Utilização Simultânea de Vários Recursos para o Desenvolvimento de Competências Experimentais

O desenvolvimento de competências experimentais na área de Engenharia é fundamental, independentemente da área de aplicação.No entanto, nos cursos pós Bolonha, o número de horas de contacto foi significativamente reduzido, resultando naturalmente numa diminuição da carga laboratorial das várias unidades curriculares. Simultaneamente, o número de alunos por turma aumentou, não havendo, muitas vezes, equipamento em quantidade adequada, levando a que o tempo que o aluno realmente tem para “mexer” seja muito reduzido. Assim sendo, os alunos precisam de mais algum tempo para desenvolver, por si mesmos, estas competências e sedimentarem o conhecimento.A utilização de recursos online tais como laboratórios virtuais e laboratórios remotos é uma forma de colmatar esta falha e complementar o processo de ensino/aprendizagem, promovendo o desenvolvimento de competências experimentais. Este trabalho descreve sumariamente uma experiência didática levada a cabo no ISEP, na unidade curricular de Eletricidade, do 1º ano, 2º S da Licenciatura em Engenharia de Mecânica Automóvel (2013/14), na qual estavam inscritos 79 estudantes.info:eu-repo/semantics/publishedVersio

Prognostic Value of VEGF in Patients Submitted to Percutaneous Coronary Intervention

The authors gratefully acknowledge the assistance of the staff of Servico de Cardiologia, Hospital de Santa Marta, and Ms. Rute Pinheiro for the help with laboratory work. The study was financially supported by Fundacao para a Ciencia e Tecnologia, PIC/IC/82734/2007 Contract and SFRM/BPD/6308/2009 Grant, and by Liga dos Amigos do Hospital de Santa Marta.We examined the longitudinal changes of VEGF levels after percutaneous coronary intervention for predicting major adverse cardiac events (MACE) in coronary artery disease (CAD) patients. VEGF was measured in 94 CAD patients' serum before revascularization, 1-month and 1-year after. Independently of clinical presentation, patients had lower VEGF concentration than a cohort of healthy subjects (median, IQ: 15.9, 9.0-264 pg/mL versus 419, 212-758 pg/mL; P < 0.001) at baseline. VEGF increased to 1-month (median, IQ: 276, 167-498 pg/mL; P < 0.001) and remained steady to 1-year (median, IQ: 320, 173-497 pg/mL; P < 0.001) approaching control levels. Drug eluting stent apposition and previous medication intake produced a less steep VEGF evolution after intervention (P < 0.05). Baseline VEGF concentration <40.8 pg/mL conveyed increased risk for MACE in a 5-year follow-up. Results reflect a positive role of VEGF in recovery and support its importance in CAD prognosis.publishersversionpublishe

The VISIR+ Project – Helping Contextualize Math in an Engineering Course

[EN]The long-term goal of engineering education is to prepare students to work as engineers. Being a practical profession, laboratories play a crucial role in illustrating concepts and principles as well as improving technical skills. In the last decades the use of online resources (simulators and remote labs) has been growing, either as a complementary and/or as an alternative way of developing experimental competences. In the scope of the VISIR+ Project, this work presents the first results of a didactical implementation using simultaneously the remote laboratory VISIR (Virtual Instrument Systems in Reality), simulation and calculus in a Math Course at the Federal University of Santa Catarina (UFSC). The preliminary results indicate that the use of several resources increases students’ performance, boosting their learning and competence development

Amentadione is a new modulating agent for osteoarthritis in an ex-vivo co-culture preclinical assay

Osteoarthritis (OA) is a whole-joint disease where inflammation interplays with extracellular matrix mineralization in a cycle that leads to its degradation. The lack of effective preventing treatments and disease modifying agents, demands new therapeutic targets and development of effective drugs.FCT: SFRH/BD/111824/2015info:eu-repo/semantics/publishedVersio

Using TRAILER tool for Managing Informal Learning in academic and professional contexts: the learners’ perspective

