11,511 research outputs found
Disruption of the with no lysine kinase-STE20-proline alanine-rich kinase pathway reduces the hypertension induced by angiotensin II
Control of the chirality and polarity of magnetic vortices in triangular nanodots
Magnetic vortex dynamics in lithographically prepared nanodots is currently a
subject of intensive research, particularly after recent demonstration that the
vortex polarity can be controlled by in-plane magnetic field. This has
stimulated the proposals of non-volatile vortex magnetic random access
memories. In this work, we demonstrate that triangular nanodots offer a real
alternative where vortex chirality, in addition to polarity, can be controlled.
In the static regime, we show that vortex chirality can be tailored by applying
in-plane magnetic field, which is experimentally imaged by means of
Variable-Field Magnetic Force Microscopy. In addition, the polarity can be also
controlled by applying a suitable out-of-plane magnetic field component. The
experiment and simulations show that to control the vortex polarity, the
out-of-plane field component, in this particular case, should be higher than
the in-plane nucleation field. Micromagnetic simulations in the dynamical
regime show that the magnetic vortex polarity can be changed with
short-duration magnetic field pulses, while longer pulses change the vortex
chirality.Comment: 18 pages, 11 figure
Modulational and Parametric Instabilities of the Discrete Nonlinear Schr\"odinger Equation
We examine the modulational and parametric instabilities arising in a
non-autonomous, discrete nonlinear Schr{\"o}dinger equation setting. The
principal motivation for our study stems from the dynamics of Bose-Einstein
condensates trapped in a deep optical lattice. We find that under periodic
variations of the heights of the interwell barriers (or equivalently of the
scattering length), additionally to the modulational instability, a window of
parametric instability becomes available to the system. We explore this
instability through multiple-scale analysis and identify it numerically. Its
principal dynamical characteristic is that, typically, it develops over much
larger times than the modulational instability, a feature that is qualitatively
justified by comparison of the corresponding instability growth rates
On the role of continuing currents in lightning-induced fire ignition
Lightning flashes are an important source of wildfires worldwide, contributing to the emission of trace gases to the atmosphere. Based on experiments and field observation, continuing cur rents in lightning have since a long time been proposed to play a significant role in the ignition of wildfires. However, simultaneous detections of optical and radio signals from fire-igniting lightning confirming the role of continuing currents in igniting wildfires are rare. In this work, we first
analyze the optical signal of the lightning-ignited wildfires reported by the Geostationary Lightning Mapper over the Contiguous United States (CONUS) during the summer of 2018, and we then analyze the optical and the Extremely Low Frequency signal of a confirmed fire-igniting lightning flash in the Swiss Alps. Despite data uncertainties, we found that the probability of ignition of a lightning flash with Continuing Current (CC) lasting more than 10 ms is higher than that of cloud-to-ground lightning in CONUS. Finally, we confirm the existence of a long continuing current (lasting about 400 ms) associated with a long-lasting optical signal (lasting between 2 and 4 s) of a video-recorded fire-igniting lightning flash
Detection of continuing currents in lightning and lightning-ignited wildfires from geostationary orbit
Using perturbation methods and Laplace–Padé approximation to solve nonlinear problems
WOS: 000328081500009In this paper, the perturbation method and Pade transformation are used to provide an approximate solution of elliptic integrals of the second kind and of complete integrals of the first kind. Besides, we used the obtained results to calculate an analytic expression for the period of a simple pendulum. The method has an acceptable accuracy for high values of the initial amplitude, compared to the relative error < 1.7% for initial angles theta <= 70 degree
Escherichia coli and Staphylococcus aureus: bad news and good news from the European Antimicrobial Resistance Surveillance Network (EARS-Net), formerly EARSS), 2002 to 2009
Based on data collected by the European Antimicrobial Resistance Surveillance Network (EARS-Net) and the former EARSS, the present study describes the trends in antimicrobial susceptibility patterns and occurrence of invasive infections caused by Escherichia coli and Staphylococcus aureus in the period from 2002 to 2009. Antimicrobial susceptibility results from 198 laboratories in 22 European countries reporting continuously on these two microorganisms during the entire study period were included in the analysis. The number of bloodstream infections caused by E. coli increased remarkably by 71% during the study period, while bloodstream infections caused by S. aureus increased by 34%. At the same time, an alarming increase of antimicrobial resistance in E. coli was observed, whereas for S. aureus the proportion of meticillin resistant isolates decreased. The observed trend suggests an increasing burden of disease caused by E. coli. The reduction in the proportion of meticillin-resistant S. aureus and the lesser increase in S. aureus infections, compared with E. coli, may reflect the success of infection control measures at hospital level in several European countries.</p
Mesoscopic organization reveals the constraints governing C. elegans nervous system
One of the biggest challenges in biology is to understand how activity at the
cellular level of neurons, as a result of their mutual interactions, leads to
the observed behavior of an organism responding to a variety of environmental
stimuli. Investigating the intermediate or mesoscopic level of organization in
the nervous system is a vital step towards understanding how the integration of
micro-level dynamics results in macro-level functioning. In this paper, we have
considered the somatic nervous system of the nematode Caenorhabditis elegans,
for which the entire neuronal connectivity diagram is known. We focus on the
organization of the system into modules, i.e., neuronal groups having
relatively higher connection density compared to that of the overall network.
We show that this mesoscopic feature cannot be explained exclusively in terms
of considerations, such as optimizing for resource constraints (viz., total
wiring cost) and communication efficiency (i.e., network path length).
Comparison with other complex networks designed for efficient transport (of
signals or resources) implies that neuronal networks form a distinct class.
This suggests that the principal function of the network, viz., processing of
sensory information resulting in appropriate motor response, may be playing a
vital role in determining the connection topology. Using modular spectral
analysis, we make explicit the intimate relation between function and structure
in the nervous system. This is further brought out by identifying functionally
critical neurons purely on the basis of patterns of intra- and inter-modular
connections. Our study reveals how the design of the nervous system reflects
several constraints, including its key functional role as a processor of
information.Comment: Published version, Minor modifications, 16 pages, 9 figure
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