12 research outputs found
Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 24/10/2017
- Field of study
Understanding the transcription factors that modulate epithelial resistance to injury is necessary for understanding intestinal homeostasis and injury repair processes. Recently, transcription factor EB (TFEB) was implicated in expression of autophagy and host defense genes in nematodes and mammalian cells. However, the in vivo roles of TFEB in the mammalian intestinal epithelium were not known. Here, we used mice with a conditional deletion of Tfeb in the intestinal epithelium (Tfeb ΔIEC) to examine its importance in defense against injury. Unperturbed Tfeb ΔIEC mice exhibited grossly normal intestinal epithelia, except for a defect in Paneth cell granules. Tfeb ΔIEC mice exhibited lower levels of lipoprotein ApoA1 expression, which is downregulated in Crohn’s disease patients and causally linked to colitis susceptibility. Upon environmental epithelial injury using dextran sodium sulfate (DSS), Tfeb ΔIEC mice exhibited exaggerated colitis. Thus, our study reveals that TFEB is critical for resistance to intestinal epithelial cell injury, potentially mediated by APOA1
Oral Health Disparities in Children
- Author
- American Academy of Pediatrics
- Anders
- Bambra
- Bastos
- Batis
- Bernstein
- Boillot
- Cecchini
- Chetty
- Conway
- Costa
- Da Rosa
- Da Silveira Moreira
- Delgado-Angulo
- Do
- Dye
- Edelstein
- Edelstein
- Edelstein
- Edelstein
- Enjary
- Fine
- Fisher-Owens
- Fisher-Owens
- Flores
- Gatou
- Graham
- Guerrero-López
- Hartnett
- Ibarra
- Iheozor-Ejiofor
- Institute of Medicine and National Research Council
- Jaafar
- Jackson
- Jun Aida
- Junqueira
- Keller Celeste
- LaVeist
- Lazarus
- Le
- Lee
- Levin
- Lin
- Locker
- Lupo
- Macintyre
- Mackenbach
- Manu Raj Mathur
- Marcelo Bönecker
- Marcenes
- Marmot
- Marmot
- Masood
- Mathews
- Mathur
- McDonagh
- McKinlay
- McMahon
- Mendoza
- Murthy
- Nash
- National Academics of Sciences
- National Health and Medical Research Council
- Newacheck
- Newton
- Nicolau
- Park
- Perera
- Perera
- Petersen
- Petersen
- Piketty
- Public Health England
- Public Health England
- Reisine
- Renato Venturelli
- Richard G. Watt
- Rizk
- Roberts
- Rozier
- Sabbah
- Sanders
- Schou
- Schwendicke
- Sen
- Sheiham
- Silk
- Sisson
- Slade
- Spencer
- Stuart A. Gansky
- Thomson
- Tomar
- US Department of Health and Human Services Oral Health Coordinating Committee
- Valencia
- Watt
- Watt
- Watt
- Wilkinson
- World Health Organization Commission on Social Determinants of Health
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Compilación de Proyectos de Investigacion de 1984-2002
- Author
- Abad Ruiz Emilia
- Aguilar y Oros Armando D.
- Ahumada Vargas Joel
- Alarid Prieto Jaime
- Alvarado Affantrager Elías
- Amador Barrón Manuel Pérez
- Arce Arnez Jorge
- Arriaga García José Ernesto
- Baca Urbina Gabriel
- Benítez Cervantes Raúl
- Bojórquez Hernández Francisco
- Bueno Díaz Marcela
- Bustamante Domínguez Arturo
- Cahue López Ignacio
- Cano García Rogelio
- Castillo Santistebe Rubén
- Caudillo Vargas José Luis
- Ceja Mena Luis Ignacio
- Contreras Hernández Leticia
- Contreras Hernández Mario
- Cruz Valderrama Margarita
- Del Carmen Castillo María
- Del Castillo Jaime Raúl
- Escobar Salcedo Refugio
- Esquivel Granados Alberto
- Evaristo Trujano Gaspar
- Fabián Ruiz José Luis
- Feregrino Aguilar Ricardo
- Fernández Vela Ma. Del Socorro
- Ferrán Villanueva Carmen
- Figueroa Giles Guillermo
- Flores García Aurelio
- Fonseca Monterrubio María de los Ángeles
- Franco Espejel Gilda Melva
- Fuenlabrada Velázquez Sergio
- Galindo Soria Fernando
- Gallegos de la Cruz Apolino
- Gallegos de la Cruz Apolonio
- Gamiño López Martha
- García Córdoba Francisco Fernando
- García Galindo Dolores
- García Martínez José G.
- García Montiel Josefina
- García Morales Miguel
- García Nieto María del Pilar
- García Ruiz Amado
- Garza Ramos Francisco Jiménez
- Garzón Arias José
- González Barragán Teresa
- González Ruiz Lucinda
- González Zúñiga Domingo
- Gordillo Mejía Abraham
- Guerrero Briseño Manuel
- Gutiérrez González Eduardo
- Guzmán Ibarra Virginia
- Gómez Chávez Salome
- Gómez García Joas
- Hernández Hernández Jorge
- Hernández Pérez Petra
- Hurtado Moreno Juan José
- Islas Rivera Víctor
- Jiménez Castellanos Roberto
- Jiménez Jerez Sergio Raúl
- Julio García Sylvio
- Jáuregui Honorato Susana
- Laguna Mancilla Ramón
- Larios García Raúl
- Leticia Hernández Martha
- León García Daniel
- López Berzuna Enrique
- López Berzunza Enrique
- López Brant Jorge
- López Gracia Julián
- López Herrera Alfredo
- López Medina Manuel
- Madrigal Romero Manuel
- Martínez Alcázar José Luis
- Martínez Armenta Rosa María
- Martínez Figueroa Mario Luis
- Martínez Márquez Alejandro
- Medina Malagón Gabriel
- Medina Márquez Alejandro
- Mejía Elías Marcelo
- Mendoza Melken Luis Fernando
- Mendoza Núñez Zoilo
- Mendoza Valencia Juvenal
- Mises González Roberto
- Montes de Oca Ricardo
- Montiel Ramírez Pompeyo
- Morales Hernández José L.
