11 research outputs found
Sex difference and intra-operative tidal volume: Insights from the LAS VEGAS study
- Author
- Adeline Gerard
- Adem Bytyqi
- Aggeliki Pandazi
- Ahmed Abdel-Razek
- Ahmed Chishti
- Ahmed Mostafa El-Shaarawy
- Alar Sormus
- Alastair Rose
- Albert Prades
- Alberto Lisi
- Alberto Zangrillo
- Aleksandra Lazukic
- Alena Breidablik
- Alenka Spindler-Vesel
- Alessandro Bacuzzi
- Alexander Kulikov
- Alexander Lugovoy
- Alexandre Molin
- Alexandru Bogdan Prodan
- Alexey Gritsan
- Alexey Ovezov
- Ali Saltali
- Alice Werger
- Alida Moise
- Alistair Cain
- Alyson Andrew
- Amanda Datson
- Ambra Licia Di Parma
- Amir Rafi
- Amir Shafi-Kabir
- Ana de Abajo Larriba
- Ana Fernandez- Bustamante
- Ana Maria Petcu
- Ana Pekle-Golez
- Ana Ricardo
- Andre Gottschalk
- Andrea Bell
- Andrea Brunelli
- Andrea Cortegiani
- Andreas Gueldner
- Andreas Reske
- Andrew Donovan
- Andrey Babayants
- Andrey Lubnin
- Andriy Grynyuk
- Andriy Mazur
- Anette Bundy
- Angela Almagro
- Angela Monteirosa
- Angelo Gratarola
- Ann De Bruyne
- Anna Fouracres
- Anna Marija Pavicic
- Annamaria Campanile
- Anne Duvekot
- Annika Aun
- Antoine Petit
- Antonella Marrella
- Antonino Giarratano
- Antonio Martínez Simon
- Antonio Zilic
- Antonis Andreou
- Arieh Eden
- Ashok Das
- Ashok Raj
- Audrey Pospiech
- Aurika Karbonskiene
- Bahar Kuvaki
- Barbka Novak-Supe
- Bas in ‘t Veld
- Baturay Kansu Kazbek
- Bea Bastin
- Ben Creagh-Brown
- Ben Schwerdtfeger
- Ben Shelley
- Benedikt Pannen
- Benoit Plichon
- Bernhard Urbanek
- Binnekade Jan M
- Bjorn Heyse
- Branka Maldini
- Branka Mazul-Sunko
- Branka Strazisar
- Branwen Ellison
- Brigitte Leva
- Cait Goodall
- Carlo Alberto Volta
- Carlos Ferrando
- Carlos Puigbo
- Catalin-Traian Guran
- Caterina Valeria Pesce
- Ceren Sanlikarip
- Cesar Aldecoa Alvares-Santullano
- Charley Higham
- Charlotte Severijns
- Christa Boer
- Christian Nestler
- Christopher Uhlig
- Christos Nouris
- Chryssa Pourzitaki
- Claire West
- Clare Jackson
- Colin Barrett
- Concezione Tommasino
- Corrado Liperi
- Cristina Saiz Ruiz
- Dalip Muhardri
- Dan Corneci
- Dan Costea
- Dana Tomescu
- Daniel Ferreira
- Daniela Filipescu
- Daniela La Bella
- Daniele Sances
- Danielle Franklin
- Darija Azenic-Venzera
- Daryl Kor
- David Kahn
- David Portch
- David Rogerson
- Davide D'antini
- Debbie Fuller
- Deborah Clements
- Dejana Djonoviċ- Omanoviċ
- Demet Sulemanji
- Denny Tran Thiem
- Diana Westerheide
- Dimitri Dylst
- Dimitrios Valsamidis
- Dimitris Karapanos
- Diogo Martins
- Dmitri Bystritski
- Dubravka Ivic
- Dunja Mihajlovic
- Egle Kontrimaviciute
- Eiko Herodes
- Elaine Rogers
- Elena Sardo
- Elisa Brugnoni
- Elisabeth Andersson
- Elizabeth Homan
- Elizabeth Luzier
- Emily Calton
- Emmanuel Futier
- Emmanuel Marret
- Emre Camci
- Enrique Moret
- Erick Morais
- Erika Salciute
- Ernesto Pastor
- Eyup Aydogan
- Fatma Mine Karaman
- Fatma Nur Akgun
- Fatos Sada
- Federica Scavonetto
- Felicity Mackenzie
- Ferim Gunenc
- Fernande Lois
- Fevzi Toraman
- Filippo Bressan
- Foteini Zafeiropoulou
- Francesca Montalto
- Francesca Rapido
- Francesco Bona
- Francis Joseph Borg
- Francisco Hidalgo Martinez
- Frederic Rodenas
- Frode Fjellanger
- Gabija Tomkute
- Gabriela Droc
- Gabriele Sales
- Galina Gritsan
- Gama de Abreu Marcelo
- Gary Mills
- Gary Minto
- Gecaj-Gashi Agreta
- Georgia Tsaousi
- Georgios Antholopoulos
- Georgios Gkiokas
- Gerd Struber
- Gianluca Castellani
- Gianluca Spano
- Gianmarco Giacoletto
- Gilda Cinnella
- Giorgia Cerati
- Giovanni Landoni
- Gisela Perez
- Giulia Pellerano
- Giuseppe Musella
- Giuseppe Servillo
- Glória Tareco
- Goncalves Castro
- Gorjana Erceg
- Guy Rousseau
- Hana Harazim
- Hans Gombotz
- Hany Yassin
- Hedenstierna Goran
- Helen Roberts
- Helen Scholes
- Helfried Metzler
- Hemmes Sabrine N T
- Hermann Wrigge
- Hiesmayr Michael
- Hisham Hosny Abdelwahab
- Hol Liselotte
- Hollmann Markus W
- Hrvoje Vinkovic
- Ib Jammer
- Ines Arpino
- Inga Mladic-Batinica
- Ioana Cristina Grintescu
- Ioana Marina Grintescu
- Ioana Popescu Garotescu
- Iole Brunetti
- Iorel Gherghina
- Irene Wiersma
- Irina Grosu
- Irina Komissarova
- Iulia Cindea
- Ivan Kostadinov
- Ivan Mirkovic
- Ivana Oputric
- Ivana Volfova
- Jaber Samir
- Jadranka Pavicic Saric
- Jale Maral
- James Limb
- Jan Brujevic
- Jan Poelaert
- Jane Montgomery
- Janet Palmer
- Jannicke Mellin-Olsen
- Jasmina Markovic-Bozi
- Jasmina Pejakovic
- Jasminka Kopic
- Jasper De Jong
- Jaume Canet
- Jayne Foot
- Jaysimha Susarla
- Jens Hering
- Jens Krassler
- Jeroen van Melkebeek
- Jesus Rico
- Jill Deane
- Joana Amaral
- Johann Geib
- John Williams
- John Xuereb
- Jonathan Paddle
- Jose Antonio de Andrés Ibañez
- Jose Tatay Vivo
- Josep Fava
- Josip Zunic
- Julie Colley
- Juraj Sprung
- Jurgen Van Limmen
- Juri Karjagin
- Juri Oganjan
- Kaili Sarapuu
- Kamil Hudacek
- Karen Simeson
- Karginova Zalina
- Kassiani Theodoraki
- Katarina Bruncakova
- Katarina Liskova
- Katerina Jirmanova
- Katerina Vitkova
- Katharina Skirstad Hodt
- Kazimir Juricic
- Konstantinos Stroumpoulis
- Krishnan Kodaganallur
- Lars Gillberg
- Laura Pasin
- Laura Pistidda
- Leanne Welch
- Lenka Polakovicova
- Liliana Mirea
- Lisa Wayman
- Luc De Baerdemaeker
- Luca Brazzi
- Luca Montagnani
- Lucia Mirabella
- Lucia Stancombe
- Lucia Zamidei
- Lucian Horhota
- Lucy Brown
- Luigi Beretta
- Luigi Delunas
- Luigi Giancarlo
- Luiz Fernando
- Lynn Everett
- Madalina Dutu
- Magda Riciu
- Mahdy Abdelhady
- Maka Zuleika
- Manuel Granell
- Manuel Vico Avalos
- Mar Sendra
- Marc Solier
- Marcel Gama de Abreu
- Marco Baciarello
- Marco Venturino
- Marco Verri
- Marcos Vidal Melo
- Marcus J
- Marcus Schultz
- Margaret Szewczyk
- Mari Carmen Unzueta
- Maria de Lurdes
- Maria Jose Yepes Temino
- Maria Nadolski
- Maria Vargas
- Maria Zelinkova
- Marian Irinel Tudoroiu
- Mariana Correia
- Marie-Claire van Malderen
- Marina Juros-Zovko
- Marina Soro
- Mario Defez
- Marios-Konstantinos Tasoulis
- Mark Pulletz
- Markus Hollmann
- Marta Eugenia Sassone
- Martin Scharffenberg
- Martin Weiss
- Martina Kosinova
- Matea Bogdanovic Dvorscak
- Matthew Rucklidge
- Maud Beran
- Maudrian Burton
- Maureen Bezzina
- Maurizio Solca
- Maximilian Schaefer
- Merilin Mall
- Michael Hiesmayr
- Michael Lundberg
- Michal Drab
- Michela Generali
- Michele De Michele
- Mihai Popescu
- Mihaly Veres
- Mills Gary H
- Minca Voje
- Mine Yildiz
- Mirja Konrad
- Mirna Sehovic
- Miroljub Jovanov
- Mladen Carev
- Mohamed Magdy
- Mohamed Mahran
- Mona Momeni
- Monir Jawad
- Moses Chikungwa
- Mrutyunjaya Rambhatla
- Murat Yilmaz
- Mónica Rodriguez Nunez
- Natalia Anipchenko
- Natasa Dropulic
- Nathalie Roels
- Necmiye Hadimioglu
- Nenad Karanovic
- Nesil Coskunfirat
- Neval Boztug
- Nicholas Boyd
- Nijbroek Sunny G
- Nukhet Sivrikoz
- Nuzhet Mert Senturk
- Oguzhan Arun
- Oleg Korolkov
- Olga Smekalova
- Onur Selvi
- Otto Mohr
- Ozgur Senturk
- Pablo Monedero
- Panagiota Florou
- Paola Morelli
- Paolo Pelosi
- Paolo Severgnini
- Parizade Raymode
- Pasquale Raimondo
- Patrice Forget
- Paul Dennesen
- Paula Dzurnakova
- Pauline Mercer
- Pavel Prokoshev
- Peeter Kivik
- Pelosi Paolo
- Petar Miskovic
- Peter Carvalho
- Peter Kienbaum
- Peter Spieth
- Petr Stourac
- Philip Watt
- Philipp Simon
- Piet Wyffels
- Povilas Miliauskas
- Putensen Christian
- Rachel Walker
- Radek Filipsky
- Radovan Dudas
- Raquel Martinez
- Renatas Tikuisis
- Reuven Pizov
- Riccardo Ragazzi
- Rienk van Beek
- Roberto Dossi
- Roberto Zoppellari
- Rocio Perez
- Rosanna Sileo
- Ruby Molina
- Rupert Pearse
- Ruta Aukstakalniene
- Ruxandra Copotoiu
- Ruxandra Fota
- Sabrine Hemmes
- Salvatore Grasso
- Samir el Kafraw
- Samir Jaber
- Sanda-Maria Copotoiu
- Sandeep Kusre
- Sandeep Varma
- Sandrine Damster
- Santi Maurizio Raineri
- Sara Rodrigues
- Sara Sher
- Sarah Gibb
- Sarah Moreton
- Savino Spadaro
- Schmid Werner
- Schultz
- Selma Pernar
- Semih Kucukguclu
- Semra Kucukgoncu
- Septimiu Gheorghe Moldovan
- Sergei Fedorov
- Sergiy Vorotyntsev
- Serpa Neto Ary
- Serpil Ustalar Ozgen
- Severgnini Paolo
- Seyda Canli
- Shivarajan Algarsamy
- Silvius Negoita
- Simon Davies
- Simone Merzky
- Sipylaite Jurate
- Slavica Kvolik
- Sofia Appleton
- Sonja Skiljic
- Sopio Peradze
- Stanley Wutai
- Stefan de Hert
- Stefan Ivars
- Stefano Pezzatto
- Stefano Tredici
- Stephanie Jones
- Stephen Mowat
- Stijn van de Velde
- Suat Sanli
- Sudhakar Marri
- Suresh Venkatesh
- Susan Yates
- Susana Cadilha
- Suzana Parente
- Swart Pien
- Tanja Goranovic
- Tanja Treschan
- Tarek Metwally
- Tatiana Sidiropoulou
- Tatyana Kapkan
- Thais Creary
- Thea Koch
- Thomas Bluth
- Thomas Kiss
- Thomas Smith
- Thomas Wegscheider
- Toby Weingarten
- Tom Jacobs
- Tomas Kolacek
- Tomislav Radocaj
- Valentina Tarzia
- Valery Likhvantsev
- Vedran Frkovic
- Veerle van Mossevelde
- Vesna Novak-Jankovic
- Vicari Sottosanti
- Victoria Barsan
- Victoria Moral
- Vidal Melo Marcos F
- Villiam Sobona
- Vincenzo Russotto
- Vittoria Bartolini
- Werner Schmid
- Wolfgang Kroell
- Wrigge Hermann
- Yeo Tze
- Yigal Leykin
- Yousif Saeed
- Zeljka Gavranovic
- Zerrin Sungur
- Zivile Teberaite
- Zsolt Tolcser
- Zuleyha Kazak Bengisun
- Zuzana Kusnierikova
- Şule Ozbilgin
- Publication venue
- 'Ovid Technologies (Wolters Kluwer Health)'
- Publication date
- 01/01/2021
- Field of study
BACKGROUND: One key element of lung-protective ventilation is the use of a low tidal volume (VT). A sex difference in use of low tidal volume ventilation (LTVV) has been described in critically ill ICU patients.OBJECTIVES: The aim of this study was to determine whether a sex difference in use of LTVV also exists in operating room patients, and if present what factors drive this difference.DESIGN, PATIENTS AND SETTING: This is a posthoc analysis of LAS VEGAS, a 1-week worldwide observational study in adults requiring intra-operative ventilation during general anaesthesia for surgery in 146 hospitals in 29 countries.MAIN OUTCOME MEASURES: Women and men were compared with respect to use of LTVV, defined as VT of 8 ml kg-1 or less predicted bodyweight (PBW). A VT was deemed 'default' if the set VT was a round number. A mediation analysis assessed which factors may explain the sex difference in use of LTVV during intra-operative ventilation.RESULTS: This analysis includes 9864 patients, of whom 5425 (55%) were women. A default VT was often set, both in women and men; mode VT was 500 ml. Median [IQR] VT was higher in women than in men (8.6 [7.7 to 9.6] vs. 7.6 [6.8 to 8.4] ml kg-1 PBW, P < 0.001). Compared with men, women were twice as likely not to receive LTVV [68.8 vs. 36.0%; relative risk ratio 2.1 (95% CI 1.9 to 2.1), P < 0.001]. In the mediation analysis, patients' height and actual body weight (ABW) explained 81 and 18% of the sex difference in use of LTVV, respectively; it was not explained by the use of a default VT.CONCLUSION: In this worldwide cohort of patients receiving intra-operative ventilation during general anaesthesia for surgery, women received a higher VT than men during intra-operative ventilation. The risk for a female not to receive LTVV during surgery was double that of males. Height and ABW were the two mediators of the sex difference in use of LTVV.TRIAL REGISTRATION: The study was registered at Clinicaltrials.gov, NCT01601223
The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis
- Author
- Abbott TEF
- Abdel Razzaq Khalaf
- Agostino Roasio
- Ahmad T
- Akram Fuad
- Alberto Premoli
- Alberto Zangrillo
- Alessandra Bettinelli
- Alessandro Gatta
- Alessandro Marchesi
- Andrea Sibilio
- Angelantonio Pascazio
- Angelo Benevento
- Antonio Baroselli
- Antonio Colangelo
- Antonio Pata
- Biccard BM
- Burair Geddoa
- Carla Tinti
- Chew MS
- Chiara Alloj
- Chiara Colangelo
- Christian Gastaldi
- Cloro Paolo Maria
- Corrado Bottini
- Daiana Taddeo
- Daniele Corti
- Dario Winterton
- Elena Bignami
- Elena Moizo
- Eleonora Costanzo
- Elisa Copetti
- Emilio Pozzi
- Federico Ghignone
- Fowler AJ
- Francesco Pata
- Furquan Pathan
- Gaetano Tessera
- Giacomo Monti
- Giampaolo Ugolini
- Gilberto Poggioli
- Gillies M
- Giovanni Landoni
- Giuseppe Rotunno
- Hadi Awad
- Hewson R
- Ilaria Toretti
- International Surgical Outcomes Study (ISOS) group Neil Waworuntu
- James Joseph
- Livio Carmino
- Lorenzo Spagnesi
- Luca Boschi
- Luca Cabrini
- Lucia Caterina Fanfani
- Luigi Beretta
- Luigi Giancarlo
- Luigi Maria Cloro
- Maithem Kenber
- Margherita Pintaudi
- Maria Teresa Novelli
- Mario Arrigo
- Mario Taffurelli
- Mattia Bellandi
- Maurizio Cannavo'
- Mauro Nastasi
- Miguel Angel Paludi
- Mohd Azuan Ab Majid
- Pearse RM
- Phull MK
- Roberta Meroni
- Rocco D'Andrea
- Rusnah Ab Rahman
- Sabah Al Hussaini
- Safauldeensalem Albaj
- Savino Spadaro
- Silvano Cardellino
- Speranza Bocchino
- Valentina Paola Plumari
- Valentina Testa
- Vicari Sottosanti
- Vieri Parrini
- Volta CA
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool.
