The VIMOS Ultra Deep Survey: the reversal of the star-formation rate - density relation at 2 < z < 5

Galaxie

An annotated list of ornamentals naturally found infected by Brevipalpus mite-transmitted viruses

The first cases of ornamental plants found infected by Brevipalpus transmitted viruses (BTV) were described in the 1990's from the region of Piracicaba, State of São Paulo, Brazil; subsequent cases were from other regions in the country and other American countries. Currently, 37 ornamental plant species (for the sake of simplicity, orchids being considered as a single species), belonging to 18 families of dicotyledons, have been reported hosting BTV. Because of the non systemic type of infection of these viruses, the localized diseases they cause are unimportant usually, but they have the potential to cause economic losses if severe outbreaks of Brevipalpus mite populations occur. Some ornamentals may serve as reservoirs to BTV known to cause serious damage to food crops as Citrus leprosis virus- cytoplasmic type (CiLV-C), passion fruit green spot virus (PFGSV) and Coffee ringspot virus (CoRSV).Os primeiros casos de plantas ornamentais encontradas naturalmente infetadas por vírus transmitidos por Brevipalpus (Acari: Tenuipalpidae) (VTB) foram registrados nos anos 1990 na região de Piracicaba, Estado de São Paulo, e ocorrências subseqüentes foram observadas em várias outras regiões do país e de outros países das Américas. Atualmente acham-se relatadas 37 espécies de ornamentais (para efeito de simplificação, orquídeas foram consideradas como única espécie) pertencentes a 18 famílias botânicas. Pelo fato de causarem apenas infecções localizadas, geralmente nas folhas, VTB em ornamentais não causam preocupações aos produtores, mas potencialmente podem causar perdas econômicas se ocorrerem explosões populacionais do ácaro vetor. Plantas ornamentais podem servir de reservatório de VTB de importância econômica como os vírus da leprose dos citros-tipo citoplasmático (CiLV-C), da mancha verde do maracujá (PFGSV) e da mancha anular do cafeeiro (CoRSV)

Euclid preparation: XXX. Performance assessment of the NISP red grism through spectroscopic simulations for the wide and deep surveys

This work focusses on the pilot run of a simulation campaign aimed at investigating the spectroscopic capabilities of the Euclid Near-Infrared Spectrometer and Photometer (NISP), in terms of continuum and emission line detection in the context of galaxy evolutionary studies. To this purpose, we constructed, emulated, and analysed the spectra of 4992 star-forming galaxies at 0.3 ≤ z ≤ 2.5 using the NISP pixel-level simulator. We built the spectral library starting from public multi-wavelength galaxy catalogues, with value-added information on spectral energy distribution (SED) fitting results, and stellar population templates from Bruzual & Charlot (2003, MNRAS, 344, 1000). Rest-frame optical and near-IR nebular emission lines were included using empirical and theoretical relations. Dust attenuation was treated using the Calzetti extinction law accounting for the differential attenuation in line-emitting regions with respect to the stellar continuum. The NISP simulator was configured including instrumental and astrophysical sources of noise such as the dark current, read-out noise, zodiacal background, and out-of-field stray light. In this preliminary study, we avoided contamination due to the overlap of the slitless spectra. For this purpose, we located the galaxies on a grid and simulated only the first order spectra. We inferred the 3.5σ NISP red grism spectroscopic detection limit of the continuum measured in the H band for star-forming galaxies with a median disk half-light radius of 0.″4 at magnitude H = 19.5 ± 0.2 AB mag for the Euclid Wide Survey and at H = 20.8 ± 0.6 AB mag for the Euclid Deep Survey. We found a very good agreement with the red grism emission line detection limit requirement for the Wide and Deep surveys. We characterised the effect of the galaxy shape on the detection capability of the red grism and highlighted the degradation of the quality of the extracted spectra as the disk size increased. In particular, we found that the extracted emission line signal-to-noise ratio (S/N) drops by ~45% when the disk size ranges from 0.″25 to 1″. These trends lead to a correlation between the emission line S/N and the stellar mass of the galaxy and we demonstrate the effect in a stacking analysis unveiling emission lines otherwise too faint to detect.Key words: surveys / Galaxy: evolution / galaxies: formation / galaxies: star formation / techniques: spectroscopic / instrumentation: detectors</p