- Morales Hernández José Luis
- Morales Marín Armando
- Munch Galindo Lourdes
- Méndez García José Claudio
- Méndez Girón Alejandra
- Nateras Soto Ernestina
- Navarrete Balderas Rafael
- Oliva López Eduardo
- Olivera García Hilda
- Ontiveros Álvarez Mario Daniel
- Ortiz Lira Gerardo
- Ortiz Pérez Víctor Hugo
- Ortiz Pérez Víctor Hugo
- Oviedo Galdeano Humberto
- Oviedo Galdeano Mario
- Pacheco Espejel Arturo
- Pacheco Espejel Arturo
- Pereyra Ortiz Enrique
- Pineda Domínguez Daniel
- Pinto Salazar Martin
- Ponce Maldonado Gustavo
- Prieto Varela Fernando
- Procel Moreno Mauricio J.
- Pérez Tenorio Roberto
- Pérez Vázquez Fernando Roberto
- Pérez Vázquez Guillermo
- Rabadan Calvillo Raúl
- Ramírez Tapia Moisés
- Ramírez Torres Francisco
- Ramón y de la Parra Francisco
- Reyes Córdova Felipe
- Reyes García Juan Ignacio
- Reyes Ibarra Ignacio
- Rivera Carreño Raúl
- Rodríguez Jiménez Ramón
- Rodríguez Mercado Sara
- Rodríguez Perego Nicolás
- Rojas Cruz José Cruz
- Romero Vallejo José Sergio
- Rosales de la Vega Sergio
- Saavedra Pérez Javier
- Saavedra Pérez Javier
- Salazar Peralta Yolanda
- Salcedo Baca Reynalda
- Salinas Cárdenas Leticia
- San Juan Victoria Aida Osvelia
- Sandoval Alfaro Vicente
- Santiago Toledo Jesús
- Sesma Martínez Mario Alberto
- Silva Mendoza Edith
- Silva Mendoza Edith Rosa
- Sonck Ledezma Judith
- Sorkin Álvarez Moisés
- Sosa Altamirano Rodolfo
- Suarez Martínez Alberto
- Sánchez Favila José
- Tapia Aguilar Ángel E.
- Toledo Trejo Javier
- Torres Duran Miguel A.
- Torres Merino Jesús
- Torres Márquez Clara
- Trejo Parada Guadalupe E.
- Valencia Velasco Lourdes
- Velasco Flores José Luis
- Vicario Solórzano Claudia Marina
- Vázquez Torres Fernando
- Yáñez Rivera Jacinto
- Zafra Orduña Alberto
- Zurita Ochoa Félix
- Álvarez Castorela Víctor
- Álvarez González Enrique
- Ángeles Mejía Ernesto A.
- Publication venue
- Instituto Politécnico Nacional (IPN)
- Publication date
- 25/06/2012
- Field of study
Instituto Politecnico Nacional. UPIICS
Effect of the COVID-19 pandemic on surgery for indeterminate thyroid nodules (THYCOVID): a retrospective, international, multicentre, cross-sectional study
- Author
- Abdallah A
- Abentroth AL
- Acheimastos V
- Agunaoun M
- Al Bisher HM
- Al Ghuzlan A
- Al-Suhaimi Ebtesam Abdullah
- Alakus H
- Alkan M
- Almaraz Almaraz MC
- Altmeier Julia
- Amram K
- Anajar Said
- Anesidis S
- Anestiadou E
- Angelucci D
- Ansaldo GL
- Antonopoulou MI
- Arciniegas M
- Arikan Akif Enes
- Armellin C
- Arredondo Saldaña G
- Astl J
- Athanasakis E
- Avenia S
- Aydın H
- Azaryan Irina
- Baba B
- Babala J
- Bains Lovenish
- Banús MV
- Barba-Valadez LA
- Barcons SV
- Basili Giancarlo
- Battafarano F
- Bayat A
- Bella RMC
- Benariba F
- Bernardi S
- Bignami EG
- Bitenc M
- Bitsianis S
- Bolaños de la Torre JDD
- Bolukbasi Hakan
- Bonati E
- Bonetti T
- Bononi Marco
- Borges FA
- Borumandi Farzad
- Bouchagier K
- Boudina M
- Bourial A
- Bozan Mehmet Buğra
- Brenta Gabriela
- Breuskin I
- Brock P
- Brunaud Laurent
- Brunner Maximilian
- Bruns C
- Buemi Antoine
- Burlacu MC
- Burton T
- Buta M
- Buzanakov D
- Caliseo C
- Callanan D
- Calu V
- Calò Pietro Giorgio
- Cameselle-Teijeiro JM
- Camilo-Junior DJ
- Canberk S
- Candalise V
- Candanedo-Gonzalez F
- Canu Gian Luigi
- Cappellacci Federico
- Carrillo Lizarazo LJ
- Cartwright Sara Burchfield
- Carvalho GB
- Casallas D
- Casolino C
- Castellani L
- Castells Fusté Ignasi
- Castillo Morales C
- Cavalheiro Beatriz
- Cavallaro Giuseppe
- Chala Andres
- Chambon G
- Chan Shun Yan Bryant
- Chaplin John
- Chatzipavlidou V
- Cheema Mustafa Sajjad
- Chernikov R
- Chiapponi Costanza
- Chiofalo Maria Grazia
- Chorti A
- Chow TCM
- Chrisoulidou A
- Chrysos E
- Chrysos Emmanuel
- Conrado-Neto S
- Cordova García D
- Corigliano A
- Crocco A
- Cuesta A
- Curto LS
- D'Amore Annamaria
- D'Anna R
- D'Orazi Valerio
- Damilano RA
- de Cillia Michael
- De Crea Carmela
- de Manzini Nicolò
- de Matos Leandro Luongo
- De Pasquale Loredana
- De Virgilio A
- De M
- Del Rio Paolo
- Dellaportas D
- Demarchi Marco Stefano
- Demarquet L
- Devresse A
- Dhiwakar Muthuswamy
- Di Meo G
- Diaz Pedrero R
- Dimitrov D
- Dmitry Z
- Dobrinja Chiara
- Domínguez Garijo P
- Donatini Gianluca
- Dora Jose Miguel
- Doulatram Gamgaram Viyey Kishore
- Dulgeroglu O
- Dural AC
- Eismontas Vitalijus
- Eksi A
- El Hammoumi M
- El Kaoui H
- El Malki Hadj Omar
- Eleni G