Methods: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals.
Results: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32-0.77); P<0.01], but no difference in complication rates [OR 1.02 (0.88-1.19); P=0.75]. In a systematic review, we screened 3732 records and identified 11 eligible studies of 453 292 patients including the ISOS cohort. Checklist exposure was associated with both reduced postoperative mortality [OR 0.75 (0.62-0.92); P<0.01; I2=87%] and reduced complication rates [OR 0.73 (0.61-0.88); P<0.01; I2=89%).
Conclusions: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine
Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study
- Author
- Adeline Gerard
- Adem Bytyqi
- Aggeliki Pandazi
- Agreta Gecaj-Gashi
- Ahmed Abdel-Razek
- Ahmed Chishti
- Ahmed Gouda Ahmed
- Ahmed Mostafa El-Shaarawy
- Alar Sormus
- Alastair Rose
- Albert Prades
- Alberto Lisi
- Alberto Zangrillo
- Aleksandra Lazukic
- Alena Breidablik
- Alenka Spindler-Vesel
- Alessandro Bacuzzi
- Alexander Kulikov
- Alexander Lugovoy
- Alexandre Molin
- Alexandru Bogdan Prodan
- Alexey Gritsan
- Alexey Ovezov
- Ali Saltali
- Alice Werger
- Alida Moise
- Alistair Cain
- Alyson Andrew
- Amanda Datson
- Ambra Licia Di Parma
- Amir Rafi
- Amir Shafi-Kabiri
- Ana de Abajo Larriba
- Ana Fernandez-Bustamante
- Ana Maria Petcu
- Ana Pekle-Golez
- Ana Ricardo
- Andre Gottschalk
- Andrea Bell
- Andrea Brunelli
- Andrea Cortegiani
- Andreas Gueldner
- Andreas Reske
- Andrew Donovan
- Andrey Babayants
- Andrey Lubnin
- Andriy Grynyuk
- Andriy Mazur
- Anette Bundy
- Angela Almagro
- Angela Monteirosa
- Angelo Gratarola
- Ann De Bruyne
- Anna Fouracres
- Anna Marija Pavicic
- Annamaria Campanile
- Anne Duvekot
- Annika Aun
- Antoine Petit
- Antonella Marrella
- Antonino Giarratano
- Antonio Martínez Simon
- Antonio Zilic
- Antonis Andreou
- Arieh Eden
- Ashok Das
- Ashok Raj
- Audrey Pospiech
- Aurika Karbonskiene
- Bahar Kuvaki
- Ball L
- Barbka Novak-Supe
- Bas In 't Veld
- Battaglini D
- Baturay Kansu Kazbek
- Bea Bastin
- Ben Creagh-Brown
- Ben Schwerdtfeger
- Ben Shelley
- Benedikt Pannen
- Benoit Plichon
- Bernhard Urbanek
- Bjorn Heyse
- Bluth T
- Branka Maldini
- Branka Mazul-Sunko
- Branka Strazisar
- Branwen Ellison
- Brigitte Leva
- Cait Goodall
- Canet J
- Carlo Alberto Volta
- Carlos Ferrando
- Carlos Puigbo
- Catalin-Traian Guran
- Caterina Valeria Pesce
- Ceren Sanlikarip
- Cesar Aldecoa Alvares-Santullano
- Charley Higham
- Charlotte Severijns
- Christa Boer
- Christian Nestler
- Christopher Uhlig
- Christos Nouris
- Chryssa Pourzitaki
- Claire West
- Clare Jackson
- Colin Barrett
- Concezione Tommasino
- Corrado Liperi
- Cristina Saiz Ruiz
- Dalip Muhardri
- Dan Corneci
- Dan Costea
- Dana Tomescu
- Daniel Ferreira
- Daniela Filipescu
- Daniela La Bella
- Daniele Sances
- Danielle Franklin
- Darija Azenic-Venzera
- Daryl Kor
- David Kahn
- David Portch
- David Rogerson
- Davide D'antini
- Debbie Fuller
- Deborah Clements
- Dejana Djonoviċ-Omanoviċ
- Demet Sulemanji
- Denny Tran Thiem
- Diana Westerheide
- Dimitri Dylst
- Dimitrios Valsamidis
- Dimitris Karapanos
- Diogo Martins
- Dmitri Bystritski
- Dubravka Ivic
- Dunja Mihajlovic
- Egle Kontrimaviciute
- Eiko Herodes
- Elaine Rogers
- Elena Sardo
- Elisa Brugnoni
- Elisabeth Andersson
- Elizabeth Homan
- Elizabeth Luzier
- Emily Calton
- Emmanuel Futier
- Emmanuel Marret
- Emre Camci
- Enrique Moret
- Erick Morais
- Erika Salciute
- Ernesto Pastor
- Eyup Aydogan
- Fatma Mine Karaman
- Fatma Nur Akgun
- Fatos Sada
- Federica Scavonetto
- Felicity Mackenzie
- Ferim Gunenc
- Fernande Lois
- Fevzi Toraman
- Filippo Bressan
- Foteini Zafeiropoulou
- Francesca Montalto
- Francesca Rapido
- Francesco Bona
- Francis Joseph Borg
- Francisco Hidalgo Martinez
- Frederic Rodenas
- Frode Fjellanger
- Gabija Tomkute
- Gabriela Droc
- Gabriele Sales
- Galina Gritsan
- Gama de Abreu M
- Gary Mills
- Gary Minto
- Georgia Tsaousi
- Georgios Antholopoulos
- Georgios Gkiokas
- Gerd Struber
- Gianluca Castellani
- Gianluca Spano
- Gianmarco Giacoletto
- Gilda Cinnella
- Giorgia Cerati
- Giovanni Landoni
- Gisela Perez
- Giulia Pellerano
- Giuseppe Musella
- Giuseppe Servillo
- Glória Tareco
- Gorjana Erceg
- Guy Rousseau
- Hana Harazim
- Hans Gombotz
- Hany Yassin
- Helen Nutt
- Helen Roberts
- Helen Scholes
- Helfried Metzler
- Hemmes SNT
- Hermann Wrigge
- Hiesmayr M
- Hisham Hosny Abdelwahab
- Hollmann MW
- Hrvoje Vinkovic
- Ib Jammer
- Ines Arpino
- Inga Mladic-Batinica
- Ioana Cristina Grintescu
- Ioana Marina Grintescu
- Ioana Popescu Garotescu
- Iole Brunetti
- Iorel Gherghina
- Irene Wiersma
- Irina Grosu
- Irina Komissarova
- Iulia Cindea
- Ivan Kostadinov
- Ivan Mirkovic
- Ivana Oputric
- Ivana Volfova
- Jaber S
- Jadranka Pavicic Saric
- Jale Maral
- James Limb
- Jan Binnekade
- Jan Brujevic
- Jan Poelaert
- Jane Montgomery
- Janet Palmer
- Jannicke Mellin-Olsen
- Jasmina Markovic-Bozic
- Jasmina Pejakovic
- Jasminka Kopic
- Jasper De Jong
- Jaume Canet
- Jayne Foot
- Jaysimha Susarla
- Jens Hering
- Jens Krassler
- Jeroen van Melkebeek
- Jesus Rico
- Jill Deane
- Joana Amaral
- Johann Geib
- John Williams
- John Xuereb
- Jonathan Paddle
- Jose Antonio de Andrés Ibañez
- Jose Tatay Vivo
- Josep Fava
- Josip Zunic
- Julie Colley
- Juraj Sprung
- Jurgen Van Limmen
- Juri Karjagin
- Juri Oganjan
- Kaili Sarapuu
- Kamil Hudacek
- Karen Simeson
- Karginova Zalina
- Kassiani Theodoraki
- Katarina Bruncakova
- Katarina Liskova
- Katerina Jirmanova
- Katerina Vitkova
- Katharina Skirstad Hodt
- Kazimir Juricic
- Konstantinos Stroumpoulis
- Krishnan Kodaganallur
- Lars Gillberg
- Laura Pasin
- Laura Pistidda
- Leanne Welch
- Lenka Polakovicova
- Lieuwe Bos
- Liliana Mirea
- Lisa Wayman
- Luc De Baerdemaeker
- Luca Brazzi
- Luca Montagnani
- Lucia Mirabella
- Lucia Stancombe
- Lucia Zamidei
- Lucian Horhota
- Lucy Brown
- Luigi Beretta
- Luigi Delunas
- Luigi Giancarlo
- Luiz Fernando
- Lynn Everett
- Madalina Dutu
- Magda Riciu
- Mahdy Abdelhady
- Maka Zuleika
- Manuel Granell
- Manuel Vico Avalos
- Mar Sendra
- Marc Solier
- Marcel Gama de Abreu
- Marco Baciarello
- Marco Venturino
- Marco Verri
- Marcos Vidal Melo
- Marcus Schultz
- Margaret Szewczyk
- Mari Carmen Unzueta
- Maria de Lurdes Goncalves Castro
- Maria Jose Yepes Temino
- Maria Nadolski
- Maria Vargas
- Maria Zelinkova
- Marian Irinel Tudoroiu
- Mariana Correia
- Marie-Claire van Malderen
- Marina Juros-Zovko
- Marina Soro
- Mario Defez
- Marios-Konstantinos Tasoulis
- Mark Pulletz
- Markus Hollmann
- Marta Eugenia Sassone
- Martin Scharffenberg
- Martin Weiss
- Martina Kosinova
- Matea Bogdanovic Dvorscak
- Matthew Rucklidge
- Maud Beran
- Maudrian Burton
- Maureen Bezzina
- Maurizio Solca
- Maximilian Schaefer
- Merilin Mall
- Michael Hiesmayr
- Michael Lundberg
- Michal Drab
- Michela Generali
- Michele De Michele
- Mihai Popescu
- Mihaly Veres
- Mills GH
- Minca Voje
- Mine Yildiz
- Mirja Konrad
- Mirna Sehovic
- Miroljub Jovanov
- Mladen Carev
- Mohamed Magdy
- Mohamed Mahran
- Mona Momeni
- Monir Jawad
- Moses Chikungwa
- Mrutyunjaya Rambhatla
- Murat Yilmaz
- Mónica Rodriguez Nunez
- Natalia Anipchenko
- Natasa Dropulic
- Nathalie Roels
- Necmiye Hadimioglu
- Nenad Karanovic
- Nesil Coskunfirat
- Neval Boztug
- Nicholas Boyd
- Nukhet Sivrikoz
- Nuzhet Mert Senturk
- Oguzhan Arun
- Oleg Korolkov
- Olga Smekalova
- Onur Selvi
- Otto Mohr
- Ozgur Senturk
- Pablo Monedero
- Panagiota Florou
- Paola Morelli
- Paolo Pelosi
- Paolo Severgnini
- Parizade Raymode
- Pasquale Raimondo
- Patrice Forget
- Paul Dennesen
- Paula Dzurnakova
- Pauline Mercer
- Pavel Prokoshev
- Peeter Kivik
- Pelosi P
- Petar Miskovic
- Peter Carvalho
- Peter Kienbaum
- Peter Spieth
- Petr Stourac
- Philip Watt
- Philipp Simon
- Piet Wyffels
- Povilas Miliauskas
- Putensen C
- Rachel Walker
- Radek Filipsky
- Radovan Dudas
- Raquel Martinez
- Renatas Tikuisis
- Reuven Pizov
- Riccardo Ragazzi
- Rienk van Beek
- Robba C
- Roberto Dossi
- Roberto Zoppellari
- Rocio Perez
- Rosanna Sileo
- Ruby Molina
- Rupert Pearse
- Ruta Aukstakalniene
- Ruxandra Copotoiu
- Ruxandra Fota
- Sabrine Hemmes
- Salvatore Grasso
- Samir El Kafrawy
- Samir Jaber
- Sanda-Maria Copotoiu
- Sandeep Kusre
- Sandeep Varma
- Sandrine Damster
- Santi Maurizio Raineri
- Sara Rodrigues
- Sara Sher
- Sarah Gibb
- Sarah Moreton
- Savino Spadaro
- Schmid W
- Schultz MJ
- Selma Pernar
- Semih Kucukguclu
- Semra Kucukgoncu
- Septimiu Gheorghe Moldovan
- Sergei Fedorov
- Sergiy Vorotyntsev
- Serpa Neto A
- Serpil Ustalar Ozgen
- Severgnini P
- Seyda Canli
- Shivarajan Algarsamy
- Silvius Negoita
- Simon Davies
- Simone Merzky
- Sipylaite Jurate
- Slavica Kvolik
- Sofia Appleton
- Sonja Skiljic
- Sopio Peradze
- Stanley Wutai
- Stefan de Hert
- Stefan Ivars
- Stefano Pezzatto
- Stefano Tredici
- Stephanie Jones
- Stephen Mowat
- Stijn van de Velde
- Suat Sanli
- Sudhakar Marri
- Suresh Venkatesh
- Susan Yates
- Susana Cadilha
- Suzana Parente
- Tanja Goranovic
- Tanja Treschan
- Tarek Metwally
- Tatiana Sidiropoulou
- Tatyana Kapkan
- Thais Creary
- Thea Koch
- Thomas Bluth
- Thomas Kiss
- Thomas Smith
- Thomas Wegscheider
- Toby Weingarten
- Tom Jacobs
- Tomas Kolacek
- Tomislav Radocaj
- Valentina Tarzia
- Valery Likhvantsev
- Vedran Frkovic
- Veerle van Mossevelde
- Vesna Novak-Jankovic
- Vicari Sottosanti
- Victoria Barsan
- Victoria Moral
- Vidal Melo MF
- Villiam Sobona
- Vincenzo Russotto
- Vittoria Bartolini
- Wael Fathy Hasan
- Werner Schmid
- Wolfgang Kroell
- Wrigge H
- Yeo Tze
- Yigal Leykin
- Yousif Saeed
- Zeljka Gavranovic
- Zerrin Sungur
- Zivile Teberaite
- Zsolt Tolcser
- Zuleyha Kazak Bengisun
- Zuzana Kusnierikova
- Şule Ozbilgin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
Background: Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings of patients undergoing neurosurgical procedures, and to explore the association between perioperative variables and the development of PPCs in neurosurgical patients.
