A Light Calibration System for the ProtoDUNE-DP Detector

A LED-based fiber calibration system for the ProtoDUNE-Dual Phase (DP) photon detection system (PDS) has been designed and validated. ProtoDUNE-DP is a 6x6x6 m3 liquid argon time-projection-chamber currently being installed at the Neutrino Platform at CERN. The PDS is based on 36 8-inch photomultiplier tubes (PMTs) and will allow triggering on cosmic rays. The system serves as prototype for the PDS of the final DUNE DP far detector in which the PDS also has the function to allow the 3D event reconstruction on non-beam physics. For this purpose an equalized PMT response is desirable to allow using the same threshold definition for all PMT groups, simplifying the determination of the trigger efficiency. The light calibration system described in this paper is developed to provide this and to monitor the PMT performance in-situ.Comment: 15 pages, 5 figure

Biogas production from the specialized dairy farming and porcine subsectors in Antioquia, Colombia: theoretical and technical-energy potential approach

Received: February 23rd, 2022 ; Accepted: May 1st, 2022 ; Published: May 11th, 2022 ; Correspondence: [email protected] developing countries, residual biomass usage by means of anaerobic digestion offers several benefits and opportunities, such as a sustainable energy source, production of organic fertilizers and new agrobusiness models. In Latin America, Colombia is one of the most promising markets for the implementation of this technology in terms of availability of biomass and economic growth, as recently reported by local government organizations. In this paper, special attention is given to Antioquia, a department of Colombia with the largest farms of cattle and pigs, according to information reported in 2018 by the Ministry of Agriculture and Rural Development. It is estimated that manure from the porcine subsector in Antioquia has an approximate technical-energy potential of 1,896 TJ year-1 , varying from 1,611 to 2,186 TJ year-1 , corresponding to the 95% confidence interval. In the case of manure generated by the livestock subsector in Antioquia, it is estimated a theoretical energy potential of 8,566 TJ year-1 . However, traditional extensive production systems disseminate manure through the pastures turning centralization of the available residual biomass a difficult task and not senseful. Based on the local practices of the specialized dairy subsector, it is estimated that manure collected during the milking process could reached up to 25% of the total available. Biochemical conversion of this amount of biomass has an estimated technical-energy potential of 187 TJ year-1 , varying from 156 and 236 TJ year-1 , corresponding to the 95% confidence. The aim of this article is to estimate the technical-energy potential for the livestock and porcine subsectors in the Department of Antioquia, based on the available residual biomass according to local farming practices

A new perspective on Copper Age technology, economy and settlement: grinding tools at the Valencina mega‑site

Activity patterns at large prehistoric sites are often difficult to interpret, as they frequently combine productive, domestic and funerary components. Valencina, the largest of the Copper Age mega-sites in Iberia, has proved particularly challenging in this regard. Macrolithic tool assemblages have been generally neglected in these debates but can provide specific insight into the nature and patterning of activities. In this study, 185 grinding tools from seven separate excavations across this 450 ha mega-site were subjected to multiple lines of analysis including quantification, morphology, raw material, use-wear and depositional context. A surprising feature of this assemblage is the high degree of fragmentation, with more than half of the items representing less than 25% of the original artefact and only a small minority of them (< 10%) complete. The absence of intact quernstones is particularly striking. The results indicate a ritualization of deposition at Valencina, and throw new light on the interpretation of this complex site. Furthermore, they emphasize the central role that grinding technology should play in future discussion of European prehistoric mega-sites

CARACTERIZACIÓN SISMOTECTÓNICA REGIONAL PRELIMINAR DE UN SECTOR DEL PIEDEMONTE LLANERO COLOMBIANO: CORREDOR SAN JUAN DE ARAMA – CUMARAL,META

