Visualization of amphetamine and its analogues in TLC

Derivatisation followed by iodine azide reaction was employed for detection of amphetamines and its analogues in TLC. The derivatisation reaction with phenyl isothiocyanate took place directly on the TLC plate before the developing step. Afterwards, the plate was sprayed with a mixture of sodium azide and starch solution and then exposed to iodine vapour. The obtained limits of detection were compared with other commonly visualization techniques: UV, iodine vapour, Marquis and Simon’s reagents, ninhydrin, Fast Black K

Through the cyber metamorphosis. The antique tradition in the cyberspace

There are a lot of the dynamic meanings - important messages for the west civilization - in the antique tradition, deeply rooted in every medium. The authors of this text are showing us a lot of problems, connected with the ontological statue of text, context and relations among (not only between) sender and receiver, during the creating antique meanings in the different kinds of the communication. To be able to describe contemporary metamorphosis of the antique tradition they (the authors) are presenting us the most important changes in the west cultural reading - „through" the Internet - the antique heritage.There are a lot of the dynamic meanings - important messages for the west civilization - in the antique tradition, deeply rooted in every medium. The authors of this text are showing us a lot of problems, connected with the ontological statue of text, context and relations among (not only between) sender and receiver, during the creating antique meanings in the different kinds of the communication. To be able to describe contemporary metamorphosis of the antique tradition they (the authors) are presenting us the most important changes in the west cultural reading - „through" the Internet - the antique heritage

Direction-sensitive graphene flow sensor

Graphene flow sensors hold great prospects for applications, but also encounter many difficulties, such as unwanted electrochemical phenomena, low measurable signal and limited dependence on the flow direction. This study proposes a novel approach allowing for the detection of a flow direction-dependent electric signal in aqueous solutions of salts, acids and bases. The key element in the proposed solution is the use of a reference electrode which allows external gating of the graphene structure. Using external gating enables to enhance substantially the amplitude of the flow-generated signal. Simultaneous measurement of the reference electrode current allows us to recover a flow-direction-sensitive component of the flow-induced voltage in graphene. The obtained results are discussed in terms of the Coulomb interaction and other phenomena which can be present at the interface of graphene with the aqueous solution.Comment: 7 pages, 6 figure

Korzyści z podejmowania regularnej aktywności fizycznej przez osoby starsze = The benefits of regular physical activity for the elderly

Kaźmierczak U., Radzimińska A., Dzierżanowski M., Bułatowicz I., Strojek K., Srokowski G., Zukow W. Korzyści z podejmowania regularnej aktywności fizycznej przez osoby starsze = The benefits of regular physical activity for the elderly. Journal of Education, Health and Sport. 2015;5(1):56-68. ISSN 2391-8306. DOI: 10.5281/zenodo.13935http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%281%29%3A56-68https://pbn.nauka.gov.pl/works/524287http://dx.doi.org/10.5281/zenodo.13935Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive Deklaracja.Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie.Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).© The Author (s) 2015;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 15.06.2014. Revised 05.10.2014. Accepted: 25.12.2014. Korzyści z podejmowania regularnej aktywności fizycznej przez osoby starszeThe benefits of regular physical activity for the elderly Kaźmierczak U.¹, Radzimińska A.¹, Dzierżanowski M.², Bułatowicz I.¹, Strojek K.¹, Srokowski G.¹, Zukow W.³ Katedra Fizjoterapii CM UMK w Toruniu1Zakład Kinezyterapii i Masażu Leczniczego UMK CM w Toruniu²Zakład Terapii Manualnej UMK CM w Toruniu3Wydział Kultury Fizycznej, Zdrowia i Turystyki, Uniwersytet Kazimierza Wielkiego w Bydgoszczy Słowa kluczowe: regularna aktywność fizyczna, osoby starsze. Keywords: regular physical activity, elderly. AbstraktW państwach rozwiniętych i rozwijających się coraz większą grupę społeczeństw stanowią seniorzy.Świadomość problemu spowodowała podjęcie powszechnej dyskusji ekspertów i praktyków z dziedzin medycznych na temat konieczności działań niezbędnych dla zapewnienia społeczeństwom pomyślnej starości.Od dawna wskazuje się, że brak aktywności ruchowej jest dla zdrowia niebezpieczny.Starzeniu się układu sercowo-naczyniowego towarzyszy dużo niekorzystnych zmian strukturalnych, czynnościowych i biochemicznych. Za typowe dla tego okresu zmiany uważa się osłabienie możliwości relaksacji włókien mięśniowych, co może być przyczyną rozkurczowej niewydolności serca.Trening zdrowotny – jest rodzajem aktywności fizycznej wykonywanej z powodów medycznych. Celem jest uzyskanie efektów fizycznych oraz psychicznych przeciwdziałających zmniejszaniu się zdolności adaptacyjnych organizmu.Eksperci przekonują osoby starsze o korzyściach płynących z aktywnego fizycznie stylu życia. Bogate piśmiennictwo poruszające tematykę medycznych aspektów procesu starzenia, mówi o niezaprzeczalnym znaczeniu ruchu dla toczących się w ludzkim ciele procesów inwolucyjnych. Aktywność fizyczna odpowiednio dozowana jest w stanie wyraźnie zmniejszyć negatywny wpływ tych zmian i jak najdłużej pozwolić utrzymać zdrowie fizyczne, psychiczne i społeczne. Zauważono, że systematycznie dozowany wysiłek fizyczny zmniejsza ryzyko wystąpienia wielu chorób np. cukrzycy, miażdżycy, choroby niedokrwiennej serca.Liczne badania naukowe i bogate piśmiennictwo gerontologiczne przedstawiają najnowsze doniesienia specjalistów o tym, jak należy prawidłowo przygotować i prowadzić trening fizyczny z osobami starszymi. Ludzki organizm zaczyna starzeć się około 20-25 roku życia. Zmiany dotyczą wszystkich układów ciała. Najbardziej odczuwalne w życiu codziennym są te, które zachodzą w układzie krążeniowo-oddechowym i mięśniowo-szkieletowym. Trening fizyczny dla osoby starszej, aby był skuteczny i bezpieczny, powinien być skonstruowany i nadzorowany przez specjalistę. AbstractIn developed and developing countries an increasing group of societies are seniors. Awareness of the problem has led to widespread discussion of experts and practitioners from the fields of medical devices on the need for the measures necessary to ensure that societies successful old age. For a long time, indicates that the lack of motor activity is dangerous to health. Aging of the cardiovascular system is accompanied by a lot of adverse structural changes and biochemical function.For typical of this period of change is believed to be weakening the possibility of relaxation of the muscle fibers, which may cause diastolic heart failure. Training of health-is a type of physical activity performed for medical reasons. The goal is to get mental and physical effects against reducing the adaptability of the body. Experts are finding older people about the benefits of a physically active lifestyle. Rich writing evocative theme of medical aspects of the aging process, speaks of undeniable importance for traffic in human flesh involutional processes. Physical activity appropriately dosed is able to clearly reduce the negative impact of these changes and as long as you can afford to maintain the physical, mental and social health. It was noted that systematically dosed exercise reduces the risk of many diseases, eg. diabetes mellitus, atherosclerosis, coronary heart disease.Numerous scientific studies and extensive external links gerontologiczne submit the latest reports of professionals about how to properly prepare and conduct physical training with the elderly. The human body begins to age about 20-25 years of age. The changes apply to all body systems. Most felt in everyday life are the ones that occur in the breathing cardiopulmonary and musculo-skeletal. Physical training for older persons, in order to be effective and safe, should be designed and supervised by a specialist

