1,766 research outputs found
Acceptance and commitment therapy for symptom interference in metastatic breast cancer patients: a pilot randomized trial
PURPOSE:
Breast cancer is the leading cause of cancer mortality in women worldwide. With medical advances, metastatic breast cancer (MBC) patients often live for years with many symptoms that interfere with activities. However, there is a paucity of efficacious interventions to address symptom-related suffering and functional interference. Thus, this study examined the feasibility and preliminary efficacy of telephone-based acceptance and commitment therapy (ACT) for symptom interference with functioning in MBC patients.
METHODS:
Symptomatic MBC patients (N = 47) were randomly assigned to six telephone sessions of ACT or six telephone sessions of education/support. Patients completed measures of symptom interference and measures assessing the severity of pain, fatigue, sleep disturbance, depressive symptoms, and anxiety.
RESULTS:
The eligibility screening rate (64%) and high retention (83% at 8 weeks post-baseline) demonstrated feasibility. When examining within-group change, ACT participants showed decreases in symptom interference (i.e., fatigue interference and sleep-related impairment; Cohen's d range = - 0.23 to - 0.31) at 8 and 12 weeks post-baseline, whereas education/support participants showed minimal change in these outcomes (d range = - 0.03 to 0.07). Additionally, at 12 weeks post-baseline, ACT participants showed moderate decreases in fatigue and sleep disturbance (both ds = - 0.43), whereas education/support participants showed small decreases in these outcomes (ds = - 0.24 and - 0.18 for fatigue and sleep disturbance, respectively). Both the ACT and education/support groups showed reductions in depressive symptoms (ds = - 0.27 and - 0.28) at 12 weeks post-baseline. Group differences in all outcomes were not statistically significant.
CONCLUSIONS:
ACT shows feasibility and promise in improving fatigue and sleep-related outcomes in MBC patients and warrants further investigation
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Photoluminescence, recombination induced luminescence and electroluminescence in epoxy resin
Dielectric breakdown of epoxies is preceded by light emission, or so-called electroluminescence, from the solid-state material. Very little is known about the luminescence properties of epoxies. The aim of this paper is to derive information that can be used as a basis to understand the nature of the excited states and their involvement in electrical degradation processes. Three different kinds of stimulation were used to excite the material luminescence. Photoluminescence was performed on the base resin, the hardener and the cured resin. Luminescence excited by a silent discharge has been analysed to identify which of the luminescent centres are optically active upon the recombination of electrical charges and could therefore act as charge traps. Finally, the electroluminescence spectrum has been acquired and compared with the previous ones. Although the identification of the origin of these emissions is far from being complete, it has been found that the photoluminescence from the cured resin is due to in-chain chromophores, which acts as trapping centres. The excited states involved in photoluminescence also seems to be involved in electroluminescence, but other components are detected as well, which could be due to the degradation of the resin molecule under the effect of the electric stress
Creative and Stylistic Devices Employed by Children During a Storybook Narrative Task: A Cross-Cultural Study
Purpose: The purpose of this study was to analyze the effects of culture on the creative and stylistic features children employ when producing narratives based on wordless picture books.
Method: Participants included 60 first- and second-grade African American, Latino American, and Caucasian children. A subset of narratives based on wordless picture books collected as part of a larger study was coded and analyzed for the following creative and stylistic conventions: organizational style (topic centered, linear, cyclical), dialogue (direct, indirect), reference to character relationships (nature, naming, conduct), embellishment (fantasy, suspense, conflict), and paralinguistic devices (expressive sounds, exclamatory utterances).
Results: Many similarities and differences between ethnic groups were found. No significant differences were found between ethnic groups in organizational style or use of paralinguistic devices. African American children included more fantasy in their stories, Latino children named their characters more often, and Caucasian children made more references to the nature of character relationships.