Viegas, C., Marques, A., Alves, G., Zangrando, V., Galanis, N., Brouns, F., Janssen, J., Waszkiewicz, E., Mykowska, A., Gonzalez, M., Holgado, A., & García-Peñalvo, F. (2013). Using TRAILER tool for Managing Informal Learning in academic and professional contexts: the learners’ perspective. In F. J. García-Peñalvo (Ed.) Proceedings of the 2013 Conference on Technological Ecosystems for Enhancing Multiculturality. (pp. 529-534). November, 14-15, 2013, Salamanca, Spain.Informal Learning plays an important role in everyone's life and yet we often are unaware of it. The need to keep track of the knowledge acquired through informal learning is increasing as its sources become increasingly diverse. This paper presents a study on a tool developed to help keeping track of learners’ informal learning, both within academic and professional contexts, This tool, developed within the European Commission funded TRAILER project, will further integrate the improvements suggested by users during the piloting phase. The two studied contexts were similar regarding the importance and perception of Informal Learning, but differed concerning tool usage. The overall idea of managing one’s informal learning was well accepted and welcomed, which validated the emerging need for a tool with this purpose.Tagging, Recognition and Acknowledgment of Informal Learning ExpeRiences project (TRAILER) that is funded by the European Commission's Lifelong Learning Programme. Ref. 519141-LLP-1-2011-1-ES-KA3-KA3MP [http://www.trailerproject.eu]. This publication reflects the views only of the author, and the Commission cannot be held responsible for any use which may be made of the information contained therein

TRAILER: A Tool for Managing Informal Learning

Even though informal learning plays an important role in everyone’s life, not everyone is aware of its importance. These informal activities contribute to the development of self-regulated learning that can help productivity in different environments. As this kind of apprentices grow, the need to keep track of this developed knowledge is becoming vital. This paper presents a study on the perception and usage of a tool that would help keeping track of learners’ informal learning. This study was conducted both within academic and professional contexts and was developed within the European Commission funded TRAILER project. The contexts were similar regarding the importance and perception of informal learning, but differed concerning tool usage and the usefulness of such a platform. The overall idea of managing one’s informal learning was well accepted and welcomed, which validated the emerging need for a tool with this purpose

Amentadione from the Alga Cystoseira usneoides as a Novel Osteoarthritis Protective Agent in an Ex Vivo Co-Culture OA Model

Osteoarthritis (OA) remains a prevalent chronic disease without effective prevention and treatment. Amentadione (YP), a meroditerpenoid purified from the alga Cystoseira usneoides, has demonstrated anti-inflammatory activity. Here, we investigated the YP anti-osteoarthritic potential, by using a novel OA preclinical drug development pipeline designed to evaluate the anti-inflammatory and anti-mineralizing activities of potential OA-protective compounds. The workflow was based on in vitro primary cell cultures followed by human cartilage explants assays and a new OA co-culture model, combining cartilage explants with synoviocytes under interleukin-1 beta (IL-1 beta) or hydroxyapatite (HAP) stimulation. A combination of gene expression analysis and measurement of inflammatory mediators showed that the proposed model mimicked early disease stages, while YP counteracted inflammatory responses by downregulation of COX-2 and IL-6, improved cartilage homeostasis by downregulation of MMP3 and the chondrocytes hypertrophic differentiation factors Col10 and Runx2. Importantly, YP downregulated NF-kappa B gene expression and decreased phosphorylated IkB alpha/total IkB alpha ratio in chondrocytes. These results indicate the co-culture as a relevant pre-clinical OA model, and strongly suggest YP as a cartilage protective factor by inhibiting inflammatory, mineralizing, catabolic and differentiation processes during OA development, through inhibition of NF-kappa B signaling pathways, with high therapeutic potential

Psicologia da Educação no Instituto Superior de Engenharia do Porto: Projecto Caminhos de Bolonha

Este artigo apresenta a síntese da intervenção em Psicologia da Educação no Instituto Superior de Engenharia do Porto, no âmbito do Projecto Caminhos de Bolonha. O objectivo que norteia as actividades deste Projecto tem sido, desde o seu início, o apoio do Conselho Científico do ISEP na operacionalização do projecto de modernização e inovação do processo ensino aprendizagem no ISEP, induzido pela adesão ao processo de Bolonha.info:eu-repo/semantics/publishedVersio