Nauki o polityce publicznej

Uniwersytet Warszawsk

The Principle Of Local Rotational Invariance And The Coexistence Of Magnetism, Charge And Superconductivity

We propose a macroscopic description of the superconducting state in presence of an applied external magnetic field in terms of first order differential equations. They describe a corrugated two-component order parameter intertwined with a spin-charged background, caused by spin correlations and charged dislocations. The first order differential equations are a consequence of a Weitzenb\"ock-Liechnorowitz identity which renders a SUL(2) \otimes UL(1) invariant ground state, based on (L) local rotational and electromagnetic gauge symmetry. The proposal is based on a long ago developed formalism by \'Elie Cartan to investigate curved spaces, viewed as a collection of small Euclidean granules that are translated and rotated with respect to each other. \'Elie Cartan's formalism unveils the principle of local rotational invariance as a gauge symmetry because the global SU(2) invariance of the order parameter is turned local by the interlacement of spin and charge to pairing.Comment: 19 pages, 3 figure

Detection of hydrogen fluoride absorption in diffuse molecular clouds with Herschel/HIFI: a ubiquitous tracer of molecular gas

We discuss the detection of absorption by interstellar hydrogen fluoride (HF) along the sight line to the submillimeter continuum sources W49N and W51. We have used Herschel's HIFI instrument in dual beam switch mode to observe the 1232.4762 GHz J = 1 - 0 HF transition in the upper sideband of the band 5a receiver. We detected foreground absorption by HF toward both sources over a wide range of velocities. Optically thin absorption components were detected on both sight lines, allowing us to measure - as opposed to obtain a lower limit on - the column density of HF for the first time. As in previous observations of HF toward the source G10.6-0.4, the derived HF column density is typically comparable to that of water vapor, even though the elemental abundance of oxygen is greater than that of fluorine by four orders of magnitude. We used the rather uncertain N(CH)-N(H2) relationship derived previously toward diffuse molecular clouds to infer the molecular hydrogen column density in the clouds exhibiting HF absorption. Within the uncertainties, we find that the abundance of HF with respect to H2 is consistent with the theoretical prediction that HF is the main reservoir of gas-phase fluorine for these clouds. Thus, hydrogen fluoride has the potential to become an excellent tracer of molecular hydrogen, and provides a sensitive probe of clouds of small H2 column density. Indeed, the observations of hydrogen fluoride reported here reveal the presence of a low column density diffuse molecular cloud along the W51 sight line, at an LSR velocity of ~ 24kms-1, that had not been identified in molecular absorption line studies prior to the launch of Herschel.Comment: 4 pages, 3 figures, A&A Letter special issue, accepted on 07/13/201

Cell cycle-dependent phosphorylation of pRb-like protein in root meristem cells of Vicia faba

The retinoblastoma tumor suppressor protein (pRb) regulates cell cycle progression by controlling the G1-to-S phase transition. As evidenced in mammals, pRb has three functionally distinct binding domains and interacts with a number of proteins including the E2F family of transcription factors, proteins with a conserved LxCxE motif (D-type cyclin), and c-Abl tyrosine kinase. CDK-mediated phosphorylation of pRb inhibits its ability to bind target proteins, thus enabling further progression of the cell cycle. As yet, the roles of pRb and pRb-binding factors have not been well characterized in plants. By using antibody which specifically recognizes phosphorylated serines (S807/811) in the c-Abl tyrosine kinase binding C-domain of human pRb, we provide evidence for the cell cycle-dependent changes in pRb-like proteins in root meristems cells of Vicia faba. An increased phosphorylation of this protein has been found correlated with the G1-to-S phase transition

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