Methods: Post-hoc analysis of LAS VEGAS study, restricted to patients undergoing neurosurgery. Patients were stratified into groups based on the type of surgery (brain and spine), the occurrence of PPCs and the assess respiratory risk in surgical patients in Catalonia (ARISCAT) score risk for PPCs.
Results: Seven hundred eighty-four patients were included in the analysis; 408 patients (52%) underwent spine surgery and 376 patients (48%) brain surgery. Median tidal volume (VT) was 8 ml [Interquartile Range, IQR = 7.3-9] per predicted body weight; median positive end-expiratory pressure (PEEP) was 5 [3 to 5] cmH20. Planned recruitment manoeuvres were used in the 6.9% of patients. No differences in ventilator settings were found among the sub-groups. PPCs occurred in 81 patients (10.3%). Duration of anaesthesia (odds ratio, 1.295 [95% confidence interval 1.067 to 1.572]; p = 0.009) and higher age for the brain group (odds ratio, 0.000 [0.000 to 0.189]; p = 0.031), but not intraoperative ventilator settings were independently associated with development of PPCs.
Conclusions: Neurosurgical patients are ventilated with low VT and low PEEP, while recruitment manoeuvres are seldom applied. Intraoperative ventilator settings are not associated with PPCs
Association between night-time surgery and occurrence of intraoperative adverse events and postoperative pulmonary complications
- Author
- Abdel-Razek Ahmed
- Abdelhady Mahdy
- Abdelwahab Hisham Hosny
- Ahmed Ahmed Gouda
- Akgun Fatma Nur
- Aldecoa Alvares-Santullano Cesar
- Algarsamy Shivarajan
- Almagro Angela
- Amaral Joana
- Andersson Elisabeth
- Andreou Antonis
- Andrew Alyson
- Anipchenko Natalia
- Antholopoulos Georgios
- Appleton Sofia
- Arpino Ines
- Arun Oguzhan
- Aukstakalniene Ruta
- Aun Annika
- Avalos Manuel Vico
- Aydogan Eyup
- Azenic-Venzera Darija
- Babayants Andrey
- Baciarello Marco
- Bacuzzi Alessandro
- Ball L
- Barrett Colin
- Barsan Victoria
- Bartolini Vittoria
- Bastin Bea
- Bell Andrea
- Bengisun Zuleyha Kazak
- Beran Maud
- Beretta Luigi
- Bezzina Maureen
- Binnekade Jan
- Bluth Thomas
- Boer Christa
- Bona Francesco
- Borg Francis Joseph
- Bos Lieuwe
- Boyd Nicholas
- Boztug Neval
- Brazzi Luca
- Breidablik Alena
- Bressan Filippo
- Brown Lucy
- Brugnoni Elisa
- Brujevic Jan
- Bruncakova Katarina
- Brunelli Andrea
- Brunetti Iole
- Bundy Anette
- Burton Maudrian
- Bystritski Dmitri
- Bytyqi Adem
- Cadilha Susana
- Cain Alistair
- Calton Emily
- Camci Emre
- Campanile Annamaria
- Canet J
- Canli Seyda
- Carev Mladen
- Carmen Unzueta Mari
- Carvalho Peter
- Castellani Gianluca
- Cerati Giorgia
- Chikungwa Moses
- Chishti Ahmed
- Cindea Iulia
- Cinnella Gilda
- Clements Deborah
- Colley Julie
- Copotoiu Ruxandra
- Copotoiu Sanda-Maria
- Corneci Dan
- Correia Mariana
- Cortegiani A
- Coskunfirat Nesil
- Costea Dan
- Creagh-Brown Ben
- Creary Thais
- D'antini Davide
- Damster Sandrine
- Das Ashok
- Datson Amanda
- Davies Simon
- de Abajo Larriba Ana
- de Andres Ibanez Jose Antonio
- De Baerdemaeker Luc
- De Bruyne Ann
- De Hert Stefan
- De Jong Jasper
- De Michele Michele
- Deane Jill
- Defez Mario
- Delunas Luigi
- Dennesen Paul
- Di Parma Ambra Licia
- Djonovic-Omanovic Dejana
- Donovan Andrew
- Dossi Roberto
- Drab Michal
- Droc Gabriela
- Dropulic Natasa
- Dudas Radovan
- Dutu Madalina
- Duvekot Anne
- Dvorscak Matea Bogdanovic
- Dylst Dimitri
- Dzurnakova Paula
- Eden Arieh
- el Kafrawy Samir
- El-Shaarawy Ahmed Mostafa
- Ellison Branwen
- Erceg Gorjana
- Everett Lynn
- Fava Josep
- Fedorov Sergei
- Fernandez-Bustamante Ana
- Fernando Luiz
- Ferrando Carlos
- Ferreira Daniel
- Filipescu Daniela
- Filipsky Radek
- Fjellanger Frode
- Florou Panagiota
- Foot Jayne
- Forget Patrice
- Fota Ruxandra
- Fouracres Anna
- Franklin Danielle
- Frkovic Vedran
- Fuller Debbie
- Futier Emmanuel
- Gama de Abreu M
- Garotescu Ioana Popescu
- Gavranovic Zeljka
- Gecaj-Gashi Agreta
- Geib Johann
- Generali Michela
- Gerard Adeline
- Gherghina Iorel
- Giacoletto Gianmarco
- Giarratano Antonino
- Gibb Sarah
- Gillberg Lars
- Gkiokas Georgios
- Gombotz Hans
- Goncalves Castro Maria de Lurdes
- Goodall Cait
- Goranovic Tanja
- Gottschalk Andre
- Granell Manuel
- Grasso Salvatore
- Gratarola Angelo
- Gregoretti C
- Grintescu Ioana Cristina
- Grintescu Ioana Marina
- Gritsan Alexey
- Gritsan Galina
- Grosu Irina
- Grynyuk Andriy
- Gueldner Andreas
- Gunenc Ferim
- Guran Catalin-Traian
- Hadimioglu Necmiye
- Harazim Hana
- Hasan Wael Fathy
- Hemmes Sabrine
- Hemmes SNT
- Hering Jens
- Herodes Eiko
- Heyse Bjorn
- Hidalgo Martinez Francisco
- Hiesmayr M
- Hiesmayr Michael
- Higham Charley
- Hodt Katharina Skirstad
- Hollmann Markus
- Hollmann MW
- Homan Elizabeth
- Horhota Lucian
- Hudacek Kamil
- in 't Veld Bas
- Ivars Stefan
- Ivic Dubravka
- Jaber Samir
- Jackson Clare
- Jacobs Tom
- Jammer Ib
- Jawad Monir
- Jirmanova Katerina
- Jones Stephanie
- Jovanov Miroljub
- Jurate Sipylaite
- Juricic Kazimir
- Juros-Zovko Marina
- Kahn David
- Kapkan Tatyana
- Karaman Fatma Mine
- Karanovic Nenad
- Karapanos Dimitris
- Karbonskiene Aurika
- Karjagin Juri
- Kazbek Baturay Kansu
- Kienbaum Peter
- Kiss Thomas
- Kivik Peeter
- Koch Thea
- Kodaganallur Krishnan
- Kolacek Tomas
- Komissarova Irina
- Konrad Mirja
- Kontrimaviciute Egle
- Kopic Jasminka
- Kor Daryl
- Korolkov Oleg
- Kosinova Martina
- Kostadinov Ivan
- Krassler Jens
- Kroell Wolfgang
- Kucukgoncu Semra
- Kucukguclu Semih
- Kulikov Alexander
- Kusnierikova Zuzana
- Kusre Sandeep
- Kuvaki Bahar
- Kvolik Slavica
- La Bella Daniela
- Landoni Giovanni
- Lazukic Aleksandra
- Leva Brigitte
- Leykin Yigal
- Likhvantsev Valery
- Limb James
- Liperi Corrado
- Lisi Alberto
- Liskova Katarina
- Lois Fernande
- Lubnin Andrey
- Lugovoy Alexander
- Lundberg Michael
- Luzier Elizabeth
- Mackenzie Felicity
- Magdy Mohamed
- Mahran Mohamed
- Maldini Branka
- Mall Merilin
- Maral Jale
- Markovic-Bozic Jasmina
- Marrella Antonella
- Marret Emmanuel
- Marri Sudhakar
- Martinez Simon Antonio
- Martinez Raquel
- Martins Diogo
- Mazul-Sunko Branka
- Mazur Andriy
- Mellin-Olsen Jannicke
- Melo Marcos Vidal
- Melo MFV
- Mercer Pauline
- Merzky Simone
- Metwally Tarek
- Metzler Helfried
- Mihajlovic Dunja
- Miliauskas Povilas
- Mills Gary
- Mills GH
- Minto Gary
- Mirabella Lucia
- Mirea Liliana
- Mirkovic Ivan
- Miskovic Petar
- Mladic-Batinica Inga
- Mohr Otto
- Moise Alida
- Moldovan Septimiu Gheorghe
- Molin Alexandre
- Molina Ruby
- Momeni Mona
- Monedero Pablo
- Montagnani Luca
- Montalto Francesca
- Monteirosa Angela
- Montgomery Jane
- Morais Erick
- Moral Victoria
- Morelli Paola
- Moret Enrique
- Moreton Sarah
- Mowat Stephen
- Muhardri Dalip
- Musella Giuseppe
- Nadolski Maria
- Negoita Silvius
- Nestler Christian
- Neto AS
- Nouris Christos
- Novak-Jankovic Vesna
- Novak-Supe Barbka
- Nutt Helen
- Oganjan Juri
- Oputric Ivana
- Ovezov Alexey
- Ozbilgin Sule
- Ozgen Serpil Ustalar
- Paddle Jonathan
- Palmer Janet
- Pandazi Aggeliki
- Pannen Benedikt
- Parente Suzana
- Pasin Laura
- Pastor Ernesto
- Pavicic Anna Marija
- Pearse Rupert
- Pejakovic Jasmina
- Pekle-Golez Ana
- Pellerano Giulia
- Pelosi P
- Peradze Sopio
- Perez Gisela
- Perez Rocio
- Pernar Selma
- Pesce Caterina Valeria
- Petcu Ana Maria
- Petit Antoine
- Pezzatto Stefano
- Pistidda Laura
- Pizov Reuven
- Plichon Benoit
- Poelaert Jan
- Polakovicova Lenka
- Popescu Mihai
- Portch David
- Pospiech Audrey
- Pourzitaki Chryssa
- Prades Albert
- Prodan Alexandru Bogdan
- Prokoshev Pavel
- Puigbo Carlos
- Pulletz Mark
- Putensen C
- Radocaj Tomislav
- Rafi Amir
- Ragazzi Riccardo
- Raimondo Pasquale
- Raineri Santi Maurizio
- Raj Ashok
- Rambhatla Mrutyunjaya
- Rapido Francesca
- Raymode Parizade
- Reske Andreas
- Ricardo Ana
- Riciu Magda
- Rico Jesus
- Roberts Helen
- Rodenas Frederic
- Rodrigues Sara
- Rodriguez Nunez Monica
- Roels Nathalie
- Rogers Elaine
- Rogerson David
- Rose Alastair
- Rousseau Guy
- Rucklidge Matthew
- Russotto Vincenzo
- Sada Fatos
- Saeed Yousif
- Saiz Ruiz Cristina
- Salciute Erika
- Sales Gabriele
- Saltali Ali
- Sances Daniele
- Sanli Suat
- Sanlikarip Ceren
- Sarapuu Kaili
- Sardo Elena
- Saric Jadranka Pavicic
- Sassone Marta Eugenia
- Scavonetto Federica
- Schaefer Maximilian
- Scharffenberg Martin
- Schmid W
- Schmid Werner
- Scholes Helen
- Schultz Marcus
- Schultz MJ
- Schwerdtfeger Ben
- Sehovic Mirna
- Selvi Onur
- Sendra Mar
- Senturk Nuzhet Mert
- Senturk Ozgur
- Servillo Giuseppe
- Severgnini P
- Severgnini Paolo
- Severijns Charlotte
- Shafi-Kabiri Amir
- Shelley Ben
- Sher Sara
- Sidiropoulou Tatiana
- Sileo Rosanna
- Simeson Karen
- Simon Philipp
- Sivrikoz Nukhet
- Skiljic Sonja
- Smekalova Olga
- Smith Thomas
- Sobona Villiam
- Solca Maurizio
- Solier Marc
- Sormus Alar
- Soro Marina
- Sottosanti Luigi Giancarlo Vicari
- Spadaro Savino
- Spano Gianluca
- Spieth Peter
- Spindler-Vesel Alenka
- Sprung Juraj
- Stancombe Lucia
- Stourac Petr
- Strazisar Branka
- Stroumpoulis Konstantinos
- Struber Gerd
- Sulemanji Demet
- Sungur Zerrin
- Susarla Jaysimha
- Szewczyk Margaret
- Tareco Gloria
- Tarzia Valentina
- Tasoulis Marios-Konstantinos
- Tatay Vivo Jose
- Teberaite Zivile
- Theodorak Kassiani
- Thiem Denny Tran
- Tikuisis Renatas
- Tolcser Zsolt
- Tomescu Dana
- Tomkute Gabija
- Tommasino Concezione
- Toraman Fevzi
- Tredici Stefano
- Treschan Tanja
- Tsaousi Georgia
- Tudoroiu Marian Irinel
- Tze Yeo
- Uhlig Christopher
- Urbanek Bernhard
- Valsamidis Dimitrios
- van Beek Rienk
- van de Velde Stijn
- Van Limmen Jurgen
- van Malderen Marie-Claire
- van Melkebeek Jeroen
- van Mossevelde Veerle
- Vargas Maria
- Varma Sandeep
- Venkatesh Suresh
- Venturino Marco
- Veres Mihaly
- Verri Marco
- Vinkovic Hrvoje
- Vitkova Katerina
- Voje Minca
- Volfova Ivana
- Volta Carlo Alberto
- Vorotyntsev Sergiy
- Walker Rachel
- Watt Philip
- Wayman Lisa
- Wegscheider Thomas
- Weingarten Toby
- Weiss Martin
- Welch Leanne
- Werger Alice
- West Claire
- Westerheide Diana
- Wiersma Irene
- Williams John
- Wrigge H
- Wrigge Hermann
- Wutai Stanley
- WYFFELS PIET
- Xuereb John
- Yassin Hany
- Yates Susan
- Yepes Temino Maria Jose
- Yildiz Mine
- Yilmaz Murat
- Zafeiropoulou Foteini
- Zalina Karginova
- Zamidei Lucia
- Zangrillo Alberto
- Zelinkova Maria
- Zilic Antonio
- Zoppellari Roberto
- Zuleika Maka
- Zunic Josip
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background: The aim of this post hoc analysis of a large cohort study was to evaluate the association between night-time surgery and the occurrence of intraoperative adverse events (AEs) and postoperative pulmonary complications (PPCs).