Euclid Quick Data Release (Q1). Extending the quest for little red dots to z<4

Recent observations with the James Webb Space Telescope (JWST) have revealed an interesting population of sources with a compact morphology and a characteristic v-shaped continuum, namely blue at a rest frame łambda<4000,Å and red at longer wavelengths. The nature of these sources, which are called little red dots (LRDs), is still highly debated because it is unclear whether they host active galactic nuclei (AGNs) and their number seems to drop drastically at z<4. We took advantage of the $63,̊m covered by the quick Euclid Quick Data Release (Q1) to extend the search for LRDs to brighter magnitudes and lower redshifts than what was possible with JWST. This is fundamental for a broader view of the evolution of this peculiar galaxy population. The selection was performed by fitting the available photometric data (Euclid, the Spitzer Infrared Array Camera (IRAC), and ground-based griz data) with two power laws to retrieve the rest-frame optical and UV slopes consistently over a wide redshift range (i.e. z<7.6). We then excluded extended objects and possible line emitters and inspected the data visually to remove any imaging artefacts. The final selection included 3341 LRD candidates from z=0.33 to z=3.6, 29 of which were also detected in IRAC. The resulting rest-frame UV luminosity function, in contrast with previous JWST studies, shows that the number density of LRD candidates increases from high redshift to z=1.5--$2.5$ and decreases at even lower redshifts. The subsample of more robust LRD candidates that are also detected with IRAC show a weaker evolution, however, which is affected by low statistics and limited by the IRAC resolution. The comparison with previous quasar UV luminosity functions shows that LRDs are not the dominant AGN population at z<4 and M_ ̊m UV <-21. Follow-up studies of these LRD candidates are pivotal to confirm their nature, probe their physical properties, and determine whether they are compatible with JWST sources because the different spatial resolution and wavelength coverage of Euclid and JWST might select different samples of compact sources

Genomic heterogeneity of hepatitis B virus (HBV) and outcome of perinatal HBV infection

BACKGROUND/AIMS: Data regarding hepatitis B virus (HBV) genomic heterogeneity in perinatal infection are incomplete, although HBV variants might be involved in neonatal fulminant hepatitis (ALF). We investigated HBV variability in infected babies showing different clinical courses. METHODS: We analyzed HBV genomes isolated from nine vertically infected babies and the mothers of four of them. Two infants born to HBe-antigen (HBeAg)-positive women developed a chronic infection; seven babies (six born to anti-HBe mothers) developed acute hepatitis that had a fulminant course in four cases and a benign course in three. Two babies developing ALF received anti-HBV immunoprophylaxis at birth. RESULTS: Viruses carrying no significant mutation infected infants born to HBeAg-positive women. HBeAg-defective viruses were detected both in children with benign and fulminant hepatitis and their mothers. A double nucleotide mutation at positions 1762 and 1764 of the HBV core-promoter was found in two of the four infants with ALF, although it was not detected in isolates from the mother of one of them. No significant S gene mutation was found in HBV from any of the babies. CONCLUSIONS: This study indicates that HBV genomic heterogeneity is not primarily involved either in the evolution of the infection or the failure of neonatal HBV immunoprophylaxis

A long-term controlled drug-delivery with anionic beta cyclodextrin complex in layer-by-layer coating for percutaneous implants devices

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A long-term controlled drug-delivery with anionic beta cyclodextrin complex in layer-by-layer coating for percutaneous implants devices

This study demonstrated a drug-delivery system with anionic beta cyclodextrin (β-CD) complexes to retain tetracycline (TC) and control its release from multilayers of poly(acrylic acid) (PAA) and poly(l-lysine) (PLL) in a ten double layers ([PAA/PLL]10) coating onto titanium. The drug-delivery capacity of the multilayer system was proven by controlled drug release over 15 days and sustained released over 30 days. Qualitative images confirmed TC retention within the layer-by-layer (LbL) over 30 days of incubation. Antibacterial activity of TC/anionic β-CD released from the LbL was established against Staphylococcus aureus species. Remarkably, [PAA/PLL]10/TC/anionic β-CD antibacterial effect was sustained even after 30 days of incubation. The non-cytotoxic effect of the multilayer system revealed normal human gingival fibroblast growth. It is expected that this novel approach and the chemical concept to improve drug incorporation into the multilayer system will open up possibilities to make the drug release system more applicable to implantable percutaneous devices.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Dental Materials and Prosthodontics School of Dentistry at Araraquara São Paulo State University (UNESP), Humaita, 1680 AraraquaraRegenerative Biomaterials Radboudumc, Philips Van Leydenlaan 25Department of Physical Chemistry Institute of Chemistry São Paulo State University (UNESP)Department of Prosthodontics and Periodontology Piracicaba Dental School University of Campinas (UNICAMP), Av. Limeira, 901Department of Tumor Immunology Radboudumc and Radboud Institute for Molecular Life Sciences (RIMLS), Geert Grooteplein Zuid, 28 NijmegenDepartment of Physiology and Pathology School of Dentistry at Araraquara São Paulo State University (UNESP)Department of Dental Materials and Prosthodontics School of Dentistry at Araraquara São Paulo State University (UNESP), Humaita, 1680 AraraquaraDepartment of Physical Chemistry Institute of Chemistry São Paulo State University (UNESP)Department of Physiology and Pathology School of Dentistry at Araraquara São Paulo State University (UNESP)FAPESP: 2015/03567-7FAPESP: 2018/19345-