Propiedades psicométricas de la escala de habilidades sociales en adolescentes y jóvenes infractores de Trujillo y Lima

Se buscó obtener las propiedades psicométricas, de la escala de habilidades sociales de Gismero. El tipo de investigación empleado fue tecnológico y el diseño instrumental, la población estuvo conformada por 985, pertenecientes a un centro juvenil de diagnóstico y rehabilitación, de la ciudad de Trujillo y Lima, cuyas edades oscilan de 14 a 22 años; la población y la muestra estuvieron conformadas por 683 participantes. Los resultados de la validez de contenido (n=10) apreciándose una relación estadísticamente significativa (p<.05) evidenciando que los ítems presentan claridad, coherencia y en relevancia; el análisis factorial confirmatorio, evidenció la presencia de un solo factor, conformado 11 ítems, con cargas factorial que oscilan de .33 a .54 y una correlación múltiple al cuadrado de .11 a .29. La confiabilidad fue obtenida a partir del análisis, Omega de McDonald, presentando un alfa de.713; como último objetivo se realizaron las normas generales percentilares y puntuaciones típicas tipo S

Fabrication of well-ordered silicon nanopillars embedded in a microchannel : Via metal-assisted chemical etching: A route towards an opto-mechanical biosensor

Ordered nanopillars have been used as a smart configuration to design and fabricate localized surface plasmon resonance (LSPR) sensors. Importantly, these nanostructures can be integrated within microfluidic channels as a novel opportunity to enhance the response of biosensors and also to control the fluid flow by modifying the wettability surface of the walls. In this work, we demonstrate a large-scale and low-cost nanofabrication methodology that integrates the fabrication of silicon nanopillars (SiNPs) inside a microfluidic channel. The strategy is based on placing a catalytic gold layer patterned with nanoholes inside a SU-8 microchannel, by combining nanosphere lithography, reactive ion etching, and e-beam gold deposition, to control the area, separation distance and diameter of the nanostructures. The height of the SiNPs strongly depends on a well-controlled metal-assisted silicon etching protocol. We demonstrate experimentally that the design and the cleaning of the catalytic gold mesh using ultraviolet ozone strongly affect the etching rate for the formation of large-surface-area nanopillars. Our results explain the fast fabrication of hexagonal arrays of SiNPs embedded in a microfluidic channel with varying aspect ratio from 2 to 7 and separation of 300 nm and 400 nm, respectively, which has important implications for the achievement of new optomechanical biosensors

Changes in the arrhythmic profile of patients treated for heart failure are associated with modifications in their myocardial perfusion conditions

Background: Heart failure (HF) patients can benefit from a proper RS. We had observed that they show an increase in the number of arrhythmias during the first year of pharmacological treatment. Methods: We carried out a prospective observational study in which patients in an HF Clinic were included when they had follow-up Holter monitoring. Patients also had a baseline myocardial perfusion scan (Tc99 sestaMIBI/dypiridamole) and a control scan. Results: We included 90 patients with follow-up Holter and 35 with scintigraphy, for analysis. Fifty-six (62.2%) were men and the average age was 60.8 &#177; 14.6 years. Follow-up periods were divided by six-month intervals up to 18 months or more, an increase in premature ventricular contractions (PVCs) occurred in the six-month to one-year period (1915.4 &#177; &#177; 4686.9 vs. 2959 &#177; 6248.1, p = 0.09). In the one-year to 18-month control, PVCs went from 781.6 &#177; 1082.4 to 146.9 &#177; 184.1, p = 0.05. The increase in PVCs correlated with a reduction in scintigraphy-detected ischemic territories, 5.64 &#177; 5.9 vs. 3.18 &#177; 3 (p = 0.1) and a gain in those showing a reverse redistribution pattern (0.18 &#177; 0.6 vs. 2.09 &#177; 4.01, p = 0.1). Necrotic territories and time domain heart rate variability did not show significant changes. Conclusions: PVCs increase during the first year of HF treatment, and then they tend to diminish and stabilize. These changes seem to correlate with changes in the perfusion state of the patient. While ischemic territories decrease, reverse redistribution increases, showing that endothelial dysfunction could have a relevant role in arrhythmia generation, possibly because of membrane instability of recovered hibernating myocardium. (Cardiol J 2008; 15: 261-267

The effect of left ventricular dysfunction on right ventricle ejection fraction during exercise in heart failure patients: Implications in functional capacity and blood pressure response