Methods: LAS VEGAS (Local Assessment of Ventilatory Management During General Anesthesia for Surgery) was a prospective international 1-week study that enrolled adult patients undergoing surgical procedures with general anaesthesia and mechanical ventilation in 146 hospitals across 29 countries. Surgeries were defined as occurring during 'daytime' when induction of anaesthesia was between 8: 00 AM and 7: 59 PM, and as 'night-time' when induction was between 8: 00 PM and 7: 59 AM.
Results: Of 9861 included patients, 555 (5.6%) underwent surgery during night-time. The proportion of patients who developed intraoperative AEs was higher during night-time surgery in unmatched (43.6% vs 34.1%; P<0.001) and propensity-matched analyses (43.7% vs 36.8%; P = 0.029). PPCs also occurred more often in patients who underwent night-time surgery (14% vs 10%; P = 0.004) in an unmatched cohort analysis, although not in a propensity-matched analysis (13.8% vs 11.8%; P = 0.39). In a multivariable regression model, including patient characteristics and types of surgery and anaesthesia, night-time surgery was independently associated with a higher incidence of intraoperative AEs (odds ratio: 1.44; 95% confidence interval: 1.09-1.90; P = 0.01), but not with a higher incidence of PPCs (odds ratio: 1.32; 95% confidence interval: 0.89-1.90; P = 0.15).
Conclusions: Intraoperative adverse events and postoperative pulmonary complications occurred more often in patients undergoing night-time surgery. Imbalances in patients' clinical characteristics, types of surgery, and intraoperative management at night-time partially explained the higher incidence of postoperative pulmonary complications, but not the higher incidence of adverse events
Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: Post-hoc analysis of LAS VEGAS study
- Author
- Abdel-Razek Ahmed
- Abdelhady Mahdy
- Abdelwahab Hisham Hosny
- Ahmed Ahmed Gouda
- Akgun Fatma Nur
- Algarsamy Shivarajan
- Almagro Angela
- Alvares-Santullano Cesar Aldecoa
- Amaral Joana
- Andersson Elisabeth
- Andreou Antonis
- Andrew Alyson
- Anipchenko Natalia
- Antholopoulos Georgios
- Appleton Sofia
- Arpino Ines
- Arun Oguzhan
- Aukstakalniene Ruta
- Aun Annika
- Avalos Manuel Vico
- Aydogan Eyup
- Azenic-Venzera Darija
- Babayants Andrey
- Baciarello Marco
- Bacuzzi Alessandro
- Ball Lorenzo
- Barrett Colin
- Barsan Victoria
- Bartolini Vittoria
- Bastin Bea
- Battaglini Denise
- Bell Andrea
- Bengisun Zuleyha Kazak
- Beran Maud
- Beretta Luigi
- Bezzina Maureen
- Binnekade Jan
- Bluth Thomas
- Bluth Thomas
- Boer Christa
- Bona Francesco
- Borg Francis Joseph
- Bos Lieuwe
- Boyd Nicholas
- Boztug Neval
- Brazzi Luca
- Breidablik Alena
- Bressan Filippo
- Brown Lucy
- Brugnoni Elisa
- Brujevic Jan
- Bruncakova Katarina
- Brunelli Andrea
- Brunetti Iole
- Bundy Anette
- Burton Maudrian
- Bystritski Dmitri
- Bytyqi Adem
- Cadilha Susana
- Cain Alistair
- Calton Emily
- Camci Emre
- Campanile Annamaria
- Canet Jaume
- Canet Jaume
- Canli Seyda
- Carev Mladen
- Carvalho Peter
- Castellani Gianluca
- Cerati Giorgia
- Chikungwa Moses
- Chishti Ahmed
- Cindea Iulia
- Cinnella Gilda
- Clements Deborah
- Colley Julie
- Copotoiu Ruxandra
- Copotoiu Sanda-Maria
- Corneci Dan
- Correia Mariana
- Cortegiani Andrea
- Coskunfirat Nesil
- Costea Dan
- Creagh-Brown Ben
- Creary Thais
- D'Antini Davide
- Damster Sandrine
- Das Ashok
- Datson Amanda
- Davies Simon
- de Abajo Larriba Ana
- de Abreu Marcel Gama
- de Andrés Ibañez Jose Antonio
- de Baerdemaeker Luc
- de Bruyne Ann
- de Hert Stefan
- de Jong Jasper
- de Lurdes Goncalves Castro Maria
- de Michele Michele
- Deane Jill
- Defez Mario
- Delunas Luigi
- Dennesen Paul
- di Parma Ambra Licia
- Djonoviċ-Omanoviċ Dejana
- Donovan Andrew
- Dossi Roberto
- Drab Michal
- Droc Gabriela
- Dropulic Natasa
- Dudas Radovan
- Dutu Madalina
- Duvekot Anne
- Dvorscak Matea Bogdanovic
- Dylst Dimitri
- Dzurnakova Paula
- Eden Arieh
- el Kafrawy Samir
- el-Shaarawy Ahmed Mostafa
- Ellison Branwen
- Erceg Gorjana
- Everett Lynn
- Fava Josep
- Fedorov Sergei
- Fernandez-Bustamante Ana
- Fernando Luiz
- Ferrando Carlos
- Ferreira Daniel
- Filipescu Daniela
- Filipsky Radek
- Fjellanger Frode
- Florou Panagiota
- Foot Jayne
- Forget Patrice
- Fota Ruxandra
- Fouracres Anna
- Franklin Danielle
- Frkovic Vedran
- Fuller Debbie
- Futier Emmanuel
- Gama de Abreu Marcelo
- Garotescu Ioana Popescu
- Gavranovic Zeljka
- Gecaj-Gashi Agreta
- Geib Johann
- Generali Michela
- Gerard Adeline
- Gherghina Iorel
- Giacoletto Gianmarco
- Giancarlo Luigi
- Giarratano Antonino
- Gibb Sarah
- Gillberg Lars
- Gkiokas Georgios
- Gombotz Hans
- Goodall Cait
- Goranovic Tanja
- Gottschalk Andre
- Granell Manuel
- Grasso Salvatore
- Gratarola Angelo
- Grintescu Ioana Cristina
- Grintescu Ioana Marina
- Gritsan Alexey
- Gritsan Galina
- Grosu Irina
- Grynyuk Andriy
- Gueldner Andreas
- Gunenc Ferim
- Guran Catalin-Traian
- Hadimioglu Necmiye
- Harazim Hana
- Hasan Wael Fathy
- Hemmes Sabrine
- Hemmes Sabrine N. T.
- Hering Jens
- Herodes Eiko
- Heyse Bjorn
- Hiesmayr Michael
- Hiesmayr Michael
- Higham Charley
- Hodt Katharina Skirstad
- Hollmann M. Wiersma
- Hollmann Markus
- Homan Elizabeth
- Horhota Lucian
- Hudacek Kamil
- in 't Veld Bas
- Ivars Stefan
- Ivic Dubravka
- Jaber Samir
- Jaber Samir
- Jackson Clare
- Jacobs Tom
- Jammer Ib
- Jawad Monir
- Jirmanova Katerina
- Jones Stephanie
- Jovanov Miroljub
- Jurate Sipylaite
- Juricic Kazimir
- Juros-Zovko Marina
- Kahn David
- Kapkan Tatyana
- Karaman Fatma Mine
- Karanovic Nenad
- Karapanos Dimitris
- Karbonskiene Aurika
- Karjagin Juri
- Kazbek Baturay Kansu
- Kienbaum Peter
- Kiss Thomas
- Kivik Peeter
- Koch Thea
- Kodaganallur Krishnan
- Kolacek Tomas
- Komissarova Irina
- Konrad Mirja
- Kontrimaviciute Egle
- Kopic Jasminka
- Kor Daryl
- Korolkov Oleg
- Kosinova Martina
- Kostadinov Ivan
- Krassler Jens
- Kroell Wolfgang
- Kucukgoncu Semra
- Kucukguclu Semih
- Kulikov Alexander
- Kusnierikova Zuzana
- Kusre Sandeep
- Kuvaki Bahar
- Kvolik Slavica
- la Bella Daniela
- Landoni Giovanni
- Lazukic Aleksandra
- Leva Brigitte
- Leykin Yigal
- Likhvantsev Valery
- Limb James
- Liperi Corrado
- Lisi Alberto
- Liskova Katarina
- Lois Fernande
- Lubnin Andrey
- Lugovoy Alexander
- Lundberg Michael
- Luzier Elizabeth
- Mackenzie Felicity
- Magdy Mohamed
- Mahran Mohamed
- Maldini Branka
- Mall Merilin
- Maral Jale
- Markovic-Bozic Jasmina
- Marrella Antonella
- Marret Emmanuel
- Marri Sudhakar
- Martinez Francisco Hidalgo
- Martinez Raquel
- Martins Diogo
- Mazul-Sunko Branka
- Mazur Andriy
- Mellin-Olsen Jannicke
- Melo Marcos Vidal
- Mercer Pauline
- Merzky Simone
- Metwally Tarek
- Metzler Helfried
- Mihajlovic Dunja
- Miliauskas Povilas
- Mills Gary
- Mills Gary H.