- Elliyanti A
- Elzahaby Islam
- Enciu Octavian
- Ersöz Ş
- Escobar-Jiménez M
- Eskander Antoine
- Fedorova L
- Feeley L
- Fernández Rodríguez E
- Feroci Francesco
- Ferreli F
- Figueroa-Bohorquez David
- Filis Dimitrios
- Filoia A
- Fingeret A
- Francescato A
- François Gorostidi
- Frías-Fernández Pedro
- Gaino F
- Galiandro F
- Gallegos-Hernández JF
- Gamboa-Dominguez Armando
- Garas G
- García Lorenzo F
- García-Chávez JP
- Gaudiello M
- Gay S
- Genc Volkan
- Gerasimos S
- Gerek M
- Gervasi R
- Giordano A
- Giordano Davide
- Gjeloshi B
- Gocký L
- Golubinskaya E
- González Romero S
- González-Mínguez C
- Goran M
- Gosman A
- Graceffa Giuseppa
- Granados Garcia M
- Greco E
- Griffin James
- Grünbart M
- Grützmann R
- Guerlain J
- Guerreiro Sofia Cuco
- Guirao XG
- Gupta Karan
- Gupta Keshav Kumar
- Gurrado Angela
- Guzey D
- Gómez-Pedraza Antonio
- Hajiioannou Jiannis
- Hajjij A
- Hakala Tommi
- Hamdy O
- Hameed MS
- Harahap Wirsma Arif
- Hargitai Lindsay
- Hartl Dana
- Hauth LA
- Hellmann Andrzej
- Hernandez-Carrillo JF
- Hernández-Acevedo JD
- Hevilla Sánchez F
- Hlozek Jiri
- Hoang Van Trung
- Hoi H
- Hongkwon K
- Hu Zhu R
- Huang E
- Hyeung Kyoo K
- Iacobone Maurizio
- Ignjatovic V
- Innaro Nadia
- Ioannidis A
- Ioannidis Orestis
- Iossa A
- Işık A
- James D
- Jang J H Isabelle
- Jovanovic Milan
- Jung Hoon L
- Kabiri El Hassane
- Kaderli Reto Martin
- Kakamad Fahmi
- Kaliszewski Krzysztof
- Kara H
- Karajovic J
- Karamanliev Martin
- Kartini D
- Katoh Hiroshi
- Khambri D
- Kholová I
- Kim Soo Young
- Kisiel M
- Knežević M
- Koh YQ
- Konca C
- Kosmidis C
- Kotsovolis G
- Kovacevic Bozidar
- Kowalski LP
- Kowalski Luiz Paulo
- Košec Andro
- Kralik R
- Králik Robert
- Kuczma P
- Kumorová Adriána
- Kuravi BG
- Kurnia A
- Kyriaki V
- Lai CM
- Lallemant B
- Lampridis Savvas
- Lardhi AA
- Lasithiotakis Konstantinos
- Leboulleux S
- Leclere Jean-Christophe
- Lee JW
- Lelli G
- Leong Eugene Kwong Fei
- Leow Melvin Khee-Shing
- Leutner M
- Lim CM
- Lim James Y
- Lim MY
- Lino-Silva Leonardo S
- Liu Shirley Yuk Wah
- Llanos A
- Llorach Núria Perucho
- Lo X
- Loderer T
- Lombardi Celestino Pio
- Lori Eleonora
- Lucchini Roberta
- Ludwig M
- López-Corrales MA
- López-Gómez Javier
- Madani Amin
- Magnabosco FF
- Maheo C
- Maia AL
- Makay O
- Maksimova P
- Mallick S
- Mallouk C
- Mamani Z
- Manatakis Dimitrios
- Mandal S
- Manyalich Blasi M
- Marincola G
- Markovic Ivan
- Marulanda M
- Materazzi Gabriele
- Mavromati M
- Mayilvaganan S
- Mazeh Haggi
- Medas Fabio
- Mercante Giuseppe
- Metso S
- Meyer-Rochow Goswin Yason
- Micalizzi A
- Michalopoulos A
- Mihaljevic Olgica
- Miller Julie A
- Min-Su K
- Minuto Michele
- Miron A
- Mishra AK
- Misso C
- Mittermair C
- Monacelli Massimo
- Morosán Allo Y
- Mourad M
- Moysidis M
- Mulita Francesk
- Mullineris Barbara
- Muradás Girardi Fábio
- Muñoz-de-Nova José Luis
- Nabhan F
- Nader Saki
- Napadon Tangjaturonrasme
- Nasiri R
- Nastos C
- Nastos Constantinos
- Ngiam KY
- Nomine-Criqui C
- Ntziovara AM
- Nutautiene V
- Nuño Vázquez-Garza JM
- O'Keeffe L
- Obtulovičová K
- Offi Chiara
- Okudur NO
- Oragano Luigi
- Orois Aida
- Ossola P
- Ovejero Merino E
- Ozdemir M
- Pan Yongqin
- Panagiotidis Emmanouil
- Panchangam Ramakanth Bhargav
- Pangonis A
- Panigoro SS
- Panuzi A
- Papaconstantinou D
- Papavramidis Theodosios
- Pardo Matamoros N
- Parida Pradipta Kumar
- Paschou S
- Pasculli A
- Paspala Anna
- Paterakis K
- Peiris K
- Pennestrì F
- Peppa M
- Perdikaris I
- Perdikaris P
- Petrovic Sabrina
- Piana S
- Piccoli M
- Pietrasanta D
- Placentino G
- Pliakos I
- Polistena A
- Pongtippan A
- Potard G
- Pérez Òscar Vidal
- Pérez-Soto RH
- Quinn V
- Quintanilla-Dieck Lourdes
- Raffaelli Marco
- Rahul P
- Ramacciotti Constanza Fernanda
- Ramos T
- Rankin A
- Ratia Gimenez Tomas
- Ratnayake P
- Reuto-Castillo J
- Ridolfo A
- Rios-Valencia J
- Riss P
- Rival E
- Rivillas J
- Rivo Vázquez Ángel
- Roh Jong-Lyel
- Roi D
- Rollo EM
- Romanchishen A
- Romito M
- Ronen Ohad
- Rossi Leonardo
- Rotnagl J
- Rovcanin B
- Russo G
- Sabol M
- Saki S
- Saleh S
- Salih A
- Saltiki A
- Salvador-Camarmo G
- Samal DK
- Sanabria Alvaro
- Santeerapharp Alena
- Sapalidis K
- Sarin D
- Sarin H
- Savkovic N
- Scheffel RS
- Scheinpflug AL
- Scheuba C
- Scheyer N
- Schmidt M
- Semenov Arseny
- Senashova O
- Seneviratne Sanjeewa
- Serafini E
- Serdar Altinay
- Serrano Arévalo ML
- Shank J