Conclusion: Even within the context of a highly structured narrative task based on wordless picture books, culture influences children’s production of narratives. Enhanced understanding of narrative structure, creativity, and style is necessary to provide ecologically valid narrative assessment and intervention for children from diverse cultural backgrounds
Observations of radio pulses from CU Virginis
The magnetic chemically peculiar star CU Virginis is a unique astrophysical
laboratory for stellar magnetospheres and coherent emission processes. It is
the only known main sequence star to emit a radio pulse every rotation period.
Here we report on new observations of the CU Virginis pulse profile in the 13
and 20\,cm radio bands. The profile is known to be characterised by two peaks
of 100 circularly polarised emission that are thought to arise in an
electron-cyclotron maser mechanism. We find that the trailing peak is stable at
both 13 and 20\,cm, whereas the leading peak is intermittent at 13\,cm. Our
measured pulse arrival times confirm the discrepancy previously reported
between the putative stellar rotation rates measured with optical data and with
radio observations. We suggest that this period discrepancy might be caused by
an unknown companion or by instabilities in the emission region. Regular
long-term pulse timing and simultaneous multi-wavelength observations are
essential to clarify the behaviour of this emerging class of transient radio
source.Comment: Accepted by MNRAS Letters; 5 pages, 2 figures, 3 table
An Eccentric Binary Millisecond Pulsar in the Galactic Plane
Binary pulsar systems are superb probes of stellar and binary evolution and
the physics of extreme environments. In a survey with the Arecibo telescope, we
have found PSR J1903+0327, a radio pulsar with a rotational period of 2.15 ms
in a highly eccentric (e = 0.44) 95-day orbit around a solar mass companion.
Infrared observations identify a possible main-sequence companion star.
Conventional binary stellar evolution models predict neither large orbital
eccentricities nor main-sequence companions around millisecond pulsars.
Alternative formation scenarios involve recycling a neutron star in a globular
cluster then ejecting it into the Galactic disk or membership in a hierarchical
triple system. A relativistic analysis of timing observations of the pulsar
finds its mass to be 1.74+/-0.04 Msun, an unusually high value.Comment: 28 pages, 4 figures inc Supplementary On-Line Material. Accepted for
publication in Science, published on Science Express: 10.1126/science.115758
A MeerKAT view of the pulsars in the globular cluster NGC 6522
We present the results of observations aimed at discovering and studying
pulsars in the core-collapsed globular cluster (GC) NGC 6522 performed by the
MeerTIME and TRAPUM Large Survey Project with the MeerKAT telescope. We have
discovered two new isolated pulsars bringing the total number of known pulsars
in the cluster to six. PSR J18033002E is a mildly recycled pulsar with spin
period of 17.9 ms while pulsar PSR J18033002F is a slow pulsar with spin
period of 148.1 ms. The presence of isolated and slow pulsars is expected in
NGC 6522 and confirms the predictions of previous theories for clusters at this
stage in evolution. We further present a tentative timing solution for the
millisecond pulsar (MSP) PSR J18033002C combining older observations taken
with the Parkes 64m radio telescope, Murriyang. This solution implies a
relatively small characteristic age of the pulsar in contrast with the old age
of the GC. The presence of a slow pulsar and an apparently young MSP, both rare
in GCs, suggests that their formation might be linked to the evolutionary stage
of the cluster.Comment: 8 pages, 5 figues, 3 tables. Accepted for publication in Astronomy
and Astrophysic
A fast radio burst with a low dispersion measure
Fast radio bursts (FRBs) are millisecond pulses of radio emission of
seemingly extragalactic origin. More than 50 FRBs have now been detected, with
only one seen to repeat. Here we present a new FRB discovery, FRB 110214, which
was detected in the high latitude portion of the High Time Resolution Universe
South survey at the Parkes telescope. FRB 110214 has one of the lowest
dispersion measures of any known FRB (DM = 168.90.5 pc cm), and was
detected in two beams of the Parkes multi-beam receiver. A triangulation of the
burst origin on the sky identified three possible regions in the beam pattern
where it may have originated, all in sidelobes of the primary detection beam.