- Minto Gary
- Mirabella Lucia
- Mirea Liliana
- Mirkovic Ivan
- Miskovic Petar
- Mladic-Batinica Inga
- Mohr Otto
- Moise Alida
- Moldovan Septimiu Gheorghe
- Molin Alexandre
- Molina Ruby
- Momeni Mona
- Monedero Pablo
- Montagnani Luca
- Montalto Francesca
- Monteirosa Angela
- Montgomery Jane
- Morais Erick
- Moral Victoria
- Morelli Paola
- Moret Enrique
- Moreton Sarah
- Mowat Stephen
- Muhardri Dalip
- Musella Giuseppe
- Nadolski Maria
- Negoita Silvius
- Nestler Christian
- Nouris Christos
- Novak-Jankovic Vesna
- Novak-Supe Barbka
- Nunez M. nica Rodriguez
- Nutt Helen
- Oganjan Juri
- Oputric Ivana
- Ovezov Alexey
- Ozbilgin Şule
- Ozgen Serpil Ustalar
- Paddle Jonathan
- Palmer Janet
- Pandazi Aggeliki
- Pannen Benedikt
- Parente Suzana
- Pasin Laura
- Pastor Ernesto
- Pavicic Anna Marija
- Pearse Rupert
- Pejakovic Jasmina
- Pekle-Golez Ana
- Pellerano Giulia
- Pelosi Paolo
- Pelosi Paolo
- Peradze Sopio
- Perez Gisela
- Perez Rocio
- Pernar Selma
- Pesce Caterina Valeria
- Petcu Ana Maria
- Petit Antoine
- Pezzatto Stefano
- Pistidda Laura
- Pizov Reuven
- Plichon Benoit
- Poelaert Jan
- Polakovicova Lenka
- Popescu Mihai
- Portch David
- Pospiech Audrey
- Pourzitaki Chryssa
- Prades Albert
- Prodan Alexandru Bogdan
- Prokoshev Pavel
- Puigbo Carlos
- Pulletz Mark
- Putensen Christian
- Radocaj Tomislav
- Rafi Amir
- Ragazzi Riccardo
- Raimondo Pasquale
- Raineri Santi Maurizio
- Raj Ashok
- Rambhatla Mrutyunjaya
- Rapido Francesca
- Raymode Parizade
- Reske Andreas
- Ricardo Ana
- Riciu Magda
- Rico Jesus
- Robba Chiara
- Roberts Helen
- Rodenas Frederic
- Rodrigues Sara
- Roels Nathalie
- Rogers Elaine
- Rogerson David
- Rose Alastair
- Rousseau Guy
- Rucklidge Matthew
- Ruiz Cristina Saiz
- Russotto Vincenzo
- Sada Fatos
- Saeed Yousif
- Salciute Erika
- Sales Gabriele
- Saltali Ali
- Sances Daniele
- Sanli Suat
- Sanlikarip Ceren
- Sarapuu Kaili
- Sardo Elena
- Saric Jadranka Pavicic
- Sassone Marta Eugenia
- Scavonetto Federica
- Schaefer Maximilian
- Scharffenberg Martin
- Schmid Werner
- Schmid Werner
- Scholes Helen
- Schultz Marcus
- Schultz Marcus J.
- Schwerdtfeger Ben
- Sehovic Mirna
- Selvi Onur
- Sendra Mar
- Senturk Nuzhet Mert
- Senturk Ozgur
- Serpa Neto Ary
- Servillo Giuseppe
- Severgnini Paolo
- Severgnini Paolo
- Severijns Charlotte
- Shafi-Kabiri Amir
- Shelley Ben
- Sher Sara
- Sidiropoulou Tatiana
- Sileo Rosanna
- Simeson Karen
- Simon Antonio Martínez
- Simon Philipp
- Sivrikoz Nukhet
- Skiljic Sonja
- Smekalova Olga
- Smith Thomas
- Sobona Villiam
- Solca Maurizio
- Solier Marc
- Sormus Alar
- Soro Marina
- Sottosanti Vicari
- Spadaro Savino
- Spano Gianluca
- Spieth Peter
- Spindler-Vesel Alenka
- Sprung Juraj
- Stancombe Lucia
- Stourac Petr
- Strazisar Branka
- Stroumpoulis Konstantinos
- Struber Gerd
- Sulemanji Demet
- Sungur Zerrin
- Susarla Jaysimha
- Szewczyk Margaret
- Tareco Glória
- Tarzia Valentina
- Tasoulis Marios-Konstantinos
- Teberaite Zivile
- Temino Maria Jose Yepes
- Theodoraki Kassiani
- Thiem Denny Tran
- Tikuisis Renatas
- Tolcser Zsolt
- Tomescu Dana
- Tomkute Gabija
- Tommasino Concezione
- Toraman Fevzi
- Tredici Stefano
- Treschan Tanja
- Tsaousi Georgia
- Tudoroiu Marian Irinel
- Tze Yeo
- Uhlig Christopher
- Unzueta Mari Carmen
- Urbanek Bernhard
- Valsamidis Dimitrios
- van Beek Rienk
- van de Velde Stijn
- van Limmen Jurgen
- van Malderen Marie-Claire
- van Melkebeek Jeroen
- van Mossevelde Veerle
- Vargas Maria
- Varma Sandeep
- Venkatesh Suresh
- Venturino Marco
- Veres Mihaly
- Verri Marco
- Vidal Melo Marcos F.
- Vinkovic Hrvoje
- Vitkova Katerina
- Vivo Jose Tatay
- Voje Minca
- Volfova Ivana
- Volta Carlo Alberto
- Vorotyntsev Sergiy
- Walker Rachel
- Watt Philip
- Wayman Lisa
- Wegscheider Thomas
- Weingarten Toby
- Weiss Martin
- Welch Leanne
- Werger Alice
- West Claire
- Westerheide Diana
- Wiersma Irene
- Williams John
- Wrigge Hermann
- Wrigge Hermann
- Wutai Stanley
- Wyffels Piet
- Xuereb John
- Yassin Hany
- Yates Susan
- Yildiz Mine
- Yilmaz Murat
- Zafeiropoulou Foteini
- Zalina Karginova
- Zamidei Lucia
- Zangrillo Alberto
- Zelinkova Maria
- Zilic Antonio
- Zoppellari Roberto
- Zuleika Maka
- Zunic Josip
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 02/04/2020
- Field of study
Background: Limited information is available regarding intraoperative ventilator settings and the incidence of postoperative pulmonary complications (PPCs) in patients undergoing neurosurgical procedures. The aim of this post-hoc analysis of the 'Multicentre Local ASsessment of VEntilatory management during General Anaesthesia for Surgery' (LAS VEGAS) study was to examine the ventilator settings of patients undergoing neurosurgical procedures, and to explore the association between perioperative variables and the development of PPCs in neurosurgical patients. Methods: Post-hoc analysis of LAS VEGAS study, restricted to patients undergoing neurosurgery. Patients were stratified into groups based on the type of surgery (brain and spine), the occurrence of PPCs and the assess respiratory risk in surgical patients in Catalonia (ARISCAT) score risk for PPCs. Results: Seven hundred eighty-four patients were included in the analysis; 408 patients (52%) underwent spine surgery and 376 patients (48%) brain surgery. Median tidal volume (VT) was 8 ml [Interquartile Range, IQR = 7.3-9] per predicted body weight; median positive end-expiratory pressure (PEEP) was 5 [3 to 5] cmH20. Planned recruitment manoeuvres were used in the 6.9% of patients. No differences in ventilator settings were found among the sub-groups. PPCs occurred in 81 patients (10.3%). Duration of anaesthesia (odds ratio, 1.295 [95% confidence interval 1.067 to 1.572]; p = 0.009) and higher age for the brain group (odds ratio, 0.000 [0.000 to 0.189]; p = 0.031), but not intraoperative ventilator settings were independently associated with development of PPCs. Conclusions: Neurosurgical patients are ventilated with low VT and low PEEP, while recruitment manoeuvres are seldom applied. Intraoperative ventilator settings are not associated with PPCs
Association between night-time surgery and occurrence of intraoperative adverse events and postoperative pulmonary complications
- Author
- Abdel-Razek Ahmed
- Abdelhady Mahdy
- Abdelwahab Hisham Hosny
- Ahmed Ahmed Gouda
- Akgun Fatma Nur
- Aldecoa Alvares-Santullano Cesar
- Algarsamy Shivarajan
- Almagro Angela
- Amaral Joana
- Andersson Elisabeth
- Andreou Antonis
- Andrew Alyson
- Anipchenko Natalia
- Antholopoulos Georgios
- Appleton Sofia
- Arpino Ines
- Arun Oguzhan
- Aukstakalniene Ruta
- Aun Annika
- Avalos Manuel Vico
- Aydogan Eyup
- Azenic-Venzera Darija
- Babayants Andrey
- Baciarello Marco
- Bacuzzi Alessandro
- Ball L.
- Barrett Colin
- Barsan Victoria
- Bartolini Vittoria
- Bastin Bea
- Bell Andrea
- Bengisun Zuleyha Kazak
- Beran Maud
- Beretta Luigi
- Bezzina Maureen
- Binnekade Jan
- Bluth Thomas
- Boer Christa
- Bona Francesco
- Borg Francis Joseph
- Bos Lieuwe
- Boyd Nicholas
- Boztug Neval
- Brazzi Luca
- Breidablik Alena
- Bressan Filippo
- Brown Lucy
- Brugnoni Elisa
- Brujevic Jan
- Bruncakova Katarina
- Brunelli Andrea
- Brunetti Iole
- Bundy Anette
- Burton Maudrian
- Bystritski Dmitri
- Bytyqi Adem
- Cadilha Susana
- Cain Alistair
- Calton Emily
- Camci Emre
- Campanile Annamaria
- Canet J.
- Canli Seyda
- Carev Mladen
- Carmen Unzueta Mari
- Carvalho Peter
- Castellani Gianluca
- Cerati Giorgia
- Chikungwa Moses
- Chishti Ahmed
- Cindea Iulia
- Cinnella Gilda
- Clements Deborah
- Colley Julie
- Copotoiu Ruxandra
- Copotoiu Sanda-Maria
- Corneci Dan
- Correia Mariana
- Cortegiani A.
- Coskunfirat Nesil
- Costea Dan
- Creagh-Brown Ben
- Creary Thais
- D'antini Davide
- Damster Sandrine
- Das Ashok
- Datson Amanda
- Davies Simon
- de Abajo Larriba Ana
- de Abreu M. Gama
- de Andres Ibanez Jose Antonio
- De Baerdemaeker Luc
- De Bruyne Ann
- de Hert Stefan
- De Jong Jasper
- De Michele Michele
- Deane Jill
- Defez Mario
- Delunas Luigi
- Dennesen Paul
- Di Parma Ambra Licia
- Djonovic-Omanovic Dejana
- Donovan Andrew
- Dossi Roberto
- Drab Michal
- Droc Gabriela
- Dropulic Natasa
- Dudas Radovan
- Dutu Madalina
- Duvekot Anne
- Dvorscak Matea Bogdanovic
- Dylst Dimitri
- Dzurnakova Paula
- Eden Arieh
- el Kafrawy Samir
- El-Shaarawy Ahmed Mostafa
- Ellison Branwen
- Erceg Gorjana
- Everett Lynn
- Fava Josep
- Fedorov Sergei
- Fernandez-Bustamante Ana
- Fernando Luiz
- Ferrando Carlos
- Ferreira Daniel
- Filipescu Daniela
- Filipsky Radek
- Fjellanger Frode
- Florou Panagiota
- Foot Jayne
- Forget Patrice
- Fota Ruxandra
- Fouracres Anna
- Franklin Danielle
- Frkovic Vedran
- Fuller Debbie
- Futier Emmanuel
- Garotescu Ioana Popescu
- Gavranovic Zeljka
- Gecaj-Gashi Agreta
- Geib Johann
- Generali Michela
- Gerard Adeline
- Gherghina Iorel
- Giacoletto Gianmarco
- Giarratano Antonino
- Gibb Sarah
- Gillberg Lars
- Gkiokas Georgios
- Gombotz Hans
- Goncalves Castro Maria de Lurdes
- Goodall Cait
- Goranovic Tanja
- Gottschalk Andre
- Granell Manuel
- Grasso Salvatore
- Gratarola Angelo
- Gregoretti C.
- Grintescu Ioana Cristina
- Grintescu Ioana Marina
- Gritsan Alexey
- Gritsan Galina
- Grosu Irina
- Grynyuk Andriy
- Gueldner Andreas
- Gunenc Ferim
- Guran Catalin-Traian
- Hadimioglu Necmiye
- Harazim Hana
- Hasan Wael Fathy
- Hemmes S. N. T.
- Hemmes Sabrine
- Hering Jens
- Herodes Eiko
- Heyse Bjorn
- Hidalgo Martinez Francisco
- Hiesmayr M.
- Hiesmayr Michael
- Higham Charley
- Hodt Katharina Skirstad
- Hollmann M. W.
- Hollmann Markus
- Homan Elizabeth
- Horhota Lucian
- Hudacek Kamil
- in 't Veld Bas
- Ivars Stefan
- Ivic Dubravka
- Jaber Samir
- Jackson Clare
- Jacobs Tom
- Jammer Ib
- Jawad Monir
- Jirmanova Katerina
- Jones Stephanie
- Jovanov Miroljub
- Jurate Sipylaite
- Juricic Kazimir
- Juros-Zovko Marina
- Kahn David
- Kapkan Tatyana
- Karaman Fatma Mine
- Karanovic Nenad
- Karapanos Dimitris
- Karbonskiene Aurika
- Karjagin Juri
- Kazbek Baturay Kansu
- Kienbaum Peter
- Kiss Thomas
- Kivik Peeter
- Koch Thea
- Kodaganallur Krishnan
- Kolacek Tomas
- Komissarova Irina
- Konrad Mirja
- Kontrimaviciute Egle
- Kopic Jasminka
- Kor Daryl
- Korolkov Oleg
- Kosinova Martina
- Kostadinov Ivan
- Krassler Jens
- Kroell Wolfgang
- Kucukgoncu Semra
- Kucukguclu Semih
- Kulikov Alexander
- Kusnierikova Zuzana
- Kusre Sandeep
- Kuvaki Bahar
- Kvolik Slavica
- La Bella Daniela
- Landoni Giovanni
- Lazukic Aleksandra
- Leva Brigitte
- Leykin Yigal
- Likhvantsev Valery
- Limb James
- Liperi Corrado
- Lisi Alberto
- Liskova Katarina
- Lois Fernande
- Lubnin Andrey
- Lugovoy Alexander
- Lundberg Michael
- Luzier Elizabeth
- Mackenzie Felicity
- Magdy Mohamed
- Mahran Mohamed
- Maldini Branka
- Mall Merilin
- Maral Jale
- Markovic-Bozic Jasmina
- Marrella Antonella
- Marret Emmanuel
- Marri Sudhakar
- Martinez Simon Antonio
- Martinez Raquel
- Martins Diogo
- Mazul-Sunko Branka
- Mazur Andriy
- Mellin-Olsen Jannicke
- Melo M. F. V.