- Sheahan Patrick
- Sheppard Sean C
- Shindo ML
- Shoshkova M
- Shvan M
- Silva TG
- Simó Guerrero O
- Sičák M
- Skuletic V
- Slijepcevic N
- Slotcavage Rachel L
- Slovic Z
- Smaxwil Constantin
- Soares P
- Somova A
- Sorrenti Salvatore
- Soto S
- Spartalis Eleftherios
- Spiezia S
- Sriphrapradang Chutintorn
- Stankovic V
- Stephenson KJ
- Straub E
- Summa M
- Surani S
- Syed AA
- Symeonidis S
- Sánchez-Flores S
- Taciak A
- Tarallo M
- Tarle A
- Tasis N
- Tausanovic K
- Tchabashvili L
- Testini Mario
- Thierry M
- Tokarczyk U
- Toma EA
- Topuz S
- Torresan F
- Turk Yigit
- Tzikos George
- Uras C
- Vabalayte Kristina
- Vaccaro C
- Valdés de Anca Á
- Valentini M
- Varaldo E
- Vargas-Osorio Kelly
- Vartanian JG
- Velázquez-Fernández David
- Verras GI
- Vithana Sanura Malinda Pallegoda
- Vithanage A
- Vázquez Rentería Rafael Sebastián
- Wijayalathge H
- Wiriyaamornchai P
- Wong YLC
- Wongwattana P
- Xavier-Junior Jose Candido
- Xenaki S
- Xie S
- Xu M
- Yadav Sanjay Kumar
- Yang W
- Yilmaz S
- Yılmaz YF
- Yotsov T
- Yulian Erwin Danil
- Yücel Levent
- Zahid MT
- Zahradnikova Petra
- Zarogoulidis Paul
- Ziablitskaia Evgeniia
- Zielke A
- Zolotoukho Anna
- Čukman M
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background: Since its outbreak in early 2020, the COVID-19 pandemic has diverted resources from non-urgent and elective procedures, leading to diagnosis and treatment delays, with an increased number of neoplasms at advanced stages worldwide. The aims of this study were to quantify the reduction in surgical activity for indeterminate thyroid nodules during the COVID-19 pandemic; and to evaluate whether delays in surgery led to an increased occurrence of aggressive tumours.
Methods: In this retrospective, international, cross-sectional study, centres were invited to participate in June 22, 2022; each centre joining the study was asked to provide data from medical records on all surgical thyroidectomies consecutively performed from Jan 1, 2019, to Dec 31, 2021. Patients with indeterminate thyroid nodules were divided into three groups according to when they underwent surgery: from Jan 1, 2019, to Feb 29, 2020 (global prepandemic phase), from March 1, 2020, to May 31, 2021 (pandemic escalation phase), and from June 1 to Dec 31, 2021 (pandemic decrease phase). The main outcomes were, for each phase, the number of surgeries for indeterminate thyroid nodules, and in patients with a postoperative diagnosis of thyroid cancers, the occurrence of tumours larger than 10 mm, extrathyroidal extension, lymph node metastases, vascular invasion, distant metastases, and tumours at high risk of structural disease recurrence. Univariate analysis was used to compare the probability of aggressive thyroid features between the first and third study phases. The study was registered on ClinicalTrials.gov, NCT05178186.
Findings: Data from 157 centres (n=49 countries) on 87 467 patients who underwent surgery for benign and malignant thyroid disease were collected, of whom 22 974 patients (18 052 [78·6%] female patients and 4922 [21·4%] male patients) received surgery for indeterminate thyroid nodules. We observed a significant reduction in surgery for indeterminate thyroid nodules during the pandemic escalation phase (median monthly surgeries per centre, 1·4 [IQR 0·6-3·4]) compared with the prepandemic phase (2·0 [0·9-3·7]; p<0·0001) and pandemic decrease phase (2·3 [1·0-5·0]; p<0·0001). Compared with the prepandemic phase, in the pandemic decrease phase we observed an increased occurrence of thyroid tumours larger than 10 mm (2554 [69·0%] of 3704 vs 1515 [71·5%] of 2119; OR 1·1 [95% CI 1·0-1·3]; p=0·042), lymph node metastases (343 [9·3%] vs 264 [12·5%]; OR 1·4 [1·2-1·7]; p=0·0001), and tumours at high risk of structural disease recurrence (203 [5·7%] of 3584 vs 155 [7·7%] of 2006; OR 1·4 [1·1-1·7]; p=0·0039).
Interpretation: Our study suggests that the reduction in surgical activity for indeterminate thyroid nodules during the COVID-19 pandemic period could have led to an increased occurrence of aggressive thyroid tumours. However, other compelling hypotheses, including increased selection of patients with aggressive malignancies during this period, should be considered. We suggest that surgery for indeterminate thyroid nodules should no longer be postponed even in future instances of pandemic escalation.