Background: The aim of this study was to assess the effect of left ventricular dysfunction on right ventricular ejection fraction during exercise in heart failure patients and its implications in functional capacity and blood pressure response. Methods: In a cross-sectional study 65 patients with heart failure were included. Left and right ventricular ejection fractions were evaluated by radio-isotopic ventriculography. All subjects underwent an exercise treadmill test (Bruce modified protocol). Systolic and diastolic blood pressures were also recorded. Results: From the total population, 38 (58.46%) showed a significant increase (&#8805; 5%) in left ventricular ejection fraction (LVEF) and 27 (41.5%) showed a significant decrease in LVEF (&#8805; 5%) after the stress test. Patients with a significant reduction in LVEF during stress had lower exercise tolerance (4.1 &#177; 2.5 vs. 6.1 &#177; 2.5 METs, p = 0.009) compared to those who showed an increase in LVEF. Diastolic blood pressure was higher at rest among those who had a reduced LVEF during stress (83 &#177; 12.2 vs. 72.6 &#177; 12.2 mm Hg, p = 0.035) and during exercise (95 &#177; 31.3 vs. 76.9 &#177; 31.3 mm Hg, p = 0.057), as well as mean arterial pressure in the same group (97.1 &#177; 11.6 mm Hg, p = 0.05). In addition, this group decrease of &#8211;8.8 &#177; 51.6% in the right ventricular ejection fraction after exercise compared to an increase of 27.3 &#177; &#177; 49.1% (p = 0.007) among the patients with an increase in LVEF. Conclusions: Biventricular systolic dysfunction during exercise is associated with higher rest and stress blood pressure and worse functional capacity

Reversible changes of electrocardiographic abnormalities after parathyroidectomy in patients with primary hyperparathyroidism

Background: Several studies have reported that primary hyperparathyroidism is a risk factor of higher cardiovascular mortality, mainly because hyperparathyroidism is related to arterial hypertension, arrhythmias, structural heart abnormalities and activation of the renin&#8211;angiotensin&#8211; aldosterone system. However, very few studies have shown the electrocardiographic changes that occur after parathyroidectomy. That was the aim of this study. Methods: We studied 57 consecutive patients with primary hyperparathyroidism surgically treated. Electrocardiogram, serum electrolytes, parathyroid hormone, creatinine and albumin measures were obtained before and after surgery and were compared. Results: The most common basal electrocardiographic abnormalities were left ventricular hypertrophy (LVH, 24.6%), conduction disturbances (16.3%), and short QT and QTc intervals. After surgery, a QTc interval lengthening and a tendency of T wave shortening were observed, as well as an inverse association between QTc interval and serum levels of magnesium and corrected calcium. There were no differences in LVH and conduction disturbances after surgery. Conclusions: Primary hyperparathyroidism is an important factor in the development of electrocardiographic abnormalities in this population, some of which are not corrected after parathyroidectomy. Further studies are required to demonstrate what factors are associated with persistence of electrocardiographic disturbances after surgery

Estudio de mercado para la comercialización de los productos agrícolas, avícolas y ganaderos para el desarrollo local del cantón Santo Domingo, provincia de Santo Domingo de los Tsáchilas.

Esta investigación relacionada con el estudio de mercado para la comercialización de los productos agrícolas, avícolas y ganaderos para el desarrollo local del cantón Santo Domingo, provincia de Santo Domingo de los Tsachilas plante como problema ¿Que incidencia tendría un estudio de mercado para la comercialización de los productos agrícolas, avícolas y ganaderos para el desarrollo local del cantón Santo Domingo?, cuyo objetivo general es elaborar un estudio de mercado para la comercialización de los productos agrícolas, avícolas y ganaderos para el desarrollo del cantón de Santo Domingo; el mismo que para su ejecución fue necesario la utilización de métodos estratégicos y/o técnicas como la encuesta, entrevista, el análisis, arrojan como resultado del diagnóstico el Plan para la implementación de una granja integral para desarrollar un ciclo óptimo de producción agrícola, avícola y ganadera del cantón Santo Domingo, para el desarrollo local&nbsp; y mejorar la productividad y calidad de vida de productores

Building of a flexible microfluidic plasmo-nanomechanical biosensor for live cell analysis

Biosensor devices can constitute an advanced tool for monitoring and study complex dynamic biological processes, as for example cellular adhesion. Cellular adhesion is a multipart process with crucial implications in physiology (i.e. immune response, tissue nature, architecture maintenance, or behaviour and expansion of tumor cells). This work focuses on offering a controlled methodology in order to fabricate a flexible plasmo-nanomechanical biosensor placed within a microfluidic channel as a new tool for future cell adhesion studies. We designed, fabricated, and optically and mechanically characterized this novel optical biosensor. As a proof-of-concept of its functionality, the biosensor was employed to observe fibroblasts adhesion in a cell culture. The device is configured by an hexagonal array of flexible rigid/soft polymeric nanopillars capped with plasmonic gold nanodisks integrated inside a microfluidic channel. The fabrication employs low-cost and large-scale replica molding techniques using two different polymers materials (EPOTECK OG142 and 310 M). By using those materials the spring constant of the polymer nanopillars (k) can be fabricated from 1.19E-02 [N/m] to 5.35E+00 [N/m] indicating different mechanical sensitivities to shear stress. Therefore, the biosensor has the feasibility to mimic soft and rigid tissues important for the description of cellular nanoscale behaviours. The biosensor exhibits a suitable bulk sensitivity of 164 nm or 206 nm/refractive index unit respectively, depending on the base material. The range of calculated forces goes from ≈1.98 nN to ≈.942 μN. This supports that the plasmo-nanomechanical biosensors could be employed as novel tool to study living cells behavior

Plan de reducción de pérdidas de energía de la Corporación Nacional de Electricidad Regional Santo Domingo (CNEL), en la provincia de Santo Domingo de los Tsáchilas.