- Melo Marcos Vidal
- Mercer Pauline
- Merzky Simone
- Metwally Tarek
- Metzler Helfried
- Mihajlovic Dunja
- Miliauskas Povilas
- Mills G. H.
- Mills Gary
- Minto Gary
- Mirabella Lucia
- Mirea Liliana
- Mirkovic Ivan
- Miskovic Petar
- Mladic-Batinica Inga
- Mohr Otto
- Moise Alida
- Moldovan Septimiu Gheorghe
- Molin Alexandre
- Molina Ruby
- Momeni Mona
- Monedero Pablo
- Montagnani Luca
- Montalto Francesca
- Monteirosa Angela
- Montgomery Jane
- Morais Erick
- Moral Victoria
- Morelli Paola
- Moret Enrique
- Moreton Sarah
- Mowat Stephen
- Muhardri Dalip
- Musella Giuseppe
- Nadolski Maria
- Negoita Silvius
- Nestler Christian
- Neto A. S.
- Nouris Christos
- Novak-Jankovic Vesna
- Novak-Supe Barbka
- Nutt Helen
- Oganjan Juri
- Oputric Ivana
- Ovezov Alexey
- Ozbilgin Sule
- Ozgen Serpil Ustalar
- Paddle Jonathan
- Palmer Janet
- Pandazi Aggeliki
- Pannen Benedikt
- Parente Suzana
- Pasin Laura
- Pastor Ernesto
- Pavicic Anna Marija
- Pearse Rupert
- Pejakovic Jasmina
- Pekle-Golez Ana
- Pellerano Giulia
- Pelosi P.
- Peradze Sopio
- Perez Gisela
- Perez Rocio
- Pernar Selma
- Pesce Caterina Valeria
- Petcu Ana Maria
- Petit Antoine
- Pezzatto Stefano
- Pistidda Laura
- Pizov Reuven
- Plichon Benoit
- Poelaert Jan
- Polakovicova Lenka
- Popescu Mihai
- Portch David
- Pospiech Audrey
- Pourzitaki Chryssa
- Prades Albert
- Prodan Alexandru Bogdan
- Prokoshev Pavel
- Puigbo Carlos
- Pulletz Mark
- Putensen C.
- Radocaj Tomislav
- Rafi Amir
- Ragazzi Riccardo
- Raimondo Pasquale
- Raineri Santi Maurizio
- Raj Ashok
- Rambhatla Mrutyunjaya
- Rapido Francesca
- Raymode Parizade
- Reske Andreas
- Ricardo Ana
- Riciu Magda
- Rico Jesus
- Roberts Helen
- Rodenas Frederic
- Rodrigues Sara
- Rodriguez Nunez Monica
- Roels Nathalie
- Rogers Elaine
- Rogerson David
- Rose Alastair
- Rousseau Guy
- Rucklidge Matthew
- Russotto Vincenzo
- Sada Fatos
- Saeed Yousif
- Saiz Ruiz Cristina
- Salciute Erika
- Sales Gabriele
- Saltali Ali
- Sances Daniele
- Sanli Suat
- Sanlikarip Ceren
- Sarapuu Kaili
- Sardo Elena
- Saric Jadranka Pavicic
- Sassone Marta Eugenia
- Scavonetto Federica
- Schaefer Maximilian
- Scharffenberg Martin
- Schmid W.
- Schmid Werner
- Scholes Helen
- Schultz M. J.
- Schultz Marcus
- Schwerdtfeger Ben
- Sehovic Mirna
- Selvi Onur
- Sendra Mar
- Senturk Nüzhet Mert
- Senturk Ozgur
- Servillo Giuseppe
- Severgnini P.
- Severgnini Paolo
- Severijns Charlotte
- Shafi-Kabiri Amir
- Shelley Ben
- Sher Sara
- Sidiropoulou Tatiana
- Sileo Rosanna
- Simeson Karen
- Simon Philipp
- Sivrikoz Nukhet
- Skiljic Sonja
- Smekalova Olga
- Smith Thomas
- Sobona Villiam
- Solca Maurizio
- Solier Marc
- Sormus Alar
- Soro Marina
- Sottosanti Luigi Giancarlo Vicari
- Spadaro Savino
- Spano Gianluca
- Spieth Peter
- Spindler-Vesel Alenka
- Sprung Juraj
- Stancombe Lucia
- Stourac Petr
- Strazisar Branka
- Stroumpoulis Konstantinos
- Struber Gerd
- Sulemanji Demet
- Sungur Zerrin
- Susarla Jaysimha
- Szewczyk Margaret
- Tareco Gloria
- Tarzia Valentina
- Tasoulis Marios-Konstantinos
- Tatay Vivo Jose
- Teberaite Zivile
- Theodorak Kassiani
- Thiem Denny Tran
- Tikuisis Renatas
- Tolcser Zsolt
- Tomescu Dana
- Tomkute Gabija
- Tommasino Concezione
- Toraman Fevzi
- Tredici Stefano
- Treschan Tanja
- Tsaousi Georgia
- Tudoroiu Marian Irinel
- Tze Yeo
- Uhlig Christopher
- Urbanek Bernhard
- Valsamidis Dimitrios
- van Beek Rienk
- van de Velde Stijn
- Van Limmen Jurgen
- van Malderen Marie-Claire
- van Melkebeek Jeroen
- van Mossevelde Veerle
- Vargas Maria
- Varma Sandeep
- Venkatesh Suresh
- Venturino Marco
- Veres Mihaly
- Verri Marco
- Vinkovic Hrvoje
- Vitkova Katerina
- Voje Minca
- Volfova Ivana
- Volta Carlo Alberto
- Vorotyntsev Sergiy
- Walker Rachel
- Watt Philip
- Wayman Lisa
- Wegscheider Thomas
- Weingarten Toby
- Weiss Martin
- Welch Leanne
- Werger Alice
- West Claire
- Westerheide Diana
- Wiersma Irene
- Williams John
- Wrigge H.
- Wrigge Hermann
- Wutai Stanley
- Wyffels Piet
- Xuereb John
- Yassin Hany
- Yates Susan
- Yepes Temino Maria Jose
- Yildiz Mine
- Yilmaz Murat
- Zafeiropoulou Foteini
- Zalina Karginova
- Zamidei Lucia
- Zangrillo Alberto
- Zelinkova Maria
- Zilic Antonio
- Zoppellari Roberto
- Zuleika Maka
- Zunic Josip
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background: The aim of this post hoc analysis of a large cohort study was to evaluate the association between night-time surgery and the occurrence of intraoperative adverse events (AEs) and postoperative pulmonary complications (PPCs)
Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study
- Author
- Abad Gurumeta Alfredo
- Abernethy Caroline
- Abigail Patrick
- Achaibar Kira
- Adam Emily
- Afshari Arash
- Agudelo Montoya María Elizabeth
- Akgün Fatma Nur
- Aletti Gabriele
- Alkış Neslihan
- Allan Ashley
- Allan Katie
- Allaouchiche Bernard
- Allcock Clare
- Almasy Emoke
- Amey Isobel
- Amigoni Maria
- Andersen Elin
- Andersson Peder
- Anipchenko Natalya
- Antunes Pedro
- Armstrong Earlene
- Aslam Tayyba
- Assunção José-Pedro
- Ausserer Julia
- Avvai Mary
- Awad Nahla
- Ayas Montero Begoña
- Ayuso Mercedes
- Azevedo Patricia
- Badarau Victoria
- Badescu Roxana
- Baiardo Redaelli Martina
- Baird Colin
- Baird Yolanda
- Baker Tim
- Balaji Packianathaswamy
- Balan Cristina
- Balandin Alina
- Balescu-Arion Carmen
- Baliuliene Vilda
- Baltasar Isabel Jorge
- Baluch Saif Nasr
- Bandrabur Daniela
- Bankewitz Carla
- Barber Katrina
- Barbera Francesco
- Barcraft-Barnes Helena
- Barletti Valentina
- Barnett Gill
- Baron Kirsty
- Barros Ana
- Barsan Victoria
- Bartlett Pauline
- Batistaki Chrysanthi
- Baumgarten Georg
- Baumüller Eva
- Baytaş Volkan
- Beauchamp Nigel
- Becerra Cayetano Isabel A.
- Bell Stephanie
- Bellandi Mattia
- Belletti Alessandro
- Belmonte Cuenca Julio
- Benitez-Cano Adela
- Beretta Luigi
- Berger Marc Moritz
- Bergmann Nicole
- Bergmark Kristina
- Bermudez Lopez Maria
- Bernotaite Monika
- Beurskens Charlotte
- Bidd Heena
- Bifulco Francesca
- Bignami Elena
- Bilic Aleksandar
- Bilskiene Diana
- Bischoff Petra
- Bishop Luke
- Bjønness Therese
- Blaylock Heather
- Blethyn Kate
- Blincoe Thomas
- Blobner Manfred
- Blobner Manfred
- Blobner Manfred
- Blokhin Ivan
- Blunt Nadia
- Boer Christa
- Bois Grégory
- Bonicolini Eleonora
- Booth Joanna
- Borecka-Kedzierska Miraslawa
- Borstnar Katarina
- Borys Michal
- Boselli Emmanuel
- Bouvet Lionel
- Bouwman Arthur
- Bowen Leonora
- Bowrey Sarah
- Boxall Leigh
- Bozić Teodora
- Bradley Tom
- Branco Teresa
- Brazzi Luca
- Brazzoni Marcella
- Brear Tracy
- Brogly Nicolas
- Brohi Farooq
- Broms Jacob
- Bubliauskas Andrius
- Bucolo Gea Erika
- Buerkle Hartmut
- Buggy Donal
- Buhre Wolfgang F.
- Bukauskas Tomas
- Butturini Francesco
- Byttner Anders
- Cabrera Díaz Itahísa
- Calderon Adriana
- Calhau Ricardo
- Callejo Angel
- Cammu Guy
- Campesato Manuela
- Camsooksai Julie
- Can Özlem Selvi
- Cantor Andreea
- Carise Elsa
- Carmona Cristina
- Carreteiro Joana
- Carrieri Cosima
- Carter Anna
- Casal Manuela
- Casanova Irene
- Cascella Marco
- Casero Luis M.
- Casiraghi Giuseppina Maria
- Castelo-Branco Laila
- Castro Arranz Carlos
- Cernea Daniela
- Cervantes Oriol
- Chandler Ben
- Charnock Robert
- Chatzimicali Aikaterini
- Chervjakov Igor
- Chinery Elaine
- Chishti Ahmad
- Chondhury Priyakam
- Christie Emily
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- Unterbuchner Christoph
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- v Tiesenhausen Anna
- Vaida Simona
- Valldeperas Ferrer Silvia
- Valldeperas Hernandez Maria Inmaculada
- Valsamidis Dimitrios
- Van Beek Rienk
- van Dasselaar Nick
- van der Beek Tim
- Van Duivenvoorde Yoni
- van Klei Wilton A.
- Van Poorten Frans
- Van Zaane Bas
- Van Zundert Tom
- van Zyl Rebekka
- Vargas Munoz Ana Milena
- Varsani Nimu
- Vasconcelos Pedro
- Vassilakis George
- Vecchiatini Tommaso
- Vercauteren Marcel
- Verdouw Bas
- Verheyen Veerle
- Verri Marco
- Večeřa Lubomir
- Vicari Sottosanti Luigi Giancarlo
- Vico Manuel
- Vidal Mitjans Patricia
- Vilardi Anna
- Vissicchio Daniela
- Vitale Giovanni
- Vitković Bibiana
- Vizcaychipi Marcela Paola
- Voicu Alexandra
- Voje Minca
- Volfová Ivana
- Volta Carlo Alberto
- Von Lutterotti Theresia
- Vrecič-Slabe Simona
- Vukcevic Dejan
- Vukovic Rade
- Vullo P. Agostina
- Wade Andrew
- Wallberg Hanna
- Wallden Jakob
- Wallner Johann
- Walther Sturesson Louise
- Watson Davina
- Weber Stefan
- Wegiel Leskiewicz Anna
- Weller Debbie
- Wensing Carin
- Werkmann Markus
- Westberg Henrik
- Wikström Erik
- Willett Emma
- Williams Benedict
- Wilson Robin
- Wirth Steffen
- Wittmann Maria
- Wood Laura
- Wright Stella
- Zachoval Christian
- Zambon Massimo
- Zampieri Silvia
- Zampone Salvatore
- Zangrillo Alberto
- Zani Gianluca
- Zavackiene Asta
- Ziegleder Raphael
- Zonneveldt Harry
- Zsisku Lajos
- Zucker Tom-Philipp
- Zuleika Mehrun
- Zupančič Darja
- Åslin Bjorn
- Şanli Karip Ceren
- Štourač Petr
- Żukowski Maciej
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2019
- Field of study
Background Results from retrospective studies suggest that use of neuromuscular blocking agents during general
anaesthesia might be linked to postoperative pulmonary complications. We therefore aimed to assess whether the use
of neuromuscular blocking agents is associated with postoperative pulmonary complications.
Methods We did a multicentre, prospective observational cohort study. Patients were recruited from 211 hospitals in
28 European countries. We included patients (aged ≥18 years) who received general anaesthesia for any in-hospital
procedure except cardiac surgery. Patient characteristics, surgical and anaesthetic details, and chart review at discharge
were prospectively collected over 2 weeks. Additionally, each patient underwent postoperative physical examination
within 3 days of surgery to check for adverse pulmonary events. The study outcome was the incidence of postoperative
pulmonary complications from the end of surgery up to postoperative day 28. Logistic regression analyses were
adjusted for surgical factors and patients’ preoperative physical status, providing adjusted odds ratios (ORadj) and
adjusted absolute risk reduction (ARRadj). This study is registered with ClinicalTrials.gov, number NCT01865513.