Funding: None
International Nosocomial Infection Control Consortiu (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module
- Author
- Abdullah Mufareh Assiri
- Abeer Ahmed Mohmed
- Abeer Aly Omar
- Abhijeet Raha
- Abizer Nuruddin Manked
- Achilleas Gikas
- Adela Arguello Ruiz
- Adem Karbuz
- Adrian M. Puello Guerrero Glenny Mirabal
- Adriana Montanini
- Adriana Romani
- Afzal Azim
- Agamenon Alves Oliveira
- Agreta Gecaj-Gashi
- Ahmed Hakawi
- Ahmet Dilek
- Aisha Mubarak
- Ajoy Krishna Sarkar
- Alexander Molkov
- Alexander Tchekulaev
- Alfredo Lagares Guzman
- Alfredo Paucar
- Algirdas Dagys
- Ali Kaya
- Ali Metin Otkun
- Ali Omer Abdul Aziz
- Ali Pekcan Demiroz
- Aline Besen
- Aliye Yasayacak
- Alka Thool
- Alka Thool
- Alper Sener
- Altaf Ahmed
- Alysia Faye Giani
- Alzbeta Marcekova
- Amani Ali El-Kholy
- Amani Fouad Sayed
- Amaury Mielle Filho
- Ameurfina Curioso Silo
- Amine Ali Zeggwagh
- Amjad Mahboob
- Amna Mostafa Mohamed
- Amol Harshe
- Ana Lucía Bonilla Escudero
- Ana Marãa Perez Fernandez
- Ana Paula Fontes Pinheiro
- Ana Paula Vasconcelos Carneiro
- Ana Silvia Rearte
- Anahita Sanaei
- Analen Fabros Cabato
- Andrea Peña Padilla
- Andres Eduardo Mindiola Rochel
- Andres H. Corchuelo Martinez
- Andrzej Kubler
- Angel Gonzalez Vargas
- Angel Orlando Flores Alvarado
- Angelina Mendonca
- Anil Bilolikar
- Anil Karlekar
- Anirban Karmakar
- Anis Shiham Zainal Abidin
- Anju Mathew
- Anna Lesnakova
- Annalyn Amor Malificio
- Antigona Hasani
- Antonio Claudio do Amaral Baruzzi
- Antonio Martinez Mulia
- Antonio Solano Chinchilla
- Anu Kurian
- Anucha Apisarnthanarak
- Anuja Kedar Kulkarni
- Anuradha Agarwal
- Anwar Al Souheil
- Anzar Thair
- Aparajita Panda
- Aparecida Camacho
- Apsia Musa Molano
- Araceli Martinez Martinez
- Areej Dhafer Alshehri
- Arifa Hafeez
- Arjun Rajalakshmi
- Arlu Marie Casuyon Pahilanga
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- Rosalia Fernández-Hidalgo
- Rosana Richtmann
- Rosita Gasmin Aromin
- Ruby Jose Ramapurath
- Rungratchanee Pimathai
- Rédouane Abouqal
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- S.N. Myatra
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- Saban Esen
- Saeed Ali Al Darani
- Salih Cesur
- Sameeh Salem Ghazal
- Samir Sahu
- Samir Sahu
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- Sanghamitra Mishra
- Sanjay Bhattacharya
- Sanjay Singhal
- Sanjeev Singh
- Sanjeev Sood
- Sankar Sengupta
- Santosh Singh
- Sarika Juneja
- Saroj Kumar Patnaik
- Sasheela Sri La Sri Ponnampala
- Saswati Sinha
- Seelas Blessymole
- Sehnaz Kaya
- Selene Manga Chavez
- Selin Bardak
- Selvi Yener Erdogan
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- Sergey Puzanov
- Sergio Blecher
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- Serhat Unal
- Sevim Karacorlu
- Shamsher Dalal
- Sheena Binu
- Sheena Mary Sibin
- Shefali Bhattacharya
- Shirley Tenorio López
- Shobhana Kumari Kadankunnel
- Shoeb Nizamuddin Kardekar
- Shufang Wang
- Shufang Zhuo
- Sibel Bolukcu
- Silom Jamulitrat
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- Simone Amorim
- Siva Kumar
- Sladjana Vasiljevic
- Sneha Mary George
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- Socorro Torres Zegarra
- Sohini Arora
- Solange Regina Oliveira Castro
- Somayeh Jahani-Sherafat
- Sona Hlinkova
- Sonali Khamkar
- Sonay Incesoy Ozdemir
- Song Liqiang
- Sonia Joseph
- Soniya Thorat
- Souha Sami Kanj
- Soumya Samal
- Srdjan Pasic
- Srinivas Samavedam
- Subhash Kumar Todi
- Subodh Kumar
- Sudhir Gupta
- Sudhiranjan Misra
- Suga Thomas Varghese
- Suha Sen
- Suhas Nirkhiwale
- Sujata Malik
- Sujith Sujith
- Sujoy Mukherjee
- Sukanya Rangaswamy
- Suman Singh
- Sumana Baidya
- Sumi Nandwani
- Summiya Nizamuddin
- Sumru Ozkan
- Suneeta Sahu
- Sunil Bhamare
- Sunil Sharma
- Suo Yao
- Supriya Chabukswar
- Suresh Kumar
- Susana Gutierrez-Martinez
- Susmita Basu
- Suthinee Wanitanukool
- Suvin Shetty
- Suwara Somabutr
- Suzan Sacar
- Suzette A. Bunsay
- Swarna Banergee
- Swathy Sathish
- Sweta Shah
- Syed Faisal Mahmood
- Syed Zahid Bukhari
- Tahsine Mahfouz
- Tala Kardas
- Tamiris Moreira
- Tanıl Kendirli
- Tanja Anguseva
- Tanu Singhal
- Tao Lili
- Tarek Dendane
- Tarquino Eristidesg Sanchez
- Tatiane T. Rodrigues
- Tenzin Zompa
- Teodora Atencio-Espinoza
- Tereza De Jesus Pinheiro Gomes Bandeira
- Thara Francis
- Thejas Vini
- Tomas Kondratas
- Tomasz Lazowski
- Tran Thi My Hanh
- Tran Thi Thuy Hang
- Trudell Mapp
- Truong Anh Thu
- Tânia Mara Lima De Barros Araújo
- Ufuk Cakir
- Umesh Gupta
- V. Raut
- V.R. Ramanan
- Vaibhavi R. Subhedar
- Vaidotas Gurskis
- Valentina Tulupova
- Valter Furlan
- Vanessa A. Marquez Mondalgo
- Vanessa Bermudez
- Vatsal Kothari
- Velmira Angelova Velinova
- Velu Pandi Suresh Kumar
- Vempati Venkateshwar
- Victor Dumitrascu
- Victoria D. Villanueva
- Vikram Padbidri
- Vineya Rai
- Violeta Jivkova Dicheva
- Visanu Thamlikitkul
- Vladimir Kretov
- Vladimir Shalapuda
- Vladislav Belskiy
- Vo Thi Hong Thoa
- Víctor Daniel Rosenthal
- Walter Enrique Prudencio Leon
- Walter Enrique Prudencio Leon
