871 research outputs found

    Embracing learner evangelism : bar poker community insights for Minnesota United Methodists

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    https://place.asburyseminary.edu/ecommonsatsdissertations/2248/thumbnail.jp

    The Analgesia-Enhancing Component of\ud Ingested Amniotic Fluid Does Not Affect\ud Nicotine-Induced Antinociception in\ud Naltrexone-Treated Rats

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    Ingestion of amniotic fluid and placenta by rats has been shown to enhance opioid-mediated antinociception but not affect the nonopioid-mediated antinociception produced by aspirin, suggesting spccificity for opioid-mediated processes. However, enhancement by the active substance(s) in amniotic fluid and placenta1 (POEF, for placental opioid-enhancing factor) of antinociception produced by other nonopioid mechanisms has yet to be examined. The present experiments tested whether ingestion of amniotic fluid enhances the antinociception produced by nicotine injection. In Experiment IA, Enhancement of morphine-mediated antinociception by ingestion of amniotic fluid was demonstrated in a hot-plate assay. In Experiment IB, rats pretreated with naltrexone were given an orogastric infusion of amniotic fluid or control (0.25 ml), then injected with nicotine (0, 0.075, 0.125, or 0.225 mg/kg subcutaneously), then tested for antinociception in a hot-plate assay. Amniotic fluid ingestion did not enhance the antinociception produced by various doses of nicotine. In Experiment 2, rats pretreated with naltrexone were given an orogastric infusion of amniotic fluid (0, 0.125,\ud 0.25, or 0.50 ml) and then injectcd with 0.125 mg/kg nicotine. None of the doses of amniotic fluid enhanced the nicotine-induced antinociception. The findings of these experiments lend support to our contention that the enhancement by POEF of antinociception is specific to opioid-mediated processes

    Creative Destruction and Rural Tourism Planning: The Case of Creemore, Ontario

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    This study assesses the relationship between planning and creative destruction in the village of Creemore, Ontario. The study has four objectives. The first is to describe the evolution of tourism in Creemore by tracking change in three variables: investment, visitor numbers and resident attitudes. Second, is to describe past and present tourism planning in the village. Third, is to assess Creemore’s position in the model of creative destruction, based on information presented in objectives one and two. The final objective is to provide recommendations for Creemore’s future based on information gained from the other objectives. To investigate the first objective, entrepreneurial investment was provided by secondary sources, including the Creemore Business Improvement Association (BIA). Visitor numbers were obtained from content analyses of copies of the local newspaper and from information provided by the Creemore Springs Brewery. Resident attitudes were gleaned from a survey completed by 126 residents of Creemore. To meet the second objective, a content analysis was completed on historic issues of the local newspaper and six key informant interviews were conducted. Based on the information provided from the first two objectives, it is concluded that Creemore is in the second stage of Mitchell’s (1998) model of creative destruction, Advanced Commodification. This conclusion is drawn since visitor numbers and investment levels are still low and resident attitudes are generally positive towards tourism. It is also concluded that tourism planning plays a large role in creative destruction, as it can speed up, or slow down, the process, depending on the types of planning that are implemented. Based on the findings of this study, it is recommended that a tourism plan be developed to help mitigate possible future negative impacts of tourism, and to ensure the village does not evolve any further along the path of creative destruction

    Correlation of Pool Drowning Deaths with Number of Residential Swimming Pools by County in Florida, 2005-2007

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    Drowning in residential swimming pools is a significant public health problem in Florida. This study aimed to determine the relationship between the number of pools and pool drowning deaths by county in Florida. County property appraisers’ offices were surveyed to obtain a statewide census of appraised residential pools. The number of pool drowning deaths was obtained from death certificate records. Approximately 1.1 million residential pools were appraised in 2006, and 262 unintentional, confirmed pool drowning deaths occurred from 2005 through 2007. Statistical modeling showed that for every 10,000 residential pools that a county has, 2.4 additional pool drowning deaths can be expected to occur over three years. This relationship was therefore determined to be linearly correlated. Greater public health impact may be achieved by focusing drowning prevention efforts, especially among young children, in counties with more residential pools, and thus a greater risk of pool drowning

    Modelling the future of the Hawaiian honeycreeper : an ecological and epidemiological problem

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    The Hawaiian honeycreeper (Drepanididae) faces the threat of extinction; this is believed to be due primarily to predation from alien animals, endemic avian malaria (Plasmodium relictum) and climate change. A deterministic SI modelling approach is developed, incorporating these three factors and a metapopulation approach in conjunction with a quasi-equilibrium assumption to simplify the vector populations. This enables the qualitative study of the behaviour of the system. Numerical results suggest that although (partial) resistance to avian malaria may be advantageous for individual birds, allowing them to survive infection, this allows them to become carriers of infection and hence greatly increases the spread of this disease. Predation obviously reduces the life-expectancy of honeycreepers, but in turn this reduces the spread of infection from resistant carriers; therefore the population-level impact of predation is reduced. Various control strategies proposed in the literature are also considered and it is shown that predation control could either help or hinter, depending upon resistance of the honeycreeper species. Captive propagation or habitat restoration may be the best feasible solution to the loss of both heterogeneity within the population and the loss of the species as a whole
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