Findings Between June 16, 2014, and April 29, 2015, data from 22803 patients were collected. The use of neuromuscular
blocking agents was associated with an increased incidence of postoperative pulmonary complications in patients who
had undergone general anaesthesia (1658 [7·6%] of 21694); ORadj 1·86, 95% CI 1·53–2·26; ARRadj –4·4%, 95% CI
–5·5 to –3·2). Only 2·3% of high-risk surgical patients and those with adverse respiratory profiles were anaesthetised
without neuromuscular blocking agents. The use of neuromuscular monitoring (ORadj 1·31, 95% CI 1·15–1·49;
ARRadj –2·6%, 95% CI –3·9 to –1·4) and the administration of reversal agents (1·23, 1·07–1·41; –1·9%, –3·2 to –0·7)
were not associated with a decreased risk of postoperative pulmonary complications. Neither the choice of sugammadex
instead of neostigmine for reversal (ORadj 1·03, 95% CI 0·85–1·25; ARRadj –0·3%, 95% CI –2·4 to 1·5) nor extubation at
a train-of-four ratio of 0·9 or more (1·03, 0·82–1·31; –0·4%, –3·5 to 2·2) was associated with better pulmonary outcomes.
Interpretation We showed that the use of neuromuscular blocking drugs in general anaesthesia is associated with an
increased risk of postoperative pulmonary complications. Anaesthetists must balance the potential benefits of
neuromuscular blockade against the increased risk of postoperative pulmonary complications
Prospective observational cohort study on grading the severity of postoperative complications in global surgery research
- Author
- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Aflori Laura
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Amri Khalid
- Al Hussaini Sabah
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alias Raja Liza Raja
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
- Amstrup-Hansen Louise
- Anagnou Athina
- Andersen Cheme
- Anderson Charlotte
- Anderson Colette
- Anderson Frank
- Anderson Philip
- Andreadaki Evangelia
- Andreou Alexandros
- Andreou Prematie
- Andrew Alyson
- Andrews Emma
- Angel Miguel Paludi
- Angermair Stefan
- Angus Kirsty
- Anillo Victor
- Anizi Mashel Al
- Antal Oana
- Antill Philip
- Antoniadou Eleni
- Apagaki Eymorfia
- Apostolou Konstantinos
- Applewhaite Christopher
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Araujo Daniela Marques
- Arawwawala Dilshan
- Ardern Diane
- Argue Ruth
- Aribawa Mahaalit Alit
- Arkalaki Eleni
- Armaganidis Apostolos
- Armstrong John
- Armstrong Richard
- Arnaoutoglou Christina
- Arnaoutoglou Elena
- Arnold Glenn
- Arrandale Lindsay
- Arrich James
- Arrigo Mario
- Arshad Homa
- Arshad Mohammed Asif
- Artiles Tania Socorro
- Arumugam Swarna
- Arustei Mirela
- Arvaniti Kostoula
- Arvaniti Kostoula
- Arya Aryabiantara
- Arya Shobhit
- Asimakos Andreas
- Aslam M
- Asudo Felicia
- Athanasakis Elias
- Atiku Mamuda
- Attrill Elizabeth
- Attwood Clare
- Auer Patrick
- Avidan Michael
- Avila Erendira Jocelin Dominguez
- Avis Joanne
- Awad Hadi
- Axioti Elena
- Azam Ummi Azmira Ahmad
- Azambuja Pedro
- Azevedo Caroline
- Aziz Faizal Zuhri
- Baas Peter
- Baghirzada Leyla
- Bai Hui-Ping
- Baillie Shelley
- Baines Duncan
- Baio Thalissa Hermínia
- Bairaktari Aggeliki
- Baker Gerard
- Baker Katie-Anne
- Baker Paul
- Balain Birender
- Balajonda Naraida
- Balanescu Andreea
- Balasubramaniam Madhu
- Baldisserotto Sérgio
- Baldwin Jacqueline
- Baldwin Matthew
- Balfoussia Danai
- Bali Christina
- Bandeira Maria Expedito
- Banerjee Robin
- Bankewitz Carla
- Banner-Goodspeed Valerie
- Bao Qi
- Barcraft-Barnes Helena
- Barneto Lisa
- Barnett Andrew
- Barraclough James
- Barras Jean-Pierre
- Barrett Stephen
- Barrett Wendy Joan
- Basanth Sujith
- Batchelor Nick
- Bateman Brian
- Bates Alexander
- Bates Sarah
- Batista Hugo Dias
- Bauchmuller Kris
- Bauer Marlene
- Baumgarten Georg
- Baxter Linden
- Beaton Ceri
- Beattie Scott
- Beattie Scott
- Beattie Scott
- Beavis Vanessa
- Beavis Vanessa
- Bechan Sudha
- Beer Johan
- Bejia Tarek
- Belciu Ioana
- Belda Margarita Tormo
- Bell Gillian
- Bell Rachel
- Bell Rachel
- Bell Stephanie
- Bellandi Mattia
- Bello Jibril
- Beloeil Helene
- Belskiy Vladislav
- Beltran Anna Valle
- Ben-Menachem Erez
- Benavent Pau
- Benevento Angelo
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- Futier Emmanuel
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- Ganter Michael T
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- Greaves Rosanna
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- Harrichandparsad R
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- Hodgkiss Tracey
- Hodgson Richard E
- Hodzovic Emil
- Hoedt Marielle
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- Zapata Darcy Danitza Mari
- Zbitnew Geoff
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- Zeng Qiuting
- Zettergren Jan
- Zhang Baoling
- Zhang Enman
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- Zhao Bo
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- Zhao Ting
- Zhao Weihong
- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zin Nor Hafizah Mohd
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Zundert Tom
- Zyl Rebekka
- åkring Irene
- Ögren Katrin
- Publication venue
- 'Wiley'
- Publication date
- 22/10/2018
- Field of study
Background
The Clavien–Dindo classification is perhaps the most widely used approach for reporting postoperative complications in clinical trials. This system classifies complication severity by the treatment provided. However, it is unclear whether the Clavien–Dindo system can be used internationally in studies across differing healthcare systems in high- (HICs) and low- and middle-income countries (LMICs).
Methods
This was a secondary analysis of the International Surgical Outcomes Study (ISOS), a prospective observational cohort study of elective surgery in adults. Data collection occurred over a 7-day period. Severity of complications was graded using Clavien–Dindo and the simpler ISOS grading (mild, moderate or severe, based on guided investigator judgement). Severity grading was compared using the intraclass correlation coefficient (ICC). Data are presented as frequencies and ICC values (with 95 per cent c.i.). The analysis was stratified by income status of the country, comparing HICs with LMICs.
Results
A total of 44 814 patients were recruited from 474 hospitals in 27 countries (19 HICs and 8 LMICs). Some 7508 patients (16·8 per cent) experienced at least one postoperative complication, equivalent to 11 664 complications in total. Using the ISOS classification, 5504 of 11 664 complications (47·2 per cent) were graded as mild, 4244 (36·4 per cent) as moderate and 1916 (16·4 per cent) as severe. Using Clavien–Dindo, 6781 of 11 664 complications (58·1 per cent) were graded as I or II, 1740 (14·9 per cent) as III, 2408 (20·6 per cent) as IV and 735 (6·3 per cent) as V. Agreement between classification systems was poor overall (ICC 0·41, 95 per cent c.i. 0·20 to 0·55), and in LMICs (ICC 0·23, 0·05 to 0·38) and HICs (ICC 0·46, 0·25 to 0·59).
Conclusion
Caution is recommended when using a treatment approach to grade complications in global surgery studies, as this may introduce bias unintentionally
The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis
- Author
- Ab Majid Mohd Azuan
- Ab Rahman Ahmad Sufian
- Ab Rahman Rusnah
- Abayasinghe Chamika
- Abbas Muntadhar
- Abbott T. E. F.
- Abbott Tom
- Abd Ghafar Fara Nur Idayu
- Abd Hadi Husni Zaeem
- Abdel Goad Ehab Helmy
- Abdullah Noor Hairiza
- Abdur-Rahman Lukman
- Abeloos Jacques
- Abernethy Caroline
- Abidin Ucu Nurhadiat
- Abrunhosa Alexandra
- Absar Mohammed
- Adam Suwayba
- Adams David
- Adams George
- Adamson Michael
- Adekola Oyebola
- Adelaja Yemi
- Ademola Adeyinka
- Adenekan Anthony
- Adenike Odewabi
- Adeolu Augustine A.
- Adetoye Adedapo
- Adewale Badru
- Adigun Tinuola
- Adolfsson Anne
- Africander Cucu
- Afshari Arash
- Agarwal Vandana
- Agodirin Olayide
- Aguzzoli Crisitiano
- Ahamed khader null
- Ahmad Azam Ummi Azmira
- Ahmad Abdurrahman
- Ahmad Norfaizan
- Ahmad T.
- Ahmad Tahania
- Ahmad Yousra
- Ahmed Ahmed
- Ahmed Jamil
- Ahmed Tahania
- Ai Yanqiu
- Aignatoaie Mariana
- Aimoniotou-Georgiou Eleni
- Akanmu Olanrewaju
- Akerman Nik
- Akinwale Mukaila
- Al Anizi Mashel
- Al hussaini Sabah
- Al'Amri Khalid
- Al-Soudaine Yassr
- Aladin Hafiz
- Alagbe-Briggs Olubusola
- Albaj Safauldeensalem
- Alberto Lisi Zaheer Moolla
- AlbertoVolta Carlo
- Alcock David
- Alcock Liam
- Aldecoa Cesar
- Aleixo Fábia Berganton
- Alexander Hazel
- Alexander Maini
- Alexander-Sefre Farhad
- Alherz Fadhel
- Ali Hani
- Ali Marlynn
- Ali Sarah
- Alias Abdul Hafiz
- Alias Anita
- Alit Mahaalit Aribawa
- Allen Samantha
- Allen Sara Jane
- Allison Joanna
- Alloj Chiara
- Allorto Nikki Leigh
- Allsop Joanne
- Almeida William
- Alonso Eduardo
- Alonso José Ignacio
- Alphonsus Christella
- Alvares Danielle
- Alves Maria Joao
- Amador Juan Carlos Bravo
- Ameer Yusuf
- Amendola Cristina Prata
- Ami Noam
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- Andreou Prematie
- Andrew Alyson
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- Angermair Stefan
- Angus Kirsty
- Anillo Victor
- Antal Oana
- Antill Philip
- Antoniadou Eleni
- Antonina Webombesa
- Apagaki Eymorfia
- Apostolou Konstantinos
- Applewhaite Christopher
- Aquino Laura Patricia González
- Ar Praburaj
- Arawwawala Dilshan
- Ardern Diane
- Argue Ruth
- Arkalaki Eleni
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- Armaganidis Apostolos
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- Arshad Mohammed Asif
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- Arumugam Swarna
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- Biccard Bruce M.
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- Buerkle Christian
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- Builu Pierre Monji
- Buise Marc
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- Cheong Edward
- Cherian Ritchie
- Cherrett Veronica
- Chetty Rubendraj R.
- Chew M. S.
