Touchez pas au grisbi, film épatant : argot, dernier cri et revendication nationale

International audienceAnalyse du film de Jacques Becker (1954), pour le replacer, par une étude iconographique de ses "objets figuratifs" (Francastel), dans son époque et en retracer les enjeux idéologiques, notamment au regard du roman initial

Creation of an open data federated platform

The goal of this thesis is to design and build a web platform that integrates access to data from several Open Data portals. This platform will be used as a tool to explore and showcase the results of different techniques of data discovery, with the goal of developing and implementing a method to efficiently detect similarities and datasets that can be joined. This thesis is highly practical, and is focused on explaining the technical decisions and implementation details behind the final tool developed. With the popularization of Open Data platforms the amount of data available on the internet is growing exponentially, and with it the question of how to extract value of such large amounts of data. This project not only looks for a way to unify the data in a single place, but also for ways to be able to explore this data, making special emphasis on ways to detect similarities between datasets. The project initially revolved around the data provided from the municipal open data portals from Barcelona and L’Hospitalet de Llobregat, but the final solution is meant to be scalable and easily adaptable to other data sources. The initial idea for this thesis was to be focused mainly on exploring methods for detecting similarity and joinability between datasets based on profiles, but during development, it became obvious that the infrastructure required to unify all the datasets and provide a tool to explore the data was not simple at all. So in the end, a big part of the thesis consists of the discussion of technical decisions made and details of the tool built for the project

Vite, mettre en scène un génocide

Dès sa création fin juillet 1915, l’ambitieuse Triangle, nouvelle maison de distribution et de production américaine, met en chantier un long-métrage de fiction intitulé The Despoiler, réunissant les meilleurs talents de la Kay Bee, unité de production sous la responsabilité de Thomas H. Ince. L’histoire met aux prises une modeste bourgade chrétienne des Balkans avec un khan moyen-oriental cruel qu’un conseiller de la Mitteleuropa n’arrive pas à canaliser. Bien que les lieux et les noms soient imaginaires et censurés, les allusions au génocide arménien sont assez claires. On ne connaît le film que d’après une copie distribuée en France en 1917, remontée par rapport à la version originale connue par le seul biais d’un découpage technique complet. En étudiant ces deux versions, et l’histoire de leur distribution, on s’efforce de retracer les rapports complexes de l’industrie cinématographique américaine avec la politique internationale lorsque les États-Unis sont neutres (1915), puis lorsqu’ils sont engagés dans le conflit (1917).From its creation at the end of July 1915, Triangle, an ambitious new American production and distribution company, got started on a feature-length fictional motion-picture entitled The Despoiler, which combined the best talents from Kay Bee, a production unit under the responsibility of Thomas H. Ince. The story opposes a modest Christian village in the Balkans with a Middle-Eastern and cruel khan that a counsellor from Mitteleuropa cannot manage to control. Even though the places and names are imaginary and censored, the allusions to the Armenian Genocide are quite plain. The film is known only from a copy distributed in France in 1917, put together again in relation to the original, itself known only by means of the complete shot list. In studying these two versions and the history of their distribution, one endeavours to go back over the complex relations between the American film industry and the country’s foreign policy at a time of neutrality (1915), and then when the USA became engaged in the conflict (1917)

Short-term temporal variations of heterotrophic bacterial abundance and production in the open NW Mediterranean Sea

International audienceWe present the vertical and temporal dynamics of total vs. particle-attached bacterial abundance and activity over a 5 week period under summer to autumn transition in NW Mediterranean Sea. By comparison to previous investigations in the same area but during different seasons, we found that total bacterial biomass and production values were consistent with the hydrological conditions of the summer-fall transition. At a weekly time scale, total bacterial biomass and production in the euphotic layers was significantly correlated with phytoplanktonic biomass. At an hourly time scale, total bacterial biomass responded very rapidly to chlorophyll-a fluctuations, suggesting a tight coupling between phytoplankton and bacteria for resource partitioning during summer-autumn transition. In contrast, no influence of diel changes on bacterial parameters was detected. Episodic events such as coastal water intrusions had a significant positive effect on total bacterial abundance and production, whereas we could not detect any influence of short wind events whatever the magnitude. Finally, we show that particle-attached bacteria can represent a large proportion (until 49%) of the total bacterial activity in the euphotic layer but display rapid and sporadic changes at hourly time scales. This study underlines the value of large datasets covering different temporal scales to clarify the biogeochemical role of bacteria in the cycling of organic matter in open seawater