Depending on the true location of the burst the intrinsic fluence is estimated
to fall in the range of 50 -- 2000 Jy ms, making FRB 110214 one of the
highest-fluence FRBs detected with the Parkes telescope. No repeating pulses
were seen in almost 100 hours of follow-up observations with the Parkes
telescope down to a limiting fluence of 0.3 Jy ms for a 2-ms pulse. Similar
low-DM, ultra-bright FRBs may be detected in telescope sidelobes in the future,
making careful modeling of multi-beam instrument beam patterns of utmost
importance for upcoming FRB surveys.Comment: 8 pages, 3 figures, accepted for publication in MNRA
Pulsar Results with the Fermi Large Area Telescope
The launch of the Fermi Gamma-ray Space Telescope has heralded a new era in
the study of gamma-ray pulsars. The population of confirmed gamma-ray pulsars
has gone from 6-7 to more than 60, and the superb sensitivity of the Large Area
Telescope (LAT) on Fermi has allowed the detailed study of their spectra and
light curves. Twenty-four of these pulsars were discovered in blind searches of
the gamma-ray data, and twenty-one of these are, at present, radio quiet,
despite deep radio follow-up observations. In addition, millisecond pulsars
have been confirmed as a class of gamma-ray emitters, both individually and
collectively in globular clusters. Recently, radio searches in the direction of
LAT sources with no likely counterparts have been highly productive, leading to
the discovery of a large number of new millisecond pulsars. Taken together,
these discoveries promise a great improvement in the understanding of the
gamma-ray emission properties and Galactic population of pulsars. We summarize
some of the results stemming from these newly-detected pulsars and their timing
and multi-wavelength follow-up observations.Comment: 21 pages, 9 figures, to appear in Proceedings of ICREA Workshop on
The High-Energy Emission from Pulsars and their Systems, Sant Cugat, Spain,
2010 April 12-16 (Springer
Validation of a susceptibility, benefits, and barrier scale for mammography screening among Peruvian women: a cross-sectional study
<p>Abstract</p> <p>Background</p> <p>Perceived beliefs about breast cancer and breast cancer screening are important predictors for mammography utilization. This study adapted and validated the Champion's scale in Peru. This scale measures perceived susceptibility for breast cancer and perceived benefits and barriers for mammography.</p> <p>Methods</p> <p>A cross-sectional study was conducted among women ages 40 to 65 attending outpatient gynecology services in a public hospital in Peru. A group of experts developed and pre-tested a Spanish version of the Champion's scale to assess its comprehensibility (N = 20). Factor analysis, internal consistency, and test-retest reliability analyses were performed (N = 285). Concurrent validity compared scores from participants who had a mammogram and those who did not have it in the previous 15 months. T-test and multiple regression analysis adjusting for socio-demographic factors, mammography knowledge and other preventive behaviors were performed.</p> <p>Results</p> <p>The construct validity and reliability were optimal. Cronbach-Alpha coefficients were 0.75 (susceptibility), 0.72 (benefits) and 0.86 (barriers). Concurrent validity analysis showed an association between barriers and mammography screening use in bivariate (22.3 ± 6.7 vs. 30.2 ± 7.6; p < 0.001) and multiple regression analysis (OR = 0.28, 95% CI = 0.18-0.43). Ages 50-60 years (OR = 2.35, 95% CI = 1.19-4.65), history of prior Papanicolaou test (OR = 3.69, 95% CI = 1.84-7.40), and knowledge about breast cancer and mammography (OR = 3.69, 95% CI = 1.84-7.40) were also independently associated with mammography screening use.</p> <p>Conclusion</p> <p>Concurrent validity analysis showed that the Champion's scale has important limitations for assessing perceived susceptibility for breast cancer and perceived benefits for mammography among Peruvian women. There is still a need for developing valid and reliable instruments for measuring perceived beliefs about breast cancer and mammography screening among Peruvian women.</p
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