Ion sorption onto hydrous ferric oxides: Effect on major element fluid chemistry at Aspo, Sweden

The observed variability of fluid chemistry at the Aespoe Hard Rock Laboratory is not fully described by conservative fluid mixing models. Ion exchange may account for some of the observed discrepancies. It is also possible that variably charged solids such as oxyhydroxides of Fe can serve as sources and sinks of anions and cations through surface complexation. Surface complexation reactions on hydrous ferric oxides involve sorption of both cations and anions. Geochemical modeling of the surface chemistry of hydrous ferric oxides (HFOs) in equilibrium with shallow HBH02 and deep KA0483A waters shows that HFOs can serve as significant, pH-sensitive sources and sinks for cations and anions. Carbonate sorption is favored especially at below-neutral pH. A greater mass of carbonate is sorbed onto HFO surfaces than is contained in the fluid when 10 g goethite, used as a proxy for HFOs, is in contact with 1 kg H{sub 2}O. The masses of sorbent required to significantly impact fluid chemistry through sorption/desorption reactions seem to be reasonable when compared to the occurrences of HFOs at Aespoe. Thus, it is possible that small changes in fluid chemistry can cause significant releases of cations or anions from HFOs into the fluid phase or, alternately, result in uptake of aqueous species onto HFO surfaces. Simulations of the mixing of shallow HBH02 and native KA0483A waters in the presence of a fixed mass of goethite show that surface complexation does not cause the concentrations of Ca, Sr, and SO{sub 4} to deviate from those that are predicted using conservative mixing models. Results for HCO{sub 3} are more difficult to interpret and cannot be addressed adequately at this time

Wireless Sensor Network Deployment for Monitoring Soil Moisture Dynamics at the Field Scale

AbstractWe describe the deployment of a Wireless Sensor Network (WSN), composed of 135 soil moisture and 27 temperature sensors, in an apple tree orchard of about 5000 m2, located in the municipality of Cles, a small town in the Alpine region, northeastern Italy. The orchard is divided into three parcels each one subjected to a different irrigation schedule. The objective of the present work is to monitor soil moisture dynamics in the top soil to a detail, in both space and time, suitable to analyze the interplay between soil moisture dynamics and plant physiology. The deployment consists of 27 locations (verticals) connected by a multi hop WSN, each one equipped with 5 soil moisture sensors deployed at the depths of 10, 20, 30, 50 and 80 cm, and a temperature sensor at the depth of 20 cm. The proposed monitoring system is based on totally independent sensor nodes, which allow both real time and historic data management and are connected through an input/output interface to a WSN platform. Meteorological data are monitored by a weather station located at a distance of approximately 100 m from the experimental site.Great care has been posed to calibration of the capacitance sensors, both in the laboratory, with soil samples, and on site, after deployment, in order to minimize the noise caused by small oscillations in the input voltage and uncertainty in the calibration curves. In this work we report the results of a preliminary analysis on the data collected during the growing season 2009. We observed that the WSN greatly facilitates the collection of detailed measurements of soil moisture, thereby increasing the amount of information useful for exploring hydrological processes, but they should be used with care since the accuracy of collected data depends critically on the capability of the system to maintain constant the input voltage and on the reliability of calibration curves. Finally, we studied the spatial and temporal distribution of soil moisture in all the irrigated parcels, and explored how different irrigation schedules influence orchard's production

Interactions of Uranium and Neptunium With Cementitious Materials Studied by XAFS

We have investigated the interaction of U(VI) and Np(V) actinide ions with cementitious materials that are relevant to nuclear waste repositories using X-Ray Absorption Fine Structure (XAFS) Spectroscopy. The actinide ions were individually loaded onto untreated as well as hydrothermally treated cements. The mixtures were then equilibrated at varying pH's for a period of approximately 6 months. In all cases uranium was introduced in the form of aqueous uranyl ion, UO{sub 2}{sup 2+}, and was observed to remain in this form based on the Near Edge (XANES) spectra. The uranium samples show evidence of interactions with both treated and untreated cements at all pH's, with uranyl interacting with the cement mineral phases (i.e., SiO{sub 2}) through an inner-sphere mechanism where oxygen atoms in the equatorial plane of the uranyl ion are shared with the mineral surface. In contact with the hydrothermally treated cement, the uranyl ions are also observed to form oligomeric species, proving that hydrothermal treatment of the concrete has a significant effect on the structural bonding characteristics of uranyl on the concrete. Neptunium was introduced as the neptunyl ion, NpO{sub 2}{sup +}, and was observed to undergo a reduction from Np(V) to Np(IV). Percent reduction was calculated from both component analysis of the XANES region and by curve fitting to the EXAFS region. Results from both methods were in good agreement and showed ca. 15% of Np(V) is reduced to Np(IV) in the fresh sample. In comparison, the other samples showed higher reduction rates of between 40% and 65%. Reduction was thus observed to occur over a relatively slow time scale based on XAFS data collected from a ''fresh'' sample (aged for 1 month). No Np-Np interactions were observed in the EXAFS spectra which makes surface precipitation of Np{sup 4+} phases an unlikely mechanism for sorption