Este trabajo de investigación se enfoca, en el plan de reducción de pérdidas de energía de la Corporación Nacional de Electricidad CNEL, de la provincia de Santo Domingo de los Tsáchilas promoviendo una campaña de concientización ciudadana para evitar el hurto de este servicio. Durante el periodo de abril (Domingo, 2012) se indagó en los sectores de los barrios bajos de Santo Domingo el problema el cual tiene la otra cara de la moneda, pues existen innumerables asentamientos que carecen de servicios básicos como el de la energía eléctrica. En estas zonas los abonados se conectan directamente de la red para tomar energía eléctrica, sin que este problema existente desde hace años haya podido ser atenuado con eficiencia y difícilmente podrían ser eliminadas por completo. Así se detecta un problema de incremento de las pérdidas de energía en la corporación Nacional de electricidad CNEL Santo Domingo debido a la falta de equipos de medición, equipos obsoletos o en mal estado, así como redes desnudas que dan pasó a las conexiones directas. El plan propuesto para la recuperación de las pérdidas no técnicas del sistema CNEL Santo Domingo estima reducir las pérdidas en un lapso no superior a un año, para así lograr incrementar el flujo de caja que proporcione sustentabilidad financiera y permita el pago de los valores facturados por generadores y transmisor, así como lograr su objetivo principal: Disminuir las pérdidas que se han venido dando durante años, para lo cual se deberá emplear personal técnico capacitado y los materiales que cumplan con las normas de calidad especificadas. Por tal virtud se recomienda una actualización permanente de su base de datos, con el fin de disponer de información precisa y confiable para el análisis de pérdida en el sistema de comercialización, para de esta forma concientizar al cliente con el fin de optimizar el uso de energía eléctrica y con esto eliminar el fraude mediante la aplicación de todos los mecanismos necesarios

Tailored height gradients in vertical nanowire arrays via mechanical and electronic modulation of metal-assisted chemical etching

In current top-down nanofabrication methodologies the design freedom is generally constrained to the two lateral dimensions, and is only limited by the resolution of the employed nanolithographic technique. However, nanostructure height, which relies on certain mask-dependent material deposition or etching techniques, is usually uniform, and on-chip variation of this parameter is difficult and generally limited to very simple patterns. Herein, a novel nanofabrication methodology is presented, which enables the generation of high aspect-ratio nanostructure arrays with height gradients in arbitrary directions by a single and fast etching process. Based on metal-assisted chemical etching using a catalytic gold layer perforated with nanoholes, it is demonstrated how nanostructure arrays with directional height gradients can be accurately tailored by: (i) the control of the mass transport through the nanohole array, (ii) the mechanical properties of the perforated metal layer, and (iii) the conductive coupling to the surrounding gold film to accelerate the local electrochemical etching process. The proposed technique, enabling 20-fold on-chip variation of nanostructure height in a spatial range of a few micrometers, offers a new tool for the creation of novel types of nano-assemblies and metamaterials with interesting technological applications in fields such as nanophotonics, nanophononics, microfluidics or biomechanics. Based on metal-assisted chemical etching using a catalytic gold layer perforated with nanoholes, it is demonstrated how high aspect-ratio nanostructure arrays with directional height gradients can be accurately tailored by: i) control of mass transport through the nanohole array, ii) mechanical properties of the perforated metal layer, and iii) conductive coupling to the surrounding gold film to accelerate the local electrochemical etching process. The proposed technique, enabling 20-­-fold on-­-chip variation of nanostructure height in a spatial range of a few microns, offers a new tool for the creation of novel types of nano-­-assemblies and metamaterials with interesting technological applications in fields such as nanophotonics, nanophononics, microfluidics or biomechanics

Correlation Analysis of People Attitude and the Development of Chemical Processes in the Human Body

This chemical science investigation was made to efficiently understand the way in which ionic substances operate in the human body and its correlation that they can have with the attitude of people, whose evaluation was carried out according to the analysis of three actions developed in the human body, such as digestion factors, family, work and social relationships (emotional actions) and the health of 10 people surveyed in the city of Tijuana, Baja California. This evaluation had a main hypothesis at the beginning of the investigation, indicating that, of the three factors mentioned, the one that links emotions had the greatest effect on the behavior of the people evaluated, with the aspect of family and work relationships being of primary importance; followed by the health factor and finally the digestion factor. This scientific study included an analysis of three principal aspects, being first the daily food as a nutrition action, followed a chemical analysis of ionic substances of the human body of the 10 persons evaluated. In addition, the third aspect evaluated was the emotional state of the people and a clinic with the urine analysis were considered to indicate the pH, temperature and oxygen level of each person, with which the main chemical elements of the ionic substances that can circulate through the human body were obtained, as part of the food intake. and drinks, emotional factor and digestion. This scientific study was made from March to May of 2023