horses, and dogs, which encompass many natural and laboratory hosts of those viruses

Prediction and prevention of the next pandemic zoonosis.

Most pandemics--eg, HIV/AIDS, severe acute respiratory syndrome, pandemic influenza--originate in animals, are caused by viruses, and are driven to emerge by ecological, behavioural, or socioeconomic changes. Despite their substantial effects on global public health and growing understanding of the process by which they emerge, no pandemic has been predicted before infecting human beings. We review what is known about the pathogens that emerge, the hosts that they originate in, and the factors that drive their emergence. We discuss challenges to their control and new efforts to predict pandemics, target surveillance to the most crucial interfaces, and identify prevention strategies. New mathematical modelling, diagnostic, communications, and informatics technologies can identify and report hitherto unknown microbes in other species, and thus new risk assessment approaches are needed to identify microbes most likely to cause human disease. We lay out a series of research and surveillance opportunities and goals that could help to overcome these challenges and move the global pandemic strategy from response to pre-emption

Design of Multistep Aging Treatments of 2099 (C458) Al-Li Alloy

Multistep artificial aging treatments coupled with various natural aging times for aluminum lithium 2099 alloy (previously called C458) are discussed to obtain mechanical tensile properties in the T6 condition that match those in the T861 condition, having a yield strength in the range of 414-490 MPa (60-71 ksi), an ultimate strength in the range of 496-538 MPa (72-78 ksi), and 10-13% elongation. Yield and ultimate tensile strengths from 90-100% of the strength of the as-received material (in the T861 condition) were obtained. The highest tensile strengths were consistently obtained with two-step, low-to-high temperature artificial aging treatments consisting of a first step at 120 degrees C (248 degrees F) for 12-24 h followed by a second step between 165 and 180 degrees C (329-356 degrees F) for 48-100 h. These T6-type heat treatments produced average yield and ultimate strengths in the longitudinal direction in the range of 428-472 MPa (62.1-68.5 ksi) and 487-523 MPa (70.6-75.9 ksi), respectively, as well as lower yield strength anisotropy when compared with the as-received material in the T861 condition

A two-circle powder diffractometer for synchrotron radiation on Station 2.3 at the SRS

The two-circle powder diffractometer on Station 8.3 at the SRS has recently been relocated to station 2.3, some half the distance from a dipole radiation source with the same nominal 1.2T field. The purpose of this paper is to detail the changes and modifications to the diffractometer operation

X-Ray surface brightness and gas density fluctuations in the Coma cluster

X-ray surface brightness fluctuations in the core ($650 \times 650$ kpc) region of the Coma cluster observed with XMM-Newton and Chandra are analyzed using a 2D power spectrum approach. The resulting 2D spectra are converted to 3D power spectra of gas density fluctuations. Our independent analyses of the XMM-Newton and Chandra observations are in excellent agreement and provide the most sensitive measurements of surface brightness and density fluctuations for a hot cluster. We find that the characteristic amplitude of the volume filling density fluctuations relative to the smooth underlying density distribution varies from 7-10% on scales of $\sim$500 kpc down to $\sim$5% at scales $\sim$ 30 kpc. On smaller spatial scales, projection effects smear the density fluctuations by a large factor, precluding strong limits on the fluctuations in 3D. On the largest scales probed (hundreds of kpc), the dominant contributions to the observed fluctuations most likely arise from perturbations of the gravitational potential by the two most massive galaxies in Coma, NGC4874 and NGC4889, and the low entropy gas brought to the cluster by an infalling group. Other plausible sources of X-ray surface brightness fluctuations are discussed, including turbulence, metal abundance variations, and unresolved sources. Despite a variety of possible origins for density fluctuations, the gas in the Coma cluster core is remarkably homogeneous on scales from $\sim$ 500 to $\sim$30 kpc.Comment: published in MNRA