- Wan Nurbayah Wan Yusoff
- Wania Vasconcelos de Freitas
- Wieslawa Duszynska
- Wilmer Villamil-Gomez
- Wong Kang Kwong
- Wu Kangxiong
- Xihua Geng
- Xiuqin Guo
- Xu Ziqin
- Xuesong Yang
- Yasemin Gelebek
- Yassir Khidir Mohammed
- Yatin Mehta
- Yazmin Leon Vega
- Yiang Shumei
- Yuet-Meng Cheong
- Yuri Mariela Perez Hernandez
- Yvis Ruiz
- Zan Mitrev
- Zaneta Bogoevska-Miteva
- Zeina Kanafani
- Zeinab Salah Seliem
- Zenaida Durán Gil De Añez
- Zeynel Gokmen
- Zeynep Kaya
- Ziad Ahmed Memish
- Zoila Rosa Diaz Tavera
- Zoila Rosa Diaz Tavera
- Çağlar Ödek
- Publication venue
- Elsevier Inc
- Publication date
- 01/09/2014
- Field of study
We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care–associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC's ICUs for an aggregate of 3,338,396 days. Although device utilization in the INICC's ICUs was similar to that reported from ICUs in the U.S. in the CDC's NHSN, rates of device-associated nosocomial infection were higher in the ICUs of the INICC hospitals: the pooled rate of central line–associated bloodstream infection in the INICC's ICUs, 4.9 per 1,000 central line days, is nearly 5-fold higher than the 0.9 per 1,000 central line days reported from comparable U.S. ICUs. The overall rate of ventilator-associated pneumonia was also higher (16.8 vs 1.1 per 1,000 ventilator days) as was the rate of catheter-associated urinary tract infection (5.5 vs 1.3 per 1,000 catheter days). Frequencies of resistance of Pseudomonas isolates to amikacin (42.8% vs 10%) and imipenem (42.4% vs 26.1%) and Klebsiella pneumoniae isolates to ceftazidime (71.2% vs 28.8%) and imipenem (19.6% vs 12.8%) were also higher in the INICC's ICUs compared with the ICUs of the CDC's NHSN
The very forward CASTOR calorimeter of the CMS experiment
- Author
- Aarrestad TK
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdalla H
- Abdullah WATW
- Abdullin S
- Abercrombie D
- Acharya H
- Acosta D
- Acosta JG
- Adam W
- Adamov G
- Adams E
- Adams MR
- Adams T
- Adan DP
- Adloff C
- Adzic P
- Afanasiev S
- Agapitos A
- Agarwal G
- Aggleton R
- Agram JL
- Aguilar-Benitez M
- Agyel D
- Ahmad A
- Ahmad M
- Ahmad WH
- Ahmed A
- Ahuja S
- Aida Junior WL
- Akbiyik M
- Akchurin N
- Akgun B
- Akpinar A
- Al-Bataineh A
- Albajar C
- Albergo S
- Albert A
- Albrow M
- Alcaraz Maestre J
- Aleksandrov A
- Alexander J
- Alhusseini M
- Alimena J
- Alison J
- Allen B
- Almond J
- Alvarez Fernandez A
- Alvarez Gonzalez B
- Alverson G
- Alves GA
- Aly R
- Alyari M
- Amapane N
- Ambrogi F
- Amendola C
- Amin N
- Amram O
- Amsler C
- Anagnostou G
- Anagul S
- Anampa KH
- Anderson D
- Andrea J
- Andreev V
- Andreev Y
- Andrews MB
- Androsov K
- Ang L
- Angioni GLP
- Antchev G
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Apresyan A
- Apyan A
- Araujo M
- Arcaro D
- Arcidiacono R
- Arenton MW
- Argiro S
- Arneodo M
- Aruta C
- Asavapibhop B
- Asawatangtrakuldee C
- Asenov P
- Asghar MI
- Asilar E
- Askew A
- Aslanoglou X
- Asmuss P
- Atakisi IO
- Atanasov I
- Ather MW
- Attikis A
- Auffray E
- Aushev T
- Auzinger G
- Avati V
- Avery P
- Avila C
- Awan MIM
- Ayala E
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzurri P
- Baarmand MM
- Babaev A
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- Voutilainen M
- Voytishin N
- Wadud MA
- Wagner SR
- Walczak M
- Wallny R
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- Wassmer M
- Watson IJ
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- Weber M
- Weinberg M
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- Wezenbeek L
- Whitbeck A
- Wichmann K
- Wickramage N
- Wickramarathna DDC
- Wiedenbeck S
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- Wilson G
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- Winer BL
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- Wisecarver A
- Wissing C
- Wittich P
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- Wong WY
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- Woodard A
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- Wozniewski S
- Wright D
- Wu Z
- Wuchterl S
- Wulz CE
- Wurthwein F
- Wuyckens S
- Wyslouch B
- Xia F
- Xiao J
- Xiao M
- Xiao R
- Xie S
- Xie W
- Yagil A
- Yalvac M
- Yang D
- Yang UK
- Yang YC
- Yao Y
- Yates BR
- Yazgan E
- Yetkin EA
- Yi K
- Yohay R
- Yoo HD
- Yoo J
- Yoon I
- You Z
- Yu D
- Yu GB
- Yu I
- Yu SS
- Yuan L
- Yuan S
- Yumiceva F
- Yusli MN
- Zabi A
- Zacharopoulou A
- Zahid S
- Zaleski S
- Zalewski P
- Zanetti M
- Zarubin A
- Zarucki M
- Zecchinelli AG
- Zenaiev O
- Zenz SC
- Zeuner WD
- Zghiche A
- Zhang A
- Zhang F
- Zhang H
- Zhang J
- Zhang S
- Zhang W
- Zhang Y
- Zhang Z
- Zhao J
- Zhizhin I
- Zhokin A
- Zhu DH
- Zhu RY
- Ziemons T
- Zientek M
- Zlebcik R
- Zobec J
- Zoi I
- Zolkapli Z
- Zorbakir IS
- Zorbilmez C
- Zotto P
- Zou D
- Zuber A
- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Zychowski P
- Zygala L
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2021
- Field of study
The very forward CASTOR calorimeter of the CMS experiment
- Author
- Aarrestad T. K.
