The correct estimate of the probability of false detection of the matched filter in the detection of weak signals. II. (Further results with application to a set of ALMA and ATCA data)

The matched filter (MF) is one of the most popular and reliable techniques to the detect signals of known structure and amplitude smaller than the level of the contaminating noise. Under the assumption of stationary Gaussian noise, MF maximizes the probability of detection subject to a constant probability of false detection or false alarm (PFA). This property relies upon a priori knowledge of the position of the searched signals, which is usually not available. Recently, it has been shown that when applied in its standard form, MF may severely underestimate the PFA. As a consequence the statistical significance of features that belong to noise is overestimated and the resulting detections are actually spurious. For this reason, an alternative method of computing the PFA has been proposed that is based on the probability density function (PDF) of the peaks of an isotropic Gaussian random field. In this paper we further develop this method. In particular, we discuss the statistical meaning of the PFA and show that, although useful as a preliminary step in a detection procedure, it is not able to quantify the actual reliability of a specific detection. For this reason, a new quantity is introduced called the specific probability of false alarm (SPFA), which is able to carry out this computation. We show how this method works in targeted simulations and apply it to a few interferometric maps taken with the Atacama Large Millimeter/submillimeter Array (ALMA) and the Australia Telescope Compact Array (ATCA). We select a few potential new point sources and assign an accurate detection reliability to these sources.Comment: 28 pages, 20 figures, Astronomy & Astrophysics, Minor changes and some typos correcte

Design and baseline characteristics of the finerenone in reducing cardiovascular mortality and morbidity in diabetic kidney disease trial

Background: Among people with diabetes, those with kidney disease have exceptionally high rates of cardiovascular (CV) morbidity and mortality and progression of their underlying kidney disease. Finerenone is a novel, nonsteroidal, selective mineralocorticoid receptor antagonist that has shown to reduce albuminuria in type 2 diabetes (T2D) patients with chronic kidney disease (CKD) while revealing only a low risk of hyperkalemia. However, the effect of finerenone on CV and renal outcomes has not yet been investigated in long-term trials. Patients and Methods: The Finerenone in Reducing CV Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) trial aims to assess the efficacy and safety of finerenone compared to placebo at reducing clinically important CV and renal outcomes in T2D patients with CKD. FIGARO-DKD is a randomized, double-blind, placebo-controlled, parallel-group, event-driven trial running in 47 countries with an expected duration of approximately 6 years. FIGARO-DKD randomized 7,437 patients with an estimated glomerular filtration rate >= 25 mL/min/1.73 m(2) and albuminuria (urinary albumin-to-creatinine ratio >= 30 to <= 5,000 mg/g). The study has at least 90% power to detect a 20% reduction in the risk of the primary outcome (overall two-sided significance level alpha = 0.05), the composite of time to first occurrence of CV death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure. Conclusions: FIGARO-DKD will determine whether an optimally treated cohort of T2D patients with CKD at high risk of CV and renal events will experience cardiorenal benefits with the addition of finerenone to their treatment regimen. Trial Registration: EudraCT number: 2015-000950-39; ClinicalTrials.gov identifier: NCT02545049

The Simons Observatory: Gain, bandpass and polarization-angle calibration requirements for B-mode searches

We quantify the calibration requirements for systematic uncertainties for next-generation ground-based observatories targeting the large-angle B-mode polarization of the Cosmic Microwave Background, with a focus on the Simons Observatory (SO). We explore uncertainties on gain calibration, bandpass center frequencies, and polarization angles, including the frequency variation of the latter across the bandpass. We find that gain calibration and bandpass center frequencies must be known to percent levels or less to avoid biases on the tensor-to-scalar ratio r on the order of Δ r∼10-3, in line with previous findings. Polarization angles must be calibrated to the level of a few tenths of a degree, while their frequency variation between the edges of the band must be known to O(10) degrees. Given the tightness of these calibration requirements, we explore the level to which residual uncertainties on these systematics would affect the final constraints on r if included in the data model and marginalized over. We find that the additional parameter freedom does not degrade the final constraints on r significantly, broadening the error bar by O(10%) at most. We validate these results by reanalyzing the latest publicly available data from the collaboration within an extended parameter space covering both cosmological, foreground and systematic parameters. Finally, our results are discussed in light of the instrument design and calibration studies carried out within SO

Method for rapid performance validation of large TES bolometer array for POLARBEAR-2A using a coherent millimeter-wave source

International audiencePOLARBEAR-2A is the first receiver for the Simons Array cosmic microwave background polarization experiment. POLARBEAR-2A has transition-edge sensor bolometers on the focal plane. Signals from bolometers are multiplexed and read out by a single SQUID. The receiver was deployed in late 2018 in Atacama, Chile, and operation started in 2019, where rapid confirmation of correspondence between bolometers and multiplexed readout channels was important as an initial step of performance validation. For this purpose, we devised a method using a coherent source that allows us to identify the frequency band and polarization sensitivity angle for each readout channel without detailed bolometer tuning