&nbsp; With the regional tectonic scenario determination carried out with remote sensors, secondary information and field observations, be determined that the faults related to the Eastern Frontal Fault System - EFFS, obeys to a geometry of shortcut planes with maximum longitudes of 30 km, these represent thrust faults that limit to the Andean basement with the South American plate. Also with the support of the historical seismicity and instrumental seismicity registration of the RSNC for the period 1993 - 2001, low seismic activity was determined between 3º and 4º N, and moderate seismic activity to the south of this latitude. This sector of EFFS is composed by listric fault type with low dip angle toward depth under compression stress regime and it seismicity obeys to stress release of these planes in the contact area where the basements converge. The maximum magnitude estimated is M ≥ 6,0 with 5 - 30 km depth hypocenters. However the low previous seismological information and few studies in these faults yet hinder the realization of earthquake prediction in probabilistic sense for these. &nbsp; Key Words: Andean Eastern Cordillera Foothill, Eastern Frontal Fault System, Geotectonics, Seismicity, Seismotectonics &nbsp;&nbsp; Con la determinación del escenario tectónico regional realizado con sensores remotos, información secundaria y observaciones de campo, se ha encontrado que las fallas relacionadas al Sistema de Fallas de la Falla Frontal de la Cordillera Oriental &nbsp; - SFFFCO, obedecen a una geometría de planos muy seccionados con longitudes máximas de 30 km que representan fallas de cabalgamiento que limitan al basamento Andino con la placa suramericana. Con el apoyo de la sismicidad histórica y del registro instrumental de la RSNC para el período 1993 - 2001, se determinó igualmente poca actividad sísmica entre los 3º y 4º N, y una actividad moderada al sur de esta latitud. Este sector del SFFFCO se caracteriza por presentar planos de tipo lístrico bajo régimen compresivo cuyo buzamiento decrece en ángulo hacía profundidad y la sismicidad obedece a la liberación de esfuerzos de estos planos en la zona de contacto donde convergen los basamentos. La magnitud máxima posible esperada es M ≥ 6,0, con hipocentros que oscilan entre 5 y 30 km Sin embargo la baja información sismológica y los pocos estudios realizados en estas fallas todavía impiden realizar la estimación en el sentido probabilístico de los periodos intersísmicos en estas. &nbsp; Palabras Clave: Piedemonte Llanero colombiano, Sistema de Fallas de la Falla Frontal de de la Cordillera Oriental, Geotectónica, &nbsp;Sismicidad, Sismotectónica. &nbsp; &nbsp; &nbsp

CARACTERIZACIÓN SISMOTECTÓNICA REGIONAL PRELIMINAR DE UN SECTOR DEL PIEDEMONTE LLANERO COLOMBIANO: CORREDOR SAN JUAN DE ARAMA – CUMARAL,META

