7,190 research outputs found
Atmospheric temperature profiles using satellite-borne laser
Satellite-borne carbon dioxide laser system for obtaining vertical temperature profiles of atmospher
The polar temperature of Venus
Interferometric and polarization measurements of polar regions of Venu
FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel
Hair cells in mouse cochlear cultures are selectively labeled by brief exposure to FM1-43, a styryl dye used to study endocytosis and exocytosis. Real-time confocal microscopy indicates that dye entry is rapid and via the apical surface. Cooling to 4°C and high extracellular calcium both reduce dye loading. Pretreatment with EGTA, a condition that breaks tip links and prevents mechanotransducer channel gating, abolishes subsequent dye loading in the presence of calcium. Dye loading recovers after calcium chelation with a time course similar to that described for tip-link regeneration. Myo7a mutant hair cells, which can transduce but have all mechanotransducer channels normally closed at rest, do not label with FM1-43
unless the bundles are stimulated by large excitatory stimuli.
Extracellular perfusion of FM1-43 reversibly blocks mechanotransduction with half-blocking concentrations in the low micromolar range. The block is reduced by high extracellular calcium and is voltage dependent, decreasing at extreme positive and negative potentials, indicating that FM1-43 behaves as a permeant blocker of the mechanotransducer channel. The time course for the relief of block after voltage steps to extreme potentials further suggests that FM1-43 competes with other cations for binding sites within the pore of the channel. FM1-43 does not block the transducer channel from the intracellular side at concentrations that would cause complete block when applied extracellularly. Calcium chelation and FM1-43 both reduce the ototoxic effects of the aminoglycoside antibiotic neomycin sulfate, suggesting that FM1-43 and aminoglycosides
enter hair cells via the same pathway
Elliptic flow of thermal dileptons in relativistic nuclear collisions
We calculate the transverse momentum and invariant mass dependence of
elliptic flow of thermal dileptons for Au+Au collisions at the Relativistic
Heavy Ion Collider. The system is described using hydrodynamics, with the
assumption of formation of a thermalized quark-gluon plasma at some early time,
followed by cooling through expansion, hadronization and decoupling. Dileptons
are emitted throughout the expansion history: by annihilation of quarks and
anti-quarks inthe early quark-gluon plasma stage and through a set of hadronic
reactions during the late hadronic stage. The resulting differential elliptic
flow exhibits a rich structure, with different dilepton mass windows providing
access to different stages of the expansion history. Elliptic flow measurements
for dileptons,combined with those of hadrons and direct photons, are a powerful
tool for mapping the time-evolution of heavy-ion collisions.Comment: Latex 8 pages including a total of 13 postscript figures. Added 2
figures, additional references, and expanded discussions. Figures modified
for better viewing. To appear in Phys. Rev.
The Right of the Older Worker to Accrue Pension Benefits: Problems of Federal Law Exceptions and State Law Preemption
Gender classification of face images: the role of global and feature-based information
Peer reviewe
meson broadening and dilepton production in heavy ion collisions
The modification of the width of the rho meson due to in-medium decays and
collisions is evaluated. In high temperature and/or high density hadronic
matter, the collision width is much larger than the one-loop decay width. The
large width of the meson in matter seems to be consistent with some
current interpretations of the mass spectra measured at the CERN/SPS.Comment: 4 pages, LaTeX, including 4 Postscript figures, to appear in Proc. of
QM'99, Nucl. Phys.
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