De presque toutes les couleurs : Civilization (Thomas H. Ince, Raymond B. West, 1916)

Présentation des « Coloring Notes » qui accompagnent le scénario de Civilization de Thomas H. Ince et qui donnent des indications précises quant au teintage et virage des scènes.Presentation of the « Coloring Notes » accompanying the scenario for Thomas H. Ince’s Civilization, and giving precise indications about the tinting and toning of scenes

Spread Deficits in Initiation, Speed and Accuracy of Horizontal and Vertical Automatic Saccades in Dementia with Lewy Bodies

Background: Mosimann et al. (2005) reported prolongation of saccade latency of prosaccades in dementia with Lewy body (DLB). The goal of this study is to go further examining all parameters, such as rates of express latency, but also accuracy and velocity of saccades, and their variability. Methods: We examined horizontal and vertical saccades in 10 healthy elderly subjects and 10 patients with DLB. Two tasks were used: the gap (fixation target extinguishes prior to target onset) and the overlap (fixation stays on after target onset). Eye movements were recorded with the Eyelink II eye tracker. Results: The main findings were: (1) as for healthy, latencies were shorter in the gap than in the overlap task (a gap effect); (2) for both tasks latency of saccades was longer for DLB patients and for all directions; (3) express latency in the gap task was absent for large majority of DLB patients while such saccades occurred frequency for controls; (4) accuracy and peak velocity were lower in DLB patients; (5) variability of all parameters was abnormally high in DLB patients. Conclusions: Abnormalities of all parameters, latency, accuracy and peak velocity reflect spread deficits in cortical-subcortical circuits involved in the triggering and execution of saccades

Is IP-10 an Accurate Marker for Detecting M. tuberculosis-Specific Response in HIV-Infected Persons?

The suboptimal sensitivity of Interferon (IFN)-γ-based in-vitro assays, especially in immunocompromised individuals, emphasizes the need for alternative markers for diagnosing tuberculosis (TB). The objective of this study was to evaluate whether interferon-inducible protein (IP)-10, monocyte chemotactic protein (MCP)-2 and interleukin (IL)-2 can be useful biomarkers for evaluating a specific response to RD1 antigens associated to active TB disease in HIV-infected individuals.The study was carried out in India, the country with the highest TB burden in the world. Sixty-six HIV-infected individuals were prospectively enrolled, 28 with active-pulmonary-TB and 38 without. The whole blood assay based on RD1-selected peptides (experimental test) and QuantiFERON-TB Gold In tube (QFT-IT) was performed. Plasma was harvested at day-1-post-culture and soluble factors were evaluated by ELISA. The results indicate that by detecting IP-10, the sensitivity of the experimental test and QFT-antigen (75% and 85.7% respectively) for active TB was higher compared to the same assays based on IFN-γ (42.9% and 60.7% respectively) and was not influenced by the ability to respond to the mitogen. By detecting IP-10, the specificity of the experimental test and QFT-antigen (57.9% and 13.2% respectively) for active TB was lower than what was reported for the same assays using IFN-γ-detection (78.9% and 68.4% respectively). On the other side, in vitro IL-2 and MCP-2 responses were not significantly associated with active TB.HIV infection does not impair RD1-specific response detected by IP-10, while it significantly decreases IFN-γ-mediated responses. At the moment it is unclear whether higher detection is related to higher sensitivity or lower specificity of the assay. Further studies in high and low TB endemic countries are needed to elucidate this

A defective Krab-domain zinc-finger transcription factor contributes to altered myogenesis in myotonic dystrophy type 1

Myotonic dystrophy type 1 (DM1) is an RNA-mediated disorder caused by a non-coding CTG repeat expansion that, in particular, provokes functional alteration of CUG-binding proteins. As a consequence, several genes with misregulated alternative splicing have been linked to clinical symptoms. In our search for additional molecular mechanisms that would trigger functional defects in DM1, we took advantage of mutant gene-carrying human embryonic stem cell lines to identify differentially expressed genes. Among the different genes found to be misregulated by DM1 mutation, one strongly downregulated gene encodes a transcription factor, ZNF37A. In this paper, we show that this defect in expression, which derives from a loss of RNA stability, is controlled by the RNA-binding protein, CUGBP1, and is associated with impaired myogenesis—a functional defect reminiscent of that observed in DM1. Loss of the ZNF37A protein results in changes in the expression of the subunit α1 of the receptor for the interleukin 13. This suggests that the pathological molecular mechanisms linking ZNF37A and myogenesis may involve the signaling pathway that is known to promote myoblast recruitment during development and regeneratio