- Abbaneo D.
- Abbiendi G.
- Abbrescia M.
- Abdalla H.
- Abdullah W. A. T. Wan
- Abdullin S.
- Abercrombie D.
- Acharya H.
- Acosta D.
- Acosta J. G.
- Adam W.
- Adamov G.
- Adams E.
- Adams M. R.
- Adams T.
- Adan D. Perez
- Adloff C.
- Adzic P.
- Afanasiev S.
- Agapitos A.
- Agarwal G.
- Aggleton R.
- Agram J. -L.
- Aguilar-Benitez M.
- Agyel D.
- Ahmad A.
- Ahmad M.
- Ahmad W. Haj
- Ahmed A.
- Ahuja S.
- Aida Junior W. L.
- Akbiyik M.
- Akchurin N.
- Akgun B.
- Akpinar A.
- Al-Bataineh A.
- Albajar C.
- Albergo S.
- Albert A.
- Albrow M.
- Alcaraz Maestre J.
- Aleksandrov A.
- Alexander J.
- Alhusseini M.
- Alimena J.
- Alison J.
- Allen B.
- Almond J.
- Alvarez Fernandez A.
- Alvarez Gonzalez B.
- Alverson G.
- Alves G. A.
- Aly R.
- Alyari M.
- Amapane N.
- Ambrogi F.
- Amendola C.
- Amin N.
- Amram O.
- Amsler C.
- Anagnostou G.
- Anagul S.
- Anampa K. Hurtado
- Anderson D.
- Andrea J.
- Andreev V.
- Andreev Yu.
- Andrews M. B.
- Androsov K.
- Ang L.
- Angioni G. L. Pinna
- Antchev G.
- Antunovic Z.
- Apanasevich L.
- Apollinari G.
- Appelt E.
- Apresyan A.
- Apyan A.
- Araujo M.
- Arcaro D.
- Arcidiacono R.
- Arenton M. W.
- Argiro S.
- Arneodo M.
- Aruta C.
- Asavapibhop B.
- Asawatangtrakuldee C.
- Asenov P.
- Asghar M. I.
- Asilar E.
- Askew A.
- Aslanoglou X.
- Asmuss P.
- Atakisi I. O.
- Atanasov I.
- Ather M. W.
- Attikis A.
- Auffray E.
- Aushev T.
- Auzinger G.
- Avati V.
- Avery P.
- Avila C.
- Awan M. I. M.
- Ayala E.
- Azarkin M.
- Azhgirey I.
- Aziz T.
- Azzi P.
- Azzurri P.
- Baarmand M. M.
- Babaev A.
- Babounikau I.
- Bacchetta N.
- Bachiller I.
- Bachtis M.
- Backhaus M.
- Baden A.
- Baechler J.
- Bagliesi G.
- Bahinipati S.
- Baillon P.
- Bainbridge R.
- Bakas G.
- Bakhshiansohi H.
- Bakirci M. N.
- Ball A. H.
- Ban Y.
- Band R.
- Banerjee S.
- Banerjee S.
- Banos L. I. Estevez
- Bansal S.
- Barbagli G.
- Barberis E.
- Bargassa P.
- Baringer P.
- Barnes V. E.
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- Publication venue
- 'IOP Publishing'
- Publication date
- 26/11/2020
- Field of study
The physics motivation, detector design, triggers, calibration, alignment, simulation, and overall performance of the very forward CASTOR calorimeter of the CMS experiment are reviewed. The CASTOR Cherenkov sampling calorimeter is located very close to the LHC beam line, at a radial distance of about 1cm from the beam pipe, and at 14.4m from the CMS interaction point, covering the pseudorapidity range of −6.6 < η < −5.2. It was designed to withstand high ambient radiation and strong magnetic fields. The performance of the detector in measurements of forward energy density, jets, and processes characterized by rapidity gaps, is reviewed using data collected in proton and nuclear collisions at the LHC
The very forward CASTOR calorimeter of the CMS experiment
- Author
- Aarrestad T. K.
- Abbaneo D.
- Abbiendi G.
- Abbrescia M.
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- Abdullah W. A. T. Wan
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- Publication venue
- Publication date
- 01/01/2021
- Field of study
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
- Adamou Harissou
- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
- Akbar Sana Amir
- Akeel Nouf
- Akeem Aderogba Adeleke
- Akin Alp
- Akinkuolie Akinbolaji
- Akisheva Aygulya
- Akitikori Mabel Temisanren
- Akrida Ioanna
- Aktas Melik Kagan
- Al basos Iyad
- Al Farsi Maryam
- Al Nassrallah Majdi
- Al Sagheir Eman
- Al Saqqa Sara
- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
- AlBsoul Ahmad
- Albsoul Nader
- Alcorta Rodrigo
- Alejandre Villalobos Cristina
- Alemdag Gökçe nur
- Alexander Philip
- Alfarra Nada
- Alfitory Asma
- Alhabil Belal
- Alhaj Ahmad
- Alherz Mohammad
- Alhimyar Maryam
- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
- Ali Asmaa
- Ali Mahmoud
- Ali Shabina
- Alimi Marjan
- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
- Aljaber Dana
- Aljaberi Loay
- Aljanfi Asma
- Aljiffry Murad
- Aljohmani Lylas
- Alkhaledi Ahmad
- Alkhatib Ala'a Aldeen
- Alkhatib Haya
- Alkhatib Mo'min
- Allen Ingabire J.C.
