457 research outputs found

    Developments in multivariate post quantum cryptography.

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    Ever since Shor\u27s algorithm was introduced in 1994, cryptographers have been working to develop cryptosystems that can resist known quantum computer attacks. This push for quantum attack resistant schemes is known as post quantum cryptography. Specifically, my contributions to post quantum cryptography has been to the family of schemes known as Multivariate Public Key Cryptography (MPKC), which is a very attractive candidate for digital signature standardization in the post quantum collective for a wide variety of applications. In this document I will be providing all necessary background to fully understand MPKC and post quantum cryptography as a whole. Then, I will walk through the contributions I provided in my publications relating to differential security proofs for HFEv and HFEv−, key recovery attack for all parameters of HFEm, and my newly proposed multivariate encryption scheme, HFERP

    Optimization of Surface Roughness of D2 Steels in WEDM using ANN Technique

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    Attempt has been made to investigate the experimental process and surface roughness (SR) optimization of cold working (high carbon and high chromium) hard die steel (D2) during wire electrical discharge machining processes (WEDM). It is very difficult to determine optimal cutting parameters for improving cutting performance has been reported. Wire electrical discharge machining process relies heavily on the operators’ technologies and experience because of their numerous and diverse range as using complicated cuts can made through difficult to machine electrically conductive components, WEDM process was developed to generate precise cutting on complicate, hard and difficult to machine materials. Tan-sigmoid and purlin transfer functional with bias based four layered back propagation artificial neural network (BPANN) approach have been used to investigate the effect of six independent parameters namely gap voltage (Vg), flush rate (Fr), Pulse on time (Ton), pulse off time (Toff), wire feed (Wf) and wire tension (Wt) over CLA value of surface roughness (Ra) along with corresponding material removal rate (MRR). A fractional factorial design of experiment of three level were employed to conduct 80 rows of experiment on (D2) steel with chrome coated copper alloy wire electrode. The predicted response, CLA values of SR and corresponding MRR were observed by the approach of BPANN from experimental (55 rows for training, 15 rows for validation and 10 for testing) data. Software instructed programme has been used individually for training, validation and testing in MATLAB 2010a to find the corresponding prediction output. Two fold cross over technique (TFCT) were used to developed distinguish (S1 and S2) models and also developed more models depending on numbers of neurons used in primary and secondary hidden layers. The model adequacy is very satisfactory as correlation coefficient (R2) is found to be 99.1% and adjusted (Radj.2) statistics is 98.5. It is found those spark time ON/OFF, wire feed rate, wire tension, gap voltage and flush rate and few of their interactions have significant effect on SR

    Results of the Mitrofanoff procedure in urinary tract reconstruction in children

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90139/1/j.1464-410X.1997.33724.x.pd

    Zika virus impairs the development of blood vessels in a mouse model of congenital infection

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    Zika virus (ZIKV) is associated with brain development abnormalities such as primary microcephaly, a severe reduction in brain growth. Here we demonstrated in vivo the impact of congenital ZIKV infection in blood vessel development, a crucial step in organogenesis. ZIKV was injected intravenously in the pregnant type 2 interferon (IFN)-deficient mouse at embryonic day (E) 12.5. The embryos were collected at E15.5 and postnatal day (P)2. Immunohistochemistry for cortical progenitors and neuronal markers at E15.5 showed the reduction of both populations as a result of ZIKV infection. Using confocal 3D imaging, we found that ZIKV infected brain sections displayed a reduction in the vasculature density and vessel branching compared to mocks at E15.5; altogether, cortical vessels presented a comparatively immature pattern in the infected tissue. These impaired vascular patterns were also apparent in the placenta and retina. Moreover, proteomic analysis has shown that angiogenesis proteins are deregulated in the infected brains compared to controls. At P2, the cortical size and brain weight were reduced in comparison to mock-infected animals. In sum, our results indicate that ZIKV impairs angiogenesis in addition to neurogenesis during development. The vasculature defects represent a limitation for general brain growth but also could regulate neurogenesis directly

    An Insight into Biofunctional Curcumin/Gelatin Nanofibers

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    Electrospinning (ESPNG) was used to synthesize ultrathin (UT) and uniform nanofibers (from 5 nm to a few hundred nanometers) of various materials which have biomedical applications (BAs) such as dressing of wounds, drug discharge, and so on and so forth. In the first half of the report, there is an audit on the nanofibers having low diameter so that it could have larger surface area to volume proportion, likewise with that it would have sufficient porosity and improved mechanical properties required for wound healing. Nanofibrous mats (NMs) with high biocompatibility could be utilized during healing of wounds by sustained release of curcumin (Cc) and oxygen. The ESPNG was understood through in-depth numerical investigation in the present report. Furthermore, the process parameters (PMs) were reviewed in depth for their contributions in synthesizing UT - Curcumin/Gelatin (Cc/G) nanofibers (NFs) of optimum diameter. The aim of the discussion was to demonstrate that simply optimizing biofunctional (BF) - Cc/G NFs might not be enough to satisfy experts until they are also given access details about the complete ESPNG method (mathematical mechanism) to improve hold over the synthesis of NMs (suitable for BAs) for the release profile of Cc throughout critical periods of healing process

    Gliomatosis cerebri presenting as rapidly progressive dementia and parkinsonism in an elderly woman: a case report

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    <p>Abstract</p> <p>Introduction</p> <p>Dementia is one of the most important neurological disorders in the elderly. Dementia of tumoral origin is rare and parkinsonism of neoplastic origin is unusual. We herein report a case of gliomatosis cerebri, a very rare brain tumor seldom affecting the elderly, which presented as rapidly progressive dementia and parkinsonism.</p> <p>Case presentation</p> <p>An 82-year-old woman very rapidly developed progressive dementia and akineto-rigid parkinsonism. Brain CT scan was normal. Cerebral magnetic resonance imaging (MRI) with gadolinium injection highlighted a diffuse tumor-related infiltration involving both lobes, the putamen, the pallidum, the substantia nigra, and the brainstem, corresponding to the specific description and definition of gliomatosis cerebri.</p> <p>Conclusion</p> <p>This atypical presentation of a gliomatosis cerebri, and the infiltration of the substantia nigra by the tumor, merits attention.</p
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