&nbsp; With the regional tectonic scenario determination carried out with remote sensors, secondary information and field observations, be determined that the faults related to the Eastern Frontal Fault System - EFFS, obeys to a geometry of shortcut planes with maximum longitudes of 30 km, these represent thrust faults that limit to the Andean basement with the South American plate. Also with the support of the historical seismicity and instrumental seismicity registration of the RSNC for the period 1993 - 2001, low seismic activity was determined between 3º and 4º N, and moderate seismic activity to the south of this latitude. This sector of EFFS is composed by listric fault type with low dip angle toward depth under compression stress regime and it seismicity obeys to stress release of these planes in the contact area where the basements converge. The maximum magnitude estimated is M ≥ 6,0 with 5 - 30 km depth hypocenters. However the low previous seismological information and few studies in these faults yet hinder the realization of earthquake prediction in probabilistic sense for these. &nbsp; Key Words: Andean Eastern Cordillera Foothill, Eastern Frontal Fault System, Geotectonics, Seismicity, Seismotectonics &nbsp;&nbsp; Con la determinación del escenario tectónico regional realizado con sensores remotos, información secundaria y observaciones de campo, se ha encontrado que las fallas relacionadas al Sistema de Fallas de la Falla Frontal de la Cordillera Oriental &nbsp; - SFFFCO, obedecen a una geometría de planos muy seccionados con longitudes máximas de 30 km que representan fallas de cabalgamiento que limitan al basamento Andino con la placa suramericana. Con el apoyo de la sismicidad histórica y del registro instrumental de la RSNC para el período 1993 - 2001, se determinó igualmente poca actividad sísmica entre los 3º y 4º N, y una actividad moderada al sur de esta latitud. Este sector del SFFFCO se caracteriza por presentar planos de tipo lístrico bajo régimen compresivo cuyo buzamiento decrece en ángulo hacía profundidad y la sismicidad obedece a la liberación de esfuerzos de estos planos en la zona de contacto donde convergen los basamentos. La magnitud máxima posible esperada es M ≥ 6,0, con hipocentros que oscilan entre 5 y 30 km Sin embargo la baja información sismológica y los pocos estudios realizados en estas fallas todavía impiden realizar la estimación en el sentido probabilístico de los periodos intersísmicos en estas. &nbsp; Palabras Clave: Piedemonte Llanero colombiano, Sistema de Fallas de la Falla Frontal de de la Cordillera Oriental, Geotectónica, &nbsp;Sismicidad, Sismotectónica. &nbsp; &nbsp; &nbsp

Síndrome neuroléptico maligno inducido por risperidona y facilitado por sepsis de origen urinario: clínica y fisiopatología.

Risperidone is a selective monoaminergic antagonist with a high affinity for dopamine receptors that can cause neuroleptic malignant syndrome (NMS), considered a life-threatening medical emergency. It has an incidence of up to 3% and its mortality is between 10 and 20%. The case of a 56-year-old female who met the clinical criteria of NMS, induced by the use of risperidone and facilitated by a sepsis of urinary origin, is reported. It was managed with a dopamine agonist and the change of antipsychotic, which resulted in a favorable clinical course. The NMS is a low-prevalence entity whose diagnosis has specificity and sensitivity greater than 90%, reason for which must be clearly differentiated from other pathologies. The mechanism by which urinary infection could facilitate the occurrence of this disease is discussed. Early diagnosis improves the response to an adequate management to be established in each case.La risperidona es un antagonista selectivo monoaminérgico, con una elevada afinidad por receptores dopaminérgicos, que puede producir síndrome neuroléptico maligno (SNM), considerado una emergencia médica con alto riesgo de muerte. Tiene una incidencia de hasta el 3% y su mortalidad está entre el 10 y 20%. Se reporta el caso de una paciente de 56 años, que reunía los criterios clínicos del SNM, inducido por el uso de risperidona y facilitado por una sepsis de origen urinario. El tratamiento se condujo con un agente agonista dopaminérgico y cambio del antipsicótico, procedimientos que resultaron en una adecuada evolución clínica. El SNM es una entidad de baja prevalencia, para la cual existen criterios diagnósticos con especificidad y sensibilidad mayor del 90%, por lo que debe diferenciarse claramente de otras patologías. Se discute el mecanismo mediante el cual la infección urinaria facilitaría la ocurrencia de esta enfermedad. El diagnóstico precoz mejora la respuesta al manejo adecuado que se establezca en cada caso

MEGADES: MEGARA Galaxy Discs Evolution Survey. Data Release I: central fields

The main interest of the Science Team for the exploitation of the MEGARA instrument at the 10.4m Gran Telescopio Canarias (GTC hereafter) is devoted to the study of nearby galaxies, with focus on the research of the history of star formation, and chemical and kinematical properties of disc systems. We refer to this project as MEGADES: MEGARA Galaxy Discs Evolution Survey. The initial goal of MEGADES is to provide a detailed study of the inner regions of nearby disc galaxies, both in terms of their spectrophotometric and chemical evolution, and their dynamical characterisation, by disentangling the contribution of in-situ and ex-situ processes to the history of star formation and effective chemical enrichment of these regions. In addition, the dynamical analysis of these inner regions naturally includes the identification and characterization of galactic winds potentially present in these regions. At a later stage, we will extend this study further out in galactocentric distance. The first stage of this project encompasses the analysis of the central regions of a total of 43 nearby galaxies observed with the MEGARA Integral Field Unit for 114 hours, including both Guaranteed Time and Open Time observations. In this paper we provide a set of all the processed data products available to the community and early results from the analysis of these data regarding stellar continuum, ionized and neutral gas features.Comment: Accepted for publication in Astronomy & Astrophysic

Reliability Study of Inertial Sensors LIS2DH12 Compared to ActiGraph GT9X: Based on Free Code

The study’s purpose was to assess the reliability of the LIS2DH12 in two different positions, using the commercial sensor Actigraph GT9X as a reference instrument. Five participants completed two gait tests on a treadmill. Firstly, both sensors were worn on the wrist and around the thigh. Each test consisted of a 1 min walk for participants to become accustomed to the treadmill, followed by a 2 min trial at ten pre-set speeds. Data from both sensors were collected in real-time. Intraclass correlation coefficient (ICC) was used to evaluate the equality of characteristics obtained by both sensors: maximum peaks, minimum peaks, and the mean of the complete signal (sequence of acceleration values along the time) by each axis and speed were extracted to evaluate the equality of characteristics obtained with LIS2DH12 compared to Actigraph. Intraclass correlation coefficient (ICC) was extracted, and a standard deviation of the mean was obtained from the data. Our results show that LIS2DH12 measurements present more reliability than Actigraph GT9X, ICC > 0.8 at three axes. This study concludes that LIS2DH12 is as reliable and accurate as Actigraph GT9X Link and, therefore, would be a suitable tool for future kinematic studies

Formulación y ajuste de estructuras reguladoras para el manejo de aguas en las sabanas de Arauca y su efecto sobre la producción en el sistema de explotación de bovinos de cría: informe anual

Las actividades de este proyecto se desarrollaron en la vereda Bogotá, a los 6° 51' de latitud norte y 70° 24 de longitud oeste, a una altura de 128 msnm, municipio de Arauca, en la llanura aluvial de desborde, durante el penado comprendido entre enero de 1998 y diciembre de 2001.El estudio agroeconómico realizado en el área de influencia del proyecto, indica que el 70% de los propletanos son onundos del muniCipio de Arauca, predomina la unión libre Las diez familias encuestadas suman un total de 56 personas El 80% de los usuarios tienen educación primaria y 20% secundaria El 100% de los productores encuestados son propietarios y administran personalmente sus fincas.Ganadería bovin

Identification of candidate genes associated with fibromyalgia susceptibility in southern Spanish women: the al‑Ándalus project

Candidate-gene studies on fibromyalgia susceptibility often include a small number of single nucleotide polymorphisms (SNPs), which is a limitation. Moreover, there is a paucity of evidence in Europe. Therefore, we compared genotype frequencies of candidate SNPs in a well-characterised sample of Spanish women with fibromyalgia and healthy non-fibromyalgia women.This work was supported by the Spanish Ministry of Economy and Competitiveness [I+D+i DEP2010-15639, I+D+i DEP2013-40908-R to M.D.-F.; BES-2014-067612 to F.E.-L.]; the Spanish Ministry of Education [FPU2014/02518 to M.B.-C.]; the Consejería de Turismo, Comercio y Deporte, Junta de Andalucía [CTCD-201000019242-TRA to M.D.-F.]; Consejería de Salud, Junta de Andalucía [PI-0520-2016 to M.D.-F.], and the University of Granada, Plan Propio de Investigación 2016, Excellence actions: Units of Excellence; Unit of Excellence on Exercise and Health (UCEES). This work is part of a Ph.D. Thesis conducted in the Biomedicine Doctoral Studies of the University of Granada, Spai