- Almasri Murad
- Almeida Braga Sara
- Almeida Filipe
- Almigheerbi Alabas
- Almoqayyad Abdelrahman
- Almuzghi Fakhruddin
- Alnoury Mostafa
- Alonso Batanero Ester
- Alqadi Mohammad
- Alsaid Bayan
- Alsalameh Barah
- Alsallaq Osama
- Alser Osaid
- Alshaar Muhammad
- Alsharef Tagwa
- Alsharqawi Nourah
- Alswerki Mohammad
- Altaf Amna
- Altaf Rabiya
- AlTaweel Mohammed
- Althini Abdulmunem Ahmed Mustafa
- Altibi Ahmed M.
- Altinel Yuksel
- Altiner Saygin
- Altomare Donato Francesco
- Altumei Zohoor
- Alvarez Rivera Alvaro Eduardo
- Alvarez-Cano Alethia
- Alves do Canto Brum Homero
- Alves Daniela Macedo
- Alves Magda
- Alvi Abdul
- Alwaheidi Malak
- Alwali Abdallah
- Alwerfally AbdulMawlay
- Alwhaidi Noor
- Alyafi Amr
- Alzabti Fatima
- Alzahaf Ahmed
- AlZohour Mohammad
- Amadou Magagi Ibrahim
- Amandito Radhian
- Amarin Justin Z.
- Amaro Margarida
- Ambrazevicius Marijus
- Amendola Alfonso
- Amin Leila
- Amine Souadka
- Amjad Talal
- Amorim Edgar
- Amro Adham
- Anandan Premkumar
- Anas khalifa Rawda
- Anastasio Lorenzo
- Andersson Yvette
- Andreotti Dario
- Andrew David
- André Benoît
- Ang Sue Ean
- Angel Miguel
- Anggita Gultom Phebe
- Annapureddy Naga
- Anokhin Evgeny
- Ansaloni Luca
- Ansarei Dhirar
- Ansari Abdul Basit
- Antaky Marco
- Anthony Natasha
- Anthoulakis Christos
- Antonopoulou Maria Ioanna
- Anwar Mohamed
- Anwer Abdul Wahid
- Anyanwu Chikamuche
- Anyanwu Lofty-John
- Anyanwu Mercy Chinemerem
- Anyomih Theophilus Teddy Kojo
- Appukuttan Akhila
- Aquilino Fabrizio
- Archibald Jess
- Arciénega Yañez María del pilar
- Argentou Maria-Ioanna
- Argudo Nuria
- Argyriou Eleftherios Orestis
- Arias Madrid Natalia
- Aribi Sarra
- Arifin Ghafur Rasyid
- Arizpe Daniel
- Arnaud Alexis P
- Arora Bharti
- Arora Deeksha
- Arowolo Olukayode
- Arrangoiz Rodrigo
- Arslan Ekin
- Artigau Eva
- Ashfaq Ahsan
- Ashour Dina
- Ashour Firas
- Ashoushan Hana
- Ashraf Ahmed
- Ashraf Alaa
- Asif Ashar
- Asnel Dorisme
- Asok Anjitha
- Assa Rawan
- Assalhi Mohamed
- Asta Martina
- Asti Emanuele Luigi Giuseppe
- Atakul Onur
- Atallah Khalid
- Atanasov Boyko
- Atawneh Mohammad
- Athamneh Sarah
- Ather Muaaz
- Athisayaraj Thomas
- Atkociunas Aivaras
- Attia Mohamed
- Au Angela
- Awad Israa
- Awadallah Haneen
- Awaji Kholoud
- Awesat Eman
- Awolowo Ajibola
- Ayandipo Omobolaji
- Ayash Mohammad
- Ayau Fernanda
- Ayesh Kholoud
- Ayman El-sawy Esraa
- Ayoub Rami
- Aytac Erman
- Ayub Bushra
- Ayub Saima
- Ayyad Rawan
- Azevedo José
- Azodo Ijeoma
- Azzubia Joma
- B L Ashika
- Ba Mouhamadou Bachir
- Babaa Basheer
- Babirye Lilian
- Bacic Ivan
- Badr Esraa Tarek
- Badr Helmy
- Badran Abdul
- Badwe Rajendra
- Bafford Andrea Chao M.D.
- Baggaley Caitlin
- Bahroun Sumayyah Ghayth
- Baiao José Miguel
- Baiocchi Daniella
- Bairos Menezes Maria
- Baiu Ioana
- Bajilan Mohammad
- Bajomo Oreoluwa
- Bake Jacques
- Baki Bahadir Emre
- Bakoleas Panagiotis
- Balaawi Reem
- Balalis Dimitrios
- Balata Mohamed
- Balkarov Artem
- Ballouhey Quentin
- Balogun Olanrewaju
- Baloyiannis Ioannis
- Baltaci Ege
- Bamaca Ixcajoc Elvis Benjamin
- Banaz Tuba
- Banda Bitiel
- Banglani Muntaha
- Bani Hani Farah
- Bani hani Mohammad
- Bani hani Zeina
- Baniowda Muath
- Banks Alexander
- Bannister Sharon
- Baranyai Zsolt
- Barati Nastaran
- Barbosa Camacho Francisco José
- Barbosa José
- Bardos David
- Barendegere Venerand
- Barghuthi Lutfi
- Barhoush Ola
- Barnes Nicole
- Baronio Gianluca
- Barreda Zelaya Lilian Elizabeth
- Barrera López Francisco Javier
- Barsic Neven
- Barter Charlotte
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- Teh Jen
- Tejeda Garrido Jorge Carlos Guillermo
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- Tharanath Kavya
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- Theodorou Dimitrios
- Theodosopoulos Theodosios
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- Thomas Hannah
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- Thompson Joanna
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- van Berge Henegouwen Mark I.
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- Vaughan-Shaw Peter G
- Vaysse Charlotte
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- Vijaykumar D.K.
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- Watts Daniel
- Weiser Thomas G
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- Whitaker John
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- Widmer Lukas Werner
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- Williams Christopher Yee Khang
- Wills Vanessa
- Wilson Karim
- Wilson Michael
- Wimmer Kerstin
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- Winoto Hadi
- Winter Beatty Jasmine
- Winter Des
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- Wisselink Daan
- Wogensen Fredrik
- Wondoh Paul M.
- Wong Florence
- Wong Hsu Ven
- Wong Jane J
- Wong Jeremy
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- Wong Michael Pak-Kai
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- You Lucia
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- Yusuf Baasil
- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit