238 research outputs found

    Intellectual Property Rights and the Digital Era: Argentina and Brazil

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    Gênero e sexualidade: estamos no canto do ringue?

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    Escrever sobre o panorama atual das políticas envolvendo gênero e sexualidade leva-nos a estados de espírito muito diversos: ora ficamos próximas à melancolia e ao desânimo profundo, ora nos alentamos com a certeza de que processos e atores que já foram postos em marcha não recuarão tão facilmente. Recentemente, em uma atividade promovida pelos alunos do programa de pós- -graduação do qual ambas somos professoras, Maria Elvira Díaz Benítez valeu- -se da metáfora do boxe para tratar dos golpes e contragolpes que têm sido desferidos nos últimos tempos na seara dos direitos e políticas envolvendo gênero e sexualidade. Dando seguimento a isso, indagamo-nos: em que ponto da batalha ou em que lugar do ringue se encontram as diferentes perspectivas sobre gênero e sexualidade no cenário político em que vivemos

    A methodology to determine size and shape of plots for sugarcane plantation

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    Brazil is the largest sugarcane producer in the world and the leader in the production of sugar and ethanol. Although sugarcane has become an important factor in the Brazilian economy, cultivation has presented many issues, for example, the problems due to burning before the manual harvest. The Brazilian authorities have approved a law that prohibits this practice and mechanized harvesting has thus become the most fitting approach. Given this development, areas for sugarcane plantation must be properly rebuilt to accommodate the new way of harvesting. The main characteristic demanded of sugarcane plots to use harvesting machines is that they must be rectangular. In the present paper, we propose a methodology for dividing the plantation area into plots and planning their allocation so as to accommodate mechanized harvesting. In view of the requirement for plots to be rectangular, we represented this problem as a two-dimensional cutting problem, and to find a solution we adopted the AND/OR graph approach. The computational experiments were conducted using real cases, and the proposed strategy was shown to perform well

    Study of membrane potential in T lymphocytes subpopulations using flow cytometry

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    <p>Abstract</p> <p>Background</p> <p>Ion channels are involved in the control of membrane potential (ψ) in a variety of cells. The maintenance of ψ in human T lymphocytes is essential for T-cell activation and was suggested to depend mostly on the voltage-gated Kv1.3 channel. Blockage of Kv1.3 inhibits cytokine production and lymphocyte proliferation <it>in vitro </it>and suppresses immune response <it>in vivo</it>. T lymphocytes are a heterogeneous cell population and the expression of Kv1.3 varies among cell subsets. Oxonol diBA-C4-(3) was used to determine ψ by flow cytometry. The presence of distinct T cell subsets was evaluated by immunophenotyping techniques and the contribution of Kv1.3 channels for the maintenance of ψ was investigated using selective blockers.</p> <p>Results</p> <p>The distribution of ψ in T lymphocytes varied among blood donors and did not always follow a unimodal pattern. T lymphocytes were divided into CD3<sup>+</sup>/CD45RO<sup>- </sup>and CD3<sup>+</sup>/CD45RO<sup>+ </sup>subsets, whose peak channel values of ψ were -58 ± 3.6 mV and -37 ± 4.1 mV, respectively. MgTX (specific inhibitor of Kv1.3 channels) had no significant effect in the ψ of CD3<sup>+</sup>/CD45RO<sup>- </sup>subsets but depolarized CD3<sup>+</sup>/CD45RO<sup>+ </sup>cells to -27 ± 5.1 mV.</p> <p>Conclusion</p> <p>Combination of optical methods for determination of ψ by flow cytometry with immuophenotyping techniques opens new possibilities for the study of ion channels in the biology of heterogeneous cell populations such as T lymphocyte subsets.</p

    Design de moda na periferia

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    As periferias brasileiras contam vários grupos organizados e fortemente atuantes dentro do segmento de vestuário e artesanato. Motivados pela dificuldade em obter colocação dentro do mercado formal de trabalho, boa parte da população tem encontrado na atividade informal, uma alternativa viável para sua sobrevivência

    A “Mágica” Social do Designer

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    O artesanato tem tido uma crescente revalorização, possibilitando o resgate da tradição cultural brasileira, consolidando-se também como uma importante alternativa no combate a desigualdade social, à medida que promove geração de emprego e renda. Conforme Lima e Azevedo

    Produção artesanal x timing da moda

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    O artesanato tem tido uma crescente revalorização, possibilitando o resgate da tradição cultural brasileira, trazendo mais qualidade de vida e geração de renda e emprego para várias comunidades produtivas espalhadas pelo país. Esses avanços conquistados são devidos em grande parte, à atuação de programas de incentivo à produção artesanal em parceria com o Design. Somente através de intervenções aplicadas sob a ótica da gestão de Design foi possível, otimizar produtos e processos, caminhando em direção a produtos de artesanato de alta qualidade e orientados para a satisfação do público consumidor

    Evaluation of Clinical Variables Associated with Increased Carotid Intima-Media Thickness in Middle-Aged Hypertensive Women

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    It has been previously documented that carotid intima-media thickness (cIMT) is a predictor of cardiovascular disease. The aim of this study was to identify clinical parameters associated with an increased cIMT treated hypertensive women. Female patients (n = 116) with essential hypertension, aged 40–65 years, were included in this study. Vascular ultrasound was performed and the patients were divided into two groups according to the values of cIMT (< or ≥0.9 mm). Patients with greater cIMT presented significantly higher systolic blood pressure and pulse pressure. Serum HDL-cholesterol was significantly lower and CRP was significantly higher in the same group. There was a significant correlation between cIMT and age (r = 0.25, P = 0.007), systolic blood pressure (r = 0.19, P = 0.009), pulse pressure (r = 0.30, P = 0.001), and LDL-cholesterol (r = 0.19, P = 0.043). cIMT was correlated to CRP (r = 0.31, P = 0.007) and negatively correlated to HDL-cholesterol (r = 0.33, P = 0.001). In logistic regression, only HDL-cholesterol, CRP, and pulse pressure were shown to be independent variables associated to increased cIMT. In conclusion, pulse pressure, HDL-cholesterol, and CRP are variables correlated with cIMT in treated hypertensive women