Metabolic profiles of whole, parotid and submandibular/sublingual saliva

The detection of salivary molecules associated with pathological and physiological alterations has encouraged the search of novel and non-invasive diagnostic biomarkers for oral health evaluation. While genomic, transcriptomic, and proteomic profiles of human saliva have been reported, its metabolic composition is a topic of research: metabolites in submandibular/sublingual saliva have never been analyzed systematically. In this study, samples of whole, parotid, and submandibular/ sublingual saliva from 20 healthy donors, without dental or periodontal diseases, were examined by nuclear magnetic resonance. We identified metabolites which are differently distributed within the three saliva subtypes (54 in whole, 49 in parotid, and 36 in submandibular/sublingual saliva). Principal component analysis revealed a distinct cluster for whole saliva and a partial overlap for parotid and submandibular/sublingual metabolites. We found exclusive metabolites for each subtype: 2-hydroxy-3-methylvalerate, 3-methyl-glutarate, 3-phenylpropionate, 4-hydroxyphenylacetate, 4-hydroxyphenyllactate, galactose, and isocaproate in whole saliva; caprylate and glycolate in submandibular/sublingual saliva; arginine in parotid saliva. Salivary metabolites were classified into standard and non-proteinogenic amino acids and amines; simple carbohydrates; organic acids; bacterial-derived metabolites. The identification of a salivary gland-specific metabolic composition in healthy people provides the basis to invigorate the search for salivary biomarkers associated with oral and systemic diseases

Fracture Permeability Evolution in Desert Peak Quartz Monzonite

Fracture flow experiments are being conducted on quartz monzonite core from the Desert Peak East EGS site, Churchill County, Nevada. The flow experiments are conducted at temperatures of 167-169 C and 5.5 MPa confining pressure through artificial fractures. Two injection fluids, a saline solution and a silica-bearing solution, have been used to date. Flow rates are typically 0.02 mL/min, but other rates have been used. The fracture surfaces are characterized with a contact profilometer. The profilometry data demonstrate that it is possible to fabricate statistically similar fracture surfaces and enable us to map aperture variations, which we use in numerical simulations. Effluent samples are collected for chemical analysis. The fluid pressure gradient is measured across the specimen and effective hydraulic apertures are calculated. The experiments show a reduction in permeability over time for both injection fluids, but a more rapid loss of permeability was observed for the silica-bearing solution. The calculated hydraulic aperture is observed to decrease by 17% for the saline solution and 75% for the silica-bearing fluid, respectively. Electrical resistivity measurements, which are sensitive to the ionic content of the pore fluid, provide additional evidence of fluid-rock interactions

Coffee bean extracts rich and poor in kahweol both give rise to elevation of liver enzymes in healthy volunteers

BACKGROUND: Coffee oil potently raises serum cholesterol levels in humans. The diterpenes cafestol and kahweol are responsible for this elevation. Coffee oil also causes elevation of liver enzyme levels in serum. It has been suggested that cafestol is mainly responsible for the effect on serum cholesterol levels and that kahweol is mainly responsible for the effect on liver enzyme levels. The objective of this study was to investigate whether coffee oil that only contains a minute amount of kahweol indeed does not cause elevation of liver enzyme levels. METHODS: The response of serum alanine aminotransferase (ALAT) and aspartate aminotransferase (ASAT) to Robusta coffee oil (62 mg/day cafestol, 1.6 mg/day kahweol) was measured in 18 healthy volunteers. RESULTS: After nine days one subject was taken off Robusta oil treatment due to an ALAT level of 3.6 times the upper limit of normal (ULN). Another two subjects stopped treatment due to other reasons. After 16 days another two subjects were taken off Robusta oil treatment. One of those subjects had levels of 5.8 ULN for ALAT and 2.0 ULN for ASAT; the other subject had an ALAT level of 12.4 ULN and an ASAT level of 4.7 ULN. It was then decided to terminate the study. The median response of subjects to Robusta oil after 16 days was 0.27 ULN (n = 15, 25(th),75(th )percentile: 0.09;0.53) for ALAT and 0.06 ULN (25(th),75(th )percentile -0.06;0.22) for ASAT. CONCLUSIONS: We conclude that the effect on liver enzyme levels of coffee oil containing hardly any kahweol is similar to that of coffee oil containing high amounts of kahweol. Therefore it is unlikely that kahweol is the component of coffee oil that is responsible for the effect. Furthermore, we conclude that otherwise unexplained elevation of liver enzyme levels observed in patients might be caused by a switch from consumption of filtered coffee to unfiltered coffee

eRAPID electronic patient self-Reporting of Adverse-events: Patient Information and aDvice: a pilot study protocol in pelvic radiotherapy.