Evidence for the Cross-correlation between Cosmic Microwave Background Polarization Lensing from Polarbear and Cosmic Shear from Subaru Hyper Suprime-Cam

We present the first measurement of cross-correlation between the lensing potential, reconstructed from cosmic microwave background (CMB) polarization data, and the cosmic shear field from galaxy shapes. This measurement is made using data from the Polarbear CMB experiment and the Subaru Hyper Suprime-Cam (HSC) survey. By analyzing an 11 deg2 overlapping region, we reject the null hypothesis at 3.5\u3c3 and constrain the amplitude of the cross-spectrum to , where is the amplitude normalized with respect to the Planck 2018 prediction, based on the flat \u39b cold dark matter cosmology. The first measurement of this cross-spectrum without relying on CMB temperature measurements is possible owing to the deep Polarbear map with a noise level of 3c6 \u3bcK arcmin, as well as the deep HSC data with a high galaxy number density of . We present a detailed study of the systematics budget to show that residual systematics in our results are negligibly small, which demonstrates the future potential of this cross-correlation technique

Improved polarization calibration of the BICEP3 CMB polarimeter at the South Pole

The BICEP3 Polarimeter is a small aperture, refracting telescope, dedicated to the observation of the Cosmic Microwave Background (CMB) at 95GHz. It is designed to target degree angular scale polarization patterns, in particular the very-much-sought-after primordial B-mode signal, which is a unique signature of cosmic inflation. The polarized signal from the sky is reconstructed by differencing co-localized, orthogonally polarized superconducting Transition Edge Sensor (TES) bolometers. In this work, we present absolute measurements of the polarization response of the detectors for more than approximately 800 functioning detector pairs of the BICEP3 experiment, out of a total of approximately 1000. We use a specifically designed Rotating Polarized Source (RPS) to measure the polarization response at multiple source and telescope boresight rotation angles, to fully map the response over 360 degrees. We present here polarization properties extracted from on-site calibration data taken in January 2022. A similar calibration campaign was performed in 2018, but we found that our constraint was dominated by systematics on the level of approximately 0.5° . After a number of improvements to the calibration set-up, we are now able to report a significantly lower level of systematic contamination. In the future, such precise measurements will be used to constrain physics beyond the standard cosmological model, namely cosmic birefringence

POLARBEAR-2: a new CMB polarization receiver system for the Simons array (Conference Presentation)

International audiencePOLARBEAR-2 is a new receiver system, which will be deployed on the Simons Array telescope platform, for the measurement of Cosmic Microwave Background (CMB) polarization. The science goals with POLARBEAR-2 are to characterize the B-mode signal both at degree and sub-degree angular-scales. The degree-scale polarization data can be used for quantitative studies on inflation, such as the reconstruction of the energy scale of inflation. The sub-degree polarization data is an excellent tracer of large-scale structure in the universe, and will lead to precise constraints on the sum of the neutrino masses. In order to achieve these goals, POLARBEAR-2 employs 7588 polarization-sensitive antenna-coupled transition-edge sensor (TES) bolometers on the focal plane cooled to 0.27K with a three-stage Helium sorption refrigerator, which is ~6 times larger array over the current receiver system. The large TES bolometer array is read-out by an upgraded digital frequency-domain multiplexing system capable of multiplexing 40 bolometers through a single superconducting quantum interference device (SQUID). The first POLARBEAR-2 receiver, POLARBEAR-2A is constructed and the end-to-end testing to evaluate the integrated performance of detector, readout, and optics system is being conducted in the laboratory with various types of test equipments. The POLARBEAR-2A is scheduled to be deployed in 2018 at the Atacama desert in Chile. To further increase measurement sensitivity, two more POLARBEAR-2 type receivers will be deployed soon after the deployment (Simons Array project). The Simons Array will cover four frequency bands at 95GHz, 150GHz, 220GH and 270GHz for better control of the foreground signal. The projected constraints on a tensor-to-scalar ratio (amplitude of inflationary B-mode signal) is σ(r=0.1) = $6.0 \times 10^{-3}$ after foreground removal ($4.0 \times 10^{-3}$ (stat.)), and the sensitivity to the sum of the neutrino masses when combined with DESI spectroscopic galaxy survey data is 40 meV at 1-sigma after foreground removal (19 meV(stat.)). We will present an overview of the design, assembly and status of the laboratory testing of the POLARBEAR-2A receiver system as well as the Simons Array project overview

Thermal testing for cryogenic CMB instrument optical design

Observations of the Cosmic Microwave Background rely on cryogenic instrumentation with cold detectors, readout, and optics providing the low noise performance and instrumental stability required to make more sensitive measurements. It is therefore critical to optimize all aspects of the cryogenic design to achieve the necessary performance, with low temperature components and acceptable system cooling requirements. In particular, we will focus on our use of thermal filters and cold optics, which reduce the thermal load passed along to the cryogenic stages. To test their performance, we have made a series of in situ measurements while integrating the third receiver for the BICEP Array telescope. In addition to characterizing the behavior of this receiver, these measurements continue to refine the models that are being used to inform design choices being made for future instruments