Debuncher Cooling Performance

Abstract. We present measurements of the Fermilab Debuncher momentum and transverse cooling systems. These systems use liquid helium cooled waveguide pickups and slotted waveguide kickers covering the frequency range 4-8 GHz. Keywords: Stochastic Cooling, Antiproton Beams PACS: 41.75.Lx THE FERMILAB DEBUNCHER The Fermilab Debuncher is an 8 GeV ring designed for the collection, RF debunching, and storage of anitprotons. The Tevatron Collider program requires 1e13 antiprotons for the study of proton-antiproton collisions at √ s = 1.96 TeV. Antiprotons are produced by impinging a 120 GeV proton beam on an nickel alloy target and collected through a lithium focussing lens and the Debuncher ring then stochastic stacked in the Fermilab Accumulator PERFORMANCE REQUIREMENTS The Debuncher accepts a few ×10 8 antiprotons every 2 seconds. The input beam fills the transverse aperture of the beam, consistent with a transverse emittance of 320π mm mr (95% unnormalized). At the end of the 2 second cycle, the beam is required to have transverse emittance less than 45π mm mr (95% unnormalized) in both planes (factor of 7). After bunch rotation, the 95% momentum width is approximately 60 MeV/c. At the end of the 2 second cycle, the 95% momentum width of the beam is required to be less than 6 MeV/c (factor of 10). These requirements correspond to a 6-dimensional phase space density (ρ 6d = N particles ε l ε h ε v ) increase of a factor of 500

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.

GWAS have identified >200 risk loci for Inflammatory Bowel Disease (IBD). The majority of disease associations are known to be driven by regulatory variants. To identify the putative causative genes that are perturbed by these variants, we generate a large transcriptome data set (nine disease-relevant cell types) and identify 23,650 cis-eQTL. We show that these are determined by ∼9720 regulatory modules, of which ∼3000 operate in multiple tissues and ∼970 on multiple genes. We identify regulatory modules that drive the disease association for 63 of the 200 risk loci, and show that these are enriched in multigenic modules. Based on these analyses, we resequence 45 of the corresponding 100 candidate genes in 6600 Crohn disease (CD) cases and 5500 controls, and show with burden tests that they include likely causative genes. Our analyses indicate that ≥10-fold larger sample sizes will be required to demonstrate the causality of individual genes using this approach

Moisture content characterization in composite materials based on ultrasonic transmission measurements

International audienc

Veue de la ville et du siége d'Oudenarde, où le Roy commande en personne en l'année 1667 : [estampe]

Référence bibliographique : Hennin, 444

Saint-Omer veu du costé du fort de Bournonville assiégé et pris par l'armée du Roy, sous le commandement de Monsieur duc d'Orléans, en avril 1677 : [estampe]

Référence bibliographique : Hennin, 492