Background: An estimated 17,000 patients are treated annually in the UK with radical radiotherapy (RT) for pelvic cancer. New treatment approaches in RT have increased survivorship and changed the subjective toxicity profile for patients who experience acute and long-term pelvic-related adverse events (AE). Multi-disciplinary follow-up creates difficulty for monitoring and responding to these events during treatment and beyond. Originally developed for use in systemic oncology therapy eRAPID (electronic patient self-Reporting of Adverse-events: Patient Information and aDvice) is an online system for patients to report AEs from home. eRAPID enables patient data to be integrated into the electronic patient records for use in clinical practice, provides patient management advice for mild and moderate AE and advice to contact the hospital for severe AE. The system has now been developed for pelvic RT patients, and we aim to test the intervention in a pilot study with staff and patients to inform a future randomised controlled trial (RCT). Methods: Eligible patients are those attending St James's University hospital cancer centre and The Christie Hospital Manchester undergoing pelvic radiotherapy+/-chemotherapy/hormonotherapy for prostate, lower gastrointestinal and gynaecological cancers. A prospective 1:1 randomised (intervention or usual care) parallel group design with repeated measures and mixed methods will be employed. We aim to recruit 168 patients following recommendations for sample size estimates for pilot studies. Participants using eRAPID will report AE (at least weekly) from home weekly for 6 weeks and 6 weeks post-treatment (12-week total) then at 18 and 24 weeks. Hospital staff will review eRAPID reports and use information during consultations. Notifications will be sent to the relevant clinical team when severe symptoms are reported. We will measure patient-reported outcomes using validated questionnaires (Functional Assessment in Cancer Therapy Scale-General (FACT-G), European Organisation for Research and Treatment of Cancer Core Quality of Life questionnaire (EORTC-QLQ-C30), process of care impact (hospital records of patient contacts and admissions) and economic variables (EQ5D-5L, patient use of resources)). Staff and patient experiences will be explored via semi-structured interviews. Discussion: The objectives are to establish feasibility, recruitment, integrity of the system and attrition rates, determine effect sizes and aid selection of the primary outcome measure for a future RCT. We will also refine the intervention by exploring staff and patient views. The overall goal of this complex intervention is to improve the safe delivery of cancer treatments, enhance patient care and standardise documentation of AE within the clinical datasets. Trial registration: ClinicalTrials.gov NCT02747264

Measurement of event shapes in deep inelastic scattering at HERA

Inclusive event-shape variables have been measured in the current region of the Breit frame for neutral current deep inelastic ep scattering using an integrated luminosity of 45.0 pb^-1 collected with the ZEUS detector at HERA. The variables studied included thrust, jet broadening and invariant jet mass. The kinematic range covered was 10 < Q^2 < 20,480 GeV^2 and 6.10^-4 < x < 0.6, where Q^2 is the virtuality of the exchanged boson and x is the Bjorken variable. The Q dependence of the shape variables has been used in conjunction with NLO perturbative calculations and the Dokshitzer-Webber non-perturbative corrections (`power corrections') to investigate the validity of this approach.Comment: 7+25 pages, 6 figure

Angular and Current-Target Correlations in Deep Inelastic Scattering at HERA

Correlations between charged particles in deep inelastic ep scattering have been studied in the Breit frame with the ZEUS detector at HERA using an integrated luminosity of 6.4 pb-1. Short-range correlations are analysed in terms of the angular separation between current-region particles within a cone centred around the virtual photon axis. Long-range correlations between the current and target regions have also been measured. The data support predictions for the scaling behaviour of the angular correlations at high Q2 and for anti-correlations between the current and target regions over a large range in Q2 and in the Bjorken scaling variable x. Analytic QCD calculations and Monte Carlo models correctly describe the trends of the data at high Q2, but show quantitative discrepancies. The data show differences between the correlations in deep inelastic scattering and e+e- annihilation.Comment: 26 pages including 10 figures (submitted to Eur. J. Phys. C