- Chew Michelle
- Chhabra Ashok
- Chicken Dennis-Wayne
- Chilinciuc Ion
- Chin Im Im
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- Chlorou Dimitra
- Choi Hyun-min David
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- Christmas Natasha
- Christodoulidis Gregory
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- Christofaki Maria
- Christoforidis Dimitri
- Chronis Christos
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- Chu Susanna
- Chua Pandora
- Chukkambotla Srikanth
- Chung Chun Kwong Eric
- Cifra Elna
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- Ciobotaru Oana Roxana
- Cirstea Emanuel
- Clark Richard
- Clarkson Aisling
- Clarkson Rachel
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- Claxton Andrew
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- Mazzeffi Michael
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- Phillips Stephen
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- Yagnik Anmol
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- Zaimi Donika
- Zakynthinos Spyros
- Zamudio Diana
- Zangrillo Alberto
- Zapata Darcy Danitza Mari
- Zbitnew Geoff
- Zeidan Lisa
- Zeng Qiuting
- Zerman Luiza
- Zettergren Jan
- Zhang Baoling
- Zhang Enman
- Zhang Hongyan
- Zhang Huaigen
- Zhang Huan
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- Zhang Lina
- Zhang Min
- Zhang Mingxiao
- Zhang Qin
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- Zhang Shihai
- Zhang Weiwei
- Zhang Xiaoguang
- Zhang Xiaolin
- Zhang Xiaoyan
- Zhang Xuekang
- Zhang Yan
- Zhang Yapping
- Zhang Ye
- Zhang Yuan
- Zhao Bing
- Zhao Bo
- Zhao Chong
- Zhao Jiashi
- Zhao Jinning
- Zhao Lei
- Zhao Lili
- Zhao Shuna
- Zhao Ting
- Zhao Weihong
- Zhao Weilu
- Zhao Xiaoying
- Zhen Jungang
- Zheng Kang
- Zheng Lina
- Zheng Tianzhao
- Zhong Yi
- Zhou Ce
- Zhou Dachun
- Zhou Haidong
- Zhou Haiyan
- Zhou Jiali
- Zhou Jialong
- Zhou Jing
- Zhou Xian-jin
- Zhu Xiaomao
- Zhu Xiaoping
- Zhu Yi
- Zhu Zhipeng
- Zhuang Xiuxiu
- Zilis Georgios
- Zingerle Nicolette
- Zingg Urs
- Zoerner Frank
- Zonneveldt Harry
- Zou Xiaohua
- Zoulamoglou Menelaos
- Zsisku Lajos
- Åkring Irene
- Ögren Katrin
- Publication venue
- Health Sciences Research Commons
- Publication date
- 30/10/2017
- Field of study
© 2017 British Journal of Anaesthesia Background: The surgical safety checklist is widely used to improve the quality of perioperative care. However, clinicians continue to debate the clinical effectiveness of this tool. Methods: Prospective analysis of data from the International Surgical Outcomes Study (ISOS), an international observational study of elective in-patient surgery, accompanied by a systematic review and meta-analysis of published literature. The exposure was surgical safety checklist use. The primary outcome was in-hospital mortality and the secondary outcome was postoperative complications. In the ISOS cohort, a multivariable multi-level generalized linear model was used to test associations. To further contextualise these findings, we included the results from the ISOS cohort in a meta-analysis. Results are reported as odds ratios (OR) with 95% confidence intervals. Results: We included 44 814 patients from 497 hospitals in 27 countries in the ISOS analysis. There were 40 245 (89.8%) patients exposed to the checklist, whilst 7508 (16.8%) sustained ≥1 postoperative complications and 207 (0.5%) died before hospital discharge. Checklist exposure was associated with reduced mortality [odds ratio (OR) 0.49 (0.32–0.77); P\u3c0.01], but no difference in complication rates [OR 1.02 (0.88–1.19); P=0.75]. In a systematic review, we screened 3732 records and identified 11 eligible studies of 453 292 patients including the ISOS cohort. Checklist exposure was associated with both reduced postoperative mortality [OR 0.75 (0.62–0.92); P\u3c0.01; I2=87%] and reduced complication rates [OR 0.73 (0.61–0.88); P\u3c0.01; I2=89%). Conclusions: Patients exposed to a surgical safety checklist experience better postoperative outcomes, but this could simply reflect wider quality of care in hospitals where checklist use is routine
Critical care admission following elective surgery was not associated with survival benefit: prospective analysis of data from 27 countries
- Author
- A T Landers
- Aaron Lawson McLean
- Abbey Paton
- Abdel Razzaq Khalaf
- Abdul Hafiz Alias
- Abdurrahman Ahmad
- Abegail Salvana
- Abigail Keen
- Abigail Patrick
- Abraham Hulst
- Acela G Lopez
- Adam Evans
- Adam Rehak
- Adamu Muhammad Sarki
- Ade Nurkacan Dursin
- Ade Susanti
- Adela Ruiz
- Adeline Rankin
- Ademola Talabi
- Adenekan Adetoye
- Adeoluwa Tayo
- Adeyinka Ademola
- Aditi Kulkarni
- Aditi Naik
- Aditi Shrivastava
- Adriana Krepil
- Adrianna Woolsey
- Adrianna Woolsey
- Adrienne Carr
- Afolabi Owojuyigbe
- Aggeliki Bairaktari
- Agoritsa Tsioka
- Agostino Roasio
- Ahamed Khader
- Ahmad Sufian Ab Rahman
- Ahmed Ahmed
- Ahmed El-Sayed
- Ahmed Saloojee
- Ahmed Sayeed
- Aida Tantri
- Aida Tantri
- Aikaterini Chatzimichali
- Aikaterini Kyparissi
- Aikaterini Makatounaki
- Aisling Clarkson
- Ajay Gupta
- Akanmu Durodola
- Akbar Vohra
- Akbar Vohra
- Akbar Vohra
- Akbar Vohra
- Akram Fuad
- Alae Conradie
- Alasdair Scott
- Alastair Rose
- Alba Perez Gonzalez
- Albert Tsui
- Alberto Lisi
- Alberto Premoli
- Alberto Ramirez
- Alberto Zangrillo
- Alda Martins
- Aleaxandra Moustaka
- Alejandra Romero Rodrigo
- Alejandro Duca
- Alejandro Suarez-de-la-Rica
- Aleksandr Iurin
- Aleksandr Molkov
- Aleksandr Samoilenko
- Aleksandr Tchekulaev
- Alessandra Bettinelli
- Alessandro Gatta
- Alessandro Marchesi
- Alex Looseley
- Alex Ragan
- Alexander Bates
- Alexander Chan
- Alexander Durst
- Alexander Fowler
- Alexander Freethy
- Alexander Ishimaru
- Alexander Kulikov
- Alexander Tolmasov
- Alexandra Abrunhosa
- Alexandra Charlalampidoy
- Alexandra Dumitrescu
- Alexandra Papaioannou
- Alexandra Torborg
- Alexandra Williams
- Alexandra Wolfer
- Alexandra Wolfer
- Alexandre Ouattara
- Alexandros Andreou
- Alexey Karelov
- Alfonso Munoz-López
- Alhafidz Hamdan
- Alhassan Datti Mohammed
- Ali Elabib
- Ali Vahedi
- Aliaksandra Parashchanka
- Alice Stevens
- Alifia Tameem
- Alison Donna
- Alison Ghosh
- Alison Knaggs
- Alison Liddle
- Alison Paton
- Alison Wilson
- Alistair Hellewell
- Alycon Walker
- Alyson Andrew
- Amabra Dodiyi-Manuel
- Amanda Cowton
- Amanda Datson
- Amanda Finch
- Amanda Jansen van Vuuren
- Amanda Lofting
- Amanda Lyle
- Amanda Miñana
- Amos Obobolo
- Amy Stevens
- Ana Cristina Miranda Martins Costa
- Ana Flavia Brotto
- Ana Izquierdo Palomares
- Ana Margarida Santos
- Ana Maria Vilela Dos Santos
- Anahi Perlas
- Anastasia Koutsikou
- Anastasia Spartinou
- Anastasia Vachlioti Vachlioti
- Anastasios Katsourakis
- Anders Oldner
- Andre Bernard
- Andre Bernard
- Andre Bernard
- Andrea Sibilio
- Andrea Stocker
- Andreas Asimakos
- Andreas Eichwalder
- Andreas Filippopoulos
- Andreas Fleischer
- Andreas Flossos
- Andreas Hoeft
- Andreas Hoeft
- Andreas Weyland
- Andreea Balanescu
- Andreea Stefan
- Andreu Cueva
- Andrew Barnett
- Andrew Berg
- Andrew Biffen
- Andrew Brennan
- Andrew Brown
- Andrew Burtenshaw
- Andrew Claxton
- Andrew Cruikshanks
- Andrew Donovan
- Andrew Macalister Hall
- Andrew McDonald
- Andrew Milne
- Andrew Pool
- Andrew Ratcliffe
- Andrew Rhodes
- Andrew Selman
- Andrew Smith
- Andrew Suen
- Andrew Suen
- Andrew Suen
- Andrew Swain
- Andrew Torrance
- Andrew Woodgate
- Andrey Lubnin
- Andri Kurnia
- Andriy Krystopchuk
- Andromachi Efthymiadi
- Andy Kwok
- Anette Barbre Pedersen
- Angela Freschini
- Angela King
- Angela Morgan
- Angela Pinder
- Angela Sanchez
- Angelantonio Pascazio
- Angeliki Tsagkaraki
- Angelo Benevento
- Angelo Porto
- Angels Lozano
- Angie Dempster
- Angus Turner
- Angus Turner
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- Tarek Bejia
- Tariq Deen
- Tatiana Lefaki
- Tatiana Slepova
- Tauqeer Husain
- Tejal Dave
- Temlett Emma
- Tengku Alini Tengku Lih
- Teresa Branco
- Teresa Rotunno
- Terry Martin
- Tesuven K Naidu
- Thais Creary
- Thalissa Hermínia Baio
- Thandinkosi E Madiba
- Thelma Commey
- Theodora Christodoulopoulou
- Theodora Melissopoulou
- Theodosios Theodosopoulos
- Theoniki Paraforou
- Theonymfi Papavasilopoulou
- Theophilos Rozenberg
- Thiago Motta Netto
- Thinagrin Dhasarthun Naidoo
- Thomas Bührer
- Thomas Daubeny
- Thomas Egan
- Thomas Hillermann
- Thomas Hopkins
- Thomas Hughes
- Thomas Jared McCormick
- Thomas Jared McCormick
- Thomas Mayrhofer
- Thomas McCormick
- Thomas Mencke
- Thomas Owen
- Thomas Parsons
- Thomas Smith
- Thuli Biyase
- Tiago do Nascimento Cabral
- Tian Yu
- Tianlong Wang
- Tianqin Yang
- Tianzhao Zheng
- Tim Cook
- Tim Short
- Timothy Jones
- Timothy McCulloch
- Timothy Salmond
- Tina Kobborg
- Ting Zhao
- Tingju Hu
- Tinuolac Adigun
- Tjokorda Gde Agung Senapathi
- Tokunbo Olajumoke
- Tom Abbott
- Tom Burrows
- Tom Jacobs
- Tom Jowitt
- Tom Lawson
- Tom Lawton
- Tom van Zundert
- Tonia Onyeka
- Tony Smith
- Tony Wong
- Tracey Hodgkiss
- Tracey Lowery
- Tracey Nolan
- Tracey Nolan
- Tracey Roberts
- Tracy Lam
- Tracy Norton
- Tracy-Lee Jansen
- Tressy Pitt-Kerby
- Troy Wildes
- Tse Siang Tan
- Tunde Osinaike
- Ucu Nurhadiat Abidin
- Ulf Kessler
- Ulrich Goebel
- Ulrika Winstone
- Uma Shastri
- Umar Musa Sule
- Ummi Azmira Ahmad Azam
- Urs Zingg
- Utara Hartawan Utara
- Vaia Aliki Rompou
- Valentin Tutunaru
- Valentina Paola Plumari
- Valentina Testa
- Valentina Tulupova
- Valerie Banner-Goodspeed
- Valerie Serra Maudet
- Valerie Smit-Fun
- Valeriy Levin
- Vandana Agarwal
- Vanessa Beavis
- Vanessa Beavis
- Vanessa Beavis
- Vanessa Nesbitt
- Varvara Vanessa Gardikou
- Vasileia Nyktari
- Vasileios Despotidis
- Vasileios Kalles
- Vasileios Ourailoglou
- Vasilios Bouris
- Vasilios Koulouras
- Veerle Van Mossevelde
- Vera Guttenthaler
- Veronica Cherrett
- Veronika Cakova
- Vicari Sottosanti
- Vicente Chisbert Cuenca
- Vicky Hills
- Victor Anillo
- Victor Aspelund Liljequist
- Victor Ionita
- Victor Raji
- Victoria Bennett
- Victoria Boggiano
- Victoria Freeman
- Victoria Frost
- Victoria Lambourne
- Victoria Martinson
- Victoria Phelps
- Vieri Parrini
- Vikas Kaura
- Vilavan Koompirochana
- Vimal Hariharan
- Vincent Chan
- Vineshykaa Ramesh Kumar
- Vinícius Nascimento
- Vishal Narwani
- Vishendran Govindasamy
- Vivek Sinha
- Vivesh Rughubar
- Vlad Kushakovsky
- Vladimir Kretov
- Vladislav Belskiy
- Vukani T Manzini
- Vítor Miguel Pinho-Oliveira
- Wai Cheong Soon
- Wai Kit Jacky Chan
- Wangpin Xiao
- Warren Paul Kuhn
- Wei Ren
- Wei Xiao
- Weihong Zhao
- Weilin Sung
- Weilu Zhao
- Weiwei Zhang
- Weixing Wang
- Wendy Bertram
- Wendy Joan Barrett
- Weng Ken Chan
- Wenhui Huang
- Werner Schmid
- Werner Schmid
- Weslley Mendes
- Widnyana Made Wid
- William Almeida
- William Foers
- William Peat
- Wilson Binh Quan Huynh
- Wilson Fabio Serna Martínez
- Wilton van Klei
- Wing LamWong
- Wing Sze Li
- Wing Yan Lam
- Wiryana Made Wir
- Wolfgang Buhre
- Wolfgang Buhre
- Wujun Geng
- Xenia Souvatzis
- Xian-Jin Zhou
- Xianfu Lu
- Xiangming Fang
- Xianwen Hu
- Xiao Hong Wen
- Xiaocui Lv
- Xiaodong Ge
- Xiaodong Qiu
- Xiaoguang Zhang
- Xiaohua Zou
- Xiaolan Hu
- Xiaolin Zhang
- Xiaomao Zhu
- Xiaoqin Li
- Xiaoyan Zhang
- Xiaoying Li
- Xiaoying Zhao
- Xiaoyu Li
- Xiaoyun Shi
- Xiapei Xiong
- Xin He
- Xindan Du
- Xinjian Lu
- Xinmei Jiang
- Xinyu Qi
- Xiu-Li Wang
- Xiumei Song
- Xiuxiu Zhuang
- Xuewu Lin
- Xuming Hu
- Yan Jing
- Yan Leng
- Yan Pan
- Yan Zhang
- Yana Ilyina
- Yanbing Bi
- Yanfei Xia
- Yang Liu
- Yang Yang
- Yangwen Ou
- Yangyang Han
- Yanling Li
- Yanming Huang
- Yanqiu Ai
- Yapping Zhang
- Yaqi Li
- Yaqiu Chen
- Yassr Al-Soudaine
- Yavor Metodiev
- Yazhou Wen
- Yazhuo Yuan
- Ye Zhang
- Yelong Ren
- Yemi Adelaja
- Yetong Li
- Yew Ching Lee
- Yi Liu
- Yi Zhong
- Yi Zhu
- Yijiao Chen
- Yijun Chen
- Yik Lam Chan
- Ying Cao
- Yingfen Xiong
- Yingping Liang
- Yixiu Yan
- Yiyi Shi
- Yonghao Yu
- Yongjie Chen
- Yongqing Guo
- Yongtao Sun
- Yongzhong Tang
- Yoni van Duivenvoorde
- Youliang Tong
- Yousif Saeed
- Yousra Ahmad
- Yu Fan
- Yu Sun
- Yuan Hsuan Chang
- Yuan Liang Woon
- Yuan Zhang
- Yuanming Pan
- Yuanyuan Pan
- Yue Fei
- Yuehong Qi
- Yuejiang Liu
- Yuelan Wang
- Yugang Shi
- Yuhong Li
- Yuksel Gercek
- Yun Bai
- Yun Ren
- Yunbin Fu
- Yunchang Mo
- Yunfei Cai
- Yunlin Feng
- Yunzhi Ling
- Yurui Yao
- Yushio Cheing
- Yusuf Ameer
- Yuting Wang
- Yves Jaquet
- Yvonne Hack
- Yvonne Selibea
- Zaheer Moolla
- Zaid Makzal
- Zane Farina
- Zhang Chen
- Zhen Dan Peng
- Zhen Wang
- Zhen Wang
- Zheng Guo
- Zhengyuan Liu
- Zhenrong Ji
- Zhi Wang
- Zhipeng Wang
- Zhipeng Zhu
- Zhisong Li
- Zhiting Wen
- Zhong-Yuan Xia
- Zhongming Cao
- Zi-Ying Shen
- Zin Nico
- Ziqiang Miao
- Zoe Davies
- Zoe Drinkwater
- Zoe Whitman
- Zulkarnain Hamzah
- Álvaro Réa-Neto
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
This was an investigator initiated study funded by Nestle Health Sciences through an unrestricted research grant, and by a National Institute for Health Research (UK) Professorship held by RP. The study was sponsored by Queen Mary University of London