Socio-economic and social capital assessment of Avian Park residents, Worcester

At the beginning of every academic year, the Department of Sociology and Social Anthropology (hereafter Department), Stellenbosch University, takes Honours students on a research fieldtrip. The rationale is based on the need to provide Honours students with an in-service learning opportunity that entails fieldwork in an environment where their research efforts could make a contribution to community development. There is thus a dual objective: firstly, in-service learning through applied research using different research methodologies and secondly, the generation of new knowledge that could benefit community initiatives of various stakeholders. There is an additional third objective, namely to train community members in fieldwork skills in order for them to partake in similar studies. For 2011 Worcester and more specifically Avian Park (ward 13) was chosen as the research site. This site was selected partly because Stellenbosch University already has a community health project running in this area and there was both an interest and need for collaboration from the side of the Ukwanda Rural Clinical School in Worcester. Other University stakeholders included (in alphabetical order): Family Medicine, Human Nutrition, Occupational therapy, Physiotherapy, Speech, Language and Hearing therapy, Rehabilitation and Social Work. These stakeholders desired information about the community and some wanted to use the community volunteers trained by the Department for future research projects/interventions in the community

Figurationen des Porträts

Mit dem Fokus auf Figurationen des Porträts wird ein Spannungsfeld kulturellen Wissens eröffnet, anhand dessen sich der historische Bezugsraum von Artefakten diskutieren lässt. Porträt meint also nicht (nur) die kunsthistorische Gattung, sondern ein Wahrnehmungsmodell, das sich zwischen einmaliger Ausprägung und der Wiedererkennbarkeit der Form entfaltet. Die Studien zielen in einem Bogen vom frühesten (Herrscher-) Porträt aus dem Alten Mesopotamien bis in die Gegenwartskunst hinein auf historisch variable Formen, individuelles Leben als besonders darzustellen. Neben genuin bild- und skulpturorientierten Beiträgen von antiken Centauren-Porträts und Statuenbasen im kaiserzeitlichen Sagalassos über die ›Antike der Fotografie‹ bis hin zu Schwitters’ Merzbild 9b und Twomblys Selbstbildnissen behandeln textorientierte Beiträge Fragen der Lesbarkeit von Porträts, etwa in apokryphen Paulus-Texten, an der Schnittstelle von biographischem Porträt und byzantinischer Philosophie oder anhand von Poes Oval Portrait. Ein eigener Fokus gilt den kulturellen Praktiken der Bedeutungsstiftung, von Stalins Herrscherbildnissen bis hin zur anthropologischen Funktion beispielsweise von Masken

Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).

Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Socio-economic and social capital assessment of Avian Park residents, Worcester

At the beginning of every academic year, the Department of Sociology and Social Anthropology (hereafter Department), Stellenbosch University, takes Honours students on a research fieldtrip. The rationale is based on the need to provide Honours students with an in-service learning opportunity that entails fieldwork in an environment where their research efforts could make a contribution to community development. There is thus a dual objective: firstly, in-service learning through applied research using different research methodologies and secondly, the generation of new knowledge that could benefit community initiatives of various stakeholders. There is an additional third objective, namely to train community members in fieldwork skills in order for them to partake in similar studies. For 2011 Worcester and more specifically Avian Park (ward 13) was chosen as the research site. This site was selected partly because Stellenbosch University already has a community health project running in this area and there was both an interest and need for collaboration from the side of the Ukwanda Rural Clinical School in Worcester. Other University stakeholders included (in alphabetical order): Family Medicine, Human Nutrition, Occupational therapy, Physiotherapy, Speech, Language and Hearing therapy, Rehabilitation and Social Work. These stakeholders desired information about the community and some wanted to use the community volunteers trained by the Department for future research projects/interventions in the community

Adenoviral hepatitis in two Nile crocodile (Crocodylus niloticus) hatchlings from South Africa

Adenoviral infections may cause mild to severe morbidity or fatality in a large array of animal species. In crocodilians, hatchlings under 5 months of age are usually affected. However, there is a paucity of information on actual incidences in hatchlings originating from South Africa. Two cases of adenoviral hepatitis in crocodile hatchlings about 2 weeks old, bred on a commercial farm in South Africa, are described. Both hatchlings showed typical clinical signs of hepatitis. The identification of intranuclear inclusion bodies in the liver was used to differentiate between adenoviral hepatitis and chlamydial hepatitis. Although vertical transmission has never been proven in crocodiles, the young age of the affected hatchlings raises the possibility of vertical transmission. The lack of epidemiological information on adenoviral hepatitis in crocodiles highlights the need for further characterisation of the virus and targeted surveillance.http://www.jsava.co.za/index.php/jsavapm2020Anatomy and Physiolog