133 research outputs found

    Marcha Mundial de las Mujeres (MMM): activismo en red como factor de integración en América Latina

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    Para el presente ensayo, la investigadora partirá de la premisa de que hoy día el sistema internacional se encuentra sumido en un contexto de cambio profundo, producto de una creciente interdependencia ante el llamado proceso de globalización. Lo cual afecta las reglas del juego, los actores, sus pautas de comportamiento, sus relaciones de poder y sus formas de organización. Ante esta realidad existen nuevos retos. Entre ellos, la necesidad de una mayor cooperación para hacer frente a problemas globales que no se pueden solucionar por las vías estatales tradicionales (Echart, 2008). Internet se encuentra a la vanguardia de estos cambios. Con sólo pulsar un botón, las historias de ámbito local se difunden por todo elmundo. Es en estas circunstancias que aparecen otras fuerzas sociales que rompen con el antiguo esquema de actores internacionales. Dichas fuerzas, a través de la creación deredes ciudadanas globales mediante las tecnologías de información, juegan un rol central en los procesos de cambio (Echart, 2008). Esto abre paso a un interesante crisol de ideas dentro de una sociedad internacional en transformación. Se trata de la emergencia de movimientos ciudadanos a escala mundial, parte de la lucha contra laglobalización neoliberal. La aparición de estos nuevos sujetos se enmarca en el actualdebate sobre la democracia y la participación. Su ejercicio ya no se limita al ámbito estatal o regional, resulta necesario extenderlo a un contexto mucho más amplio.In this essay I propose that today’s international system is submerged in a context of profound changes, product of an interdependent and crescent process called globalization. This affects the rules of the game, the actors, their behavior trends, their power relations and their forms of organization. This new reality consists of new challenges, among them, the need for a greater cooperation to face global problems that cannot be solved only by the state (Echart, 2008). Internet is on the front of these changes. With just a mouse click, local histories can be viewed worldwide. Under these circumstances they appear other social forces that break with the past scenario of international actors. These forces, through the creation of global citynetworks by ICT, play an important role in change processes (Echart, 2008). This allows an interesting set of ideas within an international society in transformation. This will be analyzed throughout the essay.This paper reflects on the emergence of citizen movements that fight neoliberal globalization worldwide. The appearance of these new actors is frame worked in a current debate about democracy and participation. Their exercise is not limited to the state or regional sphere but to a wider context

    Geomagnetic anomalies observed at volcano Popocatepetl, Mexico

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    International audienceResults of the ULF geomagnetic monitoring of the volcano Popocatepetl (Mexico) and their analysis are summarized and presented for the period 2003?2006. Our analysis reveals some anomalies which are considered to be of local volcanic origin: the EM background in the vicinity of the volcano was found to be significantly noisier than at other reference stations; sporadic strong noise-like geomagnetic activity was observed in the H-component; some geomagnetic pulsations were observed only at the Tlamacas station (located at 4 km near the volcano). The results are discussed in terms of a physical mechanism involving the presence of a second magmatic chamber within the volcano and, finally, further perspective directions to study volcanic geodynamical processes besides the traditional ones are given

    Highly-Efficient Holmium-Doped All-Fiber ~2.07-µm Laser Pumped by Ytterbium-doped Fiber Laser at ~1.13 µm

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    We report a 2.07-µm Holmium-doped all-fiber laser (HDFL) pumped by a 1.13-µm Ytterbium-doped fiber laser (YDFL). Home-made alumino-germano-silicate holmium-doped fiber (HDF) served here as active medium, optimized in terms of chemical composition and co-dopants’ concentrations. Laser action at 2.07 µm was assessed in simple Fabry–Perot cavity, formed by a couple of home-made fiber Bragg gratings (FBGs), inscribed directly in the HDF; this allowed notable diminishing of intracavity loss of the 2.07-µm laser. HDF was in-core pumped by the 1.13-µm double-clad YDFL with power of ~12.5 W, in turn pumped in-clad by a laser diode (LD) operated at 0.97 µm with ~24.5-W output. Using optimal length (~5.0…5.5 m) of the HDF and employing FBG couplers with reflections of ~99% and ~33%, the HDFL provided ~5.0-W output at 2.07 µm. At these conditions, maximal absolute (slope) efficiencies at 2.07 µm of 39% (42%) and 20% (22%) were measured with respect to 1.13-µm (YDFL) and 0.97-µm (LD) pumps, respectively. Moreover, the record slope efficiency (48%) was obtained for the powers ratio of 2.07-µm output (HDFL) to launched 1.13-µm input (YDFL), which is only slightly less than theoretical quantum efficiency limit (53%) for this kind of pump schemes

    VOLUMEN 22, NÚMERO 37 (2000)

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    ANÁLISIS DE VARIABLES MORFOMÉTRICAS DE toxaster roulini agassiz (Echinoides: toxasteriidae) DE LA FORMACIÓN ROSA BLANCA, MUNICIPIO DE ZAPATOCA (SANTANDER, COLOMBIA). Cruz Guevara, L. E.; Jerez Jaimes, J. H., Narváez Parra, E. X.; Franco Blanco, R. A.COMPOSICIÓN QUÍMICA Y MINERALOGÍA DE LAS BIOTITAS METAMÓRFICAS DEL SECTOR CENTRAL DEL MACIZO DE SANTANDER, COLOMBIA. García Ramírez, C. A.; Campos Álvarez, N. O.BRECHAS DE ATRICIÓN Y MINERALIZACIONES AURÍFERAS EN LAS MINAS DE MIRAFLORES (QUINCHÍA, RISARALDA) Y SU RELACIÓN CON UN CUERPO TIPO “BRECHA - PIPE”. Carrillo Lombana, V. M.CRITERIOS PARA LA CLASIFICACIÓN Y DESCRIPCIÓN DE MOVIMIENTOS EN MASA. Vargas Cuervo, G.ANOMALÍAS GEOBOTÁNICAS ESPECTRALES ASOCIADAS CON LOS CAMBIOS EN LITOLOGÍA: SU USO PARA LA CARTOGRAFÍA GEOLÓGICA DE ROCAS ULTRABÁSICAS, EN TERRENOS TOTALMENTE VEGETADOS DE LA COSTA PACÍFICA COLOMBIANA. Villegas, V. H

    VOLUMEN 22, NÚMERO 37 (2000)

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    ANÁLISIS DE VARIABLES MORFOMÉTRICAS DE toxaster roulini agassiz (Echinoides: toxasteriidae) DE LA FORMACIÓN ROSA BLANCA, MUNICIPIO DE ZAPATOCA (SANTANDER, COLOMBIA). Cruz Guevara, L. E.; Jerez Jaimes, J. H., Narváez Parra, E. X.; Franco Blanco, R. A.COMPOSICIÓN QUÍMICA Y MINERALOGÍA DE LAS BIOTITAS METAMÓRFICAS DEL SECTOR CENTRAL DEL MACIZO DE SANTANDER, COLOMBIA. García Ramírez, C. A.; Campos Álvarez, N. O.BRECHAS DE ATRICIÓN Y MINERALIZACIONES AURÍFERAS EN LAS MINAS DE MIRAFLORES (QUINCHÍA, RISARALDA) Y SU RELACIÓN CON UN CUERPO TIPO “BRECHA - PIPE”. Carrillo Lombana, V. M.CRITERIOS PARA LA CLASIFICACIÓN Y DESCRIPCIÓN DE MOVIMIENTOS EN MASA. Vargas Cuervo, G.ANOMALÍAS GEOBOTÁNICAS ESPECTRALES ASOCIADAS CON LOS CAMBIOS EN LITOLOGÍA: SU USO PARA LA CARTOGRAFÍA GEOLÓGICA DE ROCAS ULTRABÁSICAS, EN TERRENOS TOTALMENTE VEGETADOS DE LA COSTA PACÍFICA COLOMBIANA. Villegas, V. H

    Intravitreal bevacizumab (Avastin®) for diabetic retinopathy at 24-months: The 2008 Juan Verdaguer-planas lecture

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    Diabetic retinopathy (DR) remains the major threat to sight in the working age population. Diabetic macular edema (DME) is a manifestation of DR that produces loss of central vision. Proliferative diabetic retinopathy (PDR) is a major cause of visual loss in diabetic patients. In PDR, the growth of new vessels is thought to occur as a result of vascular endothelial growth factor (VEGF) release into the vitreous cavity as a response to ischemia. Furthermore, VEGF increases vessel permeability leading to deposition of proteins in the interstitium that facilitate the process of angiogenesis and macular edema. This review demonstrates multiple benefits of intravitreal bevacizumab (IVB) on DR including DME and PDR at 24 months of follow up. The results indicate that IVB injections may have a beneficial effect on macular thickness and visual acuity (VA) in diffuse diabetic macular edema. Therefore, in the future this new therapy could replace or complement focal/grid laser photocoagulation in DME. In PDR, this new option could be an adjuvant agent to pan-retina photocoagulation so that more selective therapy may be applied. In addition, we report a series of patients in which tractional retinal detachment developed or progressed after adjuvant preoperative IVB in severe PDR. © 2010 Bentham Science Publishers Ltd

    Comparative Study of Tumor Targeting and Biodistribution of pH (Low) Insertion Peptides (pHLIP® Peptides) Conjugated with Different Fluorescent Dyes

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    Purpose Acidification of extracellular space promotes tumor development, progression, and invasiveness. pH (low) insertion peptides (pHLIP® peptides) belong to the class of pH-sensitive membrane peptides, which target acidic tumors and deliver imaging and/or therapeutic agents to cancer cells within tumors. Procedures Ex vivo fluorescent imaging of tissue and organs collected at various time points after administration of different pHLIP® variants conjugated with fluorescent dyes of various polarity was performed. Methods of multivariate statistical analyses were employed to establish classification between fluorescently labeled pHLIP® variants in multidimensional space of spectral parameters. Results The fluorescently labeled pHLIP® variants were classified based on their biodistribution profile and ability of targeting of primary tumors. Also, submillimeter-sized metastatic lesions in lungs were identified by ex vivo imaging after intravenous administration of fluorescent pHLIP® peptide. Conclusions Different cargo molecules conjugated with pHLIP® peptides can alter biodistribution and tumor targeting. The obtained knowledge is essential for the design of novel pHLIP®-based diagnostic and therapeutic agents targeting primary tumors and metastatic lesions

    Intravitreal bevacizumab in diabetic retinopathy. Recommendations from the Pan-American Collaborative Retina Study Group (PACORES): The 2016 knobloch lecture

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    The advent of intravitreal anti-vascular endothelial growth factor (anti-VEGF) medications has revolutionized the treatment of diabetic eye diseases. Herein, we report the outcomes of clinical studies carried out by the Pan-American Collaborative Retina Study Group (PACORES), with a specific focus on the efficacy of intravitreal bevacizumab in the management of diabetic macular edema and proliferative diabetic retinopathy. We will also discuss the use of intravitreal bevaci-zumab as a preoperative, adjuvant therapy before vitrectomy for prolif-erative diabetic retinopathy. Copyright © 2017 by Asia Pacific Academy of Ophthalmology
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