Construction of an Immigrant Integration Composite Indicator through the Partial Least Squares Structural Equation Model K-Means

Integration is a multidimensional process, which can take place in different ways and at different times in relation to each of the single economic, social, cultural, and political dimensions. Hence, examining every single dimension is important as well as building composite indexes simultaneously inclusive of all dimensions in order to obtain a complete description of a complex phenomenon and to convey a coherent set of information. In this paper, we aim at building an immigrant integration composite indicator (IICI), able to measure the different aspects related to integration such as employment, education, social inclusion, active citizenship, and on the basis of which to simultaneously classify territorial areas such as European regions. For this application, the data collected in 274 European regions from the European Social Survey (ESS), Round 8, on immigration have been used

Efficacy of radiofrequency ablation in autonomous functioning thyroid nodules. A systematic review and meta-analysis

Whether thermal ablation is effective to treat toxic thyroid nodules (TTN) is still unknown. Aim of this review was to achieve more robust evidence on the efficacy of radiofrequency ablation (RFA) in treating TTN in terms of TSH normalization, thyroid scintiscan, and volume reduction rate (VRR). A comprehensive literature search of PubMed/Medline and Scopus was performed in November 2018 to retrieve published studies. Original papers reporting TTN treated by RFA and later followed-up were eligible. Excluded were: articles not within this field, articles with unclear data, overlapping series, case/series reports. Discordances were solved in a final collegial meeting. Information was collected concerning population features, treatment procedure, follow-up, cases with TSH normalization, cases with scintiscan normalization, VRR of nodules. Pooled prevalence of patients with TSH or scintiscan normalization, and pooled VRR over time were calculated. For statistical analysis, the random-effects model was used. Eight articles published between 2008 and 2018 were included. The overall number of AFTN treated by RFA was 205. Five studies used a single session of treatment. The time of follow-up ranged from six to 24 months. The pooled rate of patients with TSH normalization was 57%. The pooled rate of patients with scintigraphically proven optimal response was 60%. The pooled VRR at 1 year was 79%. Baseline nodules volume was associated with the rate of TSH normalization. In conclusion, a moderate efficacy of RFA in treating TTN was found, and this can represent a solid starting point in this field

Chiral condensates from tau decay: a critical reappraisal

The saturation of QCD chiral sum rules is reanalyzed in view of the new and complete analysis of the ALEPH experimental data on the difference between vector and axial-vector correlators (V-A). Ordinary finite energy sum rules (FESR) exhibit poor saturation up to energies below the tau-lepton mass. A remarkable improvement is achieved by introducing pinched, as well as minimizing polynomial integral kernels. Both methods are used to determine the dimension d=6 and d=8 vacuum condensates in the Operator Product Expansion, with the results: {O}_{6}=-(0.00226 \pm 0.00055) GeV^6, and O_8=-(0.0053 \pm 0.0033) GeV^8 from pinched FESR, and compatible values from the minimizing polynomial FESR. Some higher dimensional condensates are also determined, although we argue against extending the analysis beyond dimension d = 8. The value of the finite remainder of the (V-A) correlator at zero momentum is also redetermined: \Pi (0)= -4 \bar{L}_{10}=0.02579 \pm 0.00023. The stability and precision of the predictions are significantly improved compared to earlier calculations using the old ALEPH data. Finally, the role and limits of applicability of the Operator Product Expansion in this channel are clarified.Comment: Replaced versio

Management of osteoporosis in men: A narrative review

Male osteoporosis is a still largely underdiagnosed pathological condition. As a conse-quence, bone fragility in men remains undertreated mainly due to the low screening frequency and to controversies in the bone mineral density (BMD) testing standards. Up to the 40% of overall osteo-porotic fractures affect men, in spite of the fact that women have a significant higher prevalence of osteoporosis. In addition, in males, hip fractures are associated with increased morbidity and mortality as compared to women. Importantly, male fractures occur about 10 years later in life than women, and, therefore, due to the advanced age, men may have more comorbidities and, consequently, their mortality is about twice the rate in women. Gender differences, which begin during puberty, lead to wider bones in males as compared with females. In men, follicle-stimulating hormones, testosterone, estrogens, and sex hormone-binding levels, together with genetic factors, interact in determining the peak of bone mass, BMD maintenance, and lifetime decrease. As compared with women, men are more frequently affected by secondary osteoporosis. Therefore, in all osteoporotic men, a complete clinical history should be collected and a careful physical examination should be done, in order to find clues of a possible underlying diseases and, ultimately, to guide laboratory testing. Currently, the pharmacological therapy of male osteoporosis includes aminobisphosphonates, denosumab, and teriparatide. Hypogonadal patients may be treated with testosterone replacement therapy. Given that the fractures related to mortality are higher in men than in women, treating male subjects with osteoporosis is of the utmost importance in clinical practice, as it may impact on mortality even more than in women

