5,139 research outputs found
Spatially resolved ultrafast precessional magnetization reversal
Spatially resolved measurements of quasi-ballistic precessional magnetic
switching in a microstructure are presented. Crossing current wires allow
detailed study of the precessional switching induced by coincident longitudinal
and transverse magnetic field pulses. Though the response is initially
spatially uniform, dephasing occurs leading to nonuniformity and transient
demagnetization. This nonuniformity comes in spite of a novel method for
suppression of end domains in remanence. The results have implications for the
reliability of ballistic precessional switching in magnetic devices.Comment: 17 pages (including 4 figures), submitted to Phys. Rev. Let
Nuclear like effects in proton-proton collisions at high energy
We show that several effects considered nuclear effects are not nuclear in
the sense that they do not only occur in nucleus-nucleus and hadron-nucleus
collisions but, as well, they are present in hadron-hadron (proton-proton)
collisions. The matter creation mechanism in hh, hA and AA collisions is always
the same. The pT suppression of particles produced in large multiplicity events
compared to low multiplicity events, the elliptic flow and the Cronin effect
are predicted to occur in pp collisions at LHC energies as a consequence of the
obtained high density partonic medium
Dwarfism with joint laxity in Friesian horses is associated with a splice site mutation in B4GALT7
Background: Inbreeding and population bottlenecks in the ancestry of Friesian horses has led to health issues such as dwarfism. The limbs of dwarfs are short and the ribs are protruding inwards at the costochondral junction, while the head and back appear normal. A striking feature of the condition is the flexor tendon laxity that leads to hyperextension of the fetlock joints. The growth plates of dwarfs display disorganized and thickened chondrocyte columns. The aim of this study was to identify the gene defect that causes the recessively inherited trait in Friesian horses to understand the disease process at the molecular level.
Results: We have localized the genetic cause of the dwarfism phenotype by a genome wide approach to a 3 Mb region on the p-arm of equine chromosome 14. The DNA of two dwarfs and one control Friesian horse was sequenced completely and we identified the missense mutation ECA14:g.4535550C> T that cosegregated with the phenotype in all Friesians analyzed. The mutation leads to the amino acid substitution p.(Arg17Lys) of xylosylprotein beta 1,4-galactosyltransferase 7 encoded by B4GALT7. The protein is one of the enzymes that synthesize the tetrasaccharide linker between protein and glycosaminoglycan moieties of proteoglycans of the extracellular matrix. The mutation not only affects a conserved arginine codon but also the last nucleotide of the first exon of the gene and we show that it impedes splicing of the primary transcript in cultured fibroblasts from a heterozygous horse. As a result, the level of B4GALT7 mRNA in fibroblasts from a dwarf is only 2 % compared to normal levels. Mutations in B4GALT7 in humans are associated with Ehlers-Danlos syndrome progeroid type 1 and Larsen of Reunion Island syndrome. Growth retardation and ligamentous laxity are common manifestations of these syndromes.
Conclusions: We suggest that the identified mutation of equine B4GALT7 leads to the typical dwarfism phenotype in Friesian horses due to deficient splicing of transcripts of the gene. The mutated gene implicates the extracellular matrix in the regular organization of chrondrocyte columns of the growth plate. Conservation of individual amino acids may not be necessary at the protein level but instead may reflect underlying conservation of nucleotide sequence that are required for efficient splicing
Boost Invariance and Multiplicity Dependence of the Charge Balance Functionin and Collisions at GeV/c
Boost invariance and multiplicity dependence of the charge balance function
are studied in \pi^{+}\rp and \rK^{+}\rp collisions at 250 GeV/ incident
beam momentum. Charge balance, as well as charge fluctuations, are found to be
boost invariant over the whole rapidity region, but both depend on the size of
the rapidity window. It is also found that the balance function becomes
narrower with increasing multiplicity, consistent with the narrowing of the
balance function when centrality and/or system size increase, as observed in
current relativistic heavy ion experiments.Comment: 4 pages, 5 figures, Revte
Reaction mechanisms in 24Mg+12C and 32S+24Mg
The occurence of "exotic" shapes in light N=Z alpha-like nuclei is
investigated for 24Mg+12C and 32S+24Mg. Various approaches of superdeformed and
hyperdeformed bands associated with quasimolecular resonant structures with low
spin are presented. For both reactions, exclusive data were collected with the
Binary Reaction Spectrometer in coincidence with EUROBALL IV installed at the
VIVITRON Tandem facility of Strasbourg. Specific structures with large
deformation were selectively populated in binary reactions and their associated
-decays studied. The analysis of the binary and ternary reaction
channels is discussed.Comment: 7 pages, 4 figures, Paper presented at the Fusion08 International
Conference on New Aspects of Heavy Ion Collisions Near the Coulomb Barrier,
Chicago. Proceedings to be published by AIP Conference Proceedings Illinois,
USA, September 22-26, 200
A model for net-baryon rapidity distribution
In nuclear collisions, a sizable fraction of the available energy is carried
away by baryons. As the baryon number is conserved, the net-baryon
retains information on the energy-momentum carried by the incoming nuclei. A
simple and consistent model for net-baryon production in high energy
proton-proton and nucleus-nucleus collisions is presented. The basic
ingredients of the model are valence string formation based on standard PDFs
with QCD evolution and string fragmentation via the Schwinger mechanism. The
results of the model are presented and compared with data at different
centre-of-mass energies and centralities, as well as with existing models.
These results show that a good description of the main features of net-baryon
data is possible in the framework of a simplistic model, with the advantage of
making the fundamental production mechanisms manifest.Comment: 9 pages, 12 figures; in fig. 11 a) the vertical scale was correcte
Equivalence of Narcissistic Personality Inventory constructs and correlates across scoring approaches and response formats
The prevalent scoring practice for the Narcissistic Personality Inventory (NPI) ignores the forced-choice nature of the items. The aim of this study was to investigate whether findings based on NPI scores reported in previous research can be confirmed when the forced-choice nature of the NPI’s original response format is appropriately modeled, and when NPI items are presented in different response formats (true/false or rating scale). The relationships between NPI facets and various criteria were robust across scoring approaches (mean score vs. model-based), but were only partly robust across response formats. In addition, the scoring approaches and response formats achieved equivalent measurements of the vanity facet and in part of the leadership facet, but differed with respect to the entitlement facet
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