Grounding Abstract Concepts in Action

Sensory-motor information is linguistically encoded by action verbs. Such verbs are not only used to express action concepts and events, but they are also pervasively exploited in the linguistic representation of abstract concepts and figurative meanings. In the light of several theoretical approaches (i.e., Embodied Theories, Conceptual Metaphor Theory, Image Schema Theory), this paper analyzes the mechanisms that enable action verbs to acquire abstract meanings and that motivate the symmetries (or asymmetries) in the semantic variations of locally equivalent verbs (e.g., premere and spingere; Eng., to press and to push). The research is carried out within the IMAGACT framework and focuses on a set of four Italian action verbs encoding force (i.e., premere, spingere, tirare, and trascinare; Eng., to press, to push, to pull, and to drag). The results confirm that metaphorical extensions of action verbs are constrained by the image schemas involved in the core meaning of the verbs. Additionally, the paper shows that these image schemas are responsible for the asymmetries in the metaphorical variation of action verbs pertaining to the same semantic class (i.e., force)

An Extreme Mountain Ultra-Marathon Decreases the Cost of Uphill Walking and Running

Purpose: To examine the effects of the world's most challenging mountain ultramarathon (MUM, 330 km, cumulative elevation gain of +24,000 m) on the energy cost and kinematics of different uphill gaits. Methods: Before (PRE) and immediately after (POST) the competition, 19 male athletes performed three submaximal 5-min treadmill exercise trials in a randomized order: walking at 5 km.h-1, +20%; running at 6 km.h-1, +15%; and running at 8 km.h-1, +10%. During the three trials, energy cost was assessed using an indirect calorimetry system and spatiotemporal gait parameters were acquired with a floor-level high-density photoelectric cells system. Results: The average time of the study participants to complete the MUM was 129 h 43 min 48 s (range: 107 h 29 min 24 s to 144 h 21 min 0 s). Energy costs in walking (-11.5 +/- 5.5%, P < 0.001), as well as in the first (-7.2 +/- 3.1%, P = 0.01) and second (-7.0 +/- 3.9%, P = 0.02) running condition decreased between PRE and POST, with a reduction both in the heart rate (-11.3, -10.0, and -9.3%, respectively) and oxygen uptake only for the walking condition (-6.5%). No consistent and significant changes in the kinematics variables were detected (P-values from 0.10 to 0.96). Conclusion: Though fatigued after completing the MUM, the subjects were still able to maintain their uphill locomotion patterns noted at PRE. The decrease (improvement) in the energy costs was likely due to the prolonged and repetitive walking/running, reflecting a generic improvement in the mechanical efficiency of locomotion after ~130 h of uphill locomotion rather than constraints imposed by the activity on the musculoskeletal structure and function

Familial Polyposis Coli: The Management of Desmoid Tumor Bleeding

There is currently no standard treatment for desmoid tumors (DTs) associated with familial polyposis coli (FAP). Familial adenomatous polyposis in DT patients is sometimes a life-threatening condition

Gait alterations during constant pace treadmill racewalking

Racewalking is an Olympic event requiring great endurance, and racewalkers often use treadmills in training because of the benefits of having a flat, unchanging surface where pace judgment can be learned, and because inclement weather can be avoided. The effects of fatigue associated with racewalking on a treadmill have not been studied, and could be informative with regard to the maintenance of legal technique. The aim of this study was to measure key gait variables during a physically demanding treadmill racewalk. Fourteen international racewalkers completed 10 km on an instrumented treadmill at a pace equivalent to 103% of their recent best time. Spatiotemporal and ground reaction force data were recorded at four distances. High-speed videography data were simultaneously recorded to analyze changes in knee angle between the early and late stages. Increases in step length and corresponding decreases in cadence were found, although the small changes were not considered meaningful. There was also a small increase in flight time and a small decrease in push-off force. There were no other significant changes for any other variables (including knee angles). The increase in flight time might be important given that racewalkers are not permitted a visible loss of contact and suggests that fatiguing sessions on a treadmill can lead to the adoption of non-legal technique. However, this disadvantage of treadmill training can be negated if the coach scrutinizes the athlete throughout the session, and overall the consistent technique used is of benefit with regard to learning correct form and pacing ability

Ethical Issues in the Use of Suboptimal Kidneys for Transplants: an Italian Point of View

The shortage of organs leads to the need for utilizing suboptimal kidneys for transplantation. The distinction between optimal, marginal, and suboptimal kidneys leads surgeons to face not only technical problems but also ethical and legal issues related to clinical advantages offered by the transplant of a nonstandard kidney and the acquisition of consent. Between 1999 and 2015, we performed 658 transplants, 49 (7.5%) using suboptimal kidneys. All patients were alive and with vital graft throughout follow-up. We did not encounter any major surgical complications. From a technical point of view, our experience and literature review confirm that transplant of suboptimal kidney leads to good clinical results but exposes patients to a increased risks of surgical complications. Therefore, these interventions must take place in hospitals fully prepared for this type of surgery and performed by experienced transplant surgeons with proper matching between organ and recipient. Considering the insufficient resources available, from an ethical and legal point of view, doctors play an essential role in optimizing the use of these kidneys by avoiding wastage of organs, ensuring that transplants are done in suitable patients, and that patients are fully informed and aware of the risks and benefits associated with the specific suboptimal kidney being transplanted. We believe that, in highly specialized centers, the number of suboptimal kidney transplants should be increased, as their use has shown good clinical results and carries fewer ethical issues compared with marginal kidneys. Further, suboptimal kidneys may also be proposed for use in young patients with end-stage renal disease

EXERCISE INTENSITY AND PACING STRATEGY OF A 5-KM INDOOR RACE WALK DURING A WORLD RECORD ATTEMPT: A CASE STUDY

The aim of this case study was to describe the physiological and regulatory processes, by means of heart rate (HR) monitoring and pacing strategy, in a top-level race walker (age: 32 years; height: 1.76 m; body mass: 62 kg; training volume: 130\u2013150 km\u2022wk-1) who was focused on the attainment of the 5-km indoor race walk (RW) World Record. The HRmean was 185 6 14.9 b\u2022min-1, with an HRmean/HRmax ratio of 0.96. Almost the whole race (91.8%) was performed to an intensity 6590% of the HRmax; lower intensity work was negligible (8.1%). The race profile was a reverse J-shaped pacing curve; in fact, the athlete completed the first 1,000 m in the fastest time, slowing during the middle 3,000 m, and increasing the speed during the final 1,000 m of the race. Despite the attempt failed (the athlete performed only the 2009 World leading performance, 18 minutes 23 seconds 47 tenths), these data suggest that a more linear strain distribution for the entire performance would be optimal instead of a fast-start strategy, which leads to a drastic decrement of the walking velocity. Moreover, this study supports the use of HR monitoring combined with the regulation of the effort to understand the physiological and regulatory processes during an indoor RW event

Building a corpus on Eating Disorders from TikTok: challenges and opportunities

We present two synchronic corpora of Eating Disorders (ED) related discourse on Social Media. PAC (i.e., ProAna/Anorexian Corpus) and RAC (i.e., Recovery from Ana/Anorexia Corpus) resources focus on the contents posted on TikTok, respectively, by communities promoting anorectic behavior and users sharing experiences concerning the process of recovery from their ED. We report on the corpus statistics and creation process, focusing specifically on the methodological issues raised by this novel Social Media platform