    Study of the interlanguage of deafs, users of Brazilian Sign Language, in the acquisition of Brazilian Portuguese

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    The study examines the interlanguage of deafs (users of the Brazilian Sign Language) learning Portuguese as a second language. In particular, the manifestation of bare nominals (in the singular) and definite generics (in the singular and in the plural) is taken into consideration. The high frequency of singular bare nouns is analysed as L1 transfer, given that LSB does not have (definite) articles. Assuming that number is an interpretable feature on the generic definite DP, it is proposed that the linguistic development takes place through the syntactic mapping of morpho(phono)logical properties of the (plural) definite article on the functional head Number. KEYWORDS: Language acquisition. Brazilian Sign Language. L2 Portuguese. Definite generics. Bare noun.O estudo examina a interlíngua de surdos (usuários de Língua de Sinais Brasileira) aprendizes de português como segunda língua, considerando, em particular, a manifestação de definidos genéricos (no singular e no plural) e de nominais nus (no singular). A alta frequência de nominal nu no singular é analisada como transferência de L1, já que a LSB não possui artigos. Partindo-se da hipótese de que a categoria de número é interpretável no DP definido genérico, propõe-se que o desenvolvimento linguístico ocorre mediante o mapeamento de propriedades morfo(fono)lógicas do artigo definido (plural) na projeção do núcleo funcional Número. PALAVRAS-CHAVE: Aquisição de língua. Língua de sinais brasileira. Português L2. Definido genérico. Nominal nu.ABSTRACT The study examines the interlanguage of deafs (users of the Brazilian Sign Language) learning Portuguese as a second language. In particular, the manifestation of bare nominals (in the singular) and definite generics (in the singular and in the plural) is taken into consideration. The high frequency of singular bare nouns is analysed as L1 transfer, given that LSB does not have (definite) articles. Assuming that number is an interpretable feature on the generic definite DP, it is proposed that the linguistic development takes place through the syntactic mapping of morpho(phono)logical properties of the (plural) definite article on the functional head Number. KEYWORDS: Language acquisition. Brazilian Sign Language. L2 Portuguese. Definite generics. Bare noun

    Áreas do conhecimento em que as universidades do Sul do Brasil possuem patentes concedidas

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    The objective of the study is to analyze the patents granted in thepublic universities from the South of Brazil in the knowledge areas – where theycome from and in which areas they are classified according to the InternationalPatent Classification -, and as specific objectives to map the public universitiesfrom the South of the country and its patents; identify International PatentClassification areas and knowledge areas of the National Council for Scientificand Technological Development , to which the patents belong to; and establishthe contribution relation that each knowledge area of National Council forScientific and Technological Development performs in each International PatentClassification area. The patents survey was conducted in the database of theNational Institute of Industrial Property. After collecting the classificationnumber, the National Council for Scientific and Technological Developmenttable knowledge areas were crossed. The results recovered 11 public universitiesthat presented 68 granted patents. The section of the International PatentClassification that presented the largest number of patent concessions was the"C - Chemistry; Metallurgy", with 25 registrations. The knowledge areas ofNational Council for Scientific and Technological Development that publishedin the section were: Biochemistry, Civil Engineering, Materials andMetallurgical Engineering, Chemical Engineering, Sanitary Engineering andChemistry. The big area of "Engineering" was the one that obtained the largest volume of patents, totaling 24. The schooling of the most productive inventors,who belong to the Federal University of Rio Grande do Sul, concentrated in thearea of Chemistry.O estudo tem como objetivo geral analisar as patentes concedidas nas universidades públicas do Sul do Brasil no que se refere às áreas do conhecimento – de onde provêm, e em quais áreas elas são classificadas de acordo com a Classificação Internacional de Patentes - e como objetivos específicos mapear as universidades públicas do Sul do país e suas patentes; identificar as áreas da Classificação Internacional de Patentes e as áreas do conhecimento do Conselho Nacional de Desenvolvimento Científico e Tecnológico, às quais as patentes pertencem; e estabelecer relação de contribuição que cada área do conhecimento do Conselho Nacional de Desenvolvimento Científico e Tecnológico realiza em cada área da Classificação Internacional de Patentes. O levantamento das patentes foi realizado na base de dados do Instituto Nacional da Propriedade Industrial. De posse do número da classificação, realizou-se o cruzamento com as áreas do conhecimento da tabela do Conselho Nacional de Desenvolvimento Científico e Tecnológico. Os resultados reuniram 11 universidades públicas que apresentaram 68 patentes concedidas. A seção da Classificação Internacional de Patentes que apresentou maior número de concessões de patentes foi a “C - Química; Metalurgia”, com 25 registros. As áreas de conhecimento do  Conselho Nacional de Desenvolvimento Científico e Tecnológico que publicaram na seção foram: Bioquímica, Engenharia Civil, Engenharia de Materiais e Metalúrgica, Engenharia Química, Engenharia Sanitária e Química. A grande área "Engenharias" foi a que obteve o maior volume de patentes, totalizando 24. A formação dos inventores mais produtivos, que pertencem à Universidade Federal do Rio Grande do Sul, concentrou-se na área de Química.
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