Europe is Not a Tree - L'Europa non è un albero

Redazionale del #7 della rivista ARDET

Italian association of clinical endocrinologists (AME) position statement: drug therapy of osteoporosis

Treatment of osteoporosis is aimed to prevent fragility fractures and to stabilize or increase bone mineral density. Several drugs with different efficacy and safety profiles are available. The long-term therapeutic strategy should be planned, and the initial treatment should be selected according to the individual site-specific fracture risk and the need to give the maximal protection when the fracture risk is highest (i.e. in the late life). The present consensus focused on the strategies for the treatment of postmenopausal osteoporosis taking into consideration all the drugs available for this purpose. A short revision of the literature about treatment of secondary osteoporosis due both to androgen deprivation therapy for prostate cancer and to aromatase inhibitors for breast cancer was also performed. Also premenopausal females and males with osteoporosis are frequently seen in endocrine settings. Finally particular attention was paid to the tailoring of treatment as well as to its duration

Study o f archaeological pottery from Paraná State em ploying nuclear non destructive techniques

Fragmentos de cerâmica indígena da região de Londrina, norte do estado do Paraná, sul do Brasil, pertencentes à coleção arqueológica do Museu “Padre Carlos Weiss” foram estudados por EDXRF, RBS e Transmissão de Raios Gama. Além da composição química da pasta cerâmica, também foi possível detectar alguns elementos dos vestígios da decoração plástica. Foram obtidas as composições quantitativas das pastas cerâmicas e comparadas com os resultados de análise química por espectroscopia de emissão atômica. Os fragmentos também foram analisados por transmissão de raios gama para inspecionar sua estrutura interna e homogeneidade. A análise densitométrica mostra claramente pastas cerâmicas bastante diferenciadas, tanto em homogeneidade como em densidade, sendo posssível a caracterização de algumas técnicas de manufatura da pasta, como a inclusão de pequenos fragmentos cerâmicos como antiplásticoIndian ceramic fragments from the region of Londrina, at the north of Paraná state, south of Brazil, belonging to the “Padre Carlos Weiss” Museum archaeological collection, were studied by EDXRF, RBS and Gamma Ray Transmission.Besides ceramic pastes’ elements, it was also possible to detect some elements of the plastic decoration remains. Quantitative determination of the pastes composition was obtained and compared with chemical analysis by atomic emission spectroscopy. The fragments were also analyzed by gamma ray transmission in order to inspect their internal structure and homogeneity. The densitometric analysis clearly showed very differentiated ceramic pastes, both in homogeneity and density, being possible the characterization of some ceramic paste manufacture techniques, as the inclusion of small ceramic fragments as antiplasti

estudo de cerâmica arqueologica do parana por tecnicas nucleares nao destrutivas

Fragmentos de cerâmica indígena da região de Londrina, norte do estado do Paraná, sul do Brasil, pertencentes à coleção arqueológica do Museu "Padre Carlos Weiss" foram estudados por EDXRF, RBS e Transmissão de Raios Gama. Além da composição química da pasta cerâmica, também foi possível detectar alguns elementos dos vestígios da decoração plástica. Foram obtidas as composições quantitativas das pastas cerâmicas e comparadas com os resultados de análise química por espectroscopia de emissão atômica. Os fragmentos também foram analisados por transmissão de raios gama para inspecionar sua estrutura interna e homogeneidade. A análise densitométrica mostra claramente pastas cerâmicas bastante diferenciadas, tanto em homogeneidade como em densidade, sendo posssível a caracterização de algumas técnicas de manufatura da pasta, como a inclusão de pequenos fragmentos